Issue 1/2024
Content (170 Articles)
RNA m6A methylation regulators in liver cancer
Qiaoping Xu, Ning Ren, Lanqi Ren, Yibei Yang, Junjie Pan, Hongkai Shang
Development and validation of a disulfidptosis and disulfide metabolism-related risk index for predicting prognosis in lung adenocarcinoma
Leqi Zhong, Wuguang Chang, Bin Luo, Wuyou Gao, Huanhuan He, Mouxiang Fang, Hongmu Li, Zhesheng Wen, Youfang Chen
TEP SNORD12B, SNORA63, and SNORD14E as novel biomarkers for hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC)
Xuan Zhao, Guanxuan Chen, Yawen Wu, Xiao Li, Zhe Zhang, Li Xie, Xianrang Song, Xingguo Song
LncRNA FOXD1-AS1 regulates pancreatic cancer stem cell properties and 5-FU resistance by regulating the miR-570-3p/SPP1 axis as a ceRNA
Liu Ouyang, Min-min Sun, Ping-sheng Zhou, Yi-wei Ren, Xin-yu Liu, Wan-ying Wei, Zhen-shun Song, Kai Lu, Li-xue Yang
PDGF-BB accelerates TSCC via fibroblast lactates limiting miR-26a-5p and boosting mitophagy
Jianguo Xu, Li Bian, Dingyun You, Ziliang Li, Tingting Wang, Yiting Li, Xiaobin Ren, Yongwen He
Abnormal arginine synthesis confers worse prognosis in patients with middle third gastric cancer
Lianlian Hong, Xi Tang, Jing Han, Jiaqi Wang, Qianqian Xu, Xin Zhu
KCNA1 promotes the growth and invasion of glioblastoma cells through ferroptosis inhibition via upregulating SLC7A11
Weichao Wang, Yang Zhang, Xuetao Li, Qinzi E, Zuoyu Jiang, Qikun Shi, Yu Huang, Jian Wang, Yulun Huang
ATP1A1 is a promising new target for melanoma treatment and can be inhibited by its physiological ligand bufalin to restore targeted therapy efficacy
Laura Soumoy, Aline Genbauffe, Lena Mouchart, Alexandra Sperone, Anne Trelcat, Léa Mukeba-Harchies, Mathilde Wells, Bertrand Blankert, Ahmad Najem, Ghanem Ghanem, Sven Saussez, Fabrice Journe
Transcription factors-related molecular subtypes and risk prognostic model: exploring the immunogenicity landscape and potential drug targets in hepatocellular carcinoma
Meixia Wang, Hanyao Guo, Bo Zhang, Yanan Shang, Sidi Zhang, Xiaoyu Liu, Pengxiu Cao, Yumei Fan, Ke Tan
Immune checkpoint inhibitors in gastrointestinal malignancies: an Umbrella review
Maryam Noori, Farideh Jafari-Raddani, Zeinab Davoodi-Moghaddam, Mahda Delshad, Saeid Safiri, Davood Bashash
Altering phosphorylation in cancer through PP2A modifiers
Hannah Johnson, Satya Narayan, Arun K. Sharma
RORα inhibits gastric cancer proliferation through attenuating G6PD and PFKFB3 induced glycolytic activity
Xiaoshan Wang, Junyi Zhang, Yuwei Wu, Yuqing Zhang, Siyuan Zhang, Angqing Li, Jian Wang, Zhengguang Wang
Clinical applications and perspectives of circulating tumor DNA in gastric cancer
Jing-Han Li, Dan-Ying Zhang, Ji-Min Zhu, Ling Dong
Identification of TNFRSF21 as an inhibitory factor of osteosarcoma based on a necroptosis-related prognostic gene signature and molecular experiments
Xiang Li, Zhenqian Sun, Jinlong Ma, Miaomiao Yang, Hongxin Cao, Guangjun Jiao
Role of long non-coding RNAs in metabolic reprogramming of gastrointestinal cancer cells
Kang Wang, Yan Lu, Haibin Li, Jun Zhang, Yongle Ju, Manzhao Ouyang
Interplay of miRNAs and lncRNAs in STAT3 signaling pathway in colorectal cancer progression
Omid Rahbar Farzam, Souzan Najafi, Mohammad Amini, Zohreh Rahimi, Reza Dabbaghipour, Omid Zohdi, Ghazale Asemani Shahgoli, Behzad Baradaran, Bahman Akbari
Mechanism study of oleanolic acid derivative, K73-03, inducing cell apoptosis in hepatocellular carcinoma
Jiaqi Wang, Chuchu Ma, Zhongyuan Tang, Zhengwu Sun, Eskandar Qaed, Xinming Chi, Jun Wang, Yazeed Jamalat, Zhaohong Geng, Zeyao Tang, Qiying Yao
A serum panel of three microRNAs may serve as possible biomarkers for kidney renal clear cell carcinoma
Zhenyu Wen, Yingqi Li, Zhengping Zhao, Rongkang Li, Xinji Li, Chong Lu, Chen Sun, Wenkang Chen, Zhenjian Ge, Liangchao Ni, Yongqing Lai
Disulfidptosis-related signature predicts prognosis and characterizes the immune microenvironment in hepatocellular carcinoma
Jun Tang, Xintong Peng, Desheng Xiao, Shuang Liu, Yongguang Tao, Long Shu
Upregulation of TTK expression is associated with poor prognosis and immune infiltration in endometrial cancer patients
Hongxiang Du, Li Zhang, Jia Chen, Xinyi Chen, Ronghui Qiang, Xiaoyi Ding, Yilang Wang, Xiaoqing Yang
Immunomodulation of cuproptosis and ferroptosis in liver cancer
Jia-qian Mo, Shen-yan Zhang, Qiang Li, Mo-xian Chen, Yue-qing Zheng, Xin Xie, Rongxin Zhang, Shan-shan Wang
Identification of a new gene signature for prognostic evaluation in cervical cancer: based on cuproptosis-associated angiogenesis and multi-omics analysis
Jiawen Kang, Jingwen Jiang, Xiaoqing Xiang, Yong Zhang, Jie Tang, Lesai Li
