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Pulmonary Emphysema 

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  1. Open Access 01-12-2024 | Idiopathic Pulmonary Fibrosis | OriginalPaper

    A formula for predicting emphysema extent in combined idiopathic pulmonary fibrosis and emphysema

    Idiopathic pulmonary fibrosis (IPF) is a progressive and debilitating lung disease [ 1 , 2 ]. Emphysema, where the alveoli are damaged and grossly enlarged, is present in approximately 30–40% of patients with IPF [ 3 , 4 ]. Patients with IPF and …

  2. 10-11-2023 | Chronic Obstructive Lung Disease | OriginalPaper

    Dietary tannic acid attenuates elastase-induced pulmonary inflammation and emphysema in mice

    Emphysema is one of the major components of chronic obstructive pulmonary disease (COPD), which is characterised by the destruction and enlargement of air spaces, leading to airflow limitation and dyspnoea, finally progressing to oxygen …

  3. 16-01-2024 | Pulmonary Emphysema | Online First

    Alpha-7 Nicotinic Receptor Agonist Protects Mice Against Pulmonary Emphysema Induced by Elastase

    Pulmonary emphysema is a primary component of chronic obstructive pulmonary disease (COPD), a life-threatening disorder characterized by lung inflammation and restricted airflow, primarily resulting from the destruction of small airways and …

  4. Open Access 01-12-2023 | Pulmonary Hypertension | OriginalPaper

    An increased risk of pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema: a meta-analysis

    The concept of combined fibrosis and emphysema was first proposed by Mallory in 1984. It is characterized by predominant emphysema in the upper lobes and pulmonary fibrosis in the lower lobes [ 1 ]. The most common fibrotic pattern in combined …

  5. 15-08-2023 | Pulmonary Emphysema | OriginalPaper

    The influence of image reconstruction methods on the diagnosis of pulmonary emphysema with convolutional neural network

    This study investigated the influence of iterative reconstruction (IR) methods on computed tomography (CT) images when training convolutional neural network (CNN) models to diagnose pulmonary emphysema. To evaluate the influence of the IR …

  6. Open Access 01-12-2022 | Pulmonary Hypertension | OriginalPaper

    Use of machine learning models to predict prognosis of combined pulmonary fibrosis and emphysema in a Chinese population

    Pulmonary interstitial fibrosis and emphysema are two distinct clinical entities with different pathogeneses and pathophysiologic manifestations. However, an increasing number of studies consider that the two phenotypes can coexist within one …

  7. 01-12-2021 | Idiopathic Pulmonary Fibrosis | Report

    Prognostic Significance of Pulmonary Artery to Aorta Ratio and Other CT Markers in Pulmonary Fibrosis With and Without Emphysema

    Pulmonary hypertension (PH) is associated with decreased survival in patients with pulmonary fibrosis and combined pulmonary fibrosis and emphysema. Main pulmonary artery (PA) diameter and PA diameter/ascending aortic diameter (PA/AA) ratio, as …

  8. Open Access 01-02-2022 | Idiopathic Pulmonary Fibrosis | OriginalPaper

    Clinical Outcomes of Patients with Combined Idiopathic Pulmonary Fibrosis and Emphysema in the IPF-PRO Registry

    Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease associated with progressive decline in lung function, debilitating symptoms, and high mortality [ 1 ]. Emphysema is a common comorbidity in patients with IPF [ 2 ], but the …

  9. Open Access 01-12-2021 | Idiopathic Pulmonary Fibrosis | OriginalPaper

    Development of a nomogram for predicting the presence of combined pulmonary fibrosis and emphysema

    Pulmonary interstitial fibrosis and emphysema have long been perceived as two separate diseases. Interstitial lung diseases (ILD) encompass a large and heterogeneous group of diffuse parenchymal lung disorders characterized by distinct forms and …

  10. Open Access 01-12-2020 | Bronchiectasis | OriginalPaper

    Differentiating combined pulmonary fibrosis and emphysema from pure emphysema: utility of late gadolinium-enhanced MRI

