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Bladder Carcinoma 

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  1. Open Access 01-12-2024 | Urothelial Cancer | OriginalPaper

    Diagnostic value of urine cyclic RNA-0071196 for bladder urothelial carcinoma

    Bladder cancer has emerged as a prevalent malignant tumor in the urinary system worldwide. Histologically, bladder urothelial carcinoma (BUC) accounts for approximately 90% of all bladder cancer cases. In 2020, bladder cancer ranked tenth among …

  2. 11-04-2024 | Urothelial Cancer | Online First

    POU2F3-expressing intraepithelial small-cell carcinoma with mixed small-cell carcinoma and conventional-type urothelial carcinoma of the urinary bladder

    Based on lineage-specific transcription factors, small-cell neuroendocrine carcinoma (SmCC) of the urinary bladder has recently been subtyped into three molecular subtypes: ASCL1, NEUROD1 and POU2F3. The latter is a master transcriptional …

  3. Open Access 08-04-2024 | Urothelial Cancer | Online First

    CT and MRI findings of small cell neuroendocrine carcinoma of the urinary bladder: comparison with urothelial carcinoma

    Small cell neuroendocrine carcinoma (SCNEC) is a high-grade tumor of relatively small cells with distinct nuclear characteristics, scant cytoplasm, and neuroendocrine differentiation [ 1 ]. Bladder SCNECs are rare histologic variant that account …

  4. 15-04-2024 | Computed Tomography | Online First

    Prognostic predictive value of urothelial carcinoma of the bladder after TURBT based on multiphase CT radiomics

    Bladder cancer (BCa) is the second most common urologic malignancy worldwide and one of the most prevalent cancers worldwide, with high annual incidence and mortality rates [ 1 ]. Urologists usually stratify patients based on recurrence and …

  5. Open Access 01-12-2024 | Urothelial Cancer | OriginalPaper

    Quantitative differentiation of non-invasive bladder urothelial carcinoma and inverted papilloma based on CT urography

    Bladder tumors are the most prevalent neoplasms of the urinary system, of which epithelial tumors accounting for over 90%, including urothelial carcinoma, low-grade malignant uroepithelial papilloma, adenocarcinoma and squamous cell carcinoma [ 1 …

  6. Open Access 01-12-2024 | Biomarkers | OriginalPaper

    A paclitaxel-hyaluronan conjugate (ONCOFID-P-B™) in patients with BCG-unresponsive carcinoma in situ of the bladder: a dynamic assessment of the tumor microenvironment

    The standard therapy for bladder carcinoma in situ (CIS) is represented by intravesical instillation of Bacillus Calmette-Guerin (BCG) that, however, can lead to intolerance or unresponsiveness [ 1 ].

  7. 24-01-2024 | Cystectomy | OriginalPaper

    Multidisciplinary treatment for small cell carcinoma of the bladder: a case report

    Small cell carcinoma (SCC) of the urinary bladder is a rare and highly aggressive subtype of bladder cancer. Most cases are diagnosed at advanced stages, and its therapeutic strategy remains unestablished. Here, we report a case of bladder SCC in …

  8. Open Access 01-12-2024 | Urothelial Cancer | OriginalPaper

    PD-L1 expression in tumor and inflammatory cells is associated with favorable tumor features and favorable prognosis in muscle-invasive urothelial carcinoma of the bladder not treated by immune checkpoint inhibitors

    Urothelial carcinoma of the urinary bladder belongs to the ten most common malignant cancer types worldwide [ 1 ]. About 80% of patients present with non-invasive low-grade (pTa) or minimally invasive (pT1) stage urothelial bladder carcinomas.

  9. Open Access 06-02-2024 | OriginalPaper

    Primary signet-ring cell carcinoma of the bladder treated with laparoscopic radical cystectomy: a case report

    Primary bladder adenocarcinomas comprise 0.5–2% of all epithelial bladder neoplasms. Of these, primary signet-ring cell carcinoma of the bladder is particularly rare, accounting for 0.24% of all bladder malignancies. This tumor is frequently …

  10. Open Access 18-01-2024 | Urothelial Cancer | BriefCommunication

    [68 Ga]Ga-FAPI-46 PET/CT for locoregional lymph node staging in urothelial carcinoma of the bladder prior to cystectomy: initial experiences from a pilot analysis

    A relevant unmet need in patients with muscle-invasive urothelial carcinoma (UC) of the bladder is the evaluation of the locoregional lymph node status prior to a planned radical cystectomy (RC) as the clinical management and prognosis depend on …