Possible prognostic impact of PKCι genetic variants in prostate cancer
Amna Hafeez, Maria Shabbir, Khushbukhat Khan, Janeen H. Trembley, Yasmin Badshah, Sameen Zafar, Kanza Shahid, Hania Shah, Naeem Mahmood Ashraf, Arslan Hamid, Tayyaba Afsar, Ali Almajwal, Afifa Marium, Suhail Razak
DNA mismatch repair system regulates the expression of PD-L1 through DNMTs in cervical cancer
Fan Guo, Ruijiao Lu, Weina Kong, Miyessar Anwar, Yangchun Feng
Non-coding RNAs as potential therapeutic targets for receptor tyrosine kinase signaling in solid tumors: current status and future directions
Aysan Moeinafshar, Mohammad Nouri, Nima Shokrollahi, Mahdi Masrour, Amirmohammad Behnam, Sahand Tehrani Fateh, Hossein Sadeghi, Mohammad Miryounesi, Mohammad-Reza Ghasemi
Targeting cholesterol impairs cell invasion of all breast cancer types
Mauriane Maja, Marie Verfaillie, Patrick Van Der Smissen, Patrick Henriet, Christophe E. Pierreux, Nor Eddine Sounni, Donatienne Tyteca
Navigating challenges: optimising methods for primary cell culture isolation
Oliwia Piwocka, Marika Musielak, Karolina Ampuła, Igor Piotrowski, Beata Adamczyk, Magdalena Fundowicz, Wiktoria Maria Suchorska, Julian Malicki
Platinum-based drugs induce phenotypic alterations in nucleoli and Cajal bodies in prostate cancer cells
Enkhzaya Batnasan, Minttu Kärkkäinen, Sonja Koivukoski, Nithin Sadeesh, Sylvain Tollis, Pekka Ruusuvuori, Mauro Scaravilli, Leena Latonen
Integrating bioinformatics and experimental validation to unveil disulfidptosis-related lncRNAs as prognostic biomarker and therapeutic target in hepatocellular carcinoma
Lixia Xu, Shu Chen, Qiaoqiao Li, Xinyi Chen, Yuan Xu, Yongjian Zhou, Juan Li, Zhixian Guo, Jiyuan Xing, Di Chen
What role does GPR65 play in the progression of osteosarcoma? Its mechanism and clinical significance
Jin Qi, Sihang Liu, Zhirui Zhang
USP5 facilitates bladder cancer progression by stabilizing the c-Jun protein
Hui-hui Zhang, An-qi Zhang, Peng Peng, Liang Huang, Cai-ying Liu, Xin-rui Nie, De-fu Hou, Xia Zhang, Shang-ze Li
USP29 activation mediated by FUBP1 promotes AURKB stability and oncogenic functions in gastric cancer
Rongfu Tu, Ye Kang, Yiwen Pan, Yanyan Da, Doudou Ren, Ru Zhang, Zeqiong Cai, Yijia Liu, Jiao Xu, Junpeng Ma, Zhiyong Zhou, Shupeng Yin, Xiaozhuang Li, Peng Zhang, Qi Zhang, Jingchao Wang, Xinlan Lu, Chengsheng Zhang
TIPARP as a prognostic biomarker and potential immunotherapeutic target in male papillary thyroid carcinoma
Jianlin Zhang, Xumin Zhou, Fan Yao, JiaLi Zhang, Qiang Li
Microglia-mediated drug substance transfer promotes chemoresistance in brain tumors: insights from an in vitro co-culture model using GCV/Tk prodrug system
Sheng-Yan Wu, Wen-Jui Yu, Ting-Yi Chien, Yu-An Ren, Chi-Shuo Chen, Chi-Shiun Chiang
Establishment of tumor microenvironment-preserving organoid model from patients with intracranial meningioma
Dokyeong Kim, Junseong Park, Hyeon-Chun Park, Songzi Zhang, Minyoung Park, Soon A. Park, Sug Hyung Lee, Youn Soo Lee, Jae-Sung Park, Sin-Soo Jeun, Yeun-Jun Chung, Stephen Ahn
The roles and molecular mechanisms of non-coding RNA in cancer metabolic reprogramming
Shizhen Li, Mingjing Peng, Shiming Tan, Linda Oyang, Jinguan Lin, Longzheng Xia, Jiewen Wang, Nayiyuan Wu, Xianjie Jiang, Qiu Peng, Yujuan Zhou, Qianjin Liao
Stress granules affect the dual PI3K/mTOR inhibitor response by regulating the mitochondrial unfolded protein response
Nan Lin, Liankun Sun, Jiannan Chai, Hang Qi, Yuanxin Zhao, Jiaoyan Ma, Meihui Xia, Xiaoqing Hu
Retraction Note: Exosomal lncRNA HNF1A-AS1 affects cisplatin resistance in cervical cancer cells through regulating microRNA-34b/TUFT1 axis
Xiaoqiong Luo, Jingxi Wei, Feng-lian Yang, Xiao-xia Pang, Feng Shi, Yu-xia Wei, Bi-yun Liao, Jun-li Wang
Correction: circular RNAs in renal cell carcinoma: from mechanistic to clinical perspective
Chunjie Huang, Pooya Esfandi Sarafraz, Parisa Enayati, Elham Mortazavi Mamaghani, Emad Babakhanzadeh, Majid Nazari
B cells in head and neck squamous cell carcinoma: current opinion and novel therapy
Xinyue Guo, Licheng Xu, Luan Nie, Chenyu Zhang, Yaohui Liu, Rui Zhao, Jing Cao, Linli Tian, Ming Liu
CircRAD23B promotes proliferation and carboplatin resistance in ovarian cancer cell lines and organoids
Hui Wang, Yashuang Zhang, Huixian Miao, Ting Xu, Xianglin Nie, Wenjun Cheng
The anti-tumor effects of AZD4547 on ovarian cancer cells: differential responses based on c-Met and FGF19/FGFR4 expression
Yoo-Young Lee, Ji-Yoon Ryu, Young-Jae Cho, Ju-Yeon Choi, Jung-Joo Choi, Chel Hun Choi, Jason K. Sa, Jae Ryoung Hwang, Jeong-Won Lee
