Issue 1/2019
Content (293 Articles)
Galectin-3 enhances monocyte-derived macrophage efferocytosis of apoptotic granulocytes in asthma
Melanie Erriah, Kavita Pabreja, Michael Fricker, Katherine J. Baines, Louise E. Donnelly, Johan Bylund, Anna Karlsson, Jodie L. Simpson
A retinoid X receptor partial agonist attenuates pulmonary emphysema and airway inflammation
Daisuke Morichika, Nobuaki Miyahara, Utako Fujii, Akihiko Taniguchi, Naohiro Oda, Satoru Senoo, Mikio Kataoka, Mitsune Tanimoto, Hiroki Kakuta, Katsuyuki Kiura, Yoshinobu Maeda, Arihiko Kanehiro
Circular RNAs: a rising star in respiratory diseases
Jian Wang, Mengchan Zhu, Jue Pan, Cuicui Chen, Shijin Xia, Yuanlin Song
Treatment response to indacaterol/glycopyrronium versus salmeterol/fluticasone in exacerbating COPD patients by gender: a post-hoc analysis in the FLAME study
Jadwiga A. Wedzicha, Dave Singh, Ioanna Tsiligianni, Christine Jenkins, Sebastian Fucile, Robert Fogel, Steven Shen, Pankaj Goyal, Karen Mezzi, Konstantinos Kostikas
Do sputum or circulating blood samples reflect the pulmonary transcriptomic differences of COPD patients? A multi-tissue transcriptomic network META-analysis
Rosa Faner, Jarrett D. Morrow, Sandra Casas-Recasens, Suzanne M. Cloonan, Guillaume Noell, Alejandra López-Giraldo, Ruth Tal-Singer, Bruce E. Miller, Edwin K. Silverman, Alvar Agustí, Craig P. Hersh
Gasometric gradients between blood obtained from the pulmonary artery wedge and pulmonary artery positions in pulmonary arterial hypertension
Ghaleb Khirfan, Mostafa K. Ahmed, Michael D. Faulx, Wael Dakkak, Raed A. Dweik, Adriano R. Tonelli
Breath biomarkers in idiopathic pulmonary fibrosis: a systematic review
Conal Hayton, Dayle Terrington, Andrew M. Wilson, Nazia Chaudhuri, Colm Leonard, Stephen J. Fowler
Exhaled particles and small airways
B. Bake, P. Larsson, G. Ljungkvist, E. Ljungström, A-C Olin
Phospholipase Cε plays a crucial role in neutrophilic inflammation accompanying acute lung injury through augmentation of CXC chemokine production from alveolar epithelial cells
Kanoko Umezawa, Tatsuya Nagano, Kazuyuki Kobayashi, Ryota Dokuni, Masahiro Katsurada, Masatsugu Yamamoto, Yoko Yoshikawa, Tohru Kataoka, Yoshihiro Nishimura
Absence of early metabolic response assessed by 18F-FDG PET/CT after initiation of antifibrotic drugs in IPF patients
Benjamin Bondue, Amélie Castiaux, Gaetan Van Simaeys, Céline Mathey, Félicie Sherer, Dominique Egrise, Simon Lacroix, François Huaux, Gilles Doumont, Serge Goldman
Loss of the adhesion G-protein coupled receptor ADGRF5 in mice induces airway inflammation and the expression of CCL2 in lung endothelial cells
Fumimasa Kubo, Donna Maretta Ariestanti, Souta Oki, Taku Fukuzawa, Ryotaro Demizu, Tomoya Sato, Rahmaningsih Mara Sabirin, Shigehisa Hirose, Nobuhiro Nakamura
Continuous exercise induces airway epithelium damage while a matched-intensity and volume intermittent exercise does not
Adrien Combes, Jeanne Dekerle, Xavier Dumont, Rosie Twomey, Alfred Bernard, Frédéric Daussin, Valérie Bougault
Interstitial lung disease associated with systemic sclerosis (SSc-ILD)
Vincent Cottin, Kevin K. Brown
Modulation of blood inflammatory markers by benralizumab in patients with eosinophilic airway diseases
Sriram Sridhar, Hao Liu, Tuyet-Hang Pham, Gautam Damera, Paul Newbold
Whole blood RNA sequencing reveals a unique transcriptomic profile in patients with ARDS following hematopoietic stem cell transplantation
Joshua A. Englert, Michael H. Cho, Andrew E. Lamb, Maya Shumyatcher, Diana Barragan-Bradford, Maria C. Basil, Angelica Higuera, Colleen Isabelle, Mayra Pinilla Vera, Paul B. Dieffenbach, Laura E. Fredenburgh, Joyce B. Kang, Ami S. Bhatt, Joseph H. Antin, Vincent T. Ho, Robert J. Soiffer, Judie A. Howrylak, Blanca E. Himes, Rebecca M. Baron
Effect of pirfenidone on lung function decline and survival: 5-yr experience from a real-life IPF cohort from the Czech EMPIRE registry
Monika Zurkova, Eva Kriegova, Vitezslav Kolek, Vladimira Lostakova, Martina Sterclova, Vladimir Bartos, Martina Doubkova, Ilona Binkova, Michal Svoboda, Jana Strenkova, Marketa Janotova, Martina Plackova, Ladislav Lacina, Vladimir Rihak, Frantisek Petrik, Pavlina Lisa, Radka Bittenglova, Richard Tyl, Gustav Ondrejka, Hana Suldova, Jaroslav Lnenicka, Jana Psikalova, Tomas Snizek, Jiri Homolka, Renata Kralova, Jan Kervitzer, Martina Vasakova
Effectiveness of long-term using statins in COPD – a network meta-analysis
Yongbin Lu, Ruixia Chang, Jia Yao, Xinni Xu, Yongjun Teng, Ning Cheng
Correction to: Cost-effectiveness analysis of umeclidinium bromide/vilanterol 62.5/25 mcg versus tiotropium/olodaterol 5/5 mcg in symptomatic patients with chronic obstructive pulmonary disease: a Spanish National Healthcare System perspective
M. T. Driessen, J. Whalen, B. Seewoodharry Buguth, L. A. Vallejo-Aparicio, I. P. Naya, Y. Asukai, B. Alcázar-Navarrete, M. Miravitlles, F. García-Río, N. A. Risebrough
Association of plasma soluble CD14 level with asthma severity in adults: a case control study in China
Ting Zhou, Xiji Huang, Jixuan Ma, Yun Zhou, Yuewei Liu, Lili Xiao, Jing Yuan, Jungang Xie, Weihong Chen
NLRP3 deletion inhibits inflammation-driven mouse lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide
Li Huang, Shuyin Duan, Hua Shao, Aihua Zhang, Shuang Chen, Peng Zhang, Na Wang, Wei Wang, Yongjun Wu, Jing Wang, Hong Liu, Wu Yao, Qiao Zhang, Feifei Feng
Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of dams (female mice)
Jordan Smoothy, Alexander N. Larcombe, Emily K. Chivers, Vance B. Matthews, Shelley Gorman
Scored minor criteria for severe community-acquired pneumonia predicted better
Qi Guo, Wei-dong Song, Hai-yan Li, Yi-ping Zhou, Ming Li, Xiao-ke Chen, Hui Liu, Hong-lin Peng, Hai-qiong Yu, Xia Chen, Nian Liu, Zhong-dong Lü, Li-hua Liang, Qing-zhou Zhao, Mei Jiang
Clinical role, safety and diagnostic accuracy of percutaneous transthoracic needle biopsy in the evaluation of pulmonary consolidation
Nantaka Kiranantawat, Shaunagh McDermott, Florian J. Fintelmann, Sydney B. Montesi, Melissa C. Price, Subba R. Digumarthy, Amita Sharma
Transcriptome analysis reveals the role of the PCP pathway in fipronil and endotoxin-induced lung damage
Arif Ahmad Pandit, Ravi Kumar Gandham, C. S. Mukhopadhyay, Ramneek Verma, R. S. Sethi
Handover of the Editor in Chief positions – from the new Editors-in-Chief to the readership of Respiratory Research
Kelan Tantisira, Oliver Schildgen
BAMBI regulates macrophages inducing the differentiation of Treg through the TGF-β pathway in chronic obstructive pulmonary disease
Sheng-Wen Sun, Long Chen, Mei Zhou, Jiang-Hua Wu, Zhao-Ji Meng, Hong-Li Han, Shuai-Ying Miao, Chen-Chen Zhu, Xian-Zhi Xiong
Ethyl pyruvate reduces organic dust-induced airway inflammation by targeting HMGB1-RAGE signaling
Sanjana Mahadev Bhat, Nyzil Massey, Locke A. Karriker, Baljit Singh, Chandrashekhar Charavaryamath
Porcine vs bovine surfactant therapy for preterm neonates with RDS: systematic review with biological plausibility and pragmatic meta-analysis of respiratory outcomes
Ascanio Tridente, Lucia De Martino, Daniele De Luca
What links ventilator driving pressure with survival in the acute respiratory distress syndrome? A computational study
Anup Das, Luigi Camporota, Jonathan G. Hardman, Declan G. Bates
Effect of COPD severity and comorbidities on the result of the PHQ-9 tool for the diagnosis of depression: results from the COSYCONET cohort study
Sarah Marietta von Siemens, Rudolf A. Jörres, Jürgen Behr, Peter Alter, Johanna Lutter, Tanja Lucke, Sandra Söhler, Tobias Welte, Henrik Watz, Claus F. Vogelmeier, Franziska Trudzinski, Winfried Rief, Britta Herbig, Kathrin Kahnert
Desmin and dystrophin abnormalities in upper airway muscles of snorers and patients with sleep apnea
Farhan Shah, Karl A. Franklin, Thorbjörn Holmlund, Eva Levring Jäghagen, Diana Berggren, Sture Forsgren, Per Stål
Is cellular senescence involved in cystic fibrosis?
