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Clinical Collections
Women’s Health Knowledge Hub Advances in Alzheimer’s

Navigating neuroimaging in Alzheimer disease care

PET imaging is playing an increasingly critical role in managing AD, but how can you effectively integrate it into clinical practice? Our expert-led program will empower you with practical strategies and real-world case studies.

This content is intended for healthcare professionals outside of the UK.
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Oncology Solid Tumor

Solid Tumor

The evolving treatment landscape of advanced prostate cancer

The advent of PSMA-targeted radioligand therapies and bispecific T-cell engagers has provided new hope for patients with metastatic castration-resistant prostate cancer. Explore the latest evidence.

Read more

Editor's Choice

Reassuring results for ART use in BRCA breast cancer survivors

The use of assisted reproductive technology to conceive after breast cancer in young BRCA1/2 carriers does not appear to worsen disease-free survival or pregnancy outcomes.

A-RT promising for high-risk patients with pancreatic cancer

Ablative radiation therapy can be an alternative option to surgery for the treatment of localized, resectable pancreatic ductal adenocarcinoma, particularly in cases of high surgical risk.

YKL-40 linked to GI cancer risk in type 2 diabetes

Raised YKL-40 levels are associated with an increased risk for obesity-related and gastrointestinal cancers, particularly liver cancer, in people with type 2 diabetes.

Gastric cancer guidelines: exploring international differences

What can we learn from the similarities and differences between gastric cancer guidelines of different countries, and how might this understanding be used to improve patient care?

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Women’s health knowledge hub

Elevate your patient care with our comprehensive, evidence-based medical education on women's health. Designed to help you provide exceptional care for your female patients at every stage of life, we provide expert insights into topics such as reproductive health, menopause, breast cancer and sex-specific health risks and precision medicine.

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Latest News

Reassuring results for ART use in BRCA breast cancer survivors

A-RT promising for high-risk patients with pancreatic cancer

YKL-40 linked to GI cancer risk in type 2 diabetes

Genetic test outplays PSA, MRI for prostate cancer screening

Dual ICIs alongside radiosurgery may increase necrosis risk

Appendiceal tumor rate validated for periappendicular abscess

Incorporating comprehensive genomic profiling into the standard-of-care for NSCLC and thyroid cancer

In this interactive webinar, experts Dr. Subbiah, Dr. Drilon, and Dr. Williams discuss best pathological practices within NSCLC and thyroid cancer, as well as how genomic testing can improve outcomes in clinical practice, using patient case studies as illustrations.

This content is intended only for US-based healthcare providers.

Supported by:
  • Illumina, Inc., and Eli Lilly and Company
Dr. Vivek Subbiah
Dr. Alexander Drilon
Dr. Michelle Williams
Developed by: Springer Healthcare
Watch now
Video

Case Studies

Long-term outcomes after giant cavernous sinus hemangioma

Cavernous sinus hemangiomas are rare vascular tumors characterized by significant intraoperative bleeding which makes management extremely difficult. This case reports the 15 year follow up, without neurological compromise, after successful ligation of the left internal carotid artery during resection. 

Prolactinoma management: a complex path

This case highlights the challenges associated with managing an aggressive macroprolactinoma that's resistant to conventional treatments and explores the use of immunotherapy.

Zolbetuximab-related gastritis

Although gastrointestinal adverse events were not uncommon in trials of the novel agent zolbetuximab, they tended to be transient. This is the first report of delayed-onset and persistent gastritis linked to its use.

At a glance: The DESTINY-Breast trials

The antibody–drug conjugate trastuzumab deruxtecan is being investigated in the DESTINY-Breast trials for the treatment of breast cancer.

Developed by: Springer Medicine
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Current Reviews

Current and future pharmacological therapies for extensive-stage small-cell lung cancer

  • Open Access
  • SCLC
  • short review

Small-cell lung cancer represents a highly aggressive neuroendocrine subtype of lung cancer. In distant metastatic or extensive-stage small-cell lung cancer, the primary treatment approach consists of non-curative pharmacological therapy.

