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12193 search results for:

Hepatic Encephalopathy 

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  1. 23-04-2024 | Hepatic Encephalopathy | Online First

    A Prospective Multimodal Education Intervention for Providers Does Not Increase Hepatic Encephalopathy Treatment Rates

    Hepatic encephalopathy (HE) is a devastating complication of cirrhosis, presenting clinically as disturbances of consciousness, behavioral disorders, and coma [ 1 ]. Clinically apparent, or overt HE will occur in 40% of patients with cirrhosis [ 1 …

  2. 16-03-2024 | Hepatic Encephalopathy | Online First

    Prophylaxis of hepatic encephalopathy: current and future drug targets

    Hepatic encephalopathy is described by a broad spectrum of neurological and psychiatric aberrations resulting due to advanced liver dysfunction. It is a neurological disorder due to hepatic insufficiency and/or portosystemic shunts. Its clinical …

  3. 08-01-2024 | Hepatic Encephalopathy | ReviewPaper

    Current Management of Hepatic Encephalopathy

    Hepatic encephalopathy (HE) is defined as cerebral dysfunction primarily caused by liver insufficiency or portosystemic shunting that leads to a wide range of neuropsychiatric manifestations ranging from subclinical symptoms to coma [ 1 ]. With HE …

  4. Open Access 01-12-2024 | Rifaximin | OriginalPaper

    Preventive and therapeutic effects of rifaximin on hepatic encephalopathy with differential application dosages and strategies: a network meta-analysis

    Hepatic encephalopathy (HE) is a neuropsychiatric syndrome associated with liver disease, leading to impaired cognitive function, motor activity, and potentially resulting in consciousness and coma [ 1 ]. Elevated blood ammonia and inflammation are …

  5. 13-03-2024 | Septicemia | Online First

    Prognostic role of urinary ketone body in patients with sepsis-associated encephalopathy without hepatic failure: a retrospective cohort study

    Sepsis-associated encephalopathy (SAE) is defined as a dysfunction of the central nervous system experienced during sepsis with variable clinical features. The study aims to identify the prognostic role of urinary ketone bodies in relation to …

  6. 26-03-2024 | Hepatic Encephalopathy | Online First

    Therapeutic Effect of Levetiracetam Against Thioacetamide-Induced Hepatic Encephalopathy Through Inhibition of Oxidative Stress and Downregulation of NF-κB, NLRP3, iNOS/NO, Pro-Inflammatory Cytokines and Apoptosis

    Hepatic encephalopathy (HE) is a serious brain disorder which associated with neurological and psychiatric manifestations. Oxidative stress and neuroinflammation and apoptosis play main roles in the development of brain damage in HE. Levetiracetam …

  7. 13-11-2023 | Hepatic Encephalopathy | OriginalPaper

    Prediction of mortality and overt hepatic encephalopathy undergoing transjugular intrahepatic portosystemic shunt: a retrospective cohort study

    Portal hypertension is a frequent vascular consequence of cirrhosis, leading to some severe complications, such as variceal bleeding and refractory ascites [ 1 ]. Transjugular intrahepatic portosystemic shunt (TIPS), which reduces portal pressure …

  8. Open Access 13-06-2023 | Hepatic Encephalopathy | ReviewPaper

    Hepatic Encephalopathy in Children

    Hepatic encephalopathy, characterized by mental status changes and neuropsychiatric impairment, is associated with chronic liver disease as well as acute liver failure. In children, its clinical manifestations can be challenging to pinpoint.

  9. 12-12-2023 | Hepatic Encephalopathy | EditorialNotes

    Invited Commentary: Pre-existing Hepatic Encephalopathy: Really a Contraindication to Elective TIPS? by Torkian etal

  10. 05-10-2023 | Hepatic Encephalopathy | OriginalPaper

    Pre-existing Hepatic Encephalopathy: Really a Contraindication to Elective TIPS?