Valentino Bezzerri, Francesco Piacenza, Nicole Caporelli, Marco Malavolta, Mauro Provinciali, Marco Cipolli
Second-hand smoke exposure in adulthood and lower respiratory health during 20 year follow up in the European Community Respiratory Health Survey
Claudia Flexeder, Jan-Paul Zock, Deborah Jarvis, Giuseppe Verlato, Mario Olivieri, Geza Benke, Michael J. Abramson, Torben Sigsgaard, Cecilie Svanes, Kjell Torén, Dennis Nowak, Rain Jõgi, Jesús Martinez-Moratalla, Pascal Demoly, Christer Janson, Thorarinn Gislason, Roberto Bono, Mathias Holm, Karl A. Franklin, Judith Garcia-Aymerich, Valérie Siroux, Bénédicte Leynaert, Sandra Dorado Arenas, Angelo Guido Corsico, Antonio Pereira-Vega, Nicole Probst-Hensch, Isabel Urrutia Landa, Holger Schulz, Joachim Heinrich
Persistent exercise limitation after successful pulmonary endoarterectomy: frequency and determinants
Angelo G. Corsico, Andrea M. D’Armini, Valentina Conio, Antonio Sciortino, Maurizio Pin, Valentina Grazioli, Giulia Di Vincenzo, Rita Di Domenica, Anna Celentano, Benedetta Vanini, Amelia Grosso, Erica Gini, Federica Albicini, Vera N. Merli, Vanessa Ronzoni, Stefano Ghio, Catherine Klersy, Isa Cerveri
Thoracic skeletal muscle quantification: low muscle mass is related with worse prognosis in idiopathic pulmonary fibrosis patients
Sung Woo Moon, Ji Soo Choi, Sang Hoon Lee, Kyung Soo Jung, Ji Ye Jung, Young Ae Kang, Moo Suk Park, Young Sam Kim, Joon Chang, Song Yee Kim
Identification of differentially expressed proteins in the injured lung from zinc chloride smoke inhalation based on proteomics analysis
Xiaowei Xie, Jingan Zhao, Lixin Xie, Haiyan Wang, Yan Xiao, Yingjia She, Lingyun Ma
Efficacy and safety of AZD7594, an inhaled non-steroidal selective glucocorticoid receptor modulator, in patients with asthma: a phase 2a randomized, double blind, placebo-controlled crossover trial
Mary N. Brown, Rainard Fuhr, Jutta Beier, Hong-Lin Su, Yingxue Chen, Henrik Forsman, Ulrika Wählby Hamrén, Helen Jackson, Ajay Aggarwal
Association between ADAM33 polymorphisms and asthma risk: a systematic review and meta-analysis
Hui-fang Li, Li-ping Yan, Kun Wang, Xiao-tong Li, Hai-xian Liu, Wei Tan
An evaluation of the effects of saffron supplementation on the asthma clinical symptoms and asthma severity in patients with mild and moderate persistent allergic asthma: a double-blind, randomized placebo-controlled trial
Marzie Zilaee, Seyed Ahmad Hosseini, Sima Jafarirad, Farhad Abolnezhadian, Bahman Cheraghian, Foroogh Namjoyan, Ataollah Ghadiri
Use of Berlin questionnaire in comparison to polysomnography and home sleep study in patients with obstructive sleep apnea
Susanna S. Ng, Wilson Tam, Tat-On Chan, Kin-Wang To, Jenny Ngai, Ken K. P. Chan, Wing-Ho Yip, Rachel L. Lo, Karen Yiu, Fanny W. Ko, David S. Hui
Comparison of therapeutic effects of inhaled corticosteroids on three subtypes of cough variant asthma as classified by the impulse oscillometry system
Hiroyuki Sugawara, Atsushi Saito, Saori Yokoyama, Kazunori Tsunematsu, Hiroki Takahashi
Pulmonary arterial remodelling by deficiency of peroxisome proliferator-activated receptor-γ in murine vascular smooth muscle cells occurs independently of obesity-related pulmonary hypertension
Evren Caglayan, Manuela Trappiel, Arnica Behringer, Eva Maria Berghausen, Margarete Odenthal, Ernst Wellnhofer, Kai Kappert
Prognostic impact of residual SYNTAX score in patients with obstructive sleep apnea and acute coronary syndrome: a prospective cohort study
Yaping Zeng, Shuhan Yang, Xiao Wang, Jingyao Fan, Shaoping Nie, Yongxiang Wei
Extent, trends, and determinants of controller/reliever balance in mild asthma: a 14-year population-based study
Amir Khakban, J. Mark FitzGerald, Hamid Tavakoli, Larry Lynd, Solmaz Ehteshami-Afshar, Mohsen Sadatsafavi
Regional lung densities in alpha-1 antitrypsin deficiency compared to predicted values
Berend C. Stoel, Jan Stolk, M. Els Bakker, David G. Parr
The composition of the pulmonary microbiota in sarcoidosis – an observational study
André Becker, Giovanna Vella, Valentina Galata, Katharina Rentz, Christoph Beisswenger, Christian Herr, Jörn Walter, Sascha Tierling, Hortense Slevogt, Andreas Keller, Robert Bals
Psychometric properties and minimal important differences of SF-36 in Idiopathic Pulmonary Fibrosis
Sabine Witt, Ekaterina Krauss, María Asunción Nieto Barbero, Veronika Müller, Philippe Bonniaud, Carlo Vancheri, Athol U. Wells, Martina Vasakova, Alberto Pesci, Walter Klepetko, Werner Seeger, Bruno Crestani, Reiner Leidl, Rolf Holle, Larissa Schwarzkopf, Andreas Guenther
Down-regulation of microRNA-144-3p and its clinical value in non-small cell lung cancer: a comprehensive analysis based on microarray, miRNA-sequencing, and quantitative real-time PCR data
Yu-Ji Chen, Yi-Nan Guo, Ke Shi, Hui-Mei Huang, Shu-Ping Huang, Wen-Qing Xu, Zu-Yun Li, Kang-Lai Wei, Ting-Qing Gan, Gang Chen
The pathology of small airways disease in COPD: historical aspects and future directions
Andrew Higham, Anne Marie Quinn, José Eduardo D. Cançado, Dave Singh
Prognostic value of serum macrophage migration inhibitory factor levels in pulmonary tuberculosis
Qingjiang Wang, Wei Han, Junmei Niu, Bing Sun, Wei Dong, Guangpeng Li
Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust
Kristi J. Warren, John D. Dickinson, Amy J. Nelson, Todd A. Wyatt, Debra J. Romberger, Jill A. Poole
Role of RASEF hypermethylation in cigarette smoke-induced pulmonary arterial smooth muscle remodeling
Qinghai Li, Jixing Wu, Yongjian Xu, Lu Liu, Jungang Xie
Long non-coding RNA CASC2 suppresses pulmonary artery smooth muscle cell proliferation and phenotypic switch in hypoxia-induced pulmonary hypertension
Junsong Gong, Zujun Chen, Yu Chen, Huanran Lv, Haisong Lu, Fuxia Yan, Lihuan Li, Weili Zhang, Jia Shi
Investigating the role of circulating CXCR5-expressing CD8+ T-cells as a biomarker for bacterial infection in subjects with pneumonia
Yu Shen, Qiu-xia Qu, Meng-ni Jin, Cheng Chen
Effect of pirfenidone in patients with more advanced idiopathic pulmonary fibrosis
Ulrich Costabel, Carlo Albera, Marilyn K. Glassberg, Lisa H. Lancaster, Wim A. Wuyts, Ute Petzinger, Frank Gilberg, Klaus-Uwe Kirchgaessler, Paul W. Noble
Body composition, muscle function, and physical performance in fibrotic interstitial lung disease: a prospective cohort study
Sabina A. Guler, Seo Am Hur, Scott A. Lear, Pat G. Camp, Christopher J. Ryerson
The natural history of progressive fibrosing interstitial lung diseases
Martin Kolb, Martina Vašáková
Noninvasive high-frequency oscillatory ventilation as respiratory support in preterm infants: a meta-analysis of randomized controlled trials
Jing Li, Xiaoxia Li, Xianmei Huang, Zhiqun Zhang
The clinical course of idiopathic pulmonary fibrosis and its association to quality of life over time: longitudinal data from the INSIGHTS-IPF registry
Michael Kreuter, Jeff Swigris, David Pittrow, Silke Geier, Jens Klotsche, Antje Prasse, Hubert Wirtz, Dirk Koschel, Stefan Andreas, Martin Claussen, Christian Grohé, Henrike Wilkens, Lars Hagmeyer, Dirk Skowasch, Joachim F. Meyer, Joachim Kirschner, Sven Gläser, Nicolas Kahn, Tobias Welte, Claus Neurohr, Martin Schwaiblmair, Matthias Held, Thomas Bahmer, Tim Oqueka, Marion Frankenberger, Jürgen Behr
Impact of prior and concurrent medication on exacerbation risk with long-acting bronchodilators in chronic obstructive pulmonary disease: a post hoc analysis
Ian Naya, Lee Tombs, David A. Lipson, Isabelle Boucot, Chris Compton
Effects of airway obstruction and hyperinflation on electrocardiographic axes in COPD
Peter Alter, Henrik Watz, Kathrin Kahnert, Klaus F. Rabe, Frank Biertz, Ronald Fischer, Philip Jung, Jana Graf, Robert Bals, Claus F. Vogelmeier, Rudolf A. Jörres
Change in inhaled corticosteroid treatment and COPD exacerbations: an analysis of real-world data from the KOLD/KOCOSS cohorts
Se Hee Lee, Ji-Hyun Lee, Ho Il Yoon, Hye Yun Park, Tae-Hyung Kim, Kwang Ha Yoo, Yeon-Mok Oh, Ki Suk Jung, Sang-Do Lee, Sei Won Lee
Type IV collagen turnover is predictive of mortality in COPD: a comparison to fibrinogen in a prospective analysis of the ECLIPSE cohort
Sarah Rank Rønnow, Jannie Marie Bülow Sand, Lasse Løcke Langholm, Tina Manon-Jensen, Morten Asser Karsdal, Ruth Tal-Singer, Bruce E. Miller, Jørgen Vestbo, Diana Julie Leeming
Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis
Zhaozhong Zhu, Xiaofang Wang, Xihao Li, Yifei Lin, Sipeng Shen, Cong-Lin Liu, Brain D. Hobbs, Kohei Hasegawa, Liming Liang, H. Marike Boezen, Carlos A. Camargo Jr, Michael H. Cho, David C. Christiani
RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD
Jarrett D. Morrow, Robert P. Chase, Margaret M. Parker, Kimberly Glass, Minseok Seo, Miguel Divo, Caroline A. Owen, Peter Castaldi, Dawn L. DeMeo, Edwin K. Silverman, Craig P. Hersh
Effective nebulization of interferon-γ using a novel vibrating mesh
Louise Sweeney, Alice P. McCloskey, Gerard Higgins, Joanne M. Ramsey, Sally-Ann Cryan, Ronan MacLoughlin
Altered irisin/BDNF axis parallels excessive daytime sleepiness in obstructive sleep apnea patients
Csaba E. More, Csaba Papp, Szilvia Harsanyi, Rudolf Gesztelyi, Angela Mikaczo, Gabor Tajti, Laszlo Kardos, Ildiko Seres, Hajnalka Lorincz, Krisztina Csapo, Judit Zsuga
Safety maximization of percutaneous transthoracic needle biopsy with ultrasound guide in subpleural lesions in the evaluation of pulmonary consolidation
Marco Sperandeo, Anna Del Colle, Elisabettamaria Frongillo, Gaetano Rea, Lucia Dimitri, Cristiana Cipriani, Donato Lacedonia
Metformin use mitigates the adverse prognostic effect of diabetes mellitus in chronic obstructive pulmonary disease
Te-Wei Ho, Chun-Ta Huang, Yi-Ju Tsai, Angela Shin-Yu Lien, Feipei Lai, Chong-Jen Yu
AGER expression and alternative splicing in bronchial biopsies of smokers and never smokers
Alen Faiz, Maarten van den Berge, Cornelis J. Vermeulen, Nick H. T. ten Hacken, Victor Guryev, Simon D. Pouwels
Differing severities of acute exacerbations of idiopathic pulmonary fibrosis (IPF): insights from the INPULSIS® trials
Michael Kreuter, Harald Koegler, Matthias Trampisch, Silke Geier, Luca Richeldi
Salicylic acid amplifies Carbachol-induced bronchoconstriction in human precision-cut lung slices
Joseph Jude, Danielle Botelho, Nikhil Karmacharya, Gao Yuan Cao, William Jester, Reynold A. Panettieri Jr
Effect of N-acetylcysteine on exacerbations of bronchiectasis (BENE): a randomized controlled trial
Qian Qi, Yirepanjaing Ailiyaer, Ruijuan Liu, Yan Zhang, Caiyu Li, Mingtao Liu, Xiuxiu Wang, Lijun Jing, Yu Li
Progenitor cell mobilisation and recruitment in pulmonary arteries in chronic obstructive pulmonary disease
Olga Tura-Ceide, Sandra Pizarro, Jéssica García-Lucio, Josep Ramírez, Laureano Molins, Isabel Blanco, Yolanda Torralba, Marta Sitges, Cristina Bonjoch, Victor I. Peinado, Joan Albert Barberà
Estimation of early life endogenous surfactant pool and CPAP failure in preterm neonates with RDS
Roberto Raschetti, Roberta Centorrino, Emmanuelle Letamendia, Alexandra Benachi, Anne Marfaing-Koka, Daniele De Luca
Amelioration of PM2.5-induced lung toxicity in rats by nutritional supplementation with fish oil and Vitamin E
Juan Li, Hang Li, Haibin Li, Weili Guo, Zhen An, Xiang Zeng, Wen Li, Huijun Li, Jie Song, Weidong Wu
Associations of airway tree to lung volume ratio on computed tomography with lung function and symptoms in chronic obstructive pulmonary disease
Naoya Tanabe, Susumu Sato, Tsuyoshi Oguma, Hiroshi Shima, Atsuyasu Sato, Shigeo Muro, Toyohiro Hirai
The value of high-resolution computed tomography (HRCT) to determine exercise ventilatory inefficiency and dynamic hyperinflation in adult patients with cystic fibrosis
Ernesto Crisafulli, Elisabetta Teopompi, Silvia Luceri, Francesco Longo, Panagiota Tzani, Paolo Pagano, Antonella Ielpo, Chiara Longo, Marcello Di Paolo, Nicola Sverzellati, Paolo Palange, Alfredo Chetta, Giovanna Pisi
Silibinin efficacy in a rat model of pulmonary arterial hypertension using monocrotaline and chronic hypoxia