Difficult Decisions in the Multidisciplinary Treatment of Resectable Non-small Cell Lung Cancer

  • NSCLC
  • Thoracic Oncology and Esophageal Cancer

The management of resectable non-small cell lung cancer (NSCLC) has evolved dramatically over the past three decades. Once limited to surgery, treatment strategies now include chemotherapy, immunotherapy, radiation, and targeted therapies. Despite …

MRI radiomics prediction modelling for pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a systematic review and meta-analysis

Colorectal cancer (CRC) is the third commonest malignancy and the second leading cause of cancer mortality in the world [ 1 ]. Rectal cancer represents approximately one third of such CRC patients [ 1 ]. Treatment for locally advanced rectal cancer …

State of the art review of AI in renal imaging

Renal cell carcinoma (RCC) as a significant health concern, with incidence rates rising annually due to increased use of cross-sectional imaging, leading to a higher detection of incidental renal lesions. Differentiation between benign and …

Episode 15: Breastfeeding after breast cancer

POSITIVEly reassuring results from a clinical trial

The POSITIVE trial previously showed that women with breast cancer can safely interrupt endocrine therapy in order to become pregnant. But what about breastfeeding - is that possible and safe for the mother and baby?

Women can take heart from the latest findings, says Dr. Cristina Saura, as she takes us through these important clinical updates.

Dr. Cristina Saura
Listen now
Podcast

CME & eLearning

Webinar

In this interactive webinar, experts discuss best pathological practices within NSCLC and thyroid cancer, as well as how genomic testing can improve outcomes in clinical practice, using patient case studies as illustrations. 

This content is intended only for US-based healthcare providers.

Supported by:
  • Illumina, Inc., and Eli Lilly and Company
Developed by: Springer Healthcare

eLearning | Interviews | Digital Treatment Map | Patient Cases (Link opens in a new window)

0.75 AMA PRA Category 1 Credit(s)™

Expert-led, multiformat program which will address the individualized management of NSCLC, through education on the detection of NTRK gene fusions, current evidence-based guidelines, and new and emerging therapies. Will also include guidance on integrating shared decision making into your clinical practice, drawing on insights from a patient on how best to communicate.

Supported by:
  • Bayer HealthCare Pharmaceuticals Inc.
Developed by: Springer Healthcare IME

eLearning (Link opens in a new window)

The evolving landscape of metastatic urothelial carcinoma brings with it many challenges, such as optimally sequencing therapies and managing adverse events. Navigate your way through these with the Ultimate mUC challenge game and expert-to-expert interviews.

Supported by:
  • Merck Healthcare KGaA, Darmstadt, Germany and Astellas
Developed by: Springer Healthcare IME

Most Viewed in Oncology

Managing bone metastases in gynecologic malignancies

Concerning increase in deaths due to PE in people with cancer

Fecal immunochemical test yields comparable CRC outcomes to colonoscopy screening

Appendiceal tumor rate validated for periappendicular abscess

Detection bias may explain thyroid cancer risk with GLP-1 RA use

Further Reading

Minichromosome maintenance 4 is associated with poor survival and stemness of patients with pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the most well-known cancer types, with a persistently poor 5-year survival rate. We previously reported MCM4 as a molecule associated with cancer stem cells; however, its role in PDAC has not been …

A multicenter randomized open-label phase 2 study investigating optimal antiemetic therapy for patients with advanced/recurrent gastric cancer treated with trastuzumab deruxtecan: the EN-hance study

Gastric cancer (GC) is one of the most common cancers worldwide, causing more than 700,000 deaths annually [ 1 ]. Systemic chemotherapy is the standard treatment for patients with advanced unresectable GC [ 2 , 3 ]. Despite improvements in …

Initial reduction of the primary tumor or lymph nodes: which is the better prognostic factor in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemotherapy followed by surgery?