Single-cell N6-methyladenosine-related genes function within the tumor microenvironment to affect the prognosis and treatment sensitivity in patients with gastric cancer
Zehua Wang, Chen Chen, Jiao Shu, Jiaoyu Ai, Yihan Liu, Haoyue Cao, Yongxu Jia, Yanru Qin
Elucidating the role of Pyroptosis in papillary thyroid cancer: prognostic, immunological, and therapeutic perspectives
Fang Li, Rui Du, Jiedong Kou, Jingting Li, Le Zhou, Daqi Zhang, Yantao Fu, Gianlorenzo Dionigi, Simona Bertoli, Hui Sun, Nan Liang
Fabrication of magnetic niosomal platform for delivery of resveratrol: potential anticancer activity against human pancreatic cancer Capan-1 cell
Akram Firouzi Amandi, Zahra Bahmanyar, Mehdi Dadashpour, Mehrnoosh Lak, Mohammad Natami, Yusuf Döğüş, Mahsa Alem, Omid Ali Adeli
The m6A methyltransferase METTL3 drives thyroid cancer progression and lymph node metastasis by targeting LINC00894
Xiang Zhou, Lisha Chang, Qiaoqiao Liang, Rongjie Zhao, Yong Xiao, Zheng Xu, Leitao Yu
MicroRNA expression signature as a biomarker in the diagnosis of nodal T-cell lymphomas
Muhammad Sufyan Bin Masroni, Gracie Wee Ling Eng, Ah-Jung Jeon, Yuan Gao, He Cheng, Sai Mun Leong, Jit Kong Cheong, Susan Swee-Shan Hue, Soo Yong Tan
An estrogen-regulated long non-coding RNA NCALD promotes luminal breast cancer proliferation by activating GRHL2
Yue Meng, Dianrong Zhou, Ying Luo, Jierong Chen, Hui Li
PD-1 inhibitor plus oncolytic vaccinia virus is a safe and effective treatment option for metastatic renal cell carcinoma
Jee Soo Park, Myung Eun Lee, Jongchan Kim, Keunhee Oh, Namhee Lee, Minsun Jung, Won Sik Jang, Won Sik Ham
EN1 promotes lung metastasis of salivary adenoid cystic carcinoma by regulating the PI3K-AKT pathway and epithelial-mesenchymal transition
Yajuan Cui, Ye Zhang, Yuping Liu, Zheng Zhou, Lijing Zhu, Chuan-Xiang Zhou
Robust machine−learning based prognostic index using cytotoxic T lymphocyte evasion genes highlights potential therapeutic targets in colorectal cancer
Xu Wang, Shixin Chan, Jiajie Chen, Yuanmin Xu, Longfei Dai, Qijun Han, Zhenglin Wang, Xiaomin Zuo, Yang Yang, Hu Zhao, Ming Wang, Chen Wang, Zichen Li, Huabing Zhang, Wei Chen
Anoikis-related signature predicts prognosis and characterizes immune landscape of ovarian cancer
Jiani Yang, Yue Zhang, Shanshan Cheng, Yanna Xu, Meixuan Wu, Sijia Gu, Shilin Xu, Yongsong Wu, Chao Wang, Yu Wang
ANGPTL4 regulates ovarian cancer progression by activating the ERK1/2 pathway
Jiaqi Xu, Fei Wu, Yue Zhu, Tiantian Wu, Tianyue Cao, Wenxin Gao, Meng Liu, Weifeng Qian, Guannan Feng, Xiaoxue Xi, Shunyu Hou
Identification of four snoRNAs (SNORD16, SNORA73B, SCARNA4, and SNORD49B) as novel non-invasive biomarkers for diagnosis of breast cancer
Xiao Li, Xuan Zhao, Li Xie, Xingguo Song, Xianrang Song
Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
Valeria Pecci, Fabiola Troisi, Aurora Aiello, Sara De Martino, Angela Carlino, Vincenzo Fiorentino, Cristian Ripoli, Dante Rotili, Francesco Pierconti, Maurizio Martini, Manuela Porru, Francesco Pinto, Antonello Mai, Pier Francesco Bassi, Claudio Grassi, Carlo Gaetano, Alfredo Pontecorvi, Lidia Strigari, Antonella Farsetti, Simona Nanni
Spatial and single-cell analyses uncover links between ALKBH1 and tumor-associated macrophages in gastric cancer
Renin Chang, Kuan-Hao Tsui, Li-Fei Pan, Chia-Jung Li
Integrated bioinformatics analysis of SEMA3C in tongue squamous cell carcinoma using machine-learning strategies
Huixin Dou, Can Song, Xiaoyan Wang, Zhien Feng, Yingying Su, Hao Wang
Peroxiredoxin 3 regulates breast cancer progression via ERK-mediated MMP-1 expression
Pei-Jou Chua, Suet-Hui Ow, Cheng-Teng Ng, Wan-Hong Huang, Jie-Ting Low, Puay Hoon Tan, Michael W.Y. Chan, Boon-Huat Bay
IGFBP3 induces PD-L1 expression to promote glioblastoma immune evasion
Leilei Zhao, Yudi Wang, Peizheng Mu, Xuehua Zhang, Ruomei Qi, Yurui Zhang, He Zhang, Xiao Zhu, Zhouyan Dong, Yucui Dong
METTL14 enhances the m6A modification level of lncRNA MSTRG.292666.16 to promote the progression of non-small cell lung cancer
Xianxiu Ji, Xiaoying Wan, Hui Sun, Qinfang Deng, Shuyan Meng, Boxiong Xie, Songwen Zhou
Insulin receptor alternative splicing in breast and prostate cancer
Jinyu Li, Gena Huang
Melanoma biology and treatment: a review of novel regulated cell death-based approaches
Ming-yun Hsieh, Sheng-Kai Hsu, Tzu-Yu Liu, Chang-Yi Wu, Chien-Chih Chiu
NY-ESO-1-specific T cell receptor-engineered T cells and Tranilast, a TRPV2 antagonist bivalent treatment enhances the killing of esophageal cancer: a dual-targeted cancer therapeutic route