  11. Open Access 01-12-2024 | Urothelial Cancer | OriginalPaper

    Application of contrast-enhanced ultrasound in diagnosis and grading of bladder urothelial carcinoma

    Epithelial bladder tumors are the most common type of urinary system tumors, its incidence rate accounts for about 3% of all cancers [ 1 ]. Bladder urothelial carcinoma (BUC) is the most common malignant epithelial tumor, accounting for …

  12. 01-03-2024 | Urothelial Cancer | OriginalPaper

    Clinical significance of blocking novel immune checkpoint B7-H4 in urothelial carcinoma of bladder as a potential therapeutic target

    Urothelial Carcinoma of Bladder is complex disease with high mortality and recurrence rates. Current standard regimes have exhibited anti-tumor activity but still, a proportion of patients are non-responsive or in-eligible to receive such …

  13. 02-09-2023 | Bladder Carcinoma | OriginalPaper

    MRI-based automated machine learning model for preoperative identification of variant histology in muscle-invasive bladder carcinoma

    Bladder carcinoma is one of the most common and lethal diseases worldwide [ 1 ]. Approximately 25% of patients have muscle-invasive bladder carcinoma (MIBC) at diagnosis [ 2 ]. Neoadjuvant cisplatin-based chemotherapy is the standard treatment for …

  14. Open Access 01-12-2023 | Cystectomy | OriginalPaper

    Pathologic collision of urinary bladder urothelial carcinoma with small cell carcinoma: a case report

    Bladder cancer is the tenth most common cancer in the world, accounting for up to 3% of all new cancer diagnoses [ 1 ]. The incidence of bladder cancer varies with gender, with men having a 3 to 4 times higher morbidity than women [ 2 ]. Previous …

  15. Open Access 01-12-2023 | Magnetic Resonance Imaging | OriginalPaper

    Retroperitoneal urothelial carcinoma arising after bladder diverticulectomy: a case report

    A urinary bladder diverticulum is an out-pouching of the bladder mucosa through a weak bladder muscle, either congenital or acquired, which may be complicated by inflammation, calculus, infection, and malignancy [ 1 ]. If malignancy or inflammation …

  16. Open Access 01-10-2023 | Urothelial Cancer | OriginalPaper

    Loss of Upk1a and Upk1b expression is linked to stage progression in urothelial carcinoma of the bladder

    Urinary bladder cancer is the tenth most common malignant tumor type worldwide [ 1 ]. About 80% of patients present with low-grade non-invasive (pTa) or minimally invasive (pT1) cancers, which are characterized by a good prognosis and can be …

  17. 15-12-2023 | Cystectomy | Online First

    Clinico-demographic Profile of Carcinoma Urinary Bladder—5-Year Experience from a Tertiary Care Centre of Eastern India

    Urinary bladder carcinoma is a disease of the elderly and often presents at an advanced stage due to ignorance and manifestation of symptoms at later stages of the disease. In India, very little data is available regarding the …

  18. Open Access 01-12-2023 | Urothelial Cancer | OriginalPaper

    Comprehensive analysis of cuproptosis-related lncRNAs signature to predict prognosis in bladder urothelial carcinoma

    Bladder urothelial carcinoma (BLCA) is a global health concern and ranks among the top 10 most prevalent types of cancer, with an annual incidence of 550,000 new cases and a mortality rate of 200,000 [ 1 , 2 ]. Among the 80% of patients with …

  19. Open Access 01-12-2023 | Urothelial Cancer | OriginalPaper

    Effect of subsequent bladder cancer on survival in upper tract urothelial carcinoma patients post-radical nephroureterectomy: a systematic review and meta-analysis

    Upper urinary tract urothelial carcinoma (UTUC) is a rare malignant disease that accounts for 5–10% of all urothelial carcinoma [ 1 ]. Radical nephroureterectomy (RNU) with ipsilateral bladder cuff excision (BCE) remains the standard treatment for …

  20. Open Access 01-12-2023 | Urothelial Cancer | OriginalPaper

    Low expression of ZSCAN4 predicts unfavorable outcome in urothelial carcinoma of upper urinary tract and urinary bladder

    Urothelial carcinoma (UC) is the most common epithelial malignancy involving the urinary system. Some environmental factors contribute to increasing risk of UC, including tobacco smoking, intake of arsenic-contaminated water, occupational exposure …

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