Tingting Zhang, Nanako Kawaguchi, Kenji Yoshihara, Emiko Hayama, Yoshiyuki Furutani, Kayoko Kawaguchi, Takeshi Tanaka, Toshio Nakanishi
Differences in the risk of mood disorders in patients with asthma-COPD overlap and in patients with COPD alone: a nationwide population-based retrospective cohort study in Korea
Hye-Rim Kang, Sung-Hyun Hong, So-Young Ha, Tae-Bum Kim, Eui-Kyung Lee
A prospective multicentre study testing the diagnostic accuracy of an automated cough sound centred analytic system for the identification of common respiratory disorders in children
Paul Porter, Udantha Abeyratne, Vinayak Swarnkar, Jamie Tan, Ti-wan Ng, Joanna M. Brisbane, Deirdre Speldewinde, Jennifer Choveaux, Roneel Sharan, Keegan Kosasih, Phillip Della
Inflammatory responses relate to distinct bronchoalveolar lavage lipidome in community-acquired pneumonia patients: a pilot study
Yali Zheng, Pu Ning, Qiongzhen Luo, Yukun He, Xu Yu, Xiaohui Liu, Yusheng Chen, Xiaorong Wang, Yu Kang, Zhancheng Gao
Oral corticosteroid dose changes and impact on peripheral blood eosinophil counts in patients with severe eosinophilic asthma: a post hoc analysis
Charlene M. Prazma, Elisabeth H. Bel, Robert G. Price, Eric S. Bradford, Frank C. Albers, Steven W. Yancey
The cullin4A is up-regulated in chronic obstructive pulmonary disease patient and contributes to epithelial-mesenchymal transition in small airway epithelium
Yidan Ren, Yi Zhang, Lixia Fan, Qinlian Jiao, Yunshan Wang, Qin Wang
Effect of tiotropium inhaler use on mortality in patients with tuberculous destroyed lung: based on linkage between hospital and nationwide health insurance claims data in South Korea
Ho Cheol Kim, Tae Hoon Kim, Ye-Jee Kim, Chin Kook Rhee, Yeon-Mok Oh
Association of platelet count with all-cause mortality and risk of cardiovascular and respiratory morbidity in stable COPD
Ashraf Fawzy, Julie A. Anderson, Nicholas J. Cowans, Courtney Crim, Robert Wise, Julie C. Yates, Nadia N. Hansel
Human lung fibroblast-to-myofibroblast transformation is not driven by an LDH5-dependent metabolic shift towards aerobic glycolysis
Eva Schruf, Victoria Schroeder, Christian A. Kuttruff, Sabine Weigle, Martin Krell, Maryke Benz, Tom Bretschneider, Alexander Holweg, Michael Schuler, Manfred Frick, Paul Nicklin, James P. Garnett, Mirko C. Sobotta
Antioxidative effects of caffeine in a hyperoxia-based rat model of bronchopulmonary dysplasia
Stefanie Endesfelder, Evelyn Strauß, Till Scheuer, Thomas Schmitz, Christoph Bührer
Importance of the relationship between symptoms and self-reported physical activity level in stable COPD based on the results from the SPACE study
Florin Mihaltan, Yochai Adir, Adam Antczak, Konstantinos Porpodis, Vesna Radulovic, Nuno Pires, Geeuwke Jan de Vries, Andreas Horner, Samuel De Bontridder, Yunqin Chen, Anat Shavit, Silviu Alecu, Lukasz Adamek
Geographies of asthma medication purchase for pre-schoolers in Belgium
Sonia Trabelsi, Lidia Casas, Benoit Nemery, Tim S. Nawrot, Isabelle Thomas
Role of TRPC1 channels in pressure-mediated activation of airway remodeling
Na Li, Ye He, Gang Yang, Qian Yu, Minchao Li
Diagnostic accuracy of capnovolumetry for the identification of airway obstruction – results of a diagnostic study in ambulatory care
Christina Kellerer, Neele Jankrift, Rudolf A. Jörres, Klaus Klütsch, Stefan Wagenpfeil, Klaus Linde, Antonius Schneider
Health status deterioration in subjects with mild to moderate airflow obstruction, a six years observational study
Fernanda Machado Rodrigues, Heleen Demeyer, Matthias Loeckx, Miek Hornikx, Hans Van Remoortel, Wim Janssens, Thierry Troosters
Tobacco exposure inhibits SPLUNC1-dependent antimicrobial activity
Patrick J. Moore, Juliana Sesma, Neil E. Alexis, Robert Tarran
Chitinase-like protein YKL-40 correlates with inflammatory phenotypes, anti-asthma responsiveness and future exacerbations
Lei Liu, Xin Zhang, Ying Liu, Li Zhang, Jing Zheng, Ji Wang, Philip M. Hansbro, Lei Wang, Gang Wang, Alan Chen-Yu Hsu
Aminoguanidine affects systemic and lung inflammation induced by lipopolysaccharide in rats
Saeideh Saadat, Farimah Beheshti, Vahid Reza Askari, Mahmoud Hosseini, Nema Mohamadian Roshan, Mohammad Hossein Boskabady
Potential role of sympathetic activity on the pathogenesis of massive pulmonary embolism with circulatory shock in rabbits
Yuting Wang, Delong Yu, Yijun Yu, Wusong Zou, Xiaohui Zeng, Liqun Hu, Ye Gu
Distinctive lung function trajectories from age 10 to 26 years in men and women and associated early life risk factors – a birth cohort study
Wilfried Karmaus, Nandini Mukherjee, Vimala Devi Janjanam, Su Chen, Hongmei Zhang, Graham Roberts, Ramesh J. Kurukulaaratchy, Hasan Arshad
Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates
Cédric Vonarburg, Marius Loetscher, Martin O. Spycher, Alain Kropf, Marlies Illi, Sharon Salmon, Sean Roberts, Karin Steinfuehrer, Ian Campbell, Sandra Koernig, Joseph Bain, Monika Edler, Ulrich Baumann, Sylvia Miescher, Dennis W. Metzger, Alexander Schaub, Fabian Käsermann, Adrian W. Zuercher
It’s more than low BMI: prevalence of cachexia and associated mortality in COPD
Merry-Lynn N. McDonald, Emiel F. M. Wouters, Erica Rutten, Richard Casaburi, Stephen I. Rennard, David A. Lomas, Marcas Bamman, Bartolome Celli, Alvar Agusti, Ruth Tal-Singer, Craig P. Hersh, Mark Dransfield, Edwin K. Silverman
Spirometric assessment of emphysema presence and severity as measured by quantitative CT and CT-based radiomics in COPD
Mariaelena Occhipinti, Matteo Paoletti, Brian J. Bartholmai, Srinivasan Rajagopalan, Ronald A. Karwoski, Cosimo Nardi, Riccardo Inchingolo, Anna R. Larici, Gianna Camiciottoli, Federico Lavorini, Stefano Colagrande, Vito Brusasco, Massimo Pistolesi
Pulmonary outcomes in adults with a history of Bronchopulmonary Dysplasia differ from patients with asthma
Petra Um-Bergström, Jenny Hallberg, Melvin Pourbazargan, Eva Berggren-Broström, Giovanni Ferrara, Maria J. Eriksson, Sven Nyrén, Jing Gao, Gunnar Lilja, Anders Lindén, Åsa M. Wheelock, Erik Melén, C. Magnus Sköld
Risk factors for diagnostic delay in idiopathic pulmonary fibrosis
Nils Hoyer, Thomas Skovhus Prior, Elisabeth Bendstrup, Torgny Wilcke, Saher Burhan Shaker
Efficacy and safety profile of mucolytic/antioxidant agents in chronic obstructive pulmonary disease: a comparative analysis across erdosteine, carbocysteine, and N-acetylcysteine
Paola Rogliani, Maria Gabriella Matera, Clive Page, Ermanno Puxeddu, Mario Cazzola, Luigino Calzetta
Predictors of death or lung transplant after a diagnosis of idiopathic pulmonary fibrosis: insights from the IPF-PRO Registry
Laurie Snyder, Megan L. Neely, Anne S. Hellkamp, Emily O’Brien, Joao de Andrade, Craig S. Conoscenti, Thomas Leonard, Shaun Bender, Mridu Gulati, Daniel A. Culver, Robert J. Kaner, Scott Palmer, Hyun Joo Kim, Wael Asi, Albert Baker, Scott Beegle, John A. Belperio, Rany Condos, Francis Cordova, Daniel A. Culver, Joao A. M. de Andrade, Daniel Dilling, Kevin Flaherty, Marilyn Glassberg, Mridu Gulati, Kalpalatha Guntupalli, Nishant Gupta, Amy Hajari Case, David Hotchkin, Tristan Huie, Robert Kaner, Hyun Kim, Maryl Kreider, Lisa Lancaster, Joseph Lasky, David Lederer, Doug Lee, Timothy Liesching, Randolph Lipchik, Jason Lobo, Yolanda Mageto, Prema Menon, Lake Morrison, Andrew Namen, Justin Oldham, Rishi Raj, Murali Ramaswamy, Tonya Russell, Paul Sachs, Zeenat Safdar, Barry Sigal, Leann Silhan, Mary Strek, Sally Suliman, Jeremy Tabak, Rajat Walia, Timothy P. Whelan, Julie Fleming, Wendy Morris
Transmembrane-4 L-six family member-1 (TM4SF1) promotes non-small cell lung cancer proliferation, invasion and chemo-resistance through regulating the DDR1/Akt/ERK-mTOR axis
Lin Ye, Chunyun Pu, Jun Tang, Yan Wang, Can Wang, Zhu Qiu, Tingxiu Xiang, Yunmei Zhang, Weiyan Peng
Reliability, validity and responsiveness of E-RS:COPD in patients with spirometric asthma-COPD overlap
Linda M. Nelsen, Laurie A. Lee, Wei Wu, Xiwu Lin, Lindsey Murray, Steven J. Pascoe, Nancy K. Leidy
Efficacy and safety of dupilumab for the treatment of uncontrolled asthma: a meta-analysis of randomized clinical trials
Xiao-feng Xiong, Min Zhu, Hong-xia Wu, Li-li Fan, De-yun Cheng
Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia
Bodil Petersen, Cornelius J. Busch, Grigorij Schleifer, Dominik Schaack, Felix Lasitschka, Kenneth D. Bloch, Donald B. Bloch, Fumito Ichinose
Tyrosine kinase inhibitors relax pulmonary arteries in human and murine precision-cut lung slices
Annette D. Rieg, Nina A. Bünting, Christian Cranen, Said Suleiman, Jan W. Spillner, Heike Schnöring, Thomas Schröder, Saskia von Stillfried, Till Braunschweig, Paul W. Manley, Gereon Schälte, Rolf Rossaint, Stefan Uhlig, Christian Martin
Heterogeneity of cough hypersensitivity mediated by TRPV1 and TRPA1 in patients with chronic refractory cough
Li Long, Hongmei Yao, Jing Tian, Wei Luo, Xinxin Yu, Fang Yi, Qiaoli Chen, Jiaxing Xie, Nanshan Zhong, Kian Fan Chung, Kefang Lai
Airway host-microbiome interactions in chronic obstructive pulmonary disease
Zhang Wang, Barbara Maschera, Simon Lea, Umme Kolsum, David Michalovich, Stephanie Van Horn, Christopher Traini, James R. Brown, Edith M. Hessel, Dave Singh
Chronic obstructive pulmonary disease upper airway microbiota alpha diversity is associated with exacerbation phenotype: a case-control observational study
Alexa A. Pragman, Katherine A. Knutson, Trevor J. Gould, Richard E. Isaacson, Cavan S. Reilly, Chris H. Wendt
The Children’s Respiratory and Environmental Workgroup (CREW) birth cohort consortium: design, methods, and study population
James E. Gern, Daniel J. Jackson, Robert F. Lemanske Jr, Christine M. Seroogy, Umberto Tachinardi, Mark Craven, Stephen Y. Hwang, Carol M. Hamilton, Wayne Huggins, George T. O’Connor, Diane R. Gold, Rachel Miller, Meyer Kattan, Christine C. Johnson, Dennis Ownby, Edward M. Zoratti, Robert A. Wood, Cynthia M. Visness, Fernando Martinez, Anne Wright, Susan Lynch, Carole Ober, Gurjit K. Khurana Hershey, Patrick Ryan, Tina Hartert, Leonard B. Bacharier
Single-photon emission computed tomography/computed tomography imaging of RAGE in smoking-induced lung injury
Monica P. Goldklang, Yared Tekabe, Tina Zelonina, Jordis Trischler, Rui Xiao, Kyle Stearns, Krissy Rodriguez, Alexander Shields, Alexander Romanov, Jeanine M. D’Armiento, Lynne L. Johnson
Lung Cancer development and mortality in interstitial lung disease with and without connective tissue diseases: a five-year Nationwide population-based study
Won-Il Choi, Dong Yoon Lee, Hyun-Gi Choi, Choong Won Lee
Piezo1 induced apoptosis of type II pneumocytes during ARDS
Guo-Peng Liang, Jing Xu, Li-li Cao, Yi-Hua Zeng, Bai-Xu Chen, Jing Yang, Zhong-Wei Zhang, Yan Kang
Pirfenidone attenuates lung fibrotic fibroblast responses to transforming growth factor-β1
Jin Jin, Shinsaku Togo, Kotaro Kadoya, Miniwan Tulafu, Yukiko Namba, Moe Iwai, Junko Watanabe, Kumi Nagahama, Takahiro Okabe, Moulid Hidayat, Yuzo Kodama, Hideya Kitamura, Takashi Ogura, Norikazu Kitamura, Kazuho Ikeo, Shinichi Sasaki, Shigeru Tominaga, Kazuhisa Takahashi
Role of PM2.5 in the development and progression of COPD and its mechanisms
Junling Zhao, Miao Li, Zhihua Wang, Jinkun Chen, Jianping Zhao, Yongjian Xu, Xiang Wei, Jianmao Wang, Jungang Xie
Transection of the cervical sympathetic trunk inhibits the progression of pulmonary arterial hypertension via ERK-1/2 Signalling
Yongpeng Zhao, Rui Xiang, Xin Peng, Qian Dong, Dan Li, Guiquan Yu, Lei Xiao, Shu Qin, Wei Huang
The effect and burden modification of heating on adult asthma hospitalizations in Shijiazhuang: a time-series analysis
Feifei Liu, Fangfang Qu, Huiran Zhang, Lingshan Chao, Rongqin Li, Fengxue Yu, Jitao Guan, Xixin Yan
SU5416 does not attenuate early RV angiogenesis in the murine chronic hypoxia PH model
Grace L. Peloquin, Laura Johnston, Mahendra Damarla, Rachel L. Damico, Paul M. Hassoun, Todd M. Kolb
Is atopy a risk indicator of chronic obstructive pulmonary disease in dairy farmers?
