Reactions Weekly 1/2019

Graft-Versus-Host Disease News item

Health Canada: potential risk with unauthorised cell therapies

Liver Transplantation News item

Hepatotoxicity with tocilizumab: Canadian and NZ warnings

Eclampsia News item

Magnesium sulfate: neonatal skeletal AEs with in utero exposure

News item

MHRA seeks help in reversing decline in Yellow Card reports

Cough Correspondence

PMDA warning of serious lung disease with Verzenio

News item

PRAC recommends withdrawing MAAs for fenspiride in EU

Hormonal Replacement Therapy News item

Tofacitinib restrictions in place while EU review underway

Insulins News item

US FDA warns of unauthorised devices for diabetes control

Etanercept Clinical study

Infections with bDMARDs and glucocorticoids before arthroplasty

Naloxone Clinical study

Opioid-related fatal overdoses vary with naloxone access laws

Opportunistic Infection Clinical study

Opportunistic infections with ibrutinib

Breast Cancer Case report

Abemaciclib

Isoniazid Case report

Adalimumab

Joint Pain Case report

Adalimumab

Lung Cancer Case report

Adalimumab

Adalimumab Case report

Adalimumab

Nausea Case report

Alectinib

Multiple Sclerosis Case report

Alemtuzumab

Propranolol Case report

Aloin/atropine/cathine/diazepam/liothyronine

Panic Disorder Case report

Alprazolam/paroxetine

Alteplase Case report

Alteplase

Ventricular Tachycardia Case report

Amiodarone

Suicide Case report

Amlodipine/benazepril overdose

Timolol Case report

Amoxicillin/clavulanic acid/digoxin/warfarin interaction

Tuberculosis Case report

Amphotericin-B/ethambutol/pyrazinamide

Heart Failure Case report

Anthracyclines/trastuzumab

Rib Fracture Case report

Anti-digoxin polyclonal antibody/digoxin

Vasculitis Case report

Anti-TB drugs

Dabigatran Case report

Anticoagulants/antiplatelets

Antiepileptic Drugs Case report

Antiepileptics

Tuberculosis Case report

Antihypertensives/rifampicin interaction

Lymphoma Case report

Antineoplastics

Lymphoma Case report

Antineoplastics

Lymphoma Case report

Antineoplastics

Rituximab Case report

Antineoplastics

Tocilizumab Case report

Antineoplastics

Lymphoma Case report

Antineoplastics

Metastasis Case report

Antineoplastics

Septicemia Case report

Antineoplastics

Methotrexate Case report

Antineoplastics

Esophagitis Case report

Antineoplastics/folinic acid

Kidney Injury Case report

Antineoplastics/loxoprofen

Post-Exposure Prophylaxis Case report

Antiretrovirals

Hepatitis B Case report

Antivirals

Dystonia Case report

Aripiprazole/penicillamine

Sinus Surgery Case report

Aspirin

Erythema Nodosum Case report

Aspirin

Compartment Syndrome Case report

Aspirin overdose

Tirofiban Case report

Aspirin/heparin/prasugrel

Case report

Atezolizumab

Ticagrelor Case report

Atorvastatin/ticagrelor interaction

Anaphylaxis Case report

Atracurium besilate/epinephrine

Diarrhea Case report

Atropine

Intoxication Case report

Atropine/pralidoxime chloride

Axitinib Case report

Axitinib/pazopanib/sunitinib

Acute Myeloid Leukemia Case report

Azacitidine/unspecified intrathecal chemotherapy

Azathioprine Case report

Azathioprine

Azathioprine Case report

Azathioprine/prednisolone/tacrolimus

Dystonia Case report

Baclofen

Eating Disorder Case report

Baclofen overdose

Graft-Versus-Host Disease Case report

Basiliximab/immune globulin/tacrolimus

Tuberculosis Case report

Bedaquiline/delamanid

Tachyarrythmia Case report

Benzylpenicillin

Multiple Sclerosis Case report

Biotin

Myalgie Case report

Bortezomib/dexamethasone

Shingles Case report

Brivudine/capecitabine interaction

Foreign Body Aspiration Case report

Bromazepam/hexoprenaline

Laparotomy Case report

Bupivacaine

Laminectomy Case report

Bupivacaine/hydromorphone

Morphine Case report

Bupivacaine/hydromorphone/morphine

Tachyarrythmia Case report

Bupropion overdose

Cardiogenic Shock Case report

Bupropion/escitalopram

Status Epilepticus Case report

