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23707 search results for:

Statins 

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  1. 01-04-2024 | Sarcopenia | News

    Statins reduce sarcopenia-related QOL in older men

  2. 29-04-2024 | Simvastatin | Online First

    Statins in Subarachnoid Hemorrhage to Prevent Delayed Cerebral Ischemia: Old Drugs for New Strategies?

  3. 30-04-2024 | Human Immunodeficiency Virus | Online First

    Letter to editor: Prophylactic use of statins in HIV patients: Better be safe than sorry

  4. 18-03-2024 | Parkinson's Disease | ReviewPaper

    The effects of cholesterol and statins on Parkinson’s neuropathology: a narrative review

    Parkinson disease (PD) is chronic and progressive neurodegenerative disease of the brain characterized by motor symptoms including tremors, rigidity, postural instability, and bradykinesia. PD neuropathology is due to the progressive degeneration …

  5. 14-02-2024 | Pneumonia | OriginalPaper

    Statins, ACE/ARBs drug use, and risk of pneumonia in hospitalized older patients: a retrospective cohort study

    The aims of this study is to evaluate the association between angiotensin-converting enzyme inhibitor (ACE-I), angiotensin II receptor blocker (ARBs) and/or statin use with the risk of pneumonia, as well as and with in-hospital and short-term …

  6. Open Access 01-12-2024 | Diabetic Retinopathy | OriginalPaper

    Statins as a risk factor for diabetic retinopathy: a Mendelian randomization and cross-sectional observational study

    With a dramatic rise in the number of diabetes mellitus (DM) worldwide, diabetic retinopathy (DR), a complication of DM that affects the vision of patients, is increasing the economic burden on human society and seriously affects the quality of …

  7. 02-02-2024 | OriginalPaper

    Statins affect human iPSC-derived cardiomyocytes by interfering with mitochondrial function and intracellular acidification

    Statins are effective drugs in reducing cardiovascular morbidity and mortality by inhibiting cholesterol synthesis. These effects are primarily beneficial for the patient’s vascular system. A significant number of statin users suffer from muscle …

  8. Open Access 06-04-2024 | Statins | Online First

    An Appraisal of the Preventive Effect of Statins on the Development of Graves’ Ophthalmopathy: A Hospital-Based Cohort Study

    Graves’ disease (GD) is the most common cause of hyperthyroidism, with an annual incidence of 20 cases per 100,000 persons and a female to male ratio ranging from 4:1 to 5:1 [ 1 , 2 ]. GD pathogenesis occurs via the stimulation of thyrotropin …

  9. 01-01-2024 | Fluvastatin | News

    Statins

    Muscular disorders
  10. 07-11-2023 | Statins | OriginalPaper

    Statins and new-onset diabetes in primary prevention setting: an updated meta-analysis stratified by baseline diabetes risk

    Statins must be recommended in different populations for their lipid-lowering and anti-inflammatory effects and in this way reduce the associated increased cardiovascular risk [ 1 ]. However, statin intolerance and side effects occur in a minority …

  11. 09-01-2024 | Statins | Online First

    Statins and thyroid eye disease (TED): a systematic review

    GD is an autoimmune disorder in which thyrotropin receptor antibodies (TRAb) stimulate thyroid stimulation hormone (TSH) receptors, resulting in increased production and release of thyroid hormones. The available treatment options include …

  12. 01-01-2024 | Statins | News

    Statins reduce risk of hormone therapy-related VTE

  13. 21-02-2024 | Statins | Online First

    The impact of statins treatments for plaque characteristics in stable angina pectoris patients with very low and high low-density lipoprotein cholesterol levels: an intracoronary optical coherence tomography study

    Low-density lipoprotein cholesterol (LDL-C) levels are recommended according to the patient's risk factors based on guidelines. In patients achieving low LDL-C levels, the need for statins is uncertain, and the plaque characteristics of patients …

  14. 06-11-2023 | Dermatomyositis | OriginalPaper

    Low utilization of statins in patients with dermatomyositis/polymyositis and hyperlipidemia: a multicenter USA-based study (2013–2023)

    Despite the availability of multiple medications for the treatment of hyperlipidemia, HMG-CoA reductase inhibitors, more informally known as statins, remain a first-line therapy [ 1 ]. Statins are highly effective agents that have demonstrated …

  15. Open Access 01-12-2023 | Statins | OriginalPaper

    Statins and cognitive decline in patients with Alzheimer’s and mixed dementia: a longitudinal registry-based cohort study

    The brain houses about a quarter of the cholesterol present in the body, making it the richest cholesterol-containing organ [ 1 ]. The essential role of brain cholesterol is reflected in its involvement in numerous physiological processes such as …

  16. Open Access 01-12-2023 | Statins | OriginalPaper

    Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death

    The many groundbreaking discoveries in molecular immunology and immuno-oncology over the last decades had a tremendous impact on the field of cancer treatment. Since the first immune checkpoint inhibitor (ICI), ipilimumab, was approved by the Food …

  17. Open Access 01-12-2023 | Statins | OriginalPaper

    Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy

    Approximately 95% of all cases of colorectal cancer are adenocarcinomas, and the most common symptoms are abnormal bowel movements and abdominal pain; however, many cases do not have any subjective symptoms, making early detection and treatment …

  18. 05-11-2023 | Simvastatin | OriginalPaper

    Statins abrogate gemcitabine-induced PD-L1 expression in pancreatic cancer-associated fibroblasts and cancer cells with improved therapeutic outcome

    A combination of chemotherapy with immunotherapy has been proposed to have better clinical outcomes in Pancreatic Ductal Adenocarcinoma (PDAC). On the other hand, chemotherapeutics is known to have certain unwanted effects on the tumor …

  19. Open Access 01-12-2023 | Statins | OriginalPaper

    HMGCR gene polymorphism is associated with residual cholesterol risk in premature triple-vessel disease patients treated with moderate-intensity statins

    Studies on atherosclerotic cardiovascular diseases (ASCVD) in China (2021) reported that the burden of ASCVD in the Chinese population is heavy, and the prevalence of ASCVD is keeping rising. It is estimated that the prevalence of ASCVD is 330 …

  20. Open Access 01-12-2023 | Statins | OriginalPaper

    SGLT2 inhibitors can reduce the incidence of abnormal blood glucose caused by statins in non-diabetes patients with HFrEF after PCI

    Despite reductions in the prevalence of cardiovascular risk factors and improvements in therapeutic management, coronary artery disease (CHD) remains one of the leading causes of death worldwide [ 1 – 3 ]. In Europe, cardiovascular disease (CVD) …

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