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Cardiology Heart Failure

Heart Failure

Free for a limited time Cardiac Diagnostics Review

Cardio-rheumatology: an emerging specialty

Cardio-rheumatology is an emerging subspecialty within cardiology that focuses on addressing the intricate relationship between systemic inflammation and CV diseases. Discover the most common manifestations as well as the recommended diagnostic workup and imaging options. 

Editor's Choice

Suboptimal CKD screening in people with type 2 diabetes

08-07-2024 Diabetic Nephropathy News

As many as three-quarters of US adults with type 2 diabetes are not being routinely screened for indicators of chronic kidney disease.

Stroke–heart syndrome

Open Access Stroke Review

How does stroke contribute to cardiac complications, such as arrhythmia, myocardial injury, and cardiac dysfunction? Typically peaking within 72 hours of stroke onset, these cardiac alterations can have long-term effects on cardiac function.

Carney syndrome-induced cardiac myxoma

Open Access Carney Complex Case Study

Carney syndrome is a rare autosomal genetic disorder characterised by myxomas, skin pigmentation, and endocrine hyperfunction. In this case cardiac myxoma caused by Carney syndrome combined with heart failure resulted in heart transplantation.

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Episode 3: Unravelling resistant hypertension

Why is it so difficult to diagnose and manage?

Resistant hypertension is a difficult to treat and often misunderstood phenomenon that continues to frustrate cardiologists. 

In this episode, Professors Morris Brown and Bryan Williams debate the causes of resistant hypertension and explore novel treatment options.

Prof. Morris Brown
Prof. Bryan Williams

Case Studies

Carney syndrome-induced cardiac myxoma

Open Access Carney Complex Case Study

Carney syndrome is a rare autosomal genetic disorder characterised by myxomas, skin pigmentation, and endocrine hyperfunction. In this case cardiac myxoma caused by Carney syndrome combined with heart failure resulted in heart transplantation.

HF from a cutaneous hemangioma

Hemangioma Case Study

Large cutaneous hemangiomas can be hemodynamically significant, resulting in high-output heart failure and pulmonary hypertension. Embolization and resection is effective and well-tolerated.

Overlooked effect of angiotensin receptor–neprilysin inhibitor

Caution is needed when assessing insulin secretion capability and nephropathy in patients with diabetes who are being treated with an angiotensin receptor–neprilysin inhibitor.

Webinar | 16-05-2023 | 17:30 (CEST)

Keynote webinar | Spotlight on cardio-oncology

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández

Current Reviews

Acetazolamide therapy in patients with acute heart failure: a systematic review and meta-analysis of randomized controlled trials

Acute heart failure (AHF) often leads to unfavorable outcomes due to fluid overload. While diuretics are the cornerstone treatment, acetazolamide may enhance diuretic efficiency by reducing sodium reabsorption. We performed a systematic review and …

Interplay of the heart, spleen, and bone marrow in heart failure: the role of splenic extramedullary hematopoiesis

Open Access Heart Failure Review

Improvements in therapies for heart failure with preserved ejection fraction (HFpEF) are crucial for improving patient outcomes and quality of life. Although HFpEF is the predominant heart failure type among older individuals, its prognosis is …

Current issues of destination therapy in Japan: to achieve 5−year or even longer survival

In April 2021, destination therapy (DT) was finally approved in Japan. Since DT does not aim at heart transplantation (HT), our goal is to have a patient safely remain on an implantable ventricular assist device (VAD) for the rest of his/her life.

Anti-obesity medications in the management of heart failure with preserved ejection fraction: available evidence and next STEPS

Semaglutide Mini Review

Obesity is associated with an increased risk of incident heart failure with preserved ejection fraction (HFpEF) and, among patients with existing heart failure, is associated with worse quality of life, higher symptom burden, and more HF …

Further Reading

Predictors of ventricular tachyarrhythmia in patients with a wearable cardioverter defibrillator: an international multicenter registry

Open Access Ventricular Tachycardia ORIGINAL RESEARCH

Patients with a reduced left ventricular ejection fraction (LVEF) ≤ 35% are at increased risk of sudden cardiac death (SCD) [ 1 , 2 ]. Some patients may experience an improvement in LVEF after optimal medical treatment (OMT), leading current …

Interplay of the heart, spleen, and bone marrow in heart failure: the role of splenic extramedullary hematopoiesis

Open Access Heart Failure Review

Improvements in therapies for heart failure with preserved ejection fraction (HFpEF) are crucial for improving patient outcomes and quality of life. Although HFpEF is the predominant heart failure type among older individuals, its prognosis is …

Current issues of destination therapy in Japan: to achieve 5−year or even longer survival

In April 2021, destination therapy (DT) was finally approved in Japan. Since DT does not aim at heart transplantation (HT), our goal is to have a patient safely remain on an implantable ventricular assist device (VAD) for the rest of his/her life.

Elevated plasma protein carbonylation increases the risk of ischemic cerebrovascular events in patients with atrial fibrillation: association with a prothrombotic state

Oxidative stress, the imbalance between reactive oxygen species (ROS) generation and antioxidant capacity [ 1 ], leads to a variety of oxidative protein modifications including carbonylation, which is a direct, metal catalyzed reaction with …