Bupropion/fentanyl

Tremor Case report

Bupropion/paroxetine

Cabergoline Case report

Cabergoline/pasireotide

Hyperparathyroidism Case report

Calcitriol/calcium carbonate

Metabolic Acidosis Case report

Calcium carbonate/oxytocin

Metabolic Acidosis Case report

Canagliflozin/metformin toxicity

Mutism Case report

Capecitabine

Splenectomy Case report

Capecitabine/oxaliplatin

Trigeminal Neuralgia Case report

Carbamazepine/rivaroxaban interaction

Nausea Case report

Carboplatin/cyclophosphamide/paclitaxel

Cranial MRI Case report

Carboplatin/etoposide/melphalan

Peritoneal Cancer Case report

Carboplatin/paclitaxel

Cefepime Case report

Cefepime

Chloroquin Case report

Chloroquine/hydroxychloroquine

Diseases of the neuromuscular synapses and muscles Case report

Ciclosporin

Vasculitis Case report

Ciclosporin/prednisone

Leukopenia Case report

Cisplatin/docetaxel/fluorouracil

Rituximab Case report

Cladribine/rituximab/vemurafenib

Chickenpox Case report

Clindamycin

In Vitro Fertilisation Case report

Clomifene

Clonidine Case report

Clonidine/naloxone

Acute Kidney Injury Case report

Clozapine/lithium

Autopsy Case report

Clozapine/pipamperone

Schizophrenia Case report

Clozapine/risperidone

Schizophrenia Case report

Clozapine/risperidone interactions

Acute Kidney Injury Case report

Colistin

Clostridium Case report

Collagenase clostridium histolyticum

Spironolactone Case report

Cortisone/rituximab

Cough Case report

Cotrimoxazole

Crizotinib Case report

Crizotinib

NSCLC Case report

Crizotinib

Multiple Myeloma Case report

Cyclophosphamide/epirubicin/fluorouracil

Neuropathic Pain Case report

Cyclophosphamide/thalidomide

Case report

Cynara-scolymus

Tachyarrythmia Case report

Cyproheptadine overdose

Lymphoma Case report

Cytarabine

Acute Myeloid Leukemia Case report

Cytarabine

Bisoprolol Case report

Dabigatran etexilate

Cerebral Sinus Venous Thrombosis Case report

Dabigatran etexilate/heparin/idarucizumab

Everolimus Case report

Dabrafenib/everolimus/trametinib

Liver Transplantation Case report

Daclizumab/tizanidine

Dapagliflozin Case report

Dapagliflozin/metformin/empagliflozin

Pneumonia Case report

Daptomycin

Agranulocytosis Case report

Dasatinib

Case report

Defibrotide/thrombomodulin-alfa

Hyperparathyroidism Case report

Denosumab

Hypocalcemia Case report

Denosumab

Pneumonia Case report

Denosumab

Femoral Hernia Case report

Desflurane/propofol/rocuronium bromide interaction

Insulins Case report

Dexamethasone/hydrocortisone

Amphotericin B Case report

Diclofenac/hydroxychloroquine/steroids

Paracetamol Case report

Diclofenac/paracetamol

Addiction Case report

Dihydrocodeine/dihydrocodeine/paracetamol/codeine phosphate

Shock Case report

Diltiazem/flecainide

Multiple Sclerosis Case report

Dimethyl fumarate

Multiple Sclerosis Case report

Dimethyl fumarate

Diphenhydramine Case report

Diphenhydramine overdose

Infliximab Case report

Disease modifying antirheumatics

Myocardial Infarction Case report

Dobutamine/dopamine

Cyanosis Case report

Dobutamine/dopamine/milrinone

Hemofiltration Case report

Dopamine/methylprednisolone/ulinastatin

Pancreatitis Case report

Drospirenone/ethinylestradiol/gemfibrozil

Acute Kidney Injury Case report

Duloxetine

Case report

Efavirenz

Prednisolone Case report

Eftrenonacog-alfa

Stroke Case report

Emicizumab/recombinant factor-VIIa

Gastrointestinal Bleeding Case report

Enoxaparin sodium/fondaparinux sodium/heparin

Enoxaparin Case report

Enoxaparin-sodium

Acenocoumarol Case report

Enoxaparin-sodium

Glomerulonephritis Case report

Enoxaparin-sodium

Ventricular Tachycardia Case report

Epinephrine

Urinary Incontinence Case report

Ertapenem

Etoricoxib Case report

Etoricoxib

Acute Kidney Injury Case report

Etoricoxib

Nephrectomy Case report

Everolimus

Von Willebrand Disease Case report

Factor-VIII/Von-Willebrand factor

Felodipine Case report

Felodipine

Opioids Case report