Obed Boadi Amissah, Wenfang Chen, Jean de Dieu Habimana, Yirong Sun, Lihui Lin, Yujie Liu, Ling Wang, Zhaoming Liu, Omar Mukama, Rajesh Basnet, Hohua Liu, Junyi Li, Xuanyan Ding, Lingshuang Lv, Min Chen, Yalin Liang, Rongqi Huang, Zhiyuan Li
Novel lncRNAs LINC01221, RP11-472G21.2 and CRNDE are markers of differential expression in pediatric patients with T cell acute lymphoblastic leukemia
Pankaj Sharma, Parminder kaur, Prateek Bhatia, Amita Trehan, Sreejesh Sreedharanunni, Minu Singh
PHF6 loss reduces leukemia stem cell activity in an acute myeloid leukemia mouse model
Shengnan Yuan, Mingming Gao, Yizhou Wang, Yanjie Lan, Mengrou Li, Yuwei Du, Yue Li, Wen Ju, Yujin Huang, Ke Yuan, Lingyu Zeng
Targeted drug delivery using nanobodies to deliver effective molecules to breast cancer cells: the most attractive application of nanobodies
Mohadeseh Haji Abdolvahab, Pegah Karimi, Nasrin Mohajeri, Mohammad Abedini, Hamed Zare
A cuproptosis score model and prognostic score model can evaluate clinical characteristics and immune microenvironment in NSCLC
Yijie Tang, Tianyi Wang, Qixuan Li, Jiahai Shi
AAA237, an SKP2 inhibitor, suppresses glioblastoma by inducing BNIP3-dependent autophagy through the mTOR pathway
Yizhi Zhang, Wan Li, Yihui Yang, Sen Zhang, Hong Yang, Yue Hao, Xu Fang, Guanhua Du, Jianyou Shi, Lianqiu Wu, Jinhua Wang
Retraction Note: Down-regulation of LINC00472 promotes osteosarcoma tumorigenesis by reducing FOXO1 expressions via miR-300
Jingwei Zhang, Jieyuan Zhang, Dong Zhang, Weifeng Ni, Haijun Xiao, Bizeng Zhao
YY1: a key regulator inhibits gastric cancer ferroptosis and mediating apatinib-resistance
Zi-Han Geng, Jun-Xian Du, Yue-Da Chen, Pei-Yao Fu, Ping-Hong Zhou, Wen-Zheng Qin, Yi-Hong Luo
Extracellular vesicles produced by irradiated endothelial or Glioblastoma stem cells promote tumor growth and vascularization modulating tumor microenvironment
Giorgia Castellani, Mariachiara Buccarelli, Quintino Giorgio D’Alessandris, Ramona Ilari, Andrea Cappannini, Francesca Pedini, Alessandra Boe, Valentina Lulli, Isabella Parolini, Stefano Giannetti, Mauro Biffoni, Vincenzo Zappavigna, Giovanna Marziali, Roberto Pallini, Lucia Ricci-Vitiani
PLK1 phosphorylates RhoGDI1 and promotes cancer cell migration and invasion
Jeewon Lim, Yo Sep Hwang, Hyang Ran Yoon, Jiyun Yoo, Suk Ran Yoon, Haiyoung Jung, Hee Jun Cho, Hee Gu Lee
Icariin exerts anti-tumor activity by inducing autophagy via AMPK/mTOR/ULK1 pathway in triple-negative breast cancer
Mei Zhao, Panling Xu, Wenjing Shi, Juan Wang, Ting Wang, Ping Li
RhoB expression associated with chemotherapy response and prognosis in colorectal cancer
Maria Kopsida, Na Liu, Angeliki Kotti, Jing Wang, Lasse Jensen, Ganesan Jothimani, Camilla Hildesjo, Staffan Haapaniemi, Wen Zhong, Surajit Pathak, Xiao-Feng Sun
Correction: A novel mechanism by which ACTA2-AS1 promotes cervical cancer progression: acting as a ceRNA of miR-143-3p to regulate SMAD3 expression
Lingli Luo, Min Wang, Xianping Li, Can Luo, Shan Tan, Sheng Yin, Lei Liu, Xiaolin Zhu
The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization
Juan Sun, Jie Li, Kostas Pantopoulos, Yuqin Liu, Yixuan He, Weiming Kang, Xin Ye
Signature construction and molecular subtype identification based on liver-specific genes for prediction of prognosis, immune activity, and anti-cancer drug sensitivity in hepatocellular carcinoma
Xiuzhi Zhang, Zhefeng Xiao, Xia Zhang, Ningning Li, Tao Sun, JinZhong Zhang, Chunyan Kang, Shasha Fan, Liping Dai, Xiaoli liu
Platycodin D2 enhances P21/CyclinA2-mediated senescence of HCC cells by regulating NIX-induced mitophagy
Lili Sun, Yaru Li, Renshuang Zhao, Qinlei Fan, Fei Liu, Yilong Zhu, Jicheng Han, Yunyun Liu, Ningyi Jin, Xiao Li, Yiquan Li
RNA-binding proteins signature is a favorable biomarker of prognosis, immunotherapy and chemotherapy response for cervical cancer
Xiaomei Chen, Xunhu Dong, Hong Li, Tingting Wu, Haoyin Liu, Jie Wu, Wei Ge, Lingji Hao, Zhe Zhang
Super enhancer related gene ANP32B promotes the proliferation of acute myeloid leukemia by enhancing MYC through histone acetylation
Xiaomei Wan, Jianwei Wang, Fang Fang, Yixin Hu, Zimu Zhang, Yanfang Tao, Yongping Zhang, Juanjuan Yu, Yumeng Wu, Bi Zhou, Hongli Yin, Li Ma, Xiaolu Li, Ran Zhuo, Wei Cheng, Shuqi Zhang, Jian Pan, Jun Lu, Shaoyan Hu
Retraction Note: GPX8 is transcriptionally regulated by FOXC1 and promotes the growth of gastric cancer cells through activating the Wnt signaling pathway
Hong Chen, Lu Xu, Zhi-li Shan, Shu Chen, Hao Hu
Genome-wide CRISPR screen identifies ESPL1 limits the response of gastric cancer cells to apatinib
Bei Zhang, Yan Chen, Xinqi Chen, Zhiyao Ren, Hong Xiang, Lipeng Mao, Guodong Zhu