Matthieu Veil-Picard, Thibaud Soumagne, Rechana Vongthilath, Isabella Annesi-Maesano, Alicia Guillien, Lucie Laurent, Pascal Andujar, Nicolas Roche, Stephane Jouneau, Benoit Cypriani, Jean-Jacques Laplante, Bruno Degano, Jean-Charles Dalphin
Genetic influences on the onset of obstructive sleep apnoea and daytime sleepiness: a twin study
Marcell Szily, Adam D. Tarnoki, David L. Tarnoki, Daniel T. Kovacs, Bianka Forgo, Jooyeon Lee, Eunae Kim, Joohon Sung, Laszlo Kunos, Martina Meszaros, Veronika Muller, Andras Bikov
Respiratory virus associated with surgery in children patients
Zhang Dan, Xiuyu Lou, Hao Yan, Junhang Pan, Haiyan Mao, Hongfeng Tang, Yan Shu, Yun Zhao, Lei Liu, Junping Li, Dong Chen, Yanjun Zhang, Xuejun Ma
Demographic and clinical profile of idiopathic pulmonary fibrosis patients in Spain: the SEPAR National Registry
Estrella Fernández-Fabrellas, María Molina-Molina, Joan B. Soriano, José Antonio Rodríguez Portal, Julio Ancochea, Claudia Valenzuela, Antoni Xaubet, M. Aburto Barrenetxea, I. Alfageme Michavila, E. Bollo de Miguel, E. Cano, A. Casanova Espinosa, D. Castillo Villegas, J. A. Figuerola Mendal, R. García Sevila, J. I. Gaudó Navarro, L. Gómez Carrera, J. M. González, S. Herrera Lara, R. Laporta Hernández, M. Marín González, M. A. Nieto Barbero, K. Portillo, A. D. Romero, R. Sánchez Simón-Talero, J. N. Sancho Chust, J. Sellarés Torres, M. J. Soler Sempere, J. Sauleda Roig, L. Tomás López, M. Villanueva Montes
Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers
Michael E. O’Brien, Divay Chandra, Robert C. Wilson, Chad M. Karoleski, Carl R. Fuhrman, Joseph K. Leader, Jiantao Pu, Yingze Zhang, Alison Morris, Seyed Nouraie, Jessica Bon, Zsolt Urban, Frank C. Sciurba
Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia
Ari Jon Arason, Jon Petur Joelsson, Bryndis Valdimarsdottir, Snaevar Sigurdsson, Alexander Gudjonsson, Skarphedinn Halldorsson, Freyr Johannsson, Ottar Rolfsson, Fredrik Lehmann, Saevar Ingthorsson, Paulina Cherek, Gudmundur H. Gudmundsson, Fridrik R. Gardarsson, Clive P. Page, Olafur Baldursson, Thorarinn Gudjonsson, Jennifer A. Kricker
Dysregulated expression of hypoxia-inducible factors augments myofibroblasts differentiation in idiopathic pulmonary fibrosis
Arnoldo Aquino-Gálvez, Georgina González-Ávila, Laura Lorena Jiménez-Sánchez, Héctor Aquiles Maldonado-Martínez, José Cisneros, Fernanda Toscano-Marquez, Manuel Castillejos-López, Luz María Torres-Espíndola, Rafael Velázquez-Cruz, Víctor Hugo Olivera Rodríguez, Edgar Flores-Soto, Héctor Solís-Chagoyán, Carlos Cabello, Joaquín Zúñiga, Yair Romero
Reverse-D-4F improves endothelial progenitor cell function and attenuates LPS-induced acute lung injury
Nana Yang, Hua Tian, Enxin Zhan, Lei Zhai, Peng Jiao, Shutong Yao, Guohua Lu, Qingjie Mu, Juan Wang, Aihua Zhao, Yadong Zhou, Shucun Qin
Evaluation of systemic absorption and bronchodilator effect of glycopyrronium bromide delivered by nebulizer or a dry powder inhaler in subjects with chronic obstructive pulmonary disease
Brian R. Leaker, Dave Singh, Grant C. Nicholson, Blanka Hezelova, Thomas Goodin, Ayca Ozol-Godfrey, Gerald Galluppi, Peter J. Barnes
CFTR regulates B cell activation and lymphoid follicle development
Francesca Polverino, Bao Lu, Joselyn Rojas Quintero, Sara O. Vargas, Avignat S. Patel, Caroline A. Owen, Norma P. Gerard, Craig Gerard, Manuela Cernadas
From bench to bedside: in vitro and in vivo evaluation of a neonate-focused nebulized surfactant delivery strategy
F. Bianco, F. Ricci, C. Catozzi, X. Murgia, M. Schlun, A. Bucholski, U. Hetzer, S. Bonelli, M. Lombardini, E. Pasini, M. Nutini, M. Pertile, S. Minocchieri, M. Simonato, B. Rosa, G. Pieraccini, G. Moneti, L. Lorenzini, S. Catinella, G. Villetti, M. Civelli, B. Pioselli, P. Cogo, V. Carnielli, C. Dani, F. Salomone
Effect of smoking status on lung function, patient-reported outcomes, and safety among COPD patients treated with glycopyrrolate inhalation powder: pooled analysis of GEM1 and GEM2 studies
Donald P. Tashkin, Thomas Goodin, Alyssa Bowling, Barry Price, Ayca Ozol-Godfrey, Sanjay Sharma, Shahin Sanjar
Prevalence of and risk factors for pulmonary complications after curative resection in otherwise healthy elderly patients with early stage lung cancer
Yunjoo Im, Hye Yun Park, Sumin Shin, Sun Hye Shin, Hyun Lee, Joong Hyun Ahn, Insuk Sohn, Jong Ho Cho, Hong Kwan Kim, Jae Ill Zo, Young Mog Shim, Ho Yun Lee, Jhingook Kim
Pulmonary gas exchange in hereditary hemorrhagic telangiectasia patients with liver arteriovenous malformations
Carole de Picciotto, Mostafa El Hajjam, Carma Karam, Thierry Chinet, Marcel Bonay
Pleural thickening on screening chest X-rays: a single institutional study
Akira Saito, Yukichika Hakamata, Yukiko Yamada, Mitsuhiro Sunohara, Megumi Tarui, Yoko Murano, Akihisa Mitani, Kimie Tanaka, Takahide Nagase, Shintaro Yanagimoto
Ambient air pollution and respiratory mortality in Xi’an, China: a time-series analysis
Kingsley Katleho Mokoena, Crystal Jane Ethan, Yan Yu, Karabo Shale, Feng Liu
Bleeding risk of transbronchial cryobiopsy compared to transbronchial forceps biopsy in interstitial lung disease – a prospective, randomized, multicentre cross-over trial
Juergen Hetzel, Ralf Eberhardt, Christoph Petermann, Wolfgang Gesierich, Kaid Darwiche, Lars Hagmeyer, Rainer Muche, Michael Kreuter, Richard Lewis, Ahmed Ehab, Michael Boeckeler, Maik Haentschel
Weighing the evidence for pharmacological treatment interventions in mild COPD; a narrative perspective
Dave Singh, Anthony D. D’Urzo, James F. Donohue, Edward M. Kerwin
Feasibility of low dose chest CT for virtual bronchoscopy navigation in a porcine model
Insu Kim, Geewon Lee, Jung Seop Eom, Hyo Yeong Ahn, Ahreum Kim
COL6A3 polymorphisms were associated with lung cancer risk in a Chinese population
Ying Duan, Gaowen Liu, Yao Sun, Jiamin Wu, Zichao Xiong, Tianbo Jin, Mingwei Chen
Chronic obstructive pulmonary disease in rheumatoid arthritis: a systematic review and meta-analysis
Yubo Ma, Hui Tong, Xu Zhang, Mengmeng Wang, Jiajia Yang, Meng Wu, Renfang Han, Mengya Chen, Xingxing Hu, Yaping Yuan, Guixia Pan, Yanfeng Zou, Shengqian Xu, Faming Pan
Do blood eosinophils strictly reflect airway inflammation in COPD? Comparison with asthmatic patients
Patrizia Pignatti, Dina Visca, Francesca Cherubino, Elisabetta Zampogna, Etienne Lucini, Laura Saderi, Giovanni Sotgiu, Antonio Spanevello
Effects of use of an eHealth platform e-Vita for COPD patients on disease specific quality of life domains
Esther P.W.A. Talboom-Kamp, Marije S. Holstege, Niels H. Chavannes, Marise J. Kasteleyn
Correction to: Scored minor criteria for severe community-acquired pneumonia predicted better
Qi Guo, Wei-dong Song, Hai-yan Li, Yi-ping Zhou, Ming Li, Xiao-ke Chen, Hui Liu, Hong-lin Peng, Hai-qiong Yu, Xia Chen, Nian Liu, Zhong-dong Lü, Li-hua Liang, Qing-zhou Zhao, Mei Jiang
Biomarkers of collagen synthesis predict progression in the PROFILE idiopathic pulmonary fibrosis cohort
Louise A. Organ, Anne-Marie R. Duggan, Eunice Oballa, Sarah C. Taggart, Juliet K. Simpson, Arthur R. Kang’ombe, Rebecca Braybrooke, Philip L. Molyneaux, Bernard North, Yakshitha Karkera, Diana J. Leeming, Morten A. Karsdal, Carmel B. Nanthakumar, William A. Fahy, Richard P. Marshall, R. Gisli Jenkins, Toby M. Maher
Dose variability of supplemental oxygen therapy with open patient interfaces based on in vitro measurements using a physiologically realistic upper airway model
Ira Katz, John Chen, Kelvin Duong, Kaixian Zhu, Marine Pichelin, Georges Caillibotte, Andrew R. Martin
Rhinovirus replication and innate immunity in highly differentiated human airway epithelial cells
Stephanie M. Warner, Shahina Wiehler, Aubrey N. Michi, David Proud
Consequences of chronic kidney disease in chronic obstructive pulmonary disease
Franziska C. Trudzinski, Mohamad Alqudrah, Albert Omlor, Stephen Zewinger, Danilo Fliser, Timotheus Speer, Frederik Seiler, Frank Biertz, Armin Koch, Claus Vogelmeier, Tobias Welte, Henrik Watz, Benjamin Waschki, Sebastian Fähndrich, Rudolf Jörres, Robert Bals
Multi-level immune response network in mild-moderate Chronic Obstructive Pulmonary Disease (COPD)
Tamara Cruz, Alejandra López-Giraldo, Guillaume Noell, Sandra Casas-Recasens, Tamara Garcia, Laureano Molins, Manel Juan, Marco A. Fernandez, Alvar Agustí, Rosa Faner
Imaging-based clusters in former smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and intermediate outcome measures in COPD study (SPIROMICS)
Babak Haghighi, Sanghun Choi, Jiwoong Choi, Eric A. Hoffman, Alejandro P. Comellas, John D. Newell Jr, Chang Hyun Lee, R. Graham Barr, Eugene Bleecker, Christopher B. Cooper, David Couper, Mei Lan Han, Nadia N. Hansel, Richard E. Kanner, Ella A. Kazerooni, Eric A. C. Kleerup, Fernando J. Martinez, Wanda O’Neal, Robert Paine III, Stephen I. Rennard, Benjamin M. Smith, Prescott G. Woodruff, Ching-Long Lin
