Top

Respiratory Research

Published in:

Open Access 01-12-2019 | Chronic Obstructive Lung Disease | Research

Effects of use of an eHealth platform e-Vita for COPD patients on disease specific quality of life domains

Authors: Esther P.W.A. Talboom-Kamp, Marije S. Holstege, Niels H. Chavannes, Marise J. Kasteleyn

Published in: Respiratory Research | Issue 1/2019

Abstract

Background

Integrated disease management with self-management for Chronic Obstructive Pulmonary Disease (COPD) is effective to improve clinical outcomes. eHealth can improve patients’ involvement to be able to accept and maintain a healthier lifestyle. Eventhough there is mixed evidence of the impact of eHealth on quality of life (QoL) in different settings.

Aim

The primary aim of the e-Vita-COPD-study was to investigate the effect of use of eHealth patient platforms on disease specific QoL of COPD patients.

Methods

We evaluated the impact of an eHealth platform on disease specific QoL measured with the clinical COPD questionnaire (CCQ), including subscales of symptoms, functional state and mental state. Interrupted time series (ITS) design was used to collect CCQ data at multiple time points. Multilevel linear regression modelling was used to compare trends in CCQ before and after the intervention.

Results

Of 742 invited COPD patients, 244 signed informed consent. For the analyses, we only included patients who actually used the eHealth platform (n = 123). The decrease of CCQ-symptoms was 0.20% before the intervention and 0.27% after the intervention; this difference in slopes was statistically significant (P = 0.027). The decrease of CCQ-mental was 0.97% before the intervention and after the intervention there was an increase of 0.017%; this difference was statistically significant (P = 0.01). No significant difference was found in the slopes of CCQ (P = 0.12) and CCQ-function (P = 0.11) before and after the intervention.

Conclusion

The e-Vita eHealth platform had a potential beneficial impact on the CCQ-symptoms of COPD patients, but not on functional state. The CCQ-mental state remained stable after the intervention, but this was a deterioration compared to the improving situation before the start of the eHealth platform. Therefore, health care providers should be aware that, although symptoms improve, there might be a slight increase in anxiety and depression after introducing an eHealth intervention to support self-management.

Trial registration

Our study is registered in the Dutch Trial Register (national registration of clinical trails, mandatory for publication) with number NTR4098 and can be found at http://www.trialregister.nl/trial/3936.

Date registered: 2013-07-31.

First participant: 2014-01-01.

Available only for authorised users

Epping-Jordan J, Bengoa R, Kawar R, et al. The challenge of chronic conditions: WHO responds. BMJ. 2001;323(7319):947–8 published Online First: 2001/10/27.CrossRef

Boriani G, Diemberger I, Ziacchi M, et al. AF burden is important - fact or fiction? Int J Clin Pract. 2014;68(4):444–52. https://doi.org/10.1111/ijcp.12326 published Online First: 2014/02/07.CrossRefPubMed

Go AS, Hylek EM, Phillips KA, et al. Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and risk factors in atrial fibrillation (ATRIA) study. JAMA. 2001;285(18):2370–5 [published Online First: 2001/05/10].CrossRef

Heit JA. Venous thromboembolism: disease burden, outcomes and risk factors. J Thromb Haemost. 2005;3(8):1611–7. https://doi.org/10.1111/j.1538-7836.2005.01415.x [published Online First: 2005/08/17].CrossRefPubMed

Lopez-Campos JL, Tan W, Soriano JB. Global burden of COPD. Respirology. 2016;21(1):14–23. https://doi.org/10.1111/resp.12660 [published Online First: 2015/10/24].CrossRefPubMed

Ruppert A, Steinle T, Lees M. Economic burden of venous thromboembolism: a systematic review. J Med Econ. 2011;14(1):65–74. https://doi.org/10.3111/13696998.2010.546465 [published Online First: 2011/01/13].CrossRefPubMed

Talboom-Kamp EP, Verdijk NA, Blom CM, et al. E-Vita: design of an innovative approach to COPD disease management in primary care through eHealth application. BMC Pulm Med. 2016;16(1):121. https://doi.org/10.1186/s12890-016-0282-5 [published Online First: 2016/08/18].CrossRefPubMedPubMedCentral

Finkelstein J, Friedman RH. Potential role of telecommunication technologies in the management of chronic health conditions. Dis Manag Health Out. 2000;8:57–63. https://doi.org/10.2165/00115677-200008020-00001.CrossRef

Pare G, Jaana M, Sicotte C. Systematic review of home telemonitoring for chronic diseases: the evidence base. J Am Med Inform Assoc. 2007;14(3):269–77. https://doi.org/10.1197/jamia.M2270 [published Online First: 2007/03/03].CrossRefPubMedPubMedCentral

10.