Emerging trends in the coexistence of primary lung Cancer and hematologic malignancy: a comprehensive analysis of clinicopathological features and genetic abnormalities
Mengchen Lyu, Lifeng Luo, Ling Zhou, Xiangran Feng, Jin Yang, Ziwei Xu, Xianwen Sun, Zhiyao Bao, Xiaofei Wang, Beili Gao, Yi Xiang
SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway
Haiting Zhou, Jiahao Li, Yi He, Xiaohui Xia, Junxia Liu, Huihua Xiong
ACADL-YAP axis activity in non-small cell lung cancer carcinogenicity
Kegong Chen, Chunqiao Hong, Weibo Kong, Guanghua Li, Zhuang Liu, Kechao Zhu, Chen Lu, Panpan Si, Pan Gao, Guangyao Ning, Renquan Zhang
LASS2 suppresses metastasis in multiple cancers by regulating the ferroptosis signalling pathway through interaction with TFRC
Yunfei Huang, Jie Du, Dan Li, Wei He, Zhouheng Liu, Li Liu, Xiaoli Yang, Xiaoming Cheng, Rui Chen, Yan Yang
The emerging roles of sphingosine 1-phosphate and SphK1 in cancer resistance: a promising therapeutic target
Samar Sami Alkafaas, Mohamed I. Elsalahaty, Doha F. Ismail, Mustafa Ali Radwan, Sara Samy Elkafas, Samah A. Loutfy, Rami M. Elshazli, Narjes Baazaoui, Ahmed Ezzat Ahmed, Wael Hafez, Mohanad Diab, Mohamed Sakran, Mohamed T. El-Saadony, Khaled A. El-Tarabily, Hani K. Kamal, Mohamed Hessien
PPP2R1B abolishes colorectal cancer liver metastasis and sensitizes Oxaliplatin by inhibiting MAPK/ERK signaling pathway
Wei Liu, Jingtong Tang, Wei Gao, Jian Sun, Gang Liu, Jianping Zhou
The circRNA hsa-circ-0013561 regulates head and neck squamous cell carcinoma development via the miR-7-5p/PDK3 axis
Kaisai Tian, Liying Zheng, Tailei Yuan, Xiaoping Chen, Qun Chen, Xiaocheng Xue, Shuixian Huang, Weining He, Mingming Jin, Yi Zhang
A cuproptosis-related gene expression signature predicting clinical prognosis and immune responses in intrahepatic cholangiocarcinoma detected by single-cell RNA sequence analysis
Hefei Ren, Chang Liu, Cheng Zhang, Hongkun Wu, Jiafeng Zhang, Zhenhua Wang, Lei Chen, Huiquan Wang, Chenghao Shao, Lin Zhou
RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway
Xiaoyan Ding, Xiaoxia Li, Yanxia Jiang, Yujun Li, Hong Li, Lipeng Shang, Guilin Feng, Huhu Zhang, Ziyuan Xu, Lina Yang, Bing Li, Robert Chunhua Zhao
Targeting HER2-positive breast cancer cells by a combination of dasatinib and BMS-202: Insight into the molecular pathways
Hadeel Kheraldine, Ishita Gupta, Farhan Sachal Cyprian, Semir Vranic, Halema F. Al-Farsi, Maysaloun Merhi, Said Dermime, Ala-Eddin Al Moustafa
Transmembrane protein 176B regulates amino acid metabolism through the PI3K-Akt-mTOR signaling pathway and promotes gastric cancer progression
Jing Li, ZiQing Fang, Emre Dal, Hao Zhang, KeXun Yu, MengDi Ma, MingLiang Wang, Ruochuan Sun, MingDian Lu, HuiZhen Wang, YongXiang Li
N6-methyladenosine levels in peripheral blood RNA: a potential diagnostic biomarker for colorectal cancer
Chunying Zhang, Jiadi Chen, Jingyi Ren, Xiaoyu Li, Yaqin Zhang, Bihan Huang, Yihan Xu, Luyan Dong, Yingping Cao
Mitochondrial respiratory chain component NDUFA4: a promising therapeutic target for gastrointestinal cancer
Quanling Zhou, Xiaohui Li, Honglian Zhou, Juanjuan Zhao, Hailong Zhao, Lijuan Li, Ya Zhou
Application status and optimization suggestions of tumor organoids and CAR-T cell co-culture models
Rong-Xuan Ning, Cun-Yu Liu, Shi-Qi Wang, Wen-Kai Li, Xia Kong, Zhi-Wei He
Impact of NDUFAF6 on breast cancer prognosis: linking mitochondrial regulation to immune response and PD-L1 expression
Baohong Jiang, Sixuan Wu, Lijun Zeng, Yuanbin Tang, Lunqi Luo, Lianjie Ouyang, Wenjie Feng, Yeru Tan, Yuehua Li
Perspective view of allogeneic IgG tumor immunotherapy
Ying Liu, Yuanyi Huang, Hong-Wei Cui, YingYing Wang, ZhaoWu Ma, Ying Xiang, Hong-Yi Xin, Jun-Qing Liang, Hong-Wu Xin
Roles and mechanisms of aberrant alternative splicing in melanoma — implications for targeted therapy and immunotherapy resistance
Wanxian Chen, Deyi Geng, Jiasheng Chen, Xiaosha Han, Qihu Xie, Genghong Guo, Xuefen Chen, Wancong Zhang, Shijie Tang, Xiaoping Zhong
MicroRNAs as regulators of immune checkpoints in cancer immunotherapy: targeting PD-1/PD-L1 and CTLA-4 pathways
Arefeh Zabeti Touchaei, Sogand Vahidi
Influential upregulation of KCNE4: Propelling cancer associated fibroblasts-driven colorectal cancer progression
Zizhen Zhang, Shengde Liu, Zhenghang Wang, Shuo Wang, Lei Jiang, Xicheng Wang, Jian Li, Lin Shen
Decoding contextual crosstalk: revealing distinct interactions between non-coding RNAs and unfolded protein response in breast cancer