Postoperative acute exacerbation of interstitial pneumonia in pulmonary and non-pulmonary surgery: a retrospective study
Takuto Miyamura, Noriho Sakamoto, Tomoyuki Kakugawa, Daisuke Okuno, Hirokazu Yura, Shota Nakashima, Hiroshi Ishimoto, Takashi Kido, Daisuke Taniguchi, Takuro Miyazaki, Tomoshi Tsuchiya, Shin Tsutsui, Hiroyuki Yamaguchi, Yasushi Obase, Yuji Ishimatsu, Kazuto Ashizawa, Takeshi Nagayasu, Hiroshi Mukae
Effects of crystalloid, hyper-oncotic albumin, and iso-oncotic albumin on lung and kidney damage in experimental acute lung injury
Renata de S. Mendes, Milena V. Oliveira, Gisele A. Padilha, Nazareth N. Rocha, Cintia L. Santos, Ligia A. Maia, Marcos V. de S. Fernandes, Fernanda F. Cruz, Priscilla C. Olsen, Vera L. Capelozzi, Marcelo Gama de Abreu, Paolo Pelosi, Patricia R. M. Rocco, Pedro L. Silva
Dysregulation of the endothelial nitric oxide pathway is associated with airway inflammation in COPD
Balázs Csoma, András Bikov, Lajos Nagy, Bence Tóth, Tamás Tábi, Gergő Szűcs, Zsolt István Komlósi, Veronika Müller, György Losonczy, Zsófia Lázár
Bronchial thermoplasty increases airway volume measured by functional respiratory imaging
D. Langton, G. Sloan, C. Banks, K. Bennetts, V. Plummer, F. Thien
Tracing exogenous surfactant in vivo in rabbits by the natural variation of 13C
Sonia Giambelluca, Francesca Ricci, Manuela Simonato, Luca Vedovelli, Umberto Traldi, Alessio Correani, Costanza Casiraghi, Matteo Storti, Arianna Mersanne, Paola Cogo, Fabrizio Salomone, Virgilio P. Carnielli
Peak expiratory flow as an endpoint for clinical trials in asthma: a comparison with FEV1
David M. G. Halpin, Eli O. Meltzer, Wendelgard Pisternick-Ruf, Petra Moroni-Zentgraf, Michael Engel, Liliana Zaremba-Pechmann, Thomas Casale, J. Mark FitzGerald
DSP variants may be associated with longitudinal change in quantitative emphysema
Woori Kim, Michael H. Cho, Phuwanat Sakornsakolpat, David A. Lynch, Harvey O. Coxson, Ruth Tal-Singer, Edwin K. Silverman, Terri H. Beaty
Meta-analysis of vitamin D and lung function in patients with asthma
Jian Liu, Yong-Quan Dong, Jie Yin, Jian Yao, Jie Shen, Guo-Jie Sheng, Kun Li, Hai-Feng Lv, Xing Fang, Wei-Fang Wu
Use of precision cut lung slices as a translational model for the study of lung biology
Guanghui Liu, Catherine Betts, Danen M. Cunoosamy, Per M. Åberg, Jorrit J. Hornberg, Kinga Balogh Sivars, Taylor S. Cohen
Tenofovir alafenamide fumarate attenuates bleomycin-induced pulmonary fibrosis by upregulating the NS5ATP9 and TGF-β1/Smad3 signaling pathway
Lingxia Li, Jing Zhao, Li Zhou, Jie Chen, Yuanyuan Ma, Yanyan Yu, Jun Cheng
The canonical TGF-β/Smad signalling pathway is involved in PD-L1-induced primary resistance to EGFR-TKIs in EGFR-mutant non-small-cell lung cancer
Yang Zhang, Yuanyuan Zeng, Ting Liu, Wenwen Du, Jianjie Zhu, Zeyi Liu, Jian-an Huang
Complement factor C5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model
Jack Yang, Ivan Ramirez Moral, Cornelis van ’t Veer, Alex F. de Vos, Regina de Beer, Joris J. T. H. Roelofs, B. Paul Morgan, Tom van der Poll
Pulmonary rehabilitation, physical activity and aortic stiffness in COPD
Yousef S. Aldabayan, Heidi A. Ridsdale, Ahmed M. Alrajeh, Abdulelah M. Aldhahir, Arthur Lemson, Jaber S. Alqahtani, Jeremy S. Brown, John R. Hurst
Bone and ocular safety of budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a 52-week randomized study
Edward M. Kerwin, Gary T. Ferguson, Mindy Mo, Kiernan DeAngelis, Paul Dorinsky
Anti-fibrotic effects of tannic acid through regulation of a sustained TGF-beta receptor signaling
Eleanor B. Reed, Shawn Ard, Jennifer La, Chan Young Park, Laura Culligan, Jeffrey J. Fredberg, Larisa V. Smolyaninova, Sergei N. Orlov, Bohao Chen, Robert Guzy, Gökhan M. Mutlu, Nickolai O. Dulin
Mepolizumab reduces exacerbations in patients with severe eosinophilic asthma, irrespective of body weight/body mass index: meta-analysis of MENSA and MUSCA
Frank C. Albers, Alberto Papi, Camille Taillé, Daniel J. Bratton, Eric S. Bradford, Steven W. Yancey, Namhee Kwon
Neutrophil elastase as a biomarker for bacterial infection in COPD
Samantha J. Thulborn, Vijay Mistry, Christopher E. Brightling, Kelly L. Moffitt, David Ribeiro, Mona Bafadhel
Systemic Immuno-metabolic alterations in chronic obstructive pulmonary disease (COPD)
Amit R Agarwal, Smita Kadam, Ankita Brahme, Manas Agrawal, Komalkirti Apte, Govinda Narke, Kushal Kekan, Sapna Madas, Sundeep Salvi
Defining a role for lung function associated gene GSTCD in cell homeostasis
Amanda P. Henry, Kelly Probert, Ceri E. Stewart, Dhruma Thakker, Sangita Bhaker, Sheyda Azimi, Ian P. Hall, Ian Sayers
Can medicines development improve outcomes in asthma and chronic obstructive pulmonary disease management by driving effectiveness?
David A. Leather, Louisa Yates, Henrik Svedsater, Loretta Jacques, Susan Collier, Danielle Powell, Rupert Jones
Identification of genetic factors underlying persistent pulmonary hypertension of newborns in a cohort of Chinese neonates
Xu Liu, Mei Mei, Xiang Chen, Yulan Lu, Xinran Dong, Liyuan Hu, Xiaojing Hu, Guoqiang Cheng, Yun Cao, Lin Yang, Wenhao Zhou
Mass spectrometry imaging as a tool for evaluating the pulmonary distribution of exogenous surfactant in premature lambs
Riccardo Zecchi, Pietro Franceschi, Laura Tigli, Francesca Ricci, Francesca Boscaro, Barbara Pioselli, Valentina Mileo, Xabier Murgia, Federico Bianco, Fabrizio Salomone, Augusto F. Schmidt, Noah H. Hillman, Matthew W. Kemp, Alan H. Jobe
Effect of short-term oral prednisone therapy on blood gene expression: a randomised controlled clinical trial
Hiroto Takiguchi, Virginia Chen, Ma’en Obeidat, Zsuzsanna Hollander, J. Mark FitzGerald, Bruce M. McManus, Raymond T. Ng, Don D. Sin
Clinical outcomes of radial probe endobronchial ultrasound using a guide sheath for diagnosis of peripheral lung lesions in patients with pulmonary emphysema
Kyu Min Lee, Geewon Lee, Ahreum Kim, Jeongha Mok, Ji Won Lee, Yeon Joo Jeong, Eun-Jung Jo, Mi Hyun Kim, Kwangha Lee, Ki Uk Kim, Hye-Kyung Park, Min Ki Lee, Jung Seop Eom
Evaluation of exacerbations and blood eosinophils in UK and US COPD populations
Claus F. Vogelmeier, Konstantinos Kostikas, Juanzhi Fang, Hengfeng Tian, Bethan Jones, Christopher Ll Morgan, Robert Fogel, Florian S. Gutzwiller, Hui Cao
Monoclonal antibodies in type 2 asthma: a systematic review and network meta-analysis
Ahmed Edris, Silke De Feyter, Tania Maes, Guy Joos, Lies Lahousse
Effect of the inhaled PDE4 inhibitor CHF6001 on biomarkers of inflammation in COPD
Dave Singh, Kai Michael Beeh, Brendan Colgan, Oliver Kornmann, Brian Leaker, Henrik Watz, Germano Lucci, Silvia Geraci, Aida Emirova, Mirco Govoni, Marie Anna Nandeuil
Role of KRAS in regulating normal human airway basal cell differentiation
Fumihiro Ogawa, Matthew S. Walters, Afrah Shafquat, Sarah L. O’Beirne, Robert J. Kaner, Jason G. Mezey, Haijun Zhang, Philip L. Leopold, Ronald G. Crystal
Myelodysplastic syndromes and idiopathic pulmonary fibrosis: a dangerous liaison
Spyros A. Papiris, Panagiotis Tsirigotis, Caroline Kannengiesser, Lykourgos Kolilekas, Konstantinos Gkirkas, Andriana I. Papaioannou, Patrick Revy, Paschalina Giouleka, Georgia Papadaki, Konstantinos Kagouridis, Vassiliki Pappa, Raphael Borie, Catherine Boileau, Demosthenes Bouros, Bruno Crestani, Effrosyni D. Manali
It is time to change the way we manage mild asthma: an update in GINA 2019
Jaya Muneswarao, Mohamed Azmi Hassali, Baharudin Ibrahim, Bandana Saini, Irfhan Ali Hyder Ali, Ashutosh Kumar Verma
IL-22Ra1 is induced during influenza infection by direct and indirect TLR3 induction of STAT1
K. D. Hebert, N. Mclaughlin, Zhe Zhang, A. Cipriani, J. F. Alcorn, D. A. Pociask
Comparison of tumor cell numbers and 22C3 PD-L1 expression between cryobiopsy and transbronchial biopsy with endobronchial ultrasonography-guide sheath for lung cancer
Ken Arimura, Mitsuko Kondo, Yoji Nagashima, Masato Kanzaki, Fumi Kobayashi, Kiyoshi Takeyama, Jun Tamaoki, Etsuko Tagaya
Decline of COPD exacerbations in clinical trials over two decades – a systematic review and meta-regression
Stefan Andreas, Christian Röver, Judith Heinz, Sebastian Straube, Henrik Watz, Tim Friede
A decision tree built with parameters obtained by computed tomographic pulmonary angiography is useful for predicting adverse outcomes in non-high-risk acute pulmonary embolism patients
Dong Jia, Xue-lian Li, Qin Zhang, Gang Hou, Xiao-ming Zhou, Jian Kang
Circulating ESM-1 levels are correlated with the presence of coronary artery disease in patients with obstructive sleep apnea
Haili Sun, Fang Fang, Kun Li, Huina Zhang, Ming Zhang, Lichuan Zhang, Juan Li, Yanwen Qin, Yongxiang Wei
Are there specific clinical characteristics associated with physician’s treatment choices in COPD?