Diaz-Guzman E, Mannino DM. Epidemiology and prevalence of chronic obstructive pulmonary disease. Clin Chest Med. 2014;35(1):7–16. https://doi.org/10.1016/j.ccm.2013.10.002 [published Online First: 2014/02/11].CrossRefPubMed

11.

Boezen HM, Postma DS, Poos MJJC. Hoe vaak komt COPD voor en hoeveel mensen sterven eraan? [What is the prevalence and mortalityof COPD?]. Volksgezondheid Toekomst Verkenning, Nationaal Kompas Volksgezondheid. Bilthoven: RIVM; 2013.

12.

World Health Organisation. Chronic obstructive pulmonary disease (COPD) Fact sheet N°315 2017 [Available from: http://www.who.int/mediacentre/factsheets/fs315/en/. Accessed 22 Feb 2019. 2019

13.

World Health Organisation. Chronic respiratory diseases - COPD management [Accessed 13 July 2019]. 2019.

14.

Effing T, van der Palen J, Frith P. Education in COPD self-management: only part of the game. Respirology. 2014;19(2):151–2. https://doi.org/10.1111/resp.12231 [published Online First: 2014/01/01].CrossRefPubMed

15.

Kruis AL, Smidt N, Assendelft WJ, et al. Cochrane corner: is integrated disease management for patients with COPD effective? Thorax. 2014;69(11):1053–5. https://doi.org/10.1136/thoraxjnl-2013-204974 [published Online First: 2014/01/15].CrossRefPubMedPubMedCentral

16.

Effing T, Kerstjens H, van der Valk P, et al. (Cost)-effectiveness of self-treatment of exacerbations on the severity of exacerbations in patients with COPD: the COPE II study. Thorax. 2009;64(11):956–62. https://doi.org/10.1136/thx.2008.112243 [published Online First: 2009/09/09].CrossRefPubMed

17.

Bourbeau J, Collet JP, Schwartzman K, et al. Economic benefits of self-management education in COPD. Chest. 2006;130(6):1704–11. https://doi.org/10.1378/chest.130.6.1704 [published Online First: 2006/12/15].CrossRefPubMed

18.

Kruis AL, Boland MR, Assendelft WJ, et al. Effectiveness of integrated disease management for primary care chronic obstructive pulmonary disease patients: results of cluster randomised trial. BMJ. 2014;349:g5392. https://doi.org/10.1136/bmj.g5392 [published Online First: 2014/09/12].CrossRefPubMedPubMedCentral

19.

Talboom-Kamp EP, Verdijk NA, Kasteleyn MJ, et al. The effect of integration of self-management web platforms on health status in chronic obstructive pulmonary disease Management in Primary Care (e-Vita study): interrupted time series design. J Med Internet Res. 2017;19(8):e291. https://doi.org/10.2196/jmir.8262 [published Online First: 2017/08/18].CrossRefPubMedPubMedCentral

20.

Snoeck-Stroband JB, Schermer TRJ, Van Schayck CP, et al. NHG-Standaard COPD (Derde herziening). Huisarts Wet. 2015;58(4):198–2011.

21.

van der Molen T, Willemse BW, Schokker S, et al. Development, validity and responsiveness of the clinical COPD questionnaire. Health Qual Life Outcomes. 2003;1:13 published Online First: 2003/05/30.CrossRef

22.

Cochrane. Cochrane Effective Practice and Organisation of Care (EPOC). Interrupted time series (ITS) analyses. EPOC Resources for review authors. 2017 [Available from: http://epoc.cochrane.org/epoc-specific-resources-review-authors Accessed 22 Feb 2019.

23.

In ‘t Veen H, Mennema B, van Noort E. Online self-management in COPD or asthma: with or without the healthcare provider? Eur Respir J. 2012;40(suppl 56):237.

24.

van Vugt M, de Wit M, Sieverink F, et al. Uptake and effects of the e-Vita personal health record with self-management support and coaching, for type 2 diabetes patients treated in primary care. J Diabetes Res. 2016;2016:5027356. https://doi.org/10.1155/2016/5027356 published Online First: 2016/03/10.CrossRefPubMedPubMedCentral

25.

Sieverink F, Kelders SM, Braakman-Jansen LM, et al. The added value of log file analyses of the use of a personal health record for patients with type 2 diabetes mellitus: preliminary results. J Diabetes Sci Technol. 2014;8(2):247–55. https://doi.org/10.1177/1932296814525696 [published Online First: 2014/05/31].CrossRefPubMedPubMedCentral

26.