    Late gadolinium-enhanced magnetic resonance imaging (LGE-MRI) can differentiate combined pulmonary fibrosis and emphysema from pure emphysema. LGE-MRI is not as accurate as high-resolution computed tomography (HRCT) in characterising reticulation …

  11. 01-12-2021 | Systemic Sclerosis

    Effect of combined pulmonary fibrosis and emphysema on patients with connective tissue diseases and systemic sclerosis: a systematic review and meta-analysis

    Interstitial lung disease (ILD) is characterized by fibrotic features generally in the lung bases of patients with connective tissue diseases (CTDs), such as rheumatoid arthritis (RA) and systemic sclerosis (SSc), observed on chest computed …

  12. Open Access 26-04-2023 | Pulmonary Emphysema | OriginalPaper

    Can the size of the contact area body-ground influence the presence of acute pulmonary emphysema in cases of incomplete hanging?

    In a recently published study, we showed that acute pulmonary emphysema (APE) was present in cases of death by incomplete hanging and absent in cases of complete hanging. This result suggested a possible role of the hanging position on the …

  13. 01-12-2020 | Pulmonary Emphysema | Original Research

    Risk factors associated with the detection of pulmonary emphysema in older asymptomatic respiratory subjects

    Aging is a normal biological process associated with multiple anatomic and functional abnormalities and morbidities. The physiological effects of aging in the lungs include, among others, a progressive decrease in forced vital capacity with an …

  14. 01-12-2020 | Isoniazid | Original Research

    Impact of emphysema on sputum culture conversion in male patients with pulmonary tuberculosis: a retrospective analysis

    About 10 million people were newly diagnosed with active tuberculosis (TB) and 1.2 million patients died in 2018 [ 1 ]. TB clinical features are complicated by bacterial aspects, including drug-resistant Mycobacterium tuberculosis (MTB), and …

  15. 01-08-2020 | SARS-CoV-2 | BriefCommunication

    SARS-CoV-2 pulmonary infection revealed by subcutaneous emphysema and pneumomediastinum

  16. 01-12-2020 | Idiopathic Pulmonary Fibrosis | Original Research

    Prognosis of patients with acute exacerbation of combined pulmonary fibrosis and emphysema: a retrospective single-centre study

    Combined pulmonary fibrosis and emphysema (CPFE) is characterised by emphysema in the upper lung and fibrosis in the lower lung on chest high-resolution computed tomography (CT) [ 1 ]. Previous analyses of CPFE cohorts have provided conflicting …

  17. Open Access 01-03-2023 | Lung Cancer | OriginalPaper

    Pulmonary emphysema and coronary artery calcifications at baseline LDCT and long-term mortality in smokers and former smokers of the ITALUNG screening trial

    Cardio-vascular disease (CVD), lung cancer (LC), and respiratory diseases are the three main causes of death in smokers and former smokers undergoing low-dose computed tomography (LDCT) for LC screening [ 1 – 4 ]. The latter is currently …

  18. Open Access 01-12-2019 | Idiopathic Pulmonary Fibrosis | OriginalPaper

    Combined pulmonary fibrosis and emphysema and idiopathic pulmonary fibrosis in non-small cell lung cancer: impact on survival and acute exacerbation

    Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing interstitial pneumonia, characterized by progressively worsening dyspnea and lung function, and is associated with a poor prognosis [ 1 ]. IPF is reportedly associated with an …

  19. Open Access 01-12-2019 | Chronic Obstructive Lung Disease | OriginalPaper

    PD-L1, FGFR1, PIK3CA, PTEN, and p16 expression in pulmonary emphysema and chronic obstructive pulmonary disease with resected lung squamous cell carcinoma

    Lung cancer is the primary cause of cancer-related death worldwide. It is well known that smoking is a major risk factor for lung cancer [ 1 ]. Smoking causes emphysema and chronic obstructive pulmonary disease (COPD) [ 2 , 3 ]. Several studies …

  20. Open Access 01-12-2019 | Pulmonary Emphysema | OriginalPaper

    Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers

    Cigarette smoking is the most important risk factor for the development of chronic obstructive pulmonary disease (COPD) in the developed world and is a major cause of premature morbidity and mortality [ 1 ]. Comorbidities associated with COPD, such …

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