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Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on modern management of frailty

LIVE: Thursday 17th October 2024, 18:00-19:30 (CEST)

Frailty has a significant impact on health and wellbeing, especially in older adults. Join our experts to understand the factors that contribute to the development of frailty and find out how to manage the condition and reduce the risk of disability, dependency, and mortality.
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Valvular Heart Disease

Worsening heart failure in a survivor of cancer as a young adult

Severe cardiomyopathy presenting 20 years after anthracycline treatment for non-Hodgkin’s lymphoma during early adulthood. The patient's worsening heart failure was successfully managed with multidrug treatment with add-on vericiguat and ivabradine based on quadruple therapy. 

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Editor's Choice

A troublesome lower limb arteriovenous malformation

Acute heart failure was triggered by a congenital arteriovenous malformation in the lower limb. An abdominal aortic stent graft and embolization effectively resolved the issue. 

High lipoprotein(a) levels increase risk of coronary disease progression

Elevated lipoprotein(a) levels are associated with an increased risk for progression of coronary plaque burden and aortic stenosis.

Immunotherapy for aortic valve disease

Could T-cell therapy be an exciting new option for aortic valve disease? Targeting the lipid nanoparticles that are responsible for cardiac fibrosis might offer a non-surgical option for treatment.

Osteosarcopenia and mortality in patients undergoing TAVR

Older adults undergoing transcatheter aortic valve replacement who have osteosarcopenia are at increased risk for mortality and worsening disability.

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Keynote webinar | Spotlight on cardio-oncology

  • Webinar | 16-05-2023 | 17:30 (CEST)

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
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Latest News

High lipoprotein(a) levels increase risk of coronary disease progression

Osteosarcopenia and mortality in patients undergoing TAVR

Valve surgery beneficial in rheumatic heart disease

LANDMARK trial strengthens case for individualized TAVI

Reassuring aortic valve area? Don't be fooled

Self-expanding vs balloon-expandable TAVR

Case Studies

Worsening heart failure in a survivor of cancer as a young adult

Severe cardiomyopathy presenting 20 years after anthracycline treatment for non-Hodgkin’s lymphoma during early adulthood. The patient's worsening heart failure was successfully managed with multidrug treatment with add-on vericiguat and ivabradine based on quadruple therapy. 

A troublesome lower limb arteriovenous malformation

Acute heart failure was triggered by a congenital arteriovenous malformation in the lower limb. An abdominal aortic stent graft and embolization effectively resolved the issue. 

Frozen elephant trunk technique

Successful use of the frozen elephant surgical technique in a patient with acute aortic dissection, with full recovery and no incidence of any neurological side effects.

Current Reviews

Right ventricular function in mitral stenosis: plays a fundamental role

The importance of the right ventricle (RV) was neglected or forgotten for decades. The RV has an essential function in cardiovascular physiology and pathology. The RV dysfunction is one of the causes of morbidity and mortality in valvular heart …

Echocardiographic assessment of atrial, ventricular, and valvular function in patients with atrial fibrillation—an expert proposal by the german working group of cardiovascular ultrasound

Echocardiography in patients with atrial fibrillation is challenging due to the varying heart rate. Thus, the topic of this expert proposal focuses on an obvious gap in the current recommendations about diagnosis and treatment of atrial …

Editorial comment: echocardiography in atrial fibrillation: overcoming challenges and embracing innovations

Efficacy and Safety of Non-Vitamin K Antagonist Oral Anticoagulants Compared with Vitamin K Antagonists in Patients with Atrial Fibrillation and Type 2 Valvular Heart Disease: A Systematic Review and Meta-Analysis

Atrial fibrillation (AF) and valvular heart disease (VHD) frequently coexist, often presenting as an enlarged left atrium and influenced by a range of risk factors including aging, hypertension, diabetes mellitus, ischemic heart disease, and heart …

Further Reading

Prognostic impact of disease-related complications in asymptomatic mitral regurgitation: a health insurance claims analysis

Mitral regurgitation (MR) is the most common valvular heart disease (VHD) in adults [ 1 ]. Over 18 million cases of degenerative MR have been estimated globally, whereas the prevalence nearly doubled over the last 2 decades [ 1 ]. Furthermore, a …

Echocardiographic assessment of atrial, ventricular, and valvular function in patients with atrial fibrillation—an expert proposal by the german working group of cardiovascular ultrasound

Echocardiography in patients with atrial fibrillation is challenging due to the varying heart rate. Thus, the topic of this expert proposal focuses on an obvious gap in the current recommendations about diagnosis and treatment of atrial …

Efficacy and Safety of Non-Vitamin K Antagonist Oral Anticoagulants Compared with Vitamin K Antagonists in Patients with Atrial Fibrillation and Type 2 Valvular Heart Disease: A Systematic Review and Meta-Analysis

Atrial fibrillation (AF) and valvular heart disease (VHD) frequently coexist, often presenting as an enlarged left atrium and influenced by a range of risk factors including aging, hypertension, diabetes mellitus, ischemic heart disease, and heart …

Clot lysis time and thrombin generation in patients undergoing transcatheter aortic valve implantation

Treating severe aortic valve stenosis (AS) with transcatheter aortic valve implantation (TAVI) significantly reduced clot lysis time (CLT) by 9% despite a 12% increase in fibrinogen concentration. After TAVI, there was a notable increase in lag …

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