Skip to main content
Cardiology Heart Failure

Heart Failure

Editor's Choice

Hypertrophic cardiomyopathy is a complicated, heterogeneous genetic condition that causes left ventricular hypertrophy, fibrosis, and hypercontractility. Emerging therapies targeting a range of pathophysiological pathways are now entering the market.

The aldosterone synthase inhibitor lorundrostat significantly lowers blood pressure versus placebo in people with inadequately controlled hypertension on maximal antihypertensive therapy.

Iron deficiency, one of the most prevalent nutritional deficiencies worldwide, is a common comorbidity in heart failure. Understanding the underpinning pathophysiology and bioavailability of iron is clinically essential.

Case Studies

Endomyocardial fibrosis is the most frequent restrictive cardiomyopathy, with high prevalence in tropical regions. The disease's trademark is the fibrotic obliteration of the affected ventricle, which leads to endocardial thickening and fibrosis.

A collection of cases indicating the existence of extraventricular aortic stenosis in transthyretin cardiac amyloidosis (ATTR) amyloid deposits, localized in the aortic valve and left atrial structures.

Cardiac sarcoidosis is found to occur in approximately 5% of patients with sarcoidosis. Its presentation can typically range from complete heart block to ventricular arrhythmias. This case reports initial presentation with non-ST elevation myocardial infarction and acute renal failure. 

Episode 5: Next-generation sequencing

Emerging biomarkers in thyroid and non-small cell lung cancers

Next-generation sequencing is a powerful tool that can identify mutations or fusions in a wide range of cancers, enabling physicians to provide targeted therapy to patients and improve outcomes. In this podcast, Professor Andrew Beggs discusses practical aspects of this technique from the clinical viewpoint.

This content is intended only for healthcare providers and was made possible by educational funding provided by Illumina, Inc., and Eli Lilly and Company.

Listen now

Our tailored content service will keep you up to date…

Receive newsletters curated for the busy specialist by our expert editorial team

Further Reading