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Journal of Cancer Research and Clinical Oncology

Issue 10/2023

Content (116 Articles)

Lung Cancer Research

Discovery of potential biomarkers for lung cancer classification based on human proteome microarrays using Stochastic Gradient Boosting approach

Ning Yao, Jianbo Pan, Xicheng Chen, Pengpeng Li, Yang Li, Zhenyan Wang, Tianhua Yao, Li Qian, Dong Yi, Yazhou Wu

Lung Cancer Research

Bleeding-related re-exploration following pulmonary resection: a report of a single-center experience

Shanbo Zheng, Ting Ye, Bin Li, Yang Zhang, Xiaoyang Luo, Hong Hu, Haiquan Chen

Metastasis Research

The prognostic role of HIF-1α and NF-κB expression in RAS wild-type metastatic colorectal cancer: A Turkish Oncology Group (TOG) study

Aykut Demirkıran, Fahriye Kılınç, Mehmet Zahid Koçak, Deniz Demirkıran, Mustafa Korkmaz, Melek Karakurt Eryılmaz, Murat Araz, Mustafa Karaağaç, Mehmet Artaç

Lung Cancer Research

Risk mapping of lung cancer: a comprehensive appraisal of published meta-analyses incorporating Mendelian randomization studies

Caichen Li, Jianfu Li, Shan Xiong, Huaqiang Zhou, Xiuyu Cai, Zhanhong Xie, Haoxin Peng, Xiangrong Wu, Ran Zhong, Yu Jiang, Zixuan Su, Feng Zhu, Zhenyu Huo, Bo Liu, Wenhao Chi, Huiting Wang, Yaokai Wen, Fan Ge, Yi Feng, Runchen Wang, Jiana Chen, Zisheng Chen, Jiang Shi, Bo Cheng, Zhuxing Chen, Hengrui Liang, Feng Li, Hongsheng Deng, Jianxing He, Wenhua Liang

Open Access Care Research

ePRO symptom follow-up of colorectal cancer patients receiving oxaliplatin-based adjuvant chemotherapy is feasible and enhances the quality of patient care: a prospective multicenter study

Sanna Iivanainen, Ravi Ravichandra, Antti Jekunen, Reetta Arokoski, Santeri Mentu, Laura Lang, Jussi Ekström, Henri Virtanen, Vesa Kataja, Jussi P. Koivunen

Inhibition of Polo-like kinase 1 (PLK1) triggers cell apoptosis via ROS-caused mitochondrial dysfunction in colorectal carcinoma

Ya Feng, Tianjiao Li, Zhoujun Lin, Yin Li, Xiao Han, Xiaolin Pei, Zhenkun Fu, Qiao Wu, Di Shao, Chenggang Li

Molecular phenotypic linkage between N6-methyladenosine methylation and tumor immune microenvironment in hepatocellular carcinoma

Feng Zhang, Junming Bi, Jiasheng Liao, Wenhui Zhong, Min Yu, Xin Lu, Jinhui Che, Zhiyuan Chen, Haobin Xu, Shixiong Hu, Yubin Liu, Shuijiao Guo

Open Access Metastasis Research

Dissecting the inflammatory tumor microenvironment of esophageal adenocarcinoma: mast cells and natural killer cells are favorable prognostic factors and associated with less extensive disease

Alyne Condurú dos Santos Cunha, Adrian Georg Simon, Thomas Zander, Reinhard Buettner, Christiane Josephine Bruns, Wolfgang Schroeder, Florian Gebauer, Alexander Quaas

Extracapsular extension of transitional zone prostate cancer miss-detected by multiparametric magnetic resonance imaging

Xin Chen, Wei Li, Jiajian Yang, Chen Huang, Chenchao Zhou, Yongchang Chen, Yuxin Lin, Jianquan Hou, Yuhua Huang, Xuedong Wei

Open Access Contraception Research

Ovarian cancer prevention by opportunistic salpingectomy is a new de facto standard in Germany

I. B. Runnebaum, A. Kather, J. Vorwergk, J. J. Cruz, A. R. Mothes, C. R. Beteta, J. Boer, M. Keller, M. Pölcher, A. Mustea, J. Sehouli

Open Access Sarcoma Research

Integrative analyses of bulk microarray data to discover genes, pathways, and immune infiltration characteristics associated with targeting of Ewing sarcoma

Binjie Cao, Haijian Sun, Zhehao Fan, Muhammad Babar Khawar, Liangliang Cai, Shiyi Yu, Zhengyan Liang, Dan Lv, Ning Wang, Caili Bi, Haibo Sun