Fentanyl

Nausea Case report

Ferrous-sulfate

Pleural Effusion Case report

Flecainide overdose

Hypotension Case report

Flecainide overdose

Leukopenia Case report

Fluorouracil/mitomycin

Suicide Case report

Fluvoxamine overdose

Magnetic Resonance Cholangio Pancreatography Case report

Fulvestrant

Insulins Case report

Furosemide

Omeprazole Case report

Furosemide/omeprazole

Case report

Ganciclovir/valganciclovir

Case report

Gelatin/polyvinyl alcohol

Case report

Gemcitabine

Nephrectomy Case report

General anaesthetics

Platelet Aggregation Inhibitor Case report

Ginkgo biloba

Ultrasound Case report

Goserelin

Heparin Case report

Heparin

Phenprocoumon Case report

Heparin/phenprocoumon/rivaroxaban

Ticagrelor Case report

Heparin/ticagrelor

Vomiting Case report

Hydrogen peroxide

Methylnaltrexone Case report

Hydromorphone/methadone/methylnaltrexone bromide

Headache Case report

Hydroxychloroquine

Diseases of the neuromuscular synapses and muscles Case report

Hydroxychloroquine

Myocarditis Case report

Ibrutinib

Imatinib Case report

Imatinib

Micafungin Case report

Immunosuppressants

Tacrolimus Case report

Immunosuppressants

Micafungin Case report

Immunosuppressants

Levofloxacin Case report

Immunosuppressants

Infertility Case report

Immunosuppressants

Infliximab Case report

Infliximab

Infliximab Case report

Infliximab

Infliximab Case report

Infliximab

Influenza Virus Case report

Influenza virus vaccine

Insulin Glargine Case report

Insulin glargine/insulin lispro

Ribavirin Case report

Interferon/ribavirin

Melanoma Case report

Ipilimumab

Iron Deficiency Case report

Iron isomaltoside 1000

Isoniazid Case report

Isoniazid

Isoniazid Case report

Isoniazid

Lansoprazole Case report

Isotretinoin

Naproxen Case report

Ketamine

Cystitis Case report

Ketamine abuse

Metabolic Acidosis Case report

Lacosamide overdose

Lamotrigine Case report

Lamotrigine/lithium

Premature Ejaculation Case report

Ledipasvir/sofosbuvir

Thoracic Pain Case report

Lenalidomide

Hypersensitivity Pneumonitis Case report

Lenalidomide

Joint Pain Case report

Letrozole

Fertility Case report

Leuprorelin

Torticollis Spasticus Case report

Levodopa/benserazide

Movement Disorder Case report

Levodopa/carbidopa

Achilles Tendon Rupture Case report

Levofloxacin

Thyrotoxicosis Case report

Levothyroxine sodium

Breast Augmentation Case report

Lidocaine

Peridural Anesthesia Case report

Lidocaine/epinephrine/ropivacaine

Losartan Case report

Lisinopril

Atenolol Case report

Lisinopril

Haloperidol Case report

Lithium

Acid-Base Imbalance Case report

Lithium

Back Pain Case report

Loperamide withdrawal

Diplopia Case report

Megestrol withdrawal

Choroidal Melanoma Case report

Melphalan

Dapagliflozin Case report

Metformin

Metformin Case report

Metformin overdose

Buprenorphine Case report

Methadone

Bronchoscopy Case report

Methenamine hippurate

Methotrexate Case report

Methotrexate

Nausea Case report

Methotrexate

Human Alphaherpesvirus 3 Case report

Methotrexate/prednisolone/tocilizumab

Attention Deficit Hyperactivity Disorder Case report

Methylphenidate

Naproxen Case report

Methylphenidate/amphetamines/NSAIDs

Giant Cell Arteritis Case report

Methylprednisolone

Tuberculosis Case report

Methylprednisolone

Ciclosporine Case report

Methylprednisolone/prednisolone

Coma Case report

Mirtazapine/sennosides overdose

Acute Adrenal Insufficiency Case report

Mitotane

Allergic Rhinitis Case report

Morphine

Tuberculosis Case report

Moxifloxacin

Conjunctivitis Case report

Moxifloxacin

Melanoma Case report

Multiple drugs

Famotidine Case report

Multiple drugs

Ranibizumab Case report

Multiple drugs

Wound Debridement Case report

Multiple drugs

Cyanosis Case report

Multiple drugs

Glucocorticoid Case report

Multiple drugs

Teicoplanin Case report

Multiple drugs

Hydroxychloroquine Case report

Multiple drugs

Paracetamol Case report