Nicolas Roche, Anestis Antoniadis, David Hess, Pei Zhi Li, Eric Kelkel, Sylvie Leroy, Christophe Pison, Pierre-Régis Burgel, Bernard Aguilaniu
Compartmentalization of anti-oxidant and anti-inflammatory gene expression in current and former smokers with COPD
Venkataramana K. Sidhaye, Janet T. Holbrook, Alyce Burke, Kuladeep R. Sudini, Sanjay Sethi, Gerard J. Criner, Jed W. Fahey, Charles S. Berenson, Michael R. Jacobs, Rajesh Thimmulappa, Robert A. Wise, Shyam Biswal
Relationship between gender and survival in a real-life cohort of patients with COPD
Maeva Zysman, Pierre-Régis Burgel, Isabelle Court-Fortune, Graziella Brinchault-Rabin, Pascale Nesme-Meyer, Pascale Surpas, Gaetan Deslée, Thierry Perez, Olivier Le Rouzic, Gilles Jebrak, Pascal Chanez, Jean-Louis Paillasseur, Denis Caillaud, Nicolas Roche, P. R. Burgel, G. Deslee, P. Surpas, O. Le Rouzic, T. Perez, N. Roche, G. Brinchault-Rabin, D. Caillaud, P. Chanez, I. Court-Fortune, R. Escamilla, G. Jebrak, P. Nesme-Meyer, M. Zysman, C. Pinet, Brigitte Risse
Lipoxin A4 ameliorates lipopolysaccharide-induced lung injury through stimulating epithelial proliferation, reducing epithelial cell apoptosis and inhibits epithelial–mesenchymal transition
Jing-xiang Yang, Ming Li, Xin-ou Chen, Qing-quan Lian, Qian Wang, Fang Gao, Sheng-wei Jin, Sheng-xing Zheng
Critical combination of initial markers for predicting refractory Mycoplasma pneumoniae pneumonia in children: a case control study
Young-Jin Choi, Ju-Hee Jeon, Jae-Won Oh
Inhibition of lung cancer cells and Ras/Raf/MEK/ERK signal transduction by ectonucleoside triphosphate phosphohydrolase-7 (ENTPD7)
Zhongwei Wen, Rongfang Jiang, Ying Huang, Zhineng Wen, Dong Rui, Xiaoxiao Liao, Zhougui Ling
Circulating neutrophils levels are a predictor of pneumonia risk in chronic obstructive pulmonary disease
Steven J. Pascoe, Alberto Papi, Dawn Midwinter, Sally Lettis, Neil Barnes
Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity
Guoqing Wang, Howard H. Lou, Jacqueline Salit, Philip L. Leopold, Sharon Driscoll, Juergen Schymeinsky, Karsten Quast, Sudha Visvanathan, Jay S. Fine, Matthew J. Thomas, Ronald G. Crystal
The interleukin-33 receptor contributes to pulmonary responses to ozone in male mice: role of the microbiome
David I. Kasahara, Jeremy E. Wilkinson, Youngji Cho, Aline P. Cardoso, Curtis Huttenhower, Stephanie A. Shore
Predictive value of a series of inflammatory markers in COPD for lung cancer diagnosis: a case-control study
Cecilia Mouronte-Roibás, Virginia Leiro-Fernández, Alberto Ruano-Raviña, Cristina Ramos-Hernández, Pedro Casado-Rey, Maribel Botana-Rial, Esmeralda García-Rodríguez, Alberto Fernández-Villar
Validation of the IPF-specific version of St. George’s Respiratory Questionnaire
Thomas Skovhus Prior, Nils Hoyer, Saher Burhan Shaker, Jesper Rømhild Davidsen, Janelle Yorke, Ole Hilberg, Elisabeth Bendstrup
Reduced expression of the Ion channel CFTR contributes to airspace enlargement as a consequence of aging and in response to cigarette smoke in mice
Jack H. Wellmerling, Sheng-Wei Chang, Eunsoo Kim, Wissam H. Osman, Prosper N. Boyaka, Michael T. Borchers, Estelle Cormet-Boyaka
Lyn regulates epithelial–mesenchymal transition in CS-exposed model through Smad2/3 signaling
Xiaobo Liang, Xiang He, Yin Li, Junyi Wang, Dehong Wu, Xiefang Yuan, Xiaoyun Wang, Guoping Li
Roles of MYC-targeting long non-coding RNA MINCR in cell cycle regulation and apoptosis in non-small cell lung Cancer
Shengjie Chen, Tianyi Gu, Ziwen Lu, Lipeng Qiu, Guoliang Xiao, Xiaozhong Zhu, Feng Li, Hui Yu, Gang Li, Hanqing Liu
High level of fluorescent oxidation products and worsening of asthma control over time
Zeina Akiki, Miora Andrianjafimasy, Farid Zerimech, Nicole Le Moual, Valérie Siroux, Orianne Dumas, Régis Matran, Rachel Nadif
Wnt signaling regulates trans-differentiation of stem cell like type 2 alveolar epithelial cells to type 1 epithelial cells
Elhusseiny Mohamed Mahmud Abdelwahab, Judit Rapp, Diana Feller, Veronika Csongei, Szilard Pal, Domokos Bartis, David R. Thickett, Judit Erzsebet Pongracz
Antifibrotic therapy for idiopathic pulmonary fibrosis: time to treat
Toby M. Maher, Mary E. Strek
Interferon-γ enhances the antifibrotic effects of pirfenidone by attenuating IPF lung fibroblast activation and differentiation
Tuong N. Vu, Xuesong Chen, Hussein D. Foda, Gerald C. Smaldone, Nadia A. Hasaneen
Factors leading to failure to diagnose pulmonary malignant tumors using endobronchial ultrasound with guide sheath within the target lesion
Yoichi Nishii, Taro Yasuma, Kentaro Ito, Yuta Suzuki, Fumiaki Watanabe, Tetsu Kobayashi, Kota Nishihama, Corina N. D’Alessandro-Gabazza, Hajime Fujimoto, Esteban C. Gabazza, Fumihiro Asano, Osamu Taguchi, Osamu Hataji
Clinical outcomes stratified by baseline functional class after initial combination therapy for pulmonary arterial hypertension
R. James White, Anton Vonk-Noordegraaf, Stephan Rosenkranz, Ronald J. Oudiz, Vallerie V. McLaughlin, Marius M. Hoeper, Ekkehard Grünig, Hossein-Ardeschir Ghofrani, Murali M. Chakinala, Joan A. Barberà, Christiana Blair, Jonathan Langley, Adaani E. Frost
Is the 2013 American Thoracic Society CPAP-tracking system algorithm useful for managing non-adherence in long-term CPAP-treated patients?
Marie-Caroline Rotty, Jean-Pierre Mallet, Carey M. Suehs, Christian Martinez, Jean-Christian Borel, Claudio Rabec, Arnaud Bourdin, Nicolas Molinari, Dany Jaffuel
Molecular detection of respiratory pathogens and typing of human rhinovirus of adults hospitalized for exacerbation of asthma and chronic obstructive pulmonary disease
Fanny Wai-san Ko, Paul Kay-sheung Chan, Renee W. Y. Chan, Ka-Pang Chan, April Ip, Angela Kwok, Jenny Chun-li Ngai, So-Shan Ng, Chan Tat On, David Shu-cheong Hui
Determination of reliable lung function parameters in intubated mice
Eline Bonnardel, Renaud Prevel, Marilyne Campagnac, Marielle Dubreuil, Roger Marthan, Patrick Berger, Isabelle Dupin
Prevalence and course of disease after lung resection in primary ciliary dyskinesia: a cohort & nested case-control study
Panayiotis Kouis, Myrofora Goutaki, Florian S. Halbeisen, Ifigeneia Gioti, Nicos Middleton, Israel Amirav, Angelo Barbato, Laura Behan, Mieke Boon, Nagehan Emiralioglu, Eric G. Haarman, Bulent Karadag, Cordula Koerner-Rettberg, Romain Lazor, Michael R. Loebinger, Bernard Maitre, Henryk Mazurek, Lucy Morgan, Kim Gjerum Nielsen, Heymut Omran, Ugur Özçelik, Mareike Price, Andrzej Pogorzelski, Deborah Snijders, Guillaume Thouvenin, Claudius Werner, Zorica Zivkovic, Claudia E. Kuehni, Panayiotis K. Yiallouros
Association of time-to-treatment with outcomes of Pneumocystis pneumonia with respiratory failure in HIV-negative patients
Ryoung-Eun Ko, Soo Jin Na, Kyungmin Huh, Gee Young Suh, Kyeongman Jeon
Surfactant Protein A in particles in exhaled air (PExA), bronchial lavage and bronchial wash - a methodological comparison
Annelie F. Behndig, Ekaterina Mirgorodskaya, Anders Blomberg, Anna-Carin Olin
Direct and indirect costs of COPD progression and its comorbidities in a structured disease management program: results from the LQ-DMP study
Florian Kirsch, Anja Schramm, Larissa Schwarzkopf, Johanna I. Lutter, Boglárka Szentes, Manuel Huber, Reiner Leidl
Volumetric characteristics of idiopathic pulmonary fibrosis lungs: computational analyses of high-resolution computed tomography images of lung lobes
Bora Sul, Lucia Flors, Joanne Cassani, Michael J. Morris, Jaques Reifman, Talissa Altes, Anders Wallqvist
Icotinib-resistant HCC827 cells produce exosomes with mRNA MET oncogenes and mediate the migration and invasion of NSCLC
Yiming Yu, Maidinaimu Abudula, Chaofen Li, Zhongbo Chen, Yun Zhang, Yichen Chen
Semi-quantitative visual assessment of chest radiography is associated with clinical outcomes in critically ill patients
Stefanie E. Mason, Paul B. Dieffenbach, Joshua A. Englert, Angela A. Rogers, Anthony F. Massaro, Laura E. Fredenburgh, Angelica Higuera, Mayra Pinilla-Vera, Marta Vilas, Raul San Jose Estepar, George R. Washko, Rebecca M. Baron, Samuel Y. Ash
Plasma metabolomics and clinical predictors of survival differences in COPD patients
Victor Pinto-Plata, Ciro Casanova, Miguel Divo, Yohannes Tesfaigzi, Vince Calhoun, Jing Sui, Francesca Polverino, Carmen Priolo, Hans Petersen, Juan Pablo de Torres, Jose Maria Marin, Caroline A. Owen, Rebeca Baz, Elizabeth Cordova, Bartolome Celli
Identifying tuberculous pleural effusion using artificial intelligence machine learning algorithms
Zenghua Ren, Yudan Hu, Ling Xu
Influence of β2 adrenergic receptor genotype on risk of nocturnal ventilation in patients with Duchenne muscular dystrophy
Eli F. Kelley, Troy J. Cross, Eric M. Snyder, Craig M. McDonald, Eric P. Hoffman, Luca Bello
Protein phosphatase 2A (PP2A): a key phosphatase in the progression of chronic obstructive pulmonary disease (COPD) to lung cancer
Cassandra P. Nader, Aylin Cidem, Nicole M. Verrills, Alaina J. Ammit
Primary drug resistance of mycobacterium tuberculosis in Shandong, China, 2004–2018
Wan-mei Song, Yi-fan Li, Xiao-bin Ma, Jin-yue Liu, Ning-ning Tao, Yao Liu, Qian-yun Zhang, Ting-ting Xu, Shi-jin Li, Chun-Bao Yu, Lei Gao, Liang-liang Cui, Huai-chen Li
Insufficient serum L-ficolin is associated with disease presence and extent of pulmonary Mycobacterium avium complex disease
Tomofumi Kobayashi, Koji Kuronuma, Atsushi Saito, Kimiyuki Ikeda, Shigeru Ariki, Atsushi Saitou, Mitsuo Otsuka, Hirofumi Chiba, Satoshi Takahashi, Motoko Takahashi, Hiroki Takahashi
miR-335-5p inhibits TGF-β1-induced epithelial–mesenchymal transition in non-small cell lung cancer via ROCK1
Wenwen Du, Haicheng Tang, Zhe Lei, Jianjie Zhu, Yuanyuan Zeng, Zeyi Liu, Jian-an Huang
Computed tomography-derived area and density of pectoralis muscle associated disease severity and longitudinal changes in chronic obstructive pulmonary disease: a case control study
