Thoracic Cancer

Lung cancer, clinically referred to as primary bronchogenic carcinoma, is a malignant tumor originating from the epithelial cells of the bronchial mucosa or alveolar tissues [ 1 ]. Globally, it poses a highly formidable threat to human health. Lung …

Cisplatin is currently used as the central agent in several cancer chemotherapy protocols because of its broad antitumor spectrum and potent antitumor effects; however, preventing cisplatin-induced renal damage and other adverse events is …

Lung cancer remains the second leading cause of cancer-related morbidity and mortality worldwide, with non-small cell lung cancer (NSCLC) accounting for the majority of cases. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) …

Lung cancer is the leading cause of cancer-related deaths globally, with tumour growth, invasion, and treatment response heavily influenced by the tumour microenvironment (TME). The TME promotes tumour progression by creating an immunosuppressive …

In this concise article, we give a current overview of the practical approach to diagnosing pleural mesothelioma (PM). PM is a rare, incurable, aggressive cancer almost exclusively related to previous asbestos exposure. We begin by outlining the …

The measures comprising Response Evaluation Criteria in Solid Tumors (RECIST) were developed in the context of cytotoxic treatments, with a ≥ 30% reduction in target tumor lesion size from baseline indicating response to treatment [ 1 ]. In the era …

Cigarette smoking is a well-established risk factor for lung cancer [ 1 ], which remains the leading cause of cancer-related mortality worldwide [ 2 – 4 ]. Numerous studies have demonstrated the prognostic impact of smoking status in patients with …

Pleural parenchymal fibroelastosis (PPFE), first reported by Frankel et al. in 2004, is a rare idiopathic interstitial pneumonia characterized by prominent pleural and parenchymal infiltration, mainly in the bilateral upper lobes, and is more …