Esophageal cancer is the seventh most common cancer worldwide [ 1 ]. Neoadjuvant chemotherapy (NAC) plus surgery is the standard treatment strategy for eliminating micrometastases and increasing resectability [ 2 – 5 ]. Recently, a triplet NAC …

Treatment of Primary Solid Renal Tumours Using Histotripsy: Study Protocol for the CAIN Feasibility Trial

Renal cell carcinoma (RCC) accounts for 2% of global cancer diagnoses and deaths, with an estimated 403,000 people diagnosed with neoplasms of the kidney in 2018, according to GLOBOCAN data [ 1 ]. The incidence of renal cancer has more than doubled …

Related topics

Treating seizures in oncology patients

  • Free for a limited time
  • Epilepsy
  • Review

What’s best practice for managing seizures in patients with primary brain tumors or brain metastases, or as a consequence of cancer therapy?

Read more

Updated guidelines for chemotherapy in glioma

CAR T-cell therapy for CNS lymphoma

Key tests for diagnosing pLGG

Advances in treating pLGG

Misdiagnosis of MMNST of the cervical spinal cord

Prolactinoma management: a complex path

This case highlights the challenges associated with managing an aggressive macroprolactinoma that's resistant to conventional treatments and explores the use of immunotherapy.

Read more

Acromegaly and cancer

Pheochromocytoma with heterotaxy syndrome

Evaluating pathologies of the D2 segment of the duodenum

Immune profiling of GH-secreting PitNETs

Detection bias may explain thyroid cancer risk with GLP-1 RA use

A-RT promising for high-risk patients with pancreatic cancer

Ablative radiation therapy can be an alternative option to surgery for the treatment of localized, resectable pancreatic ductal adenocarcinoma, particularly in cases of high surgical risk.

Read more

YKL-40 linked to GI cancer risk in type 2 diabetes

Gastric cancer guidelines: exploring international differences

Do PARP inhibitors have a role in the neoadjuvant setting?

Zolbetuximab-related gastritis

Appendiceal tumor rate validated for periappendicular abscess

The evolving treatment landscape of advanced prostate cancer

The advent of PSMA-targeted radioligand therapies and bispecific T-cell engagers has provided new hope for patients with metastatic castration-resistant prostate cancer. Explore the latest evidence.

Read more

YKL-40 linked to GI cancer risk in type 2 diabetes

Do PARP inhibitors have a role in the neoadjuvant setting?

Genetic test outplays PSA, MRI for prostate cancer screening

Acromegaly and cancer

NeuroSAFE PROOF of improved robotic prostatectomy outcomes

Reassuring results for ART use in BRCA breast cancer survivors

The use of assisted reproductive technology to conceive after breast cancer in young BRCA1/2 carriers does not appear to worsen disease-free survival or pregnancy outcomes.

Read more

Do PARP inhibitors have a role in the neoadjuvant setting?

Managing bone metastases in gynecologic malignancies

Half-dose apixaban for cancer patients at risk for recurrent VTE

Acromegaly and cancer

Novel vaccines for HPV-related cervical cancer

Rare cause of a large hepatic mass

Liver metastasis as the first clinical sign of parotid gland adenoid cystic carcinoma is very rare, but shows that salivary gland tumors should be considered in the differential diagnosis of unexplained hepatic lesions.

Read more

Sugary drinks tied to increased oral cancer risk

De-escalating treatment for HPV-positive oropharyngeal cancer

Targeted therapies for EBV-positive nasopharyngeal cancer

Coffee and tea drinkers may have reduced risk for HNC

Quitting smoking early after cancer diagnosis improves survival

Melanoma risk doubled in childhood cancer survivors

Compared with the general population, childhood cancer survivors have a twofold increased risk for melanoma, with substantially worse survival for those who develop invasive melanoma.

Read more

Emerging therapies for brain metastases

Uncommon type of malignant melanoma

Advances in therapy for non-melanoma skin cancers

Managing the side effects of BRAF and MEK inhibitors

Melanoma in children and young adults

Advances in therapeutic strategies for NSCLC

  • Open Access
  • NSCLC
  • Review

The changing landscape of NSCLC treatment provides numerous novel options, but how can they best be incorporated into clinical practice to improve patient outcomes?

Read more

Half-dose apixaban for cancer patients at risk for recurrent VTE

Radiation-induced lung injury

Advances in targeting MET in NSCLC

  • Open Access
  • NSCLC
  • Review

Can TNF inhibitors be used in RA patients with cancer?

Synchronous breast cancer and pleural mesothelioma

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