Negin Karamali, Arshia Daraei, Arman Rostamlou, Roya Mahdavi, Zahra Akbari Jonoush, Nooshin Ghadiri, Zahra Mahmoudi, Amirhossein Mardi, Moslem Javidan, Sepideh Sohrabi, Behzad Baradaran
Immune modulation in malignant pleural effusion: from microenvironment to therapeutic implications
Shan Ge, Yuwei Zhao, Jun Liang, Zhongning He, Kai Li, Guanghui Zhang, Baojin Hua, Honggang Zheng, Qiujun Guo, Runzhi Qi, Zhan Shi
Uncovering the cellular and omics characteristics of natural killer cells in the bone marrow microenvironment of patients with acute myeloid leukemia
Leisheng Zhang, Yunyan Sun, Chun-e Xue, Shuling Wang, Xianghong Xu, Chengyun Zheng, Cunrong Chen, Dexiao Kong
Neighboring macrophage-induced alteration in the phenotype of colorectal cancer cells in the tumor budding area
Ichiro Kawamura, Rintaro Ohe, Kazushi Suzuki, Takanobu Kabasawa, Takumi Kitaoka, Daiichiro Takahara, Michihisa Kono, Naoya Uchiyama, Hiroaki Musha, Mitsuru Futakuchi, Fuyuhiko Motoi
Aptamers as an approach to targeted cancer therapy
Fatemeh Mahmoudian, Azin Ahmari, Shiva Shabani, Bahman Sadeghi, Shohreh Fahimirad, Fahimeh Fattahi
Soluble Periostin is a potential surveillance biomarker for early and long-term response to chemotherapy in advanced breast cancer
Li Jia, Wenwei Hu, Xu Yan, Jie Shao, Yuhong Guo, Aimin Zhang, Lianzi Yu, Yunli Zhou, Yueguo Li, Li Ren, Dong Dong
Coordinated activation of DNMT3a and TET2 in cancer stem cell-like cells initiates and sustains drug resistance in hepatocellular carcinoma
Tao Cheng, Changli Zhou, Sicheng Bian, Kelsey Sobeck, Yahui Liu
LncRNA WFDC21P interacts with SEC63 to promote gastric cancer malignant behaviors by regulating calcium homeostasis signaling pathway
Jinyao Dong, Yongqiang Lv, Debin Meng, Ruyi Shi, Feng Li, Rui Guo, Yi Wang, Jiansheng Guo, Yanyan Zhang
Integrated analysis of disulfidptosis-related immune genes signature to boost the efficacy of prognostic prediction in gastric cancer
Jie Li, Tian Yu, Juan Sun, Mingwei Ma, Zicheng Zheng, Yixuan He, Weiming Kang, Xin Ye
LncRNA RASAL2-AS1 promotes METTL14-mediated m6A methylation in the proliferation and progression of head and neck squamous cell carcinoma
Meiting Rong, Ming Zhang, Feihong Dong, Ke Wu, Bingkun Cai, Jinrui Niu, Le Yang, Zhongyan Li, Hui-yi Lu
Domperidone inhibits cell proliferation via targeting MEK and CDK4 in esophageal squamous cell carcinoma
Qiang Yuan, Yunshu Shi, Yuhan Zhang, Yaqian Shi, Zubair Hussain, Jimin Zhao, Yanan jiang, Yan Qiao, Yaping Guo, Jing Lu, Ziming Dong, Zigang Dong, Junyong Wang, Kangdong Liu
The upregulation of VGF enhances the progression of oral squamous carcinoma
Chung-Hsien Chou, Chun-Han Yen, Chung-Ji Liu, Hsi-Feng Tu, Shu-Chun Lin, Kuo-Wei Chang
Characterization of the biological and transcriptomic landscapes of bone marrow-derived mesenchymal stem cells in patients with multiple myeloma
Yu Lu, Chaohui Zheng, Wenxia Zhang, Xuan Liu, Ziwei Zhou, Zhenzhen Wang, Huan Hua, Zhengrong Song, Xuejun Zhang, Shuyi Liu, Leisheng Zhang, Fuxu Wang
Low TYROBP expression predicts poor prognosis in multiple myeloma
Hong Luo, Chengyun Pan, Li Wang, Lin Zheng, Shuyun Cao, Xiuying Hu, Tianzhen Hu, Naiqin Zhao, Qin Shang, Jishi Wang
RBP7 functions as a tumor suppressor in HR + breast cancer by inhibiting the AKT/SREBP1 pathway and reducing fatty acid
Yue Yu, Zhihua Xu, Hao Zhou, Ruyan Xu, Jia Xu, Wenjun Liu, Yuxin Wu, Yue Qiu, Guangbo Zhang, Xue Huang, Yan Chen
The molecular characteristics could supplement the staging system of pT2/T3N0M0 esophageal squamous cell carcinoma: a translational study based on a cohort with over 20 years of follow-up
Wen-Mei Jiang, Jia-Yuan Tian, Yi-Han Guo, Li-Hong Qiu, Xing-Yu Luo, Yang-Yu Huang, Hao Long, Lan-Jun Zhang, Peng Lin, Xin-Xin Xu, Lei-Lei Wu, Guo-Wei Ma
The molecular subtyping and precision medicine in triple-negative breast cancer---based on Fudan TNBC classification
Lijuan Weng, Jianliang Zhou, Shenchao Guo, Nong Xu, Ruishuang Ma
Biological roles of SLC16A1-AS1 lncRNA and its clinical impacts in tumors
Bing Liao, Jialing Wang, Yalin Yuan, Hongliang Luo, Xi Ouyang
Immune cell infiltration and drug response in glioblastoma multiforme: insights from oxidative stress-related genes
Kan Wang, Yifei Xiao, Ruipeng Zheng, Yu Cheng
CCDC25 suppresses clear cell renal cell carcinoma progression by LATS1/YAP-mediated regulation of the hippo pathway
Hongpei Tan, Jiahao Liu, Yanan Li, Ze Mi, Baiying Liu, Pengfei Rong
Deciphering the prognostic features of bladder cancer through gemcitabine resistance and immune-related gene analysis and identifying potential small molecular drug PIK-75
Tingting Cai, Tao Feng, Guangren Li, Jin Wang, Shengming Jin, Dingwei Ye, Yiping Zhu