Multiple drugs

Ketoconazole Case report

Multiple drugs interaction

Tacrolimus Case report

Mycophenolate-mofetil/prednisone/tacrolimus

Isosorbide Dinitrate Case report

Mycophenolate/prednisolone/tacrolimus

Metabolic Acidosis Case report

Naproxen overdose

Tyrosine Kinase Inhibitors Case report

Nilotinib

Human Alphaherpesvirus 3 Case report

Nivolumab

Multiple Sclerosis Case report

Ocrelizumab/dimethyl fumarate

Case report

Octreotide

Paracetamol Case report

Olanzapine/risperidone

Nifedipine Case report

Olmesartan-medoxomil

Omalizumab Case report

Omalizumab

Helicobacter Pylori Case report

Omeprazole

Afatinib Case report

Osimertinib

Acute Kidney Injury Case report

Oxaliplatin

Paracetamol Case report

Paracetamol

Hepatic Encephalopathy Case report

Paracetamol overdose

Paracetamol Case report

Paracetamol overdose

Paracetamol Case report

Paracetamol/diphenhydramine overdose

Paracetamol Case report

Paracetamol/sulodexide overdose

Cough Case report

Pazopanib

Soft Tissue Sarcoma Case report

Pazopanib/sirolimus

Hepatocellular Carcinoma Case report

Pembrolizumab

Ketoacidosis Case report

Pembrolizumab

Hypophysitis Case report

Pembrolizumab

Case report

Pembrolizumab

Pneumonia Case report

Pembrolizumab

Lymphoma Case report

Pembrolizumab

Metronidazole Case report

Piperacillin/tazobactam

Sarcoidosis Case report

Pirfenidone

Renal Abscess Case report

Pneumococcal vaccine

Polio Virus Case report

Poliovirus vaccine live oral

Hemophilia Case report

Prednisone

Amiloride Case report

Prednisone

Suicide Case report

Prednisone

Pregabalin Case report

Pregabalin

Somnolence Case report

Promethazine overdose

Propranolol Case report

Propranolol

Vascular Dementia Case report

Psychotropic drugs

Trisomy 21 Case report

Raltegravir

Ribavirin Case report

Ribavirin

Ribavirin Case report

Ribavirin

Glaucoma Case report

Ripasudil

Lymphoma Case report

Rituximab

Bronchiectasis Case report

Rituximab

Septicemia Case report

Rituximab

Tooth Extraction Case report

Rituximab

osteosarcoma Case report

Rivoceranib

Nausea Case report

Semaglutide overdose

Amoxicillin Case report

Sevoflurane

Sildenafil Case report

Sildenafil

Foreign Body Aspiration Case report

Sodium polystyrene sulfonate

Case report

Sodium tetradecyl sulfate

Acute Myeloid Leukemia Case report

Sorafenib

Metoprolol Case report

Sorafenib

Metastasis Case report

Spartalizumab

Acute Kidney Injury Case report

Sulfadiazine

Voriconazole Case report

Sulfamethoxazole

Computed Tomography Case report

Sulfasalazine

Kidney Cancer Case report

Sunitinib

Rapid Sequence Induction Case report

Suxamethonium-chloride

Atopic Dermatitis Case report

Tacrolimus

Vitiligo Case report

Tacrolimus

Tacrolimus Case report

Tacrolimus

Atopic Dermatitis Case report

Tacrolimus

Tricuspid Valve Replacement Case report

Tacrolimus

Melanoma Case report

Talimogene laherparepvec

Nausea Case report

Tenofovir disoproxil fumarate

Hypoparathyroidism Case report

Teriparatide withdrawal

Constipation Case report

Thalidomide

Amisulpride Case report

Thioridazine withdrawal

Clonidine Case report

Tianeptine

Disseminated Intravascular Coagulation Case report

Tocilizumab

Nausea Case report

Topiramate

Topiramate Case report

Topiramate overdose

Breast Cancer Case report

Trastuzumab

Diabetic Retinopathy Case report

Tretinoin

Cataract Case report

Triamcinolone

Sarcoidosis Case report

Triamcinolone

Schizophrenia Case report

Valproic acid

Levofloxacin Case report

Vancomycin

Angioedema Case report

Varenicline

Alopecia Case report

Vemurafenib

Nevi Case report

Vemurafenib

Conisation Case report

Viscum album

Vomiting Case report

Vitamin D

Mitral Valve Replacement Case report

Warfarin

Rabies Case report

Yellow-fever-vaccine

Multiple Myeloma Case report

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Reactions Weekly

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