Open Access Neutropenia Research

Individual hematotoxicity prediction of further chemotherapy cycles by dynamic mathematical models in patients with gastrointestinal tumors

Vivien Topf, Yuri Kheifetz, Severin Daum, Alexej Ballhausen, Andreas Schwarzer, Kien Vu Trung, Gertraud Stocker, Achim Aigner, Florian Lordick, Markus Scholz, Maren Knödler

Lung Cancer Research

The relationship of airflow limitation with lung squamous cell carcinoma: evidence from mendelian randomization analysis

Qing Zhang, Guannan Cai, Fei Cui, Feng Li, Hengrui Liang, Limei Gao, Wenwei Guo, Meihua Li, Ying Chen

Open Access Lymphoma Research

Whole body irradiation with intensity-modulated helical tomotherapy prior to haematopoietic stem cell transplantation: analysis of organs at risk by dose and its effect on blood kinetics

Mümtaz Köksal, Jonathan Baumert, Danny Jazmati, Felix Schoroth, Stephan Garbe, David Koch, Davide Scafa, Gustavo R. Sarria, Christina Leitzen, Gregor Massoth, Achilles Delis, Annkristin Heine, Tobias Holderried, Peter Brossart, Thomas Müdder, Leonard C. Schmeel

Anemia Research

Adverse outcomes and health-ecological influencing factors of preoperative frailty among elderly patients with gastric cancer

Lingyu Ding, Xueyi Miao, Xiaoman Jiang, Li Chen, Jinling Lu, Hanfei Zhu, Yinning Guo, Shuqin Zhu, Xinyi Xu, Jieman Hu, Qin Xu

Open Access Seminoma Research

Testicular neoplasms: the interrelationships of serum levels of microRNA-371a-3p (M371) and classical tumor markers with histology, clinical staging, and age—a statistical analysis

Klaus-Peter Dieckmann, Cansu Dumlupinar, Francesca Grobelny, Julia Utschig, Markus Klemke, El Moeiz Ahmed Saad, Christian Wülfing, Uwe Pichlmeier, Hendrik Isbarn, Gazanfer Belge

Rituximab Research

Survival outcomes of patients newly diagnosed with diffuse large B-cell lymphoma: real-world evidence from a German claims database

Peter Borchmann, Jan-Michel Heger, Jörg Mahlich, Michael S. Papadimitrious, Sybille Riou, Barbara Werner

Open Access Chronic Myeloid Leukemia Research

The interplay between telomeric complex members and BCR::ABL1 oncogenic tyrosine kinase in the maintenance of telomere length in chronic myeloid leukemia

Anna Deręgowska, Monika Pępek, Iwona Solarska, Marcin M. Machnicki, Katarzyna Pruszczyk, Marek Dudziński, Joanna Niesiobędzka-Krężel, Ilona Seferyńska, Waldemar Sawicki, Maciej Wnuk, Tomasz Stokłosa

Open Access Research

TOP-PIC: a new tool to optimize pharmacotherapy and reduce polypharmacy in patients with incurable cancer

Irene Strassl, Armin Windhager, Sigrid Machherndl-Spandl, Veronika Buxhofer-Ausch, Olga Stiefel, Ansgar Weltermann

Research

The significance of spread through air spaces in the prognostic assessment model of stage I lung adenocarcinoma and the exploration of its invasion mechanism

YangYang Niu, XinHao Han, Yuan Zeng, Abiyasi Nanding, Qiang Bai, SaiNan Guo, YaLi Hou, Yan Yu, QiuJu Zhang, XiaoMei Li

Open Access Endometrial Cancer Research

Overexpression of the orphan nuclear receptor NR2F6 is associated with improved survival across molecular subgroups in endometrial cancer patients

L. Proppe, T. Jagomast, S. Beume, L. Klapper, G. Gitas, F. Köster, S. Perner, A. Rody, J. Ribbat-Idel, L. C. Hanker

Lung Cancer Research

Standard deviation of CT radiomic features among malignancies in each individual: prognostic ability in lung cancer patients

Si Hongwei, Hao Xinzhong, Xu Huiqin, Xue Shuqin, Wang Ruonan, Li Li, Cao Jianzhong, Li Sijin

Open Access Lymphoma Research

Differential diagnosis of lymphoma with 18F-FDG PET/CT in patients with fever of unknown origin accompanied by lymphadenopathy

Jia Chen, Dong Xu, Wen-Jin Sun, Wen-Xia Wang, Na-Na Xie, Qiu-Rong Ruan, Jian-Xin Song

Open Access Primary Myelofibrosis Research

Diagnosis and treