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3403 search results for:

Vitiligo 

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  1. 01-07-2024 | Vitiligo | Report

    Use of complementary and alternative medicine in vitiligo: a cross-sectional survey

    Vitiligo is characterized by skin depigmentation, which can lead to profound psychological effects and decreased quality of life, especially for those with skin of color. Individuals with vitiligo may utilize complementary and alternative medicine …

  2. 01-07-2024 | Vitiligo | OriginalPaper

    Transcriptional variations at perilesional site in vitiligo patients: probably a fight for cell-survival

    Exploration of gene expression variations is a potential source to unravel biological pathways involved in pathological changes in body and understand the mechanism underneath. Vitiligo patients were explored for gene expression changes …

  3. 16-04-2024 | Ruxolitinib | Online First

    Ruxolitinib Cream 1.5%: A Review in Non-Segmental Vitiligo

    Topical ruxolitinib 1.5% cream (Opzelura®), a Janus kinase (JAK) inhibitor, is the first treatment to be approved in several countries for use in patients aged ≥ 12 years with non-segmental vitiligo. In the identical phase III TRuE-V1 and TRuE-V2 …

  4. Open Access 01-12-2024 | Vitiligo | OriginalPaper

    Protocol for a systematic review and meta-analysis on Janus kinase inhibitors in the management of vitiligo

    Vitiligo is a chronic auto-immune skin disorder caused by the destruction of melanocytes resulting in white patches on the skin and hair in all races where its worldwide prevalence in adults varies from 0.5 to 2% ADDIN EN.CITE [ 1 , 2 ].

  5. 01-07-2024 | Vitiligo | OriginalPaper

    Association between miR-202, miR-211, and miR-1238 gene polymorphisms and risk of vitiligo

    Vitiligo, as a common pigment defect in the skin, hair, and mucous membranes, results from the destruction of melanocytes. Recent investigations have shown that miRNA dysregulation contributes in the pathogenesis of vitiligo. Therefore, in this …

  6. Open Access 30-12-2023 | Vitiligo | OriginalPaper

    Multiple gene-drug prediction tool reveals Rosiglitazone based treatment pathway for non-segmental vitiligo

    Vitiligo is a skin disease characterized by selective loss of melanocytes, which seriously affects the appearance and causes great psychological stress to patients. In this study, we performed a comprehensive analysis of two vitiligo microarray …

  7. 01-04-2024 | Vitiligo | Letter

    Vitiligo is associated with new-onset osteoporosis: a retrospective cohort study

  8. 26-10-2023 | Vitiligo | OriginalPaper

    EGR1 Mediated Reduction of Fibroblast Secreted-TGF-β1 Exacerbated CD8+ T Cell Inflammation and Migration in Vitiligo

    Vitiligo is a T cell-mediated depigment skin disease caused by the complex interplay between melanocyte dysfunction, environmental stimulation, and dysregulated immune signals. Transforming growth factor-β1 (TGF-β1), which typically derives from …

  9. 14-03-2024 | Vitiligo | Online First

    Exploring Therapeutic Approaches for Vitiligo: An Inclusive Review from Translational Modalities to Alternative Therapies

    Vitiligo, or leukoderma, is a complex depigmentation disorder of multifactorial origin. It is associated with significant social concerns, as individuals affected by Vitiligo often experience anxiety, depression, and low self-esteem. Historical …

  10. 01-12-2024 | Vitiligo | ReviewPaper

    308 nm excimer laser and tacrolimus ointment in the treatment of facial vitiligo: a systematic review and meta-analysis

    This study aimed to investigate the effects and safety of 308 nm excimer laser (308 nm EL) and tacrolimus ointment (TO) in the treatment of facial vitiligo (FV). We searched Cochrane Library, PUBMED, EMBASE, CNKI, and WANGFANG from inception to …

  11. 15-01-2024 | Vitiligo | BriefCommunication

    Multi-center retrospective review of vitiligo-like lesions in breast cancer patients treated with cyclin-dependent kinase 4 and 6 inhibitors

    Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) are a newer class of antineoplastic drugs used in conjunction with hormone therapy to treat metastatic breast cancer with hormone receptor-positive and human epidermal growth factor …

  12. Open Access 01-12-2024 | Vitiligo | OriginalPaper

    Being female with vitiligo disease in traditional societies within North Africa

    This study aims to assess the influence of vitiligo illness on the quality of life of female individuals residing in Ajdabiya, Libya. Through this investigation, we aim to enhance our comprehension of the potential impact of cultural norms and …

  13. 24-11-2023 | Vitiligo | ReviewPaper

    Manage vitiligo with a personalised approach: consider old and new treatments

    Vitiligo is an autoimmune condition that causes loss of skin colour. For many years it has been managed using treatments that simply dampen immune and inflammatory responses, including topical corticosteroids and calcineurin inhibitors, oral …

  14. 01-01-2024 | Vitiligo | Letter

    Psychological comorbidities of vitiligo: a retrospective cross-sectional analysis in an urban population

  15. 01-01-2024 | Vitiligo | ReviewPaper

    Practical guidelines for the treatment of vitiligo with the melanocyte-keratinocyte transplantation procedure

    Vitiligo manifests as depigmented macules and patches on the skin and can significantly impact a patient’s quality of life. Despite the availability of several treatment modalities, rates of repigmentation can vary widely among individuals and …

  16. 09-09-2023 | Vitiligo | OriginalPaper

    Regenerative therapy for refractory vitiligo using cultured epithelial sheet grafting

    Autologous cultured epithelial grafting, which reduces surgical invasion of normal skin, is excellent for the treatment of large-area skin defects. The use of cultured epithelium for large-area burns is a typical example [ 1 ]. On the other hand …

  17. Open Access 07-09-2023 | Vitiligo | Letter

    Clinical validation and study of stem cell transplantation in treatment of vitiligo

  18. Open Access 07-08-2023 | Vitiligo | OriginalPaper

    Real-World Treatment Patterns in Patients with Vitiligo in the United States

    Vitiligo is an autoimmune skin disorder characterized by loss of melanocytes resulting in patches of depigmentation, with onset often occurring during childhood or adolescence [ 1 , 2 ]. Triggers of melanocyte death are multifactorial, including …

  19. Open Access 22-09-2023 | Vitiligo | ReviewPaper

    Oxidative Stress and Potential Antioxidant Therapies in Vitiligo: A Narrative Review

    Vitiligo is a chronic skin disorder characterised by the loss of melanocytes and subsequent skin depigmentation. Although many theories have been proposed in the literature, none alone explains the pathogenesis of vitiligo. Oxidative stress has …

  20. Open Access 01-12-2023 | Vitiligo | OriginalPaper

    Estimating health related quality of life effects in vitiligo. Mapping EQ-5D-5 L utilities from vitiligo specific scales: VNS, VitiQoL and re-pigmentation measures using data from the HI-Light trial

    Vitiligo affects 2% of the world’s population with significant impact on health related quality of life (HRQoL) [ 1 ]. Responses from the EQ-5D (EQ-5D-5 L or EQ-5D-3 L) are converted to ‘health utilities’, required by various health technology …

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