So Hyeon Bak, Sung Ok Kwon, Seon-Sook Han, Woo Jin Kim
Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO Registry
Jamie L. Todd, Megan L. Neely, Robert Overton, Katey Durham, Mridu Gulati, Howard Huang, Jesse Roman, L. Kristin Newby, Kevin R. Flaherty, Richard Vinisko, Yi Liu, Janine Roy, Ramona Schmid, Benjamin Strobel, Christian Hesslinger, Thomas B. Leonard, Imre Noth, John A. Belperio, Scott M. Palmer, Wael Asi, Albert Baker, Scott Beegle, John A. Belperio, Rany Condos, Francis Cordova, Daniel A. Culver, Joao A. M. de Andrade, Daniel Dilling, Kevin R. Flaherty, Marilyn Glassberg, Mridu Gulati, Kalpalatha Guntupalli, Nishant Gupta, Amy Hajari Case, David Hotchkin, Tristan Huie, Robert Kaner, Hyun Kim, Maryl Kreider, Lisa Lancaster, Joseph Lasky, David Lederer, Doug Lee, Timothy Liesching, Randolph Lipchik, Jason Lobo, Yolanda Mageto, Prema Menon, Lake Morrison, Andrew Namen, Justin Oldham, Rishi Raj, Murali Ramaswamy, Tonya Russell, Paul Sachs, Zeenat Safdar, Barry Sigal, Leann Silhan, Mary Strek, Sally Suliman, Jeremy Tabak, Rajat Walia, Timothy P. Whelan
Rupintrivir reduces RV-induced TH-2 cytokine IL-4 in precision-cut lung slices (PCLS) of HDM-sensitized mice ex vivo
Olga Danov, Lisa Lasswitz, Helena Obernolte, Christina Hesse, Armin Braun, Sabine Wronski, Katherina Sewald
Global prevalence of asthma-COPD overlap (ACO) in the general population: a systematic review and meta-analysis
Mostafa Hosseini, Amir Almasi-Hashiani, Mahdi Sepidarkish, Saman Maroufizadeh
Inhibition of Aurora A enhances radiosensitivity in selected lung cancer cell lines
Ningbo Liu, Yong Antican Wang, Yunguang Sun, Jeffrey Ecsedy, Jifeng Sun, Xue Li, Ping Wang
Longitudinal clinical outcomes in a real-world population of patients with idiopathic pulmonary fibrosis: the PROOF registry
Wim A. Wuyts, Caroline Dahlqvist, Hans Slabbynck, Marc Schlesser, Natacha Gusbin, Christophe Compere, Sofie Maddens, Yuan-Chi Lee, Klaus-Uwe Kirchgaessler, Karen Bartley, Benjamin Bondue
Enhanced Bruton’s tyrosine kinase in B-cells and autoreactive IgA in patients with idiopathic pulmonary fibrosis
Peter Heukels, Jennifer A. C. van Hulst, Menno van Nimwegen, Carian E. Boorsma, Barbro N. Melgert, Jan H. von der Thusen, Bernt van den Blink, Rogier A. S. Hoek, Jelle R. Miedema, Stefan F. H. Neys, Odilia B. J. Corneth, Rudi W. Hendriks, Marlies S. Wijsenbeek, Mirjam Kool
Down-regulation of long non-coding RNA SNHG14 protects against acute lung injury induced by lipopolysaccharide through microRNA-34c-3p-dependent inhibition of WISP1
Jinyuan Zhu, Jijia Bai, Shaojin Wang, Hui Dong
Neutrophils from severe asthmatic patients induce epithelial to mesenchymal transition in healthy bronchial epithelial cells
Alexandre Haddad, Mellissa Gaudet, Maria Plesa, Zoulfia Allakhverdi, Andrea K. Mogas, Severine Audusseau, Carolyn J. Baglole, David H. Eidelman, Ronald Olivenstein, Mara S. Ludwig, Qutayba Hamid
What is the remaining status of adaptive servo-ventilation? The results of a real-life multicenter study (OTRLASV-study)
Dany Jaffuel, Carole Philippe, Claudio Rabec, Jean-Pierre Mallet, Marjolaine Georges, Stefania Redolfi, Alain Palot, Carey M. Suehs, Erika Nogue, Nicolas Molinari, Arnaud Bourdin
BMI is associated with FEV1 decline in chronic obstructive pulmonary disease: a meta-analysis of clinical trials
Yilan Sun, Stephen Milne, Jen Erh Jaw, Chen Xi Yang, Feng Xu, Xuan Li, Ma’en Obeidat, Don D. Sin
Treatment failure and hospital readmissions in severe COPD exacerbations treated with azithromycin versus placebo – a post-hoc analysis of the BACE randomized controlled trial
Kristina Vermeersch, Ann Belmans, Kris Bogaerts, Iwein Gyselinck, Nina Cardinaels, Maria Gabrovska, Joseph Aumann, Ingel K. Demedts, Jean-Louis Corhay, Eric Marchand, Hans Slabbynck, Christel Haenebalcke, Stefanie Vermeersch, Geert M. Verleden, Thierry Troosters, Vincent Ninane, Guy G. Brusselle, Wim Janssens, Vincent Ninane, Joseph Aumann, Ingel K. Demedts, Hans Slabbynck, Eric Marchand, Christel Haenebalcke, Rudi Peché, Guy G. Brusselle, Walter Vincken, Jean-Louis Corhay, Michiel Haerens, Antoine Fremault, Tine Lauwerier, Alix Debrock, Jan Lamont, Geert Tits, Paul Jordens, Alain Delobbe, Jean-Benoît Martinot
Efficacy of umeclidinium/vilanterol versus umeclidinium and salmeterol monotherapies in symptomatic patients with COPD not receiving inhaled corticosteroids: the EMAX randomised trial
François Maltais, Leif Bjermer, Edward M. Kerwin, Paul W. Jones, Michael L. Watkins, Lee Tombs, Ian P. Naya, Isabelle H. Boucot, David A. Lipson, Chris Compton, Mitra Vahdati-Bolouri, Claus F. Vogelmeier
Mesenchymal stromal cell conditioned media for lung disease: a systematic review and meta-analysis of preclinical studies
Chimobi Emukah, Evan Dittmar, Rija Naqvi, John Martinez, Alexis Corral, Axel Moreira, Alvaro Moreira
Isolation and characterization of extracellular vesicles from Broncho-alveolar lavage fluid: a review and comparison of different methods
Jonathan M. Carnino, Heedoo Lee, Yang Jin
Maintained therapeutic effect of revefenacin over 52 weeks in moderate to very severe Chronic Obstructive Pulmonary Disease (COPD)
James F. Donohue, Edward Kerwin, Sanjay Sethi, Brett Haumann, Srikanth Pendyala, Lorna Dean, Chris N. Barnes, Edmund J. Moran, Glenn Crater
Single-inhaler triple therapy in patients with chronic obstructive pulmonary disease: a systematic review
Sue Langham, Jen Lewis, Nick Pooley, Nina Embleton, Julia Langham, MeiLan K. Han, James D. Chalmers
Variable DNA methylation of aging-related genes is associated with male COPD
Xizi Du, Lin Yuan, Mengping Wu, Meichao Men, Ruoxi He, Leyuan Wang, Shuangyan Wu, Yang Xiang, Xiangping Qu, Huijun Liu, Xiaoqun Qin, Chengping Hu, Ling Qin, Chi Liu
Aberrant populations of circulating T follicular helper cells and regulatory B cells underlying idiopathic pulmonary fibrosis
Yuichiro Asai, Hirofumi Chiba, Hirotaka Nishikiori, Ryuta Kamekura, Hayato Yabe, Shun Kondo, Satsuki Miyajima, Katsunori Shigehara, Shingo Ichimiya, Hiroki Takahashi
Synthetic surfactant with a recombinant surfactant protein C analogue improves lung function and attenuates inflammation in a model of acute respiratory distress syndrome in adult rabbits
J. Zebialowicz Ahlström, F. Massaro, P. Mikolka, R. Feinstein, G. Perchiazzi, O. Basabe-Burgos, T. Curstedt, A. Larsson, J. Johansson, A. Rising
Unique patterns of lower respiratory tract microbiota are associated with inflammation and hospital mortality in acute respiratory distress syndrome
Michihito Kyo, Keisuke Nishioka, Takaaki Nakaya, Yoshiko Kida, Yuko Tanabe, Shinichiro Ohshimo, Nobuaki Shime
Chemical pleurodesis – a review of mechanisms involved in pleural space obliteration
Michal Mierzejewski, Piotr Korczynski, Rafal Krenke, Julius P. Janssen
Prognostic impact of tumor mutation burden and the mutation in KIAA1211 in small cell lung cancer
Mengting Zhou, Jun Fan, Zhenyu Li, Pindong Li, Yajie Sun, Yuhui Yang, Xiaoshu Zhou, Jing Wang, Ye Wang, Huiwei Qi, Weijing Cai, Xiaofang Dai, Fred R. Hirsch
YY1 mediates TGF-β1-induced EMT and pro-fibrogenesis in alveolar epithelial cells
Chuyi Zhang, Xiaoping Zhu, Yifei Hua, Qian Zhao, Kaijing Wang, Lixiao Zhen, Guangxue Wang, Jinhui Lü, An Luo, William C. Cho, Xin Lin, Zuoren Yu
Improved hemodynamics and cardiopulmonary function in patients with inoperable chronic thromboembolic pulmonary hypertension after balloon pulmonary angioplasty
Qi Jin, Qin Luo, Tao Yang, Qixian Zeng, Xue Yu, Lu Yan, Yi Zhang, Qing Zhao, Xiuping Ma, Chenhong An, Changming Xiong, Zhihui Zhao, Zhihong Liu
Effects of cigarette smoke on barrier function and tight junction proteins in the bronchial epithelium: protective role of cathelicidin LL-37
Miyoko Tatsuta, Keiko Kan-o, Yumiko Ishii, Norio Yamamoto, Tomohiro Ogawa, Satoru Fukuyama, Aimi Ogawa, Akitaka Fujita, Yoichi Nakanishi, Koichiro Matsumoto
Systemic inflammatory response to inhaled endotoxin does not correlate with airway response
Amika K. Sood, Allison J. Burbank, Michael Lawson, Haibo Zhou, Heather B. Wells, David B. Peden, Michelle L. Hernandez
Diagnostic test interpretation and referral delay in patients with interstitial lung disease
David Pritchard, Ayodeji Adegunsoye, Elyse Lafond, Janelle Vu Pugashetti, Ryan DiGeronimo, Noelle Boctor, Nandini Sarma, Isabella Pan, Mary Strek, Michael Kadoch, Jonathan H. Chung, Justin M. Oldham
The matrikine acetyl-proline-glycine-proline and clinical features of COPD: findings from SPIROMICS
J. Michael Wells, Dongqi Xing, Liliana Viera, Robert M. Burkes, Yixin Wu, Surya P. Bhatt, Mark T. Dransfield, David J. Couper, Wanda O’Neal, Eric A. Hoffman, Amit Gaggar, Igor Barjaktarevic, Jeffrey L. Curtis, Wassim W. Labaki, Mei Lan K. Han, Christine M. Freeman, Nirupama Putcha, Thomas Schlange, J. Edwin Blalock, Neil E. Alexis, Wayne H. Anderson, R. Graham Barr, Eugene R. Bleecker, Richard C. Boucher, Russell P. Bowler, Elizabeth E. Carretta, Stephanie A. Christenson, Alejandro P. Comellas, Christopher B. Cooper, David J. Couper, Gerard J. Criner, Ronald G. Crystal, Jeffrey L. Curtis, Claire M. Doerschuk, Mark T. Dransfield, Christine M. Freeman, Mei Lan K. Han, Nadia N. Hansel, Annette T. Hastie, Eric A. Hoffman, Robert J. Kaner, Richard E. Kanner, Eric C. Kleerup, Jerry A. Krishnan, Lisa M. LaVange, Stephen C. Lazarus, Fernando J. Martinez, Deborah A. Meyers, John D. Newell Jr, Elizabeth C. Oelsner, Wanda K. O’Neal, Robert Paine III, Nirupama Putcha, Stephen I. Rennard, Donald P. Tashkin, Mary Beth Scholand, J. Michael Wells, Robert A. Wise, Prescott G. Woodruff
Intra-tracheal administration of a naked plasmid expressing stromal derived factor-1 improves lung structure in rodents with experimental bronchopulmonary dysplasia
Kasonya Guerra, Carleene Bryan, Frederick Dapaah-Siakwan, Ibrahim Sammour, Shelly Drummond, Ronald Zambrano, Pingping Chen, Jian Huang, Mayank Sharma, Sebastian Shrager, Merline Benny, Shu Wu, Karen C. Young
