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Solid Tumor Gynecologic Cancer

Gynecologic Cancer

Second-line treatment for metastatic TNBC

What is the best second-line treatment option for metastatic triple-negative breast cancer? Discover the latest evidence from clinical trials to answer the question.

Read more

Editor's Choice

Current and future immunotherapy for breast cancer

Explore the recent major clinical trials of immunotherapy in breast cancer and find out more about promising emerging options, such as vaccines, bispecific antibodies, and cellular therapies.

Novel SERD shows promise in advanced breast cancer

Imlunestrant, either alone or alongside abemaciclib, could be an option after progression on endocrine therapy for patients with ER-positive advanced breast cancer.

Manging AF in breast cancer patients

Breast cancer patients have an increased risk of developing atrial fibrillation, due to both the cancer and its treatment, but the underlying mechanisms are still not well understood. What considerations should you make when treating these patients?

Emerging therapies for brain metastases

Therapies designed to penetrate the blood-brain barrier and target key drivers like EGFR, ALK, HER2, and BRAF have revolutionized treatment of brain metastases from non-small-cell lung cancer, breast cancer, and melanoma.

Our tailored content service will keep you up to date…

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Episode 15: Breastfeeding after breast cancer

POSITIVEly reassuring results from a clinical trial

The POSITIVE trial previously showed that women with breast cancer can safely interrupt endocrine therapy in order to become pregnant. But what about breastfeeding - is that possible and safe for the mother and baby?

Women can take heart from the latest findings, says Dr. Cristina Saura, as she takes us through these important clinical updates.

Dr. Cristina Saura
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SPONSORED

Recent advances in the use of CAR T-cell therapies in relapsed/refractory diffuse large B-cell lymphoma and follicular lymphoma

In this webinar, Professor Martin Dreyling and an esteemed international panel of CAR T-cell therapy experts discuss the latest data on the safety, efficacy, and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL.

Please note, this webinar is not intended for healthcare professionals based in the US and UK.

Sponsored by:
  • Novartis Pharma AG
Chaired by: Prof. Martin Dreyling
Developed by: Springer Healthcare
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Case Studies

Vocal cord paralysis caused by metastasized endometrial cancer

The first case of vocal cord paralysis due to a mediastinal metastasis developing 16 years after the patient's endometrial cancer was treated by hysterectomy, external beam radiotherapy, and chemotherapy.

Profound hypotension induced by ICI treatment

A case of extreme hypotension that could have been prevented or mitigated with awareness of the underlying hypothyroidism related to nivolumab treatment.

A rare, late side effect of radiotherapy

A woman developed sudden painless ecchymosis (bruising) of her breast, which was thought to be related to the radiotherapy she received for early-stage breast cancer a year and a half earlier.

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

  • Webinar | 19-02-2024 | 17:30 (CET)

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine
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Current Reviews

Weight Management for Fertility-Preservation Therapy in Endometrial Cancer: Opportunities and Challenges

Endometrial cancer (EC) is the sixth-most common cancer in women, with over 427,000 newly diagnosed cases globally in 2022 [ 1 ]. An increasing number of young patients are choosing to undergo fertility-preservation treatment. The guidelines …

Deep learning-based breast cancer diagnosis in breast MRI: systematic review and meta-analysis

Continuous efforts for early detection and improved treatment are essential in the fight against breast cancer. Recent statistics from the UK Office for National Statistics show a persistently high age-standardized mortality rate for breast cancer …

The prognostic value of the tumor-stroma ratio compared to tumor-infiltrating lymphocytes in triple-negative breast cancer: a review

Previous literature extensively explored biomarkers to personalize treatment for breast cancer patients. The clinical need is especially high in patients with triple-negative breast cancer (TNBC) due to its aggressive nature and limited treatment …

Gene expression profiling tests to guide adjuvant chemotherapy decisions in lymph node-positive early breast cancer: a systematic review

Many patients with hormone receptor-positive (HR+) lymph node-positive (LN+) early stage breast cancer (ESBC) receive adjuvant chemotherapy to reduce the risk of recurrence and improve survival [ 1 ]. However, chemotherapy often has considerable …

Case-based insights: Oncology and hematology (Link opens in a new window)


Refresh your knowledge in oncology and hematology: 

  • 45 clinical cases across different topics with relevant clinical images
  • Written by renowned experts 
  • Knowledge-check questions with answers
Try the first set of cases now

CME & eLearning

Patient Cases

Take on interactive case studies with a focus on hematology. Each case has been prepared by renowned experts in the field and features knowledge-check questions with answers to help keep you and your practice up to date.

Developed by: Springer Medizin

Further Reading

Dynamic Assessment of Local Abdominal Tissue Concentrations of Cisplatin During a HIPEC Procedure: Insights from a Porcine Model

The study was conducted at the Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark. Chemical analyses were performed at the Department of Biochemistry, University Hospital of Southern Jutland, Vejle. The study was approved …

Risk factors for interval breast cancer: insights from a decade of a mammography screening program

Breast cancer is a predominant health concern globally, with steadily rising incidence [ 1 , 2 ]. The widespread adoption of mammography screening programs (MSPs) and technological advancements in treatment options have significantly reduced …

Clinical characteristics and outcomes in leptomeningeal disease with or without brain metastasis: insights from an explorative data analysis of the Charité LMD registry

Leptomeningeal disease (LMD) also known as leptomeningeal metastasis (LMM) involves the spread of cancer cells into the leptomeninges and/or cerebrospinal fluid (CSF). It is generally considered a late-stage complication of metastatic malignancies …

Burden of Disease and Cost of Illness of Triple-Negative Breast Cancer in Portugal

Breast cancer (BC) is the second most common neoplasm globally, accounting for 47.1 new cases per 100,000, or 2,310,051 new cases every year [ 1 ]. It is the leading cause of death among women living with cancer, with 12.7 deaths per 100,000. In …

Related topics

Second-line treatment for metastatic TNBC

What is the best second-line treatment option for metastatic triple-negative breast cancer? Discover the latest evidence from clinical trials to answer the question.

Read more