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Solid Tumor Genitourinary Cancer

Genitourinary Cancer

Belzutifan outperforms everolimus in advanced RCC

Treatment with belzutifan achieves significantly better outcomes than everolimus in heavily pretreated patients with stage IV renal cell carcinoma.

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Editor's Choice

Practical approach to managing apalutamide-related rash

Skin rash is a common side effect of apalutamide, and even low-grade events can lead to dose reductions and discontinuation. Use this practical guidance for early identification and management to help your patients stay on treatment.

Advances in the management of mCRPC

What are the latest advances in the ever-expanding list of treatment options for metastatic castration-resistant prostate cancer? And how can you best integrate these agents into your clinical practice?

Arrhythmia secondary to abiraterone treatment

A man receiving abiraterone for prostate cancer developed severe hypokalemia, which led to polymorphic ventricular tachycardia and cardiac arrest. It is important to consider iatrogenic causes in cases of arrhythmia.

Postoperative pembrolizumab improves OS in high-risk RCC

Adjuvant treatment with pembrolizumab is associated with a significant overall survival benefit in individuals with high-risk renal cell carcinoma.

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Keynote webinar | Spotlight on antibody–drug conjugates in cancer

  • Webinar | 19-02-2024 | 17:30 (CET)

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine
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SPONSORED

Recent advances in the use of CAR T-cell therapies in relapsed/refractory diffuse large B-cell lymphoma and follicular lymphoma

  • Live
  • Webinar | 01-10-2024 | 12:30 (CEST)

Live: Tuesday 1st October 2024, 12:30-14:00 (CEST)

In this webinar, Professor Martin Dreyling and an esteemed international panel of CAR T-cell therapy experts discuss the latest data on the safety, efficacy, and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL.

Please note, this webinar is not intended for healthcare professionals based in the US and UK.

Sponsored by:
  • Novartis Pharma AG
Chaired by: Prof. Martin Dreyling
Developed by: Springer Healthcare
Reserve your place now

Case Studies

Arrhythmia secondary to abiraterone treatment

A man receiving abiraterone for prostate cancer developed severe hypokalemia, which led to polymorphic ventricular tachycardia and cardiac arrest. It is important to consider iatrogenic causes in cases of arrhythmia.

Lung erosion following adjuvant immunotherapy

Adjuvant pembrolizumab treatment after resection of lung metastases in a patient with renal cell carcinoma may have led to lung erosion that resulted in a pneumothorax.

Progressive encephalomyelitis with rigidity and myoclonus (PERM) associated with urothelial carcinoma

The first reported case of PERM associated with anti-glycine receptor antibodies in a patient with bladder cancer. PERM, a stiff-person syndrome, has paraneoplastic etiology in about 20% of cases.

Case-based insights: Oncology and hematology (Link opens in a new window)


Refresh your knowledge in oncology and hematology: 

  • 45 clinical cases across different topics with relevant clinical images
  • Written by renowned experts 
  • Knowledge-check questions with answers
Try the first set of cases now

Current Reviews

Imaging assessment of prostate cancer recurrence: advances in detection of local and systemic relapse

Prostate cancer (PCa) relapse, defined either by persistent PSA levels (after RP) or biochemical recurrence (BCR), is a common occurrence. The imaging evaluation of patients experiencing PCa relapse has undergone significant advancements in the …

Hereditary renal mass syndromes: a pictorial review

Hereditary renal mass syndromes, although rare, account for at least 3–5% of kidney cancers and significantly impact affected families. Accurate diagnosis and management by radiologists are crucial as these syndromes often present at imaging with …

PSMA PET/CT imaging and its application to prostate cancer treatment

Recognition of the importance of prostate-specific membrane antigen (PSMA) PET/CT in the diagnosis of prostate cancer has steadily increased following the publication of extensive data on its diagnostic accuracy and impact on patient management …

Differences in the risk of immune-related pneumonitis between PD-1 and PD-L1 inhibitors: a meta-analysis according to the new mirror-principle and PRISMA guidelines

Many clinical trials have confirmed that programmed death-1 (PD-1) or Programmed cell death ligand 1 (PD-L1) inhibitors have excellent clinical efficacy for malignant tumors [ 1 – 87 ]. Due to their unique immune mechanism, many immune-related side …

Keynote webinar | Spotlight on cardio-oncology

  • Webinar | 16-05-2023 | 17:30 (CEST)

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
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CME & eLearning

eLearning (Link opens in a new window)

The evolving landscape of metastatic urothelial carcinoma brings with it many challenges, such as optimally sequencing therapies and managing adverse events. Navigate your way through these with the Ultimate mUC challenge game and expert-to-expert interviews.

Supported by:
  • Merck Healthcare KGaA, Darmstadt, Germany and Astellas
Developed by: Springer Healthcare IME

eLearning | Interviews | Cases (Link opens in a new window)

Multiformat program highlighting evidence-based best practice for the management of metastatic urothelial carcinoma.

Supported by:
  • Pfizer and Merck Healthcare KGaA, Darmstadt, Germany
Developed by: Springer Healthcare IME

Further Reading

New histological risk grading system for prediction of lymph node metastasis in patients with penile cancer

Inguinal lymph node surgery is a standard treatment for penile cancer patients with intermediate or high risk for lymph node metastasis (LNM) according to European Association of Urology (EAU) risk grading. We are proposing a more objective …

Prostate-specific antigen testing patterns and prostate cancer stage at diagnosis in older Ohio cancer patients

Prostate cancer (PCa) is the second most common cancer among the United States men [ 1 ]. Although the incidence of PCa has remained stable over the past decade, the percentage of PCa cases diagnosed at a distant stage has increased from 3.9 to …

PSMA PET/CT imaging and its application to prostate cancer treatment

Recognition of the importance of prostate-specific membrane antigen (PSMA) PET/CT in the diagnosis of prostate cancer has steadily increased following the publication of extensive data on its diagnostic accuracy and impact on patient management …

Efficacy and safety of rechallenge with [177Lu]Lu-PSMA-I&T radioligand therapy in metastatic castration resistant prostate cancer

Prostate cancer (PCa) is the second most common cancer in men, with an estimated 1.4 million diagnoses and 397,000 deaths worldwide in 2022. In Europe, it is the most commonly diagnosed cancer and the third leading cancer-related cause of death [ 1 …].