Presentations and outcomes of interstitial lung disease and the anti-Ro52 autoantibody
A. Sclafani, K. M. D’Silva, B. P. Little, E. M. Miloslavsky, J. J. Locascio, A. Sharma, S. B. Montesi
The association of cognitive functioning as measured by the DemTect with functional and clinical characteristics of COPD: results from the COSYCONET cohort
Sarah Marietta von Siemens, Robert Perneczky, Claus F. Vogelmeier, Jürgen Behr, Diego Kauffmann-Guerrero, Peter Alter, Franziska C. Trudzinski, Robert Bals, Christian Grohé, Sandra Söhler, Benjamin Waschki, Johanna I. Lutter, Tobias Welte, Rudolf A. Jörres, Kathrin Kahnert, Stefan Andreas, Robert Bals, Jürgen Behr, Kathrin Kahnert, Burkhard Bewig, Roland Buhl, Ralf Ewert, Beate Stubbe, Manfred Gogol, Christian Grohé, Rainer Hauck, Matthias Held, Berthold Jany, Markus Henke, Felix Herth, Gerd Höffken, Hugo A. Katus, Anne-Marie Kirsten, Henrik Watz, Rembert Koczulla, Klaus Kenn, Juliane Kronsbein, Cornelia Kropf-Sanchen, Christoph Lange, Peter Zabel, Michael Pfeifer, Winfried J. Randerath, Werner Seeger, Michael Studnicka, Christian Taube, Helmut Teschler, Hartmut Timmermann, J. Christian Virchow, Claus Vogelmeier, Ulrich Wagner, Tobias Welte, Hubert Wirtz
The biomarkers suPAR and blood eosinophils are associated with hospital readmissions and mortality in asthma – a retrospective cohort study
K. E. J. Håkansson, Line J. H. Rasmussen, Nina S. Godtfredsen, Oliver D. Tupper, Jesper Eugen-Olsen, Thomas Kallemose, Ove Andersen, Charlotte Suppli Ulrik
Nasal epithelial cells to assess in vitro immune responses to respiratory virus infection in pregnant women with asthma
Rebecca L. Vanders, Alan Hsu, Peter G. Gibson, Vanessa E. Murphy, Peter A. B. Wark
Diverging effects of premature birth and bronchopulmonary dysplasia on exercise capacity and physical activity – a case control study
Katharina Ruf, Wolfgang Thomas, Maximilian Brunner, Christian P. Speer, Helge Hebestreit
Strategies for measuring airway mucus and mucins
Kalina R. Atanasova, Leah R. Reznikov
Primary pulmonary lymphoepithelioma-like carcinoma: a rare type of lung cancer with a favorable outcome in comparison to squamous carcinoma
Bojiang Chen, Xuping Chen, Ping Zhou, Lan Yang, Jing Ren, Xiaodong Yang, Weimin Li
Analysis of key clinical features for achieving complete remission in stage III and IV non-small cell lung cancer patients
Takuya Aoki, Takeshi Akiba, Jun Nishiyama, Sakurako Tajiri, Naoki Hayama, Genki Takahashi, Jun Tanaka, Masako Sato, Hiroto Takiguchi, Hiromi Tomomatsu, Katsuyoshi Tomomatsu, Takahisa Takihara, Kyoko Niimi, Tsuyoshi Oguma, Mitsutomo Kohno, Ryota Masuda, Tetsuya Urano, Hitoshi Itoh, Hiroshi Kajiwara, Naoya Nakamura, Etsuo Kunieda, Mitsunori Matsumae, Masayuki Iwazaki, Koichiro Asano
Accumulation of damaged mitochondria in alveolar macrophages with reduced OXPHOS related gene expression in IPF
Eliza Tsitoura, Eirini Vasarmidi, Eleni Bibaki, Athina Trachalaki, Chara Koutoulaki, George Papastratigakis, Sevasti Papadogiorgaki, George Chalepakis, Nikos Tzanakis, Katerina M. Antoniou
Metagenomic identification of severe pneumonia pathogens in mechanically-ventilated patients: a feasibility and clinical validity study
Libing Yang, Ghady Haidar, Haris Zia, Rachel Nettles, Shulin Qin, Xiaohong Wang, Faraaz Shah, Sarah F. Rapport, Themoula Charalampous, Barbara Methé, Adam Fitch, Alison Morris, Bryan J. McVerry, Justin O’Grady, Georgios D. Kitsios
Vitamin D deficiency exacerbates bleomycin-induced pulmonary fibrosis partially through aggravating TGF-β/Smad2/3-mediated epithelial-mesenchymal transition
Se-Ruo Li, Zhu-Xia Tan, Yuan-Hua Chen, Biao Hu, Cheng Zhang, Hua Wang, Hui Zhao, De-Xiang Xu
Electronic cigarette vapour increases virulence and inflammatory potential of respiratory pathogens
Deirdre F. Gilpin, Katie-Ann McGown, Kevin Gallagher, Jose Bengoechea, Amy Dumigan, Gisli Einarsson, J. Stuart Elborn, Michael M. Tunney
DNA methylation is associated with lung function in never smokers
Maaike de Vries, Ivana Nedeljkovic, Diana A. van der Plaat, Alexandra Zhernakova, Lies Lahousse, Guy G. Brusselle, Najaf Amin, Cornelia M. van Duijn, Judith M. Vonk, H. Marike Boezen
Relationship between diffusion capacity and small airway abnormality in COPDGene
Rachel N. Criner, Charles R. Hatt, Craig J. Galbán, Ella A. Kazerooni, David A. Lynch, Meredith C. McCormack, Richard Casaburi, Neil R. MacIntyre, Barry J. Make, Fernando J. Martinez, Wassim W. Labaki, Jeffrey L. Curtis, Mei Lan K. Han
Protein tyrosine kinase 2: a novel therapeutic target to overcome acquired EGFR-TKI resistance in non-small cell lung cancer
Xuexia Tong, Ryosuke Tanino, Rong Sun, Yukari Tsubata, Tamio Okimoto, Mayumi Takechi, Takeshi Isobe
Mortality risk and causes of death in patients with non-cystic fibrosis bronchiectasis
Sooim Sin, Seo Young Yun, Jee Min Kim, Chang Min Park, Jaeyoung Cho, Sun Mi Choi, Jinwoo Lee, Young Sik Park, Sang-Min Lee, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Chang-Hoon Lee
Dysbiosis of lower respiratory tract microbiome are associated with inflammation and microbial function variety
Kang-jie Li, Zi-long Chen, Yao Huang, Rui Zhang, Xiao-qian Luan, Ting-ting Lei, Ling Chen
Does a tailored intervention to promote adherence in patients with chronic lung disease affect exacerbations? A randomized controlled trial
Claudia Gregoriano, Thomas Dieterle, Anna-Lisa Breitenstein, Selina Dürr, Amanda Baum, Stéphanie Giezendanner, Sabrina Maier, Anne Leuppi-Taegtmeyer, Isabelle Arnet, Kurt E. Hersberger, Jörg D. Leuppi
Determination of rheology and surface tension of airway surface liquid: a review of clinical relevance and measurement techniques
Zhenglong Chen, Ming Zhong, Yuzhou Luo, Linhong Deng, Zhaoyan Hu, Yuanlin Song
Primary immunodeficiency-related bronchiectasis in adults: comparison with bronchiectasis of other etiologies in a French reference center
Hélène Goussault, Hélène Salvator, Emilie Catherinot, Marie-Laure Chabi, Colas Tcherakian, Alexandre Chabrol, Morgane Didier, Elisabeth Rivaud, Alain Fischer, Felipe Suarez, Olivier Hermine, Fanny Lanternier, Olivier Lortholary, Nizar Mahlaoui, Philippe Devillier, Louis-Jean Couderc
Excessive daytime sleepiness, metabolic syndrome, and obstructive sleep apnea: two independent large cross-sectional studies and one interventional study
Xinyi Li, Hengye Huang, Huajun Xu, Yue Shi, Yingjun Qian, Jianyin Zou, Hongliang Yi, Jian Guan, Shankai Yin
Inhaled corticosteroids and FEV1 decline in chronic obstructive pulmonary disease: a systematic review
Hannah R. Whittaker, Debbie Jarvis, Mohamed R. Sheikh, Steven J. Kiddle, Jennifer K. Quint
Impaired training-induced angiogenesis process with loss of pericyte-endothelium interactions is associated with an abnormal capillary remodelling in the skeletal muscle of COPD patients
Léo Blervaque, Emilie Passerieux, Pascal Pomiès, Matthias Catteau, Nelly Héraud, Marine Blaquière, François Bughin, Bronia Ayoub, Nicolas Molinari, Jean-Paul Cristol, Antonia Perez-Martin, Jacques Mercier, Maurice Hayot, Fares Gouzi
Serum bilirubin level is associated with exercise capacity and quality of life in chronic obstructive pulmonary disease
Ah Young Leem, Young Sam Kim, Ji-Hyun Lee, Tae-Hyung Kim, Ha Yan Kim, Yeon Mok Oh, Sang Do Lee, Ji Ye Jung
Threshold of the upper airway cross-section for hypopnea onset during sleep and its identification under waking condition
Hongyi Lin, Cunting Wang, Han Zhang, Huahui Xiong, Zheng Li, Xiaoqing Huang, Changjin Ji, Junfang Xian, Yaqi Huang
Targeted regulation of fibroblast state by CRISPR-mediated CEBPA expression
Wei Liu, Jeffrey A. Meridew, Aja Aravamudhan, Giovanni Ligresti, Daniel J. Tschumperlin, Qi Tan
Upregulation of MUC5AC by VEGF in human primary bronchial epithelial cells: implications for asthma
Sung-Ho Kim, Qing-Mei Pei, Ping Jiang, Juan Liu, Rong-Fei Sun, Xue-Jiao Qian, Jiang-Bo Liu
The clinical impact of drug-induced hepatotoxicity on anti-tuberculosis therapy: a case control study
Jin Hwa Song, Seo-Young Yoon, Tae Yun Park, Eun Young Heo, Deog Kyeom Kim, Hee Soon Chung, Jung-Kyu Lee
Comparative analyses of long non-coding RNA profiles in vivo in cystic fibrosis lung airway and parenchyma tissues
Parameet Kumar, Chaitali Sen, Kathryn Peters, Raymond A. Frizzell, Roopa Biswas
Exchange protein directly activated by cAMP (Epac) protects against airway inflammation and airway remodeling in asthmatic mice
Yi-fei Chen, Ge Huang, Yi-min Wang, Ming Cheng, Fang-fang Zhu, Jin-nan Zhong, Ya-dong Gao
Clinical characteristics and treatment outcomes of patients with macrolide-resistant Mycobacterium avium complex pulmonary disease: a systematic review and meta-analysis
Youngmok Park, Eun Hye Lee, Inkyung Jung, Goeun Park, Young Ae Kang
Prognostic differences among patients with idiopathic interstitial pneumonias with acute exacerbation of varying pathogenesis: a retrospective study
Motoyasu Kato, Tomoko Yamada, Shunichi Kataoka, Yuta Arai, Keita Miura, Yusuke Ochi, Hiroaki Ihara, Ryo Koyama, Shinichi Sasaki, Kazuhisa Takahashi
Effects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-induced responses in patients with mild asthma: a double-blind, randomised, parallel-group study
Brian R. Leaker, Dave Singh, Sam Lindgren, Gun Almqvist, Leif Eriksson, Barbara Young, Brian O’Connor
The effectiveness of Reslizumab in severe asthma treatment: a real-world experience
H. Ibrahim, R. O’Sullivan, D. Casey, J. Murphy, J. MacSharry, B. J. Plant, D. M. Murphy
Gene therapy-emulating small molecule treatments in cystic fibrosis airway epithelial cells and patients
Q. Yang, A. R. Soltis, G. Sukumar, X. Zhang, H. Caohuy, J. Freedy, C. L. Dalgard, M. D. Wilkerson, H. B. Pollard, B. S. Pollard
The socioeconomic burden of chronic lung disease in low-resource settings across the globe – an observational FRESH AIR study
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