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Circulatory Disease

Open Access Obesity Review

Sarcopenic obesity and cardiovascular disease

Sarcopenic obesity is an emerging risk factor for CVD, particularly in older adults. Optimizing its treatment and management will become increasingly important as the global population ages.

Editor's Choice

SGLT2 inhibitors a more effective second-line type 2 diabetes treatment?

22-05-2024 Type 2 Diabetes News

Real-world study data indicate that second-line treatment with SGLT2 inhibitors is more effective than with sulfonylureas or DPP-4 inhibitors for patients already taking metformin.


Hypotensive twilight zone in Parkinson’s disease

Free for a limited time Parkinson's Disease Case Study

Almost daily episodes of reduced responsiveness lasting up to an hour, with the patient slumped back in a chair but staying upright, indicated an under-recognised presentation of orthostatic hypotension.

Does intestinal permeability have a role in hypertension?

Open Access Hypertension Review

Evidence from animal models supports the presence of intestinal barrier dysfunction in hypertension, but what is the evidence in humans? Could hypertension increase gut permeability, or vice versa?

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Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Episode 3: Unravelling resistant hypertension

Why is it so difficult to diagnose and manage?

Resistant hypertension is a difficult to treat and often misunderstood phenomenon that continues to frustrate cardiologists. 

In this episode, Professors Morris Brown and Bryan Williams debate the causes of resistant hypertension and explore novel treatment options.

Prof. Morris Brown
Prof. Bryan Williams

Case Studies

Hypotensive twilight zone in Parkinson’s disease

Free for a limited time Parkinson's Disease Case Study

Almost daily episodes of reduced responsiveness lasting up to an hour, with the patient slumped back in a chair but staying upright, indicated an under-recognised presentation of orthostatic hypotension.

Profound hypotension induced by ICI treatment

A case of extreme hypotension that could have been prevented or mitigated with awareness of the underlying hypothyroidism related to nivolumab treatment.

Unique presentation of memantine overdose

Open Access Medical Side Effect Case Study

Hypertensive urgency and echolalia were the most striking symptoms of memantine overdose in an elderly man with mild dementia and hypertension. Early medication review with caregivers of people with dementia is key.

Current Reviews

Novel inhaled pulmonary vasodilators in adult cardiac surgery: a scoping review

Milrinone Review Article/Brief Review

Our methodology was informed by the “PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation.” 14 This scoping review is in adherence with PRISMA guidelines. The review protocol was preregistered with the Open Science Framework …

Management of Portal Hypertension in the Older Patient

WHO declared the commencement of aging of global population. Currently, people above the age of 60 years account for 1 billion of the world’s population, and the number is expected to increase to 2.1 billion by 2050 [ 1 ]. According to WHO Global …

Association Between Preeclampsia and Blood Pressure in Offspring: A Systematic Review and Meta-Analysis

Pre-Eclampsia Preeclampsia (VD Garovic and AG Kattah, Section Editors)

Preeclampsia is a multisystem pregnancy disorder defined as a common pregnancy complication with a new onset of hypertension after 20 weeks of gestation, often accompanied by proteinuria or other systemic diseases [ 1 ]. The overall estimate is …

Blood Pressure Management in Intracerebral Haemorrhage: when, how much, and for how long?

Open Access Stroke Review

Intracerebral haemorrhage (ICH) accounts for 15–30% of stroke and has high 30-day mortality of approximately 40%, with only 12 to 39% of patients achieving independent functional recovery [ 1 ]. While there have been many recent advances in …

Webinar | 16-05-2023 | 17:30 (CEST)

Keynote webinar | Spotlight on cardio-oncology

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
Developed by: Springer Medicine

Further Reading

Prevalence, Clustering, and Current Management of Cardiovascular Risk Factors Upon First Referral to Hypertension Specialists: the APPROACH Study

Open Access Hypertension Original article

With nearly 18 million deaths annually, cardiovascular disease (CVD) is the leading cause of premature mortality for non-communicable diseases (NCDs) worldwide, far exceeding the burden associated with the next most common NCDs, namely cancer …

High body mass index and triglyceride levels at health checkups increase the risk of new-onset chronic kidney disease and worsening renal function: the TAMA MED Project-CKD

Open Access Chronic Kidney Disease Original article

Chronic kidney disease (CKD) is an urgent issue that needs to be addressed as the number of patients requiring dialysis is increasing worldwide. It is a serious risk factor for cardiovascular diseases and has a significant impact on the health of …

Isometric Exercise Training and Arterial Hypertension: An Updated Review

Open Access Arterial Hypertension Review Article

Hypertension is recognised as a leading attributable risk factor for cardiovascular disease and premature mortality. Global initiatives towards the prevention and treatment of arterial hypertension are centred around non-pharmacological lifestyle …

White Coat Hypertension & Cardiovascular Outcomes

Open Access Hypertension Hypertension and the Heart (B Upadhya, Section Editor)

At present, our presupposition is that most readers will have an idea about what a “white coat effect” is. Pursuing that further, ask yourself the following seven questions: How would you define a white coat effect? Does it matter how you measure …

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