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Cardiopulmonary Comorbidity

04-06-2024 Pulmonary Hypertension News

Seralutinib shows promise in PAH patients

Seralutinib delivered via inhaler significantly reduces pulmonary vascular resistance in patients with pulmonary arterial hypertension.

Editor's Choice

New options for managing pulmonary embolisms

Several new therapies and techniques for treating pulmonary embolisms have emerged in recent years. What are the pros and cons of these new options?

MERIT-1 study continues to support macitentan for CTEPH

25-04-2024 Pulmonary Hypertension News

Macitentan significantly improves pulmonary vascular resistance in people with inoperable chronic thromboembolic pulmonary hypertension.

Acute vena cava thrombosis leading to obstructive shock

Open Access Venous Thrombosis Case Study

Following an orthopedic trauma and DVT, a patient received an inferior vena cava filter intended to prevent pulmonary embolism. However obstructive shock developed secondary to extensive inferior vena cava thrombosis caused by inadequate anticoagulant therapy. 

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Episode 3: Unravelling resistant hypertension

Why is it so difficult to diagnose and manage?

Resistant hypertension is a difficult to treat and often misunderstood phenomenon that continues to frustrate cardiologists. 

In this episode, Professors Morris Brown and Bryan Williams debate the causes of resistant hypertension and explore novel treatment options.

Prof. Morris Brown
Prof. Bryan Williams

Case Studies

Acute vena cava thrombosis leading to obstructive shock

Open Access Venous Thrombosis Case Study

Following an orthopedic trauma and DVT, a patient received an inferior vena cava filter intended to prevent pulmonary embolism. However obstructive shock developed secondary to extensive inferior vena cava thrombosis caused by inadequate anticoagulant therapy. 

Serious consequences of nitrous oxide abuse

Open Access Nitrous Oxide Case Study

An exceptional combination of polyneuropathy, bilateral pulmonary embolism, and severe pancytopenia related to vitamin B12 deficiency and hyperhomocysteinemia induced by recreational nitrous oxide use.

Current Reviews

Novel inhaled pulmonary vasodilators in adult cardiac surgery: a scoping review

Milrinone Review Article/Brief Review

Our methodology was informed by the “PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation.” 14 This scoping review is in adherence with PRISMA guidelines. The review protocol was preregistered with the Open Science Framework …

Pediatric three-dimensional quantitative cardiovascular computed tomography

Computed Tomography ESPR 2024, Seville

High-resolution, isotropic, 3-dimensional (D) data from pediatric cardiovascular computed tomography (CT) offer great potential for the accurate quantitative evaluation of pediatric cardiovascular and pulmonary vascular diseases. Recent pilot …

Evolving Applications of Echocardiography in the Evaluation of Left Atrial and Right Ventricular Strain

Open Access Echocardiography Echocardiography (JM Gardin and AH Waller, Section Editors)

Left ventricular (LV) strain is widely used in the detection of subclinical LV dysfunction (e.g., cancer treatment-related cardiac dysfunction), heart failure with preserved ejection fraction (HFpEF), the assessment of LV diastolic dysfunction …

Right Ventricle-Pulmonary Artery Coupling in Patients Undergoing Cardiac Interventions

Heart Surgery Congenital Heart Disease (RA Krasuski and G Fleming, Section Editors)

Interest in the right ventricle (RV) has increased as our understanding of its importance in pre-operative assessment, perioperative management, and post-operative prognosis in cardiac surgery has progressed [ 1 – 4 ]. The unique morphologic and …

Webinar | 16-05-2023 | 17:30 (CEST)

Keynote webinar | Spotlight on cardio-oncology

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández

Further Reading

Notch ratio in pulmonary flow predicts long-term survival after pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension

Open Access Pulmonary Hypertension Original Article

Chronic thromboembolic pulmonary hypertension (CTEPH) is a distinct form of pulmonary hypertension (PH) that is categorized in Group 4 according to the latest clinical classification of PH and current guidelines [ 1 – 3 ]. CTEPH occurs as a result …

Evolving Applications of Echocardiography in the Evaluation of Left Atrial and Right Ventricular Strain

Open Access Echocardiography Echocardiography (JM Gardin and AH Waller, Section Editors)

Left ventricular (LV) strain is widely used in the detection of subclinical LV dysfunction (e.g., cancer treatment-related cardiac dysfunction), heart failure with preserved ejection fraction (HFpEF), the assessment of LV diastolic dysfunction …

Clinical characteristics, imaging findings, management, and outcomes of patients with scimitar syndrome at a tertiary referral healthcare center in Colombia

Open Access Computed Tomography Original Paper

Scimitar Syndrome is part of a complex spectrum of congenital cardiovascular anomalies related to anomalous pulmonary venous return. Depending on the extent of involvement, treatment can be either expectant or surgical. Prognosis and survival have …

Frequency, characteristics and risk assessment of pulmonary arterial hypertension with a left heart disease phenotype

Open Access Pulmonary Hypertension Original Paper

A growing number of patients diagnosed with pulmonary arterial hypertension (PAH) has features suggestive of concomitant left heart disease (LHD), albeit not clinically overt, nor sufficient to cause an elevation in pulmonary artery wedge pressure …