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Solid Tumor Gastrointestinal Cancer

Gastrointestinal Cancer

Open Access Gastric Cancer Review

International consensus on the management of metastatic gastric cancer

Guidance on the diagnosis, treatment, and care of patients with metastatic gastric cancer, based on the findings of the international multidisciplinary Bertinoro workshop held in November 2022.

Insulinoma misidentified as schizophrenia

Free for a limited time Insulinoma Case Study

Intermittently scanning CGM detected hypoglycemia in a woman previously diagnosed with schizophrenia and treated with antipsychotic medication. Insulinoma was diagnosed and resected, resolving her neuropsychiatric symptoms.

ADCs in cancer: key data for currently approved agents

Open Access Cancer Therapy Review

Delve into the efficacy and safety data for the antibody–drug conjugates currently approved by the US FDA across tumor types such as hematologic, genitourinary, and gynecologic cancers.

Profound hypotension induced by ICI treatment

A case of extreme hypotension that could have been prevented or mitigated with awareness of the underlying hypothyroidism related to nivolumab treatment.

Clinical practice guidelines for esophagogastric junction cancer

Evidence-based recommendations for the diagnosis and treatment of esophagogastric junction cancer, developed at the international Upper GI Oncology Summit 2023.

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Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine

Case Studies

Insulinoma misidentified as schizophrenia

Free for a limited time Insulinoma Case Study

Intermittently scanning CGM detected hypoglycemia in a woman previously diagnosed with schizophrenia and treated with antipsychotic medication. Insulinoma was diagnosed and resected, resolving her neuropsychiatric symptoms.

Profound hypotension induced by ICI treatment

A case of extreme hypotension that could have been prevented or mitigated with awareness of the underlying hypothyroidism related to nivolumab treatment.

An uncommon presentation of CRC

Open Access Colorectal Cancer Case Study

Sciatica due to Streptococcus gallolyticus infection of the spinal epidural space led to a diagnosis of colorectal cancer in a person with none of the usual signs and symptoms.

Current Reviews

Recent updates in the therapeutic uses of Pembrolizumab: a brief narrative review

Hodgkin Lymphoma REVIEW ARTICLE

Cancer is one of the primary public health problems worldwide [ 1 ]. In 2022 it is estimated 19.3 million new cancer cases and 10 million deaths, indicating a significant global burden [ 2 ]. Oncological research is focused in finding new and …

Update on Percutaneous Ablation for Sarcoma

Sarcoma REVIEW

Percutaneous thermal ablation is an important component of the multidisciplinary management of both primary and metastatic sarcomas, providing a minimally invasive alternative or adjunct to surgery and radiation therapy. Although the literature …

Biomarker-oriented chemo-immunotherapy for advanced gastric cancer

Gastric Cancer JSCO Board of Directors Series

The biomarker-oriented chemo-immunotherapy is useful and promising in the development of new anticancer agents, since the responders can be enriched by selecting patients with biomarkers. Compared to colorectal and lung cancers, the development of …

Protein intake and cancer: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society

Open Access Prostate Cancer Review

The global incidence of cancer is on the increase. It is expected that cancer will become the most frequent cause of death in most countries worldwide during the twenty-first century [ 1 , 2 ]. Despite advances in early detection and treatment …

Case-Based Insights: Oncology and Hematology (Link opens in a new window)


Refresh your knowledge in Oncology and Hematology: 

  • 45 clinical cases across different topics with relevant clinical images
  • Written by renowned experts 
  • Knowledge-check questions with answers
Try the first set of cases now

Cases

Take on interactive case studies with a focus on hematology. Each case has been prepared by renowned experts in the field and features knowledge-check questions with answers to help keep you and your practice up to date.

Developed by: Springer Medizin
Webinar | 16-05-2023 | 17:30 (CEST)

Keynote webinar | Spotlight on cardio-oncology

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
Developed by: Springer Medicine

Further Reading

SMARCA4-Deficient Undifferentiated Esophageal Carcinoma: A Clinical Case Series and Literature Review

Open Access Esophageal Cancer Case Report

As of 2020, esophageal cancer (EC) was reported to rank seventh in incidence and sixth in overall mortality among cancers worldwide [ 1 ]. Esophageal squamous cell carcinoma (ESCC) and adenocarcinoma (EAC) are the two main types with 80% of cases …

Interactions between folate metabolism-related nutrients and polymorphisms on colorectal cancer risk: a case-control study in the Basque country

Open Access Colorectal Cancer Original Contribution

Folate-mediated one-carbon metabolism (FOCM) plays an important role in colorectal carcinogenesis. Previous studies have assessed the role of folate-mediated one-carbon metabolism (FOCM)-related gene-diet interaction in the aetiology of colorectal …

Metabolomic Analysis of Human Cirrhosis and Hepatocellular Carcinoma: A Pilot Study

Open Access Hepatocellular Carcinoma Original Article

Hepatocellular carcinoma (HCC) is one of the most lethal malignancies worldwide [ 1 ]. The majority of HCC develops in patients with underlying liver cirrhosis (LC) which provides the opportunity to closely monitor those patients at risk [ 2 , 3 ].