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Cardiology Cardiac Arrhythmia

Cardiac Arrhythmia

Free for a limited time Congenital Heart Anomaly Review

Advances in fetal heart disease

Emerging techniques, modalities, and therapies are improving prenatal diagnosis, prognotication, and management of congenital heart disease and arrhythmias.

Editor's Choice

Challenges in left bundle branch area pacing

Open Access Atrioventricular Block Case Study

Left bundle branch area pacing, which captures the left conduction system and progresses along the Purkinje system, is a novel pacing technique that shows promise. However these two cases describe procedural complications to be wary of. 

Stroke–heart syndrome

Open Access Stroke Review

How does stroke contribute to cardiac complications, such as arrhythmia, myocardial injury, and cardiac dysfunction? Typically peaking within 72 hours of stroke onset, these cardiac alterations can have long-term effects on cardiac function.

Is dexmedetomidine cardioprotective?

Dexmedetomidine, a highly selective α2 adrenergic receptor agonist, is used to manage pain and sedation during surgery and in the ICU. It's thought to have protective effects against cardiac injury, but what does the evidence show?

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Episode 3: Unravelling resistant hypertension

Why is it so difficult to diagnose and manage?

Resistant hypertension is a difficult to treat and often misunderstood phenomenon that continues to frustrate cardiologists. 

In this episode, Professors Morris Brown and Bryan Williams debate the causes of resistant hypertension and explore novel treatment options.

Prof. Morris Brown
Prof. Bryan Williams

Case Studies

Challenges in left bundle branch area pacing

Open Access Atrioventricular Block Case Study

Left bundle branch area pacing, which captures the left conduction system and progresses along the Purkinje system, is a novel pacing technique that shows promise. However these two cases describe procedural complications to be wary of. 

BRASH syndrome with digoxin toxicity

Open Access Bradyarrhythmia Case Study

BRASH syndrome (bradycardia, renal failure, atrioventricular node blocking, shock, and hyperkalemia), in this case triggered by extreme dehydration, was complicated by concomitant digoxin.

Takotsubo cardiomyopathy following pacemaker insertion

Open Access Cardiomyopathy Case Study

Takotsubo cardiomyopathy is a novel form of reversible heart failure mimicking an acute coronary event. Would you have made the correct the diagnosis in this patient?

Webinar | 16-05-2023 | 17:30 (CEST)

Keynote webinar | Spotlight on cardio-oncology

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández

Current Reviews

Unraveling the Complex Relationship—Atrial Fibrillation and Pulmonary Hypertension

Pulmonary Hypertension Invasive Electrophysiology and Pacing (EK Heist and S Nedios, Section Editors)

Pulmonary hypertension is a cardio-pulmonary disorder diagnosed when the mean pulmonary artery pressure (mPAP) ≥ 20 mmHg at rest and a progressive increase in pulmonary vascular resistance is observed, which eventually leads to right ventricular …

Conduction System Pacing: Hope, Challenges, and the Journey Forward

Cardiac Resynchronization Therapy Invasive Electrophysiology and Pacing (EK Heist and S Nedios, Section Editors)

The yearly number of cardiac implantable electronic device (CIED)-related procedures is high and projected to increase further due to demographic changes and a rising number of interventions that are associated with a high risk of subsequent …

Contact-force local impedance algorithm to guide effective pulmonary vein isolation in AF patients: 1-year outcome from an international multicenter clinical setting

Catheter ablation targeting pulmonary vein (PV) isolation is a well-established treatment for the prevention of AF recurrences [ 1 ]. The probability of achieving durable PV isolation (PVI) is influenced by the effectiveness of ablation energy …

Biophysics of Radiofrequency Ablation for Cardiac Arrhythmias: A Current Review

Radiofrequency (RF) catheter ablation has been the primary energy source in cardiac electrophysiology for over 30 years, facilitating a safe, effective, and minimally invasive treatment option for the treatment of cardiac arrhythmias. This method …

Further Reading

Predictors of ventricular tachyarrhythmia in patients with a wearable cardioverter defibrillator: an international multicenter registry

Open Access Ventricular Tachycardia ORIGINAL RESEARCH

Patients with a reduced left ventricular ejection fraction (LVEF) ≤ 35% are at increased risk of sudden cardiac death (SCD) [ 1 , 2 ]. Some patients may experience an improvement in LVEF after optimal medical treatment (OMT), leading current …

Long-Term Stimulation of the Left Dorsal Branch of the Thoracic Nerve Improves Ventricular Electrical Remodeling in a Canine Model of Chronic Myocardial Infarction

Open Access Myocardial Infarction Original Article

Malignant ventricular arrhythmias (VAs) remain the major and direct cause of sudden cardiac death (SCD) in patients with myocardial infarction (MI) [ 1 ]. The occurrences of VAs and SCD are closely associated with cardiac sympathetic hyperactivity …

Elevated plasma protein carbonylation increases the risk of ischemic cerebrovascular events in patients with atrial fibrillation: association with a prothrombotic state

Oxidative stress, the imbalance between reactive oxygen species (ROS) generation and antioxidant capacity [ 1 ], leads to a variety of oxidative protein modifications including carbonylation, which is a direct, metal catalyzed reaction with …

Impact of SGLT2 Inhibitors on Atrial Fibrillation Recurrence after Catheter Ablation in Type 2 Diabetes Mellitus: A Meta-Analysis of Reconstructed Kaplan–Meier Curves with Trial Sequential Analysis

Open Access Atrial Fibrillation Systematic Review

Atrial fibrillation (AF) is the most commonly encountered arrhythmia in clinical practice, and it is well established that there is a strong link between AF and type 2 diabetes mellitus (T2DM). Extensive research has consistently shown that …