Correction to: N6‑methyladenosine levels in peripheral blood RNA: a potential diagnostic biomarker for colorectal cancer
Chunying Zhang, Jiadi Chen, Jingyi Ren, Xiaoyu Li, Yaqin Zhang, Bihan Huang, Yihan Xu, Luyan Dong, Yingping Cao
Comprehensive analyses of the cancer-associated fibroblast subtypes and their score system for prediction of outcomes and immunosuppressive microenvironment in prostate cancer
Ze Gao, Ning Zhang, Bingzheng An, Dawei Li, Zhiqing Fang, Dawei Xu
Retraction Note: TMED3 promotes cell proliferation and motility in breast cancer and is negatively modulated by miR-188-3p
Jing Pei, Jing Zhang, Xiaowei Yang, Zhengsheng Wu, Chenyun Sun, Zhaorui Wang, Benzhong Wang
MiR-380 inhibits the proliferation and invasion of cholangiocarcinoma cells by silencing LIS1
Zhicheng Wei, Bowen Xu, Yanjiang Yin, Jianping Chang, Zhiyu Li, Yefan Zhang, Xu Che, Xinyu Bi
Identification of fatty acids synthesis and metabolism-related gene signature and prediction of prognostic model in hepatocellular carcinoma
Ai Zhengdong, Xing Xiaoying, Fu Shuhui, Liang Rui, Tang Zehui, Song Guanbin, Yang Li, Tang Xi, Liu Wanqian
Enhancing therapeutic efficacy in luminal androgen receptor triple-negative breast cancer: exploring chidamide and enzalutamide as a promising combination strategy
Ya-Xin Zhao, Han Wang, Si-Wei Zhang, Wei-Xin Zhang, Yi-Zhou Jiang, Zhi-Ming Shao
The troglitazone derivative EP13 disrupts energy metabolism through respiratory chain complex I inhibition in breast cancer cells and potentiates the antiproliferative effect of glycolysis inhibitors
Claire Muller, Victorine Lacroix-Malgras, Jérôme Kluza, William Laine, Yonca Güler, Frédéric Bost, Michel Boisbrun, Sabine Mazerbourg, Stéphane Flament
Current challenges and therapeutic advances of CAR-T cell therapy for solid tumors
Tong Chen, Mingzhao Wang, Yanchao Chen, Yutao Liu
Micropeptides: potential treatment strategies for cancer
He Zhou, Yan Wu, Ji Cai, Dan Zhang, Dongfeng Lan, Xiaofang Dai, Songpo Liu, Tao Song, Xianyao Wang, Qinghong Kong, Zhixu He, Jun Tan, Jidong Zhang
Significance of PSCA as a novel prognostic marker and therapeutic target for cancer
Tina Nayerpour Dizaj, Abolfazl Doustmihan, Behnaz Sadeghzadeh Oskouei, Morteza Akbari, Mehdi Jaymand, MirAhmad Mazloomi, Rana Jahanban-Esfahlan
Pan-inhibition of the three H2S synthesizing enzymes restrains tumor progression and immunosuppression in breast cancer
Alyaa Dawoud, Rana A. Youness, Heba Nafea, Tamer Manie, Carole Bourquin, Csaba Szabo, Reham M. Abdel-Kader, Mohamed Z. Gad
Exosomes biogenesis was increased in metformin-treated human ovary cancer cells; possibly to mediate resistance
Reza Abbasi, Vahid Nejati, Jafar Rezaie
Comprehensive analysis of m6A modification in immune infiltration, metabolism and drug resistance in hepatocellular carcinoma
Yunxing Shi, Kai Li, Yichuan Yuan, Chenwei Wang, Zhiwen Yang, Dinglan Zuo, Yi Niu, Jiliang Qiu, Binkui Li, Yunfei Yuan, Wei He
A novel immunogenic cell death-related classification indicates the immune landscape and predicts clinical outcome and treatment response in acute myeloid leukemia
Fangmin Zhong, Shuyang He, Ni Guo, Luyi Shi, Linlin Zhang, Hua Jin, Guangyao Kong
Spatial and single-cell explorations uncover prognostic significance and immunological functions of mitochondrial calcium uniporter in breast cancer
Chia-Jung Li, Yen-Dun Tony Tzeng, Jui-Hu Hsiao, Ling-Ming Tseng, Tzu-Sheng Hsu, Pei-Yi Chu
Sparassis latifolia and exercise training as complementary medicine mitigated the 5-fluorouracil potent side effects in mice with colorectal cancer: bioinformatics approaches, novel monitoring pathological metrics, screening signatures, and innovative management tactic
Navid Abedpoor, Farzaneh Taghian, Khosro Jalali Dehkordi, Kamran Safavi
High LGALS3 expression induced by HCP5/hsa-miR-27b-3p correlates with poor prognosis and tumor immune infiltration in hepatocellular carcinoma
Yinghui Ren, Yongmei Qian, Qicheng Zhang, Xiaoping Li, Mingjiang Li, Wei Li, Pan Yang, Hengchang Ren, Hongxia Li, Yiqi Weng, Dengwen Li, Ke Xu, Wenli Yu
Unravelling immune microenvironment features underlying tumor progression in the single-cell era
Qilian Du, Qi An, Jiajun Zhang, Chao Liu, Qinyong Hu
Toxoplasma gondii suppresses proliferation and migration of breast cancer cells by regulating their transcriptome
Hengming Ye, Xiaotao Zhou, Bike Zhu, Tiantian Xiong, Weile Huang, Feng He, Hui Li, Lihua Chen, Luying Tang, Zefang Ren
PPP2R1A silencing suppresses LUAD progression by sensitizing cells to nelfinavir-induced apoptosis and pyroptosis