    Transjugular Intrahepatic Portosystemic Shunt (TIPS) placement is a common procedure performed by interventional radiologists to treat medically refractory symptoms of portal hypertension [ 1 ]. TIPS has been shown to improve overall survival and …

  11. 19-11-2023 | Hepatic Encephalopathy | ReviewPaper

    Association between sarcopenia and hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in patients with cirrhosis: a systematic review and meta-analysis

    Portal hypertension is the primary consequence of liver cirrhosis, resulting in significant complications, such as variceal bleeding and ascites. The transjugular intrahepatic portosystemic shunt (TIPS) is a well-established therapeutic approach …

  12. 17-11-2023 | Hepatic Encephalopathy | OriginalPaper

    Machine Learning Insights: Predicting Hepatic Encephalopathy After TIPS Placement

    Transjugular intrahepatic portosystemic shunt (TIPS) has been shown to be an effective treatment for two common complications of portal hypertension, variceal bleeding and refractory ascites [ 1 – 3 ]. However, an important complication of the TIPS …

  13. Open Access 01-12-2023 | Hepatic Encephalopathy | OriginalPaper

    Experimental hepatic encephalopathy causes early but sustained glial transcriptional changes

    Hepatic encephalopathy (HE) is a common complication of liver cirrhosis, associated with high morbidity and mortality, for which no brain-targeted therapies exist at present. The interplay between hyperammonemia and inflammation is thought to …

  14. 12-12-2023 | Sarcopenia | Online First

    Sarcopenia is a risk factor for post-transjugular intrahepatic portosystemic shunt hepatic encephalopathy and mortality: A systematic review and meta-analysis

    Transjugular intrahepatic portosystemic shunt (TIPS) is a procedure performed to address complications of portal hypertension such as variceal bleeding or ascites refractory to medical therapy [ 1 ]. However, TIPS results in the redirection of …

  15. 17-08-2023 | Hepatic Encephalopathy | OriginalPaper

    Prevalence of hepatic encephalopathy in patients with non-cirrhotic portal hypertension: A systematic review and meta-analysis

    Hepatic encephalopathy (HE) is a common complication occurring in 30% to 40% of cirrhotic patients, which is associated with reduced survival and impaired quality of life (QOL) and marks the transition in the natural history of cirrhosis [ 1 ].

  16. 24-07-2023 | Hepatic Encephalopathy | OriginalPaper

    White matter microstructural disruption in minimal hepatic encephalopathy: a neurite orientation dispersion and density imaging (NODDI) study

    Minimal hepatic encephalopathy (MHE), as the mildest stage of HE, refers to cirrhotic patients without clinical symptoms but who display abnormal neurocognitive functions, brain metabolism, and electrophysiological parameters [ 1 ]. Several studies …

  17. Open Access 02-08-2023 | Hepatic Encephalopathy | OriginalPaper

    3D automatic liver and spleen assessment in predicting overt hepatic encephalopathy before TIPS: a multi-center study

    Portal hypertension due to cirrhosis can lead to variceal bleeding and refractory ascites [ 1 ]. Transjugular intrahepatic portosystemic shunt (TIPS), which establishes a channel between the portal and hepatic veins, is one of the alternative …

  18. Open Access 09-02-2023 | Cerebral Sinus Venous Thrombosis | OriginalPaper

    Pathogenesis of acute encephalopathy in acute hepatic porphyria

    Acute encephalopathy (AE) can be a manifestation of an acute porphyric attack. Clinical data were studied in 32 patients during AE with or without polyneuropathy (PNP) together with 12 subjects with PNP but no AE, and 17 with dysautonomia solely.

  19. Open Access 01-12-2023 | Hepatic Encephalopathy | OriginalPaper

    Establishment and validation of a prognosis nomogram for MIMIC-III patients with liver cirrhosis complicated with hepatic encephalopathy

    Hepatic encephalopathy (HE) is a severe brain dysfunction secondary to liver insufficiency or portal shunt, in which clinical symptoms vary greatly from slight mental disorder to coma [ 1 ]. Most patients with liver cirrhosis have different …

  20. 29-11-2022 | Hepatic Encephalopathy | ReviewPaper

    Prevention of post-tips hepatic encephalopathy: The search of the ideal candidate

    Transjugular intrahepatic portosystemic shunt (TIPS) has been used since more than 25 years to treat some of the complications of portal hypertension, especially variceal bleeding and ascites refractory to conventional therapy. TIPS establishes a …

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