Alma H, de Jong C, Jelusic D, et al. Health status instruments for patients with COPD in pulmonary rehabilitation: defining a minimal clinically important difference. NPJ Prim Care Respir Med. 2016;26:16041. https://doi.org/10.1038/npjpcrm.2016.41 published Online First: 2016/09/07.CrossRefPubMedPubMedCentral

27.

Tsiligianni I, Kocks J, Tzanakis N, et al. Factors that influence disease-specific quality of life or health status in patients with COPD: a review and meta-analysis of Pearson correlations. Prim Care Respir J. 2011;20(3):257–68. https://doi.org/10.4104/pcrj.2011.00029 [published Online First: 2011/04/08].CrossRefPubMed

28.

Yohannes AM, Alexopoulos GS. Depression and anxiety in patients with COPD. Eur Respir Rev. 2014;23(133):345–9. https://doi.org/10.1183/09059180.00007813 published Online First: 2014/09/02.CrossRefPubMedPubMedCentral

29.

Trappenburg JC, Monninkhof EM, Bourbeau J, et al. Effect of an action plan with ongoing support by a case manager on exacerbation-related outcome in patients with COPD: a multicentre randomised controlled trial. Thorax. 2011;66(11):977–84. https://doi.org/10.1136/thoraxjnl-2011-200071 published Online First: 2011/07/26.CrossRefPubMed

30.

Effing T, Zielhuis G, Kerstjens H, et al. Community based physiotherapeutic exercise in COPD self-management: a randomised controlled trial. Respir Med. 2011;105(3):418–26. https://doi.org/10.1016/j.rmed.2010.09.017 published Online First: 2010/10/19.CrossRefPubMed

31.

Miravitlles M, Anzueto A, Legnani D, et al. Patient’s perception of exacerbations of COPD--the PERCEIVE study. Respir Med. 2007;101(3):453–60. https://doi.org/10.1016/j.rmed.2006.07.010 published Online First: 2006/08/30.CrossRefPubMed

32.

Ahmed S, Ernst P, Bartlett SJ, et al. The effectiveness of web-based asthma self-management system, my asthma portal (MAP): a pilot randomized controlled trial. J Med Internet Res. 2016;18(12):e313. https://doi.org/10.2196/jmir.5866 published Online First: 2016/12/03.CrossRefPubMedPubMedCentral

33.

Eysenbach G. The law of attrition. J Med Internet Res. 2005;7(1):e11. https://doi.org/10.2196/jmir.7.1.e11 [published Online First: 2005/04/15].CrossRefPubMedPubMedCentral

34.

Nijland N, Gemert van-Pijnen JEWC, Kelders SM, et al. Factors influencing the use of a web-based application for supporting the self- care of patients with type 2 diabetes: a longitudinal study. J Med Internet Res. 2011;13:e71. https://doi.org/10.2196/jmir.1603 [published Online First: 2011/09/30].CrossRefPubMedPubMedCentral

35.

Greenwood DA, Young HM, Quinn CC. Telehealth remote monitoring systematic review; structured self-monitoring of blood glucose and impact on A1C. J Diabetes Sci Technol. 2014;8. https://doi.org/10.1177/1932296813519311 [published Online First: 2014/02/21].CrossRef

36.

Wilson K, Bell C, Wilson L, et al. Agile research to complement agile development: a proposal for an mHealth research lifecycle. Npj Digit Med. 2018;1:46 [published Online First: 2018/09/13].CrossRef

Title: Effects of use of an eHealth platform e-Vita for COPD patients on disease specific quality of life domains
Authors: Esther P.W.A. Talboom-Kamp
Marije S. Holstege
Niels H. Chavannes
Marise J. Kasteleyn
Publication date: 01-12-2019
Publisher: BioMed Central
Keyword: Chronic Obstructive Lung Disease
Published in: Respiratory Research / Issue 1/2019
Electronic ISSN: 1465-993X
DOI: https://doi.org/10.1186/s12931-019-1110-2

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin

Prof. Florian Limbourg

Prof. Anoop Chauhan

Developed by: Springer Medicine

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Aim

Methods

Results

Conclusion

Trial registration

Please log in to get access to this content

Other articles of this Issue 1/2019

Comparative analyses of long non-coding RNA profiles in vivo in cystic fibrosis lung airway and parenchyma tissues

Biomarkers of collagen synthesis predict progression in the PROFILE idiopathic pulmonary fibrosis cohort

Prognostic differences among patients with idiopathic interstitial pneumonias with acute exacerbation of varying pathogenesis: a retrospective study

AGER expression and alternative splicing in bronchial biopsies of smokers and never smokers

Imaging-based clusters in former smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and intermediate outcome measures in COPD study (SPIROMICS)

Psychometric properties and minimal important differences of SF-36 in Idiopathic Pulmonary Fibrosis

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

At a glance: The STEP trials