Yating Liu, Lianlian Ouyang, Shiyao Jiang, Lu Liang, Yuanbing Chen, Chao Mao, Yiqun Jiang, Li Cong
C6orf15 promotes liver metastasis via WNT/β-catenin signalling in colorectal cancer
Jiankang Yu, Jian Sun, Jingtong Tang, Jiayu Xu, Guanru Qian, Jianping Zhou
CDCA5-EEF1A1 interaction promotes progression of clear cell renal cell carcinoma by regulating mTOR signaling
Xun Wang, An Shi, Jie Liu, Wen Kong, Yiran Huang, Wei Xue, Fan Yang, Jiwei Huang
Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer
Lara Magni, Haoran Yu, Nynne M. Christensen, Mette H. Poulsen, Alexander Frueh, Ganga Deshar, Astrid Z. Johansen, Julia S. Johansen, Stephan A. Pless, Niklas R. Jørgensen, Ivana Novak
Identification of SUMOylation-related biomarkers in papillary thyroid carcinoma
Xiang Li, Zigang Ding, Yun Tong
Antitumor mechanisms and future clinical applications of the natural product triptolide
Shiwei Bao, Mei Yi, Bo Xiang, Pan Chen
Retraction Note: Circular RNA circ_0000517 regulates hepatocellular carcinoma development via miR-326/IGF1R axis
Shuwei He, Jianzeng Yang, Shitao Jiang, Yuan Li, Xingmin Han
circ-TFRC downregulation suppresses ovarian cancer progression via miR-615-3p/IGF2 axis regulation
Zhongxin Yan, Changling Duan, Xi Li, Hao Wang, Shanji Li, Xuexin Zhou, Yi Miao
Exosome-mediated secretion of miR-127-3p regulated by RAB27A accelerates metastasis in renal cell carcinoma
Dae Hyun Song, Jong Sil Lee, Jeong-Hee Lee, Dong Chul Kim, Jung Wook Yang, Min Hye Kim, Ji Min Na, Hyun-kyung Cho, Jiyun Yoo, Hyo Jung An
Retraction Note: MicroRNA-93-5p promotes epithelial-mesenchymal transition in gastric cancer by repressing tumor suppressor AHNAK expression
Erdong Shen, Xin Wang, Xin Liu, Mingyue Lv, Liang Zhang, Guolian Zhu, Zhe Sun
Retraction Note: Circular RNA ITCH suppressed prostate cancer progression by increasing HOXB13 expression via spongy miR-17-5p
Xuegang Wang, Rong Wang, Zhun Wu, Peide Bai
p53 activation enhances the sensitivity of non-small cell lung cancer to the combination of SH003 and docetaxel by inhibiting de novo pyrimidine synthesis
Yu-Jeong Choi, Kangwook Lee, Seo Yeon Lee, Youngbin Kwon, Jaehyuk Woo, Chan-Yong Jeon, Seong-Gyu Ko
Iron metabolism: backfire of cancer cell stemness and therapeutic modalities
Rong Yu, Yinhui Hang, Hsiang-i Tsai, Dongqing Wang, Haitao Zhu
Flavokawain C inhibits glucose metabolism and tumor angiogenesis in nasopharyngeal carcinoma by targeting the HSP90B1/STAT3/HK2 signaling axis
YuQiang Hu, ChenJie Yu, LiangJun Cheng, Chang Zhong, Jun An, MingZhen Zou, Bing Liu, Xia Gao
Polymorphism rs2327430 in TCF21 predicts the risk and prognosis of gastric cancer by affecting the binding between TFAP2A and TCF21
Xinyi Zhou, Kuan Shen, Shuqing Cao, Pengyu Li, Jian Xiao, Jiacheng Dong, Quan Cheng, Li Hu, Zekuan Xu, Li Yang
New insights into targeted therapy of glioblastoma using smart nanoparticles
Habib Ghaznavi, Reza Afzalipour, Samideh Khoei, Saman Sargazi, Sakine Shirvalilou, Roghayeh Sheervalilou
PD-L1 intrinsically promotes the proliferation of breast cancer cells through the SKP2-p27/p21 axis
Marwa Elfoly, Jumanah Y. Mirza, Ayodele Alaiya, Amal A. Al-Hazzani, Asma Tulbah, Monther Al-Alwan, Hazem Ghebeh
The m6A reader IGF2BP2 promotes esophageal cell carcinoma progression by enhancing EIF4A1 translation
Yuan Li, Zhuya Xiao, Yingying Wang, Daoming Zhang, Zuhua Chen
MicroRNA-34 and gastrointestinal cancers: a player with big functions
Wei Gao, Jianping Zhou, Mohammadamin Morshedi
Assessing the role of programmed cell death signatures and related gene TOP2A in progression and prognostic prediction of clear cell renal cell carcinoma
Qingshui Wang, Jiamin Liu, Ruiqiong Li, Simeng Wang, Yining Xu, Yawen Wang, Hao Zhang, Yingying Zhou, Xiuli Zhang, Xuequn Chen, Wei Zhuang, Yao Lin
Erianin inhibits the progression of triple-negative breast cancer by suppressing SRC-mediated cholesterol metabolism
Ming Li, Shiyao Kang, Xuming Deng, Huimin Li, Yuan Zhao, Wenru Tang, Miaomiao Sheng
Characterization of alternative splicing events and prognostic signatures in gastric cancer
Nan Zhu, Yupeng Zhao, Wenjing Yan, Lan Wei, Qingqing Sang, Jianfang Li, Bingya Liu, Beiqin Yu
A novel disulfide death-related genes prognostic signature identifies the role of IPO4 in glioma progression
HaoYuan Wu, ZhiHao Yang, ChenXi Chang, ZhiWei Wang, DeRan Zhang, QingGuo Guo, Bing Zhao
Forkhead box E1, frequently downregulted by promoter methylation, inhibits colorectal cancer cell growth and migration
Qinlan Shi, Zhongting Huang, Yeye Kuang, Chan Wang, Xiao Fang, Xiaotong Hu
MDM2: current research status and prospects of tumor treatment
Yumei Yao, Qian Zhang, Zhi Li, Hushan Zhang