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Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on modern management of frailty

LIVE: Thursday 17th October 2024, 18:00-19:30 (CEST)

Frailty has a significant impact on health and wellbeing, especially in older adults. Join our experts to understand the factors that contribute to the development of frailty and find out how to manage the condition and reduce the risk of disability, dependency, and mortality.
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Cardiopulmonary Comorbidity

Rodatristat ethyl inappropriate for PAH

Treatment with rodatristat ethyl may worsen pulmonary hemodynamics and cardiac function in adults with pulmonary arterial hypertension.

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Editor's Choice

Bone cement leakage causes intracardiac foreign bodies and PE

Patient presenting with chest tightness and dyspnea after surgery for thoracolumbar vertebral compression fracture. Multi-organ embolism was identified caused by bone cement leakage. 

Obesity-related venous thromboembolism

Obesity is a recognized risk factor for VTE, but what is the current understanding of VTE in people living with obesity, their clinical needs, and the therapeutic challenges they face?

Small LV size and HFpEF both increase mortality risk in COPD

Two distinct factors contribute to impaired left ventricular filling in patients with chronic obstructive pulmonary disease, both increasing the risk for all-cause mortality.

HF from a cutaneous hemangioma

Large cutaneous hemangiomas can be hemodynamically significant, resulting in high-output heart failure and pulmonary hypertension. Embolization and resection is effective and well-tolerated.

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Episode 3: Unravelling resistant hypertension

Why is it so difficult to diagnose and manage?

Resistant hypertension is a difficult to treat and often misunderstood phenomenon that continues to frustrate cardiologists. 

In this episode, Professors Morris Brown and Bryan Williams debate the causes of resistant hypertension and explore novel treatment options.

Prof. Morris Brown
Prof. Bryan Williams
Listen now

Latest News

Rodatristat ethyl inappropriate for PAH

Small LV size and HFpEF both increase mortality risk in COPD

Seralutinib shows promise in PAH patients

MERIT-1 study continues to support macitentan for CTEPH

Support for double combination therapy in PAH

Metabolic syndrome increases cardiopulmonary risk in people with poor lung function

Case Studies

Bone cement leakage causes intracardiac foreign bodies and PE

Patient presenting with chest tightness and dyspnea after surgery for thoracolumbar vertebral compression fracture. Multi-organ embolism was identified caused by bone cement leakage. 

HF from a cutaneous hemangioma

Large cutaneous hemangiomas can be hemodynamically significant, resulting in high-output heart failure and pulmonary hypertension. Embolization and resection is effective and well-tolerated.

Unusual cause of respiratory failure

A patient with type II respiratory failure and pulmonary hypertension was diagnosed with RYR1-related myopathy, highlighting the importance of considering congenital myopathies in the differential diagnosis.

Keynote webinar | Spotlight on cardio-oncology

  • Webinar | 16-05-2023 | 17:30 (CEST)

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
Watch now

Current Reviews

Pericardiotomy as a novel treatment for heart failure with preserved ejection fraction

The pericardium plays an important role in modulating cardiac performance and hemodynamics in patients with heart failure with preserved ejection fraction (HFpEF). Pericardial constraint increases filling pressures in patients with HFpEF …

Right ventricular function in mitral stenosis: plays a fundamental role

The importance of the right ventricle (RV) was neglected or forgotten for decades. The RV has an essential function in cardiovascular physiology and pathology. The RV dysfunction is one of the causes of morbidity and mortality in valvular heart …

Myeloproliferative Neoplasms and Cardiovascular Disease: A Review

Myeloproliferative neoplasms (MPN) are a heterogenous group of disorders of clonal hematopoiesis characterized by constitutive activation of the JAK/STAT signaling pathway leading to proliferation of blood cells. Cardiovascular disease (CVD) …

Acute Pulmonary Embolism: Evidence, Innovation, and Horizons

A broad spectrum of clinical presentations, prevalent knowledge gaps in prognostic assessment and advanced management, and a rapidly expanding armamentarium of options for reperfusion have established acute pulmonary embolism (PE) as one of the …

CME & eLearning

Webcast (Link opens in a new window)

1.0 Interprofessional Continuing Education (IPCE) credit, 1.0 AAPA Category 1 CME credits

DMD remains a progressive incurable disease, but advances in patient-centered care and treatment for cardiopulmonary dysfunction have helped to increase life expectancy. This program equips multidisciplinary teams, including pediatric neurologists, pediatricians, pulmonologists, cardiologists, and endocrinologists, with key knowledge and skills to enhance care throughout the patient journey.

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME

Further Reading

BMP10 reflects pre-capillary pulmonary hemodynamics: association of biomarkers and hemodynamic parameters in pulmonary hypertension

Pulmonary hypertension (PH) is a severe and complex disease characterized by abnormally high pressure in the pulmonary arteries that eventually leads to right ventricular dysfunction and failure [ 1 ]. In PH, both an elevation of left atrial …

Pleural and pericardial effusions as prognostic factors in patients with acute pulmonary embolism: a multicenter study

Acute pulmonary embolism (PE) is a potentially life-threatening cardiovascular disease with 30-day mortality rates ranging from 0.5% to over 20%, depending on clinical symptoms at presentation [ 1 – 3 ]. However, there are also low-risk clinical …

Biomarkers reflecting the pathogenesis, clinical manifestations, and guide therapeutic approach in systemic sclerosis: a narrative review

Systemic sclerosis (SSc) is a progressive autoimmune disorder that mainly affects the skin. There are other clinical manifestations as renal, pulmonary, cardiovascular, and gastrointestinal tract involvements. Based on the skin involvement there …

Four-Strata Risk Assessment in Patients with Pulmonary Arterial Hypertension Treated with Selexipag in Real-World Settings (EXPOSURE Study)

Assessment of 1-year mortality risk provides a basis for the management of patients with pulmonary arterial hypertension (PAH) and aids clinical decision-making [ 1 , 2 ]. The overall therapeutic goal is for patients to survive and display PAH …

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