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73514 search results for:

Cancer Biomarker 

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  1. 14-05-2024 | Online First

    Prostate cancer biomarkers: from early diagnosis to precision treatment

    Prostate cancer (PCa) is the second most prevalent cancer in men. In 2020, approximately 1,414,259 new cases were reported that accounted for 3,75,324 deaths (Sung et al. in CA 71:209–249, 2021). PCa is often asymptomatic at early stages; hence …

  2. Open Access 01-12-2024 | Biomarkers | OriginalPaper

    CXCL10 could be a prognostic and immunological biomarker in bladder cancer

    Immune checkpoint inhibitors (ICIs) have become a crucial component in the treatment of bladder cancer (BLCA). ICIs enhance the ability of T cells to attack tumors by blocking immune inhibitory pathways such as PD-1, PD-L1, or CTLA-4. However, the …

  3. Open Access 01-12-2024 | Adrenocortical Carcinoma | OriginalPaper

    Human pan-cancer analysis of the predictive biomarker for the CDKN3

    Cancer stands as one of the most formidable challenges to global human health [ 1 ]. Despite considerable researches efforts, the intricacies of tumor evolution remain elusive [ 2 ]. Conducting comprehensive pan-cancer analyses, rather than …

  4. Open Access 01-06-2024 | OriginalPaper

    Relationships of emerging biomarkers of cancer cachexia with quality of life, appetite, and cachexia

    Cancer cachexia is defined as a multi-factorial and complex metabolic syndrome [ 1 ] characterized by an ongoing loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support and leads to progressive functional …

  5. Open Access 01-12-2024 | Metastasis | ReviewPaper

    Cancer-derived exosomes as novel biomarkers in metastatic gastrointestinal cancer

    Gastrointestinal cancer (GIC) is the most prevalent and highly metastatic malignant tumor and has a significant impact on mortality rates. Nevertheless, the swift advancement of contemporary technology has not seamlessly aligned with the evolution …

  6. 22-04-2024 | Gastric Cancer | Online First

    Biomarker-oriented chemo-immunotherapy for advanced gastric cancer

    The biomarker-oriented chemo-immunotherapy is useful and promising in the development of new anticancer agents, since the responders can be enriched by selecting patients with biomarkers. Compared to colorectal and lung cancers, the development of …

  7. 14-05-2024 | Online First

    Measuring cfDNA integrity as a biomarker for predicting neoadjuvant chemotherapy response in breast cancer patients: a pilot study

    Breast Cancer (BC) is responsible for about 11.7% of cancer incidence reaching almost 700.000 deaths [ 1 ]. About 40% of BC patients present with axillary involvement at diagnosis some of which will require neoadjuvant chemotherapy (NAC) as a part …

  8. 25-04-2024 | Pancreatic Cancer | Online First

    The role of biomarkers in the early detection of pancreatic cancer

    Pancreatic surveillance can detect early-stage pancreatic cancer and achieve long-term survival, but currently involves annual endoscopic ultrasound and MRI/MRCP, and is recommended only for individuals who meet familial/genetic risk criteria. To …

  9. Open Access 01-12-2024 | Prostate Cancer | OriginalPaper

    Endoplasmic reticulum stress-related genes as prognostic and immunogenic biomarkers in prostate cancer

    Prostate cancer (PCa) has become one of the major malignant tumors that threatens men’s health and survival due to its aggressive metastasis [ 1 ]. Previous clinical studies suggest that PCa advances to castration-resistant prostate cancer (CRPC) …

  10. Open Access 01-12-2024 | Breast Cancer | OriginalPaper

    Remnant cholesterol is an effective biomarker for predicting survival in patients with breast cancer

    Breast cancer is the most common malignant tumour in women, and its case fatality rate ranks second among women tumours, posing a major threat to women’s health and quality of life [ 1 ]. Despite remarkable advances in preventing, diagnosing, and …

  11. Open Access 01-12-2024 | Gastric Cancer | OriginalPaper

    Biomarkers of lipid metabolism in gastric cancer: a case control study

    Gastric cancer is a common malignant tumor. In the global malignant tumors, the incidence of gastric cancer ranks sixth and the mortality rate ranks the third [ 1 ] . It has high incidence in east Asia, especially in China, the incidence and …

  12. 04-05-2024 | Choroidal Melanoma | Online First

    The cuproptosis-related gene UBE2D2 functions as an immunotherapeutic and prognostic biomarker in pan-cancer

    Cancer is a leading cause of death across the world. Newly diagnosed cancer cases and cancer-related deaths are increasing dramatically, becoming a major burden for many nations [ 1 ]. Cuproptosis is a recently identified form of cell death [ 2 ].

  13. Open Access 01-12-2024 | OriginalPaper

    The S100 family is a prognostic biomarker and correlated with immune cell infiltration in pan-cancer

    In the context of tumor progression, conventional understanding has primarily focused on genetic and epigenetic alterations within tumor cells as the primary drivers. However, recent research has increasingly highlighted the vital role of the …

  14. 02-04-2024 | Biomarkers | BriefCommunication

    ASO Author Reflections: Vasohibin-1 as a Biomarker for Chemotherapeutic Response in Patients with Advanced Bladder Cancer

    Patients with muscle-invasive bladder cancer (MIBC) are known to have an aggressive clinical course, and neoadjuvant chemotherapy (NAC) is currently established as part of standard treatment. However, patients with poor response to NAC are bound …

  15. Open Access 01-12-2024 | Cervical Cancer | OriginalPaper

    High-throughput metabolomics identifies new biomarkers for cervical cancer

    Cervical cancer (CC) is an important global public health issue, which ranks as one of the most common cancers and the top leading cause of cancer death in middle-aged women [ 1 , 2 ]. CC has multiple risk factors including high-risk human …

  16. Open Access 01-12-2024 | Anxiety | OriginalPaper

    The associates of anxiety among lung cancer patients: Dehydroepiandrosterone (DHEA) as a potential biomarker

  17. 27-01-2024 | Prostate Cancer | OriginalPaper

    The association between methylmalonic acid, a biomarker of mitochondrial dysfunction, and risk of prostate cancer

    Prostate cancer (PCa) is a disease that is both heterogenous and has a high incidence. It is the second most common cancer for males and the fifth leading cause of cancer death [ 1 ]. A global cancer burden report states that between 2018 and 2020 …

  18. Open Access 09-05-2024 | Cytostatic Therapy | Online First

    Long-term prospective outcome data using EndoPredict as risk stratification and chemotherapy decision biomarker in hormone receptor-positive, HER2-negative early breast cancer

    Endocrine therapy is the mainstay treatment for patients with hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative, early breast cancer. Although endocrine therapy has been shown to reduce the risk of recurrence and …

  19. Open Access 01-12-2024 | Biomarkers | ReviewPaper

    Decoding the glycoproteome: a new frontier for biomarker discovery in cancer

    Cancer early detection and treatment response prediction continue to pose significant challenges. Cancer liquid biopsies focusing on detecting circulating tumor cells (CTCs) and DNA (ctDNA) have shown enormous potential due to their non-invasive …

  20. Open Access 01-12-2024 | Sevoflurane | OriginalPaper

    Lidocaine effects on neutrophil extracellular trapping and angiogenesis biomarkers in postoperative breast cancer patients with different anesthesia methods: a prospective, randomized trial

    Cancer, a global health challenge, ranks as the leading or second-leading cause of death worldwide and holds the top position in China. Notably, female breast cancer has surpassed lung cancer as the most frequently diagnosed cancer globally and …

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