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Solid Tumor Skin Cancer

Skin Cancer

Subepithelial lesions of the ocular surface

Differentiating subconjunctival lesions can be challenging even among experienced clinicians. Discover how to diagnose and manage conjunctival melanoma, lymphoma, myxoma, neuroma, and amyloidosis, and benign reactive lymphoid hyperplasia.

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Editor's Choice

What's new in Merkel cell carcinoma

Merkel cell carcinoma is a rare, aggressive cutaneous neuroendocrine carcinoma. Learn about the diagnostic workup, prognostic markers, current treatments, and emerging targets.

How to treat metastatic uveal melanoma in 2025

Uveal melanoma is the most common intraocular malignancy in adults, representing a rare but aggressive subtype. Get up to date with the latest options for treating patients with metastatic disease.

Melanoma risk doubled in childhood cancer survivors

Compared with the general population, childhood cancer survivors have a twofold increased risk for melanoma, with substantially worse survival for those who develop invasive melanoma.

Emerging therapies for brain metastases

Therapies designed to penetrate the blood-brain barrier and target key drivers like EGFR, ALK, HER2, and BRAF have revolutionized treatment of brain metastases from non-small-cell lung cancer, breast cancer, and melanoma.

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Keynote webinar | Spotlight on antibody–drug conjugates in cancer

  • On-demand Webinar

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine
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SPONSORED

Recent advances in the use of CAR T-cell therapies in relapsed/refractory diffuse large B-cell lymphoma and follicular lymphoma

In this webinar, Professor Martin Dreyling and an esteemed international panel of CAR T-cell therapy experts discuss the latest data on the safety, efficacy, and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL.

Please note, this webinar is not intended for healthcare professionals based in the US and UK.

Sponsored by:
  • Novartis Pharma AG
Chaired by: Prof. Martin Dreyling
Developed by: Springer Health+
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Case Studies

Uncommon type of malignant melanoma

The amelanotic variant of conjunctival malignant melanoma is extremely rare and can be difficult to diagnose. Clinicians must be vigilant when changes in the conjunctiva and eyelids are noticed.

Oncolytic virus therapy promising in mucosal melanoma

Intralesional treatment with the oncolytic virus talimogene laherparepvec led to a complete local response in a patient with oral mucosal melanoma who was ineligible for other anticancer therapies.

A challenging diagnosis: melanoma or clear cell sarcoma?

A case of clear cell sarcoma of soft tissue misdiagnosed as malignant melanoma underscores the need for an integrated diagnostic approach involving clinical, histopathological, and radiological evaluations.

Case-based insights: Oncology and hematology (Link opens in a new window)


Refresh your knowledge in oncology and hematology: 

  • 45 clinical cases across different topics with relevant clinical images
  • Written by renowned experts 
  • Knowledge-check questions with answers
Try the first set of cases now

Current Reviews

The Role of Cetuximab in Non-Melanoma Skin Cancer: A Review of Clinical Evidence and Emerging Strategies

Non-melanoma skin cancers (NMSCs), particularly basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), are the most common malignancies in the Caucasian population. While localized disease has a high cure rate, advanced cases …

A Comprehensive Narrative Review of the Challenges Surrounding Cutaneous SCC

Cutaneous squamous cell carcinoma (cSCC) is the second most common nonmelanoma skin cancer (NMSC) and is predominantly found in the head and neck region. With an annual increase in NMSC diagnoses, cSCC presents significant diagnostic and …

Tumor-Infiltrating Lymphocyte Therapy for the Treatment of Metastatic Melanoma

Tumor-infiltrating lymphocyte (TIL) therapy is a type of personalized immunotherapy that harnesses the antitumor activity of endogenous immune cells. While TIL therapy has been in clinical investigation since the 1980s and shown promising signs of …

Epidermal radionuclide therapy with 188rhenium—the new treatment for skin squamous cell carcinoma

Nonmelanoma skin cancer (NMSC), including basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), is the most common form of skin cancer. cSCC can usually be cured if detected and treated early. Prompt treatment is essential, as …

Keynote webinar | Spotlight on cardio-oncology

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
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CME & eLearning

Patient Cases

Take on interactive case studies with a focus on hematology. Each case has been prepared by renowned experts in the field and features knowledge-check questions with answers to help keep you and your practice up to date.

Developed by: Springer Medizin

Further Reading

A Comparative Analysis Dissecting the Immune Landscape of Vitiligo and Melanoma from a single-cell Perspective: Two Sides of the Same Coin?

Vitiligo, a prevalent depigmenting disorder, is characterized by the focal loss of melanocytes within the epidermis, leading to the formation of characteristic white patches [ 1 ]. The progression of vitiligo is influenced by a complex interplay of …

Cancer therapy via neoepitope-specific monoclonal antibody cocktails

Cellular heterogeneity presents a significant challenge to cancer treatment. Antibody therapies targeting individual tumor-associated antigens can be extremely effective but are not suited for all patients and often fail against tumors with …

Integration of immunotherapy and radiotherapy in a therapeutic algorithm for locally advanced squamous cell skin cancer

Locally advanced squamous cell skin cancer (LA-sqCSC) affects older patients who initially decline medical assistance and patients after multiple surgical interventions for recurrent tumors. Radical radiotherapy (RT) often becomes difficult to …

Real-World Outcomes of Pembrolizumab in Advanced Melanoma by Age and Sex: A National Population-Based Study

  • Open Access
  • Melanoma
  • Original Research

Melanoma accounts for 1.7% of all global cancer diagnoses [ 1 ], with Australia and New Zealand having some of the highest incidence rates (age-standardized rate of 35.8 per 100,000 persons) [ 2 ]. Prognosis for cutaneous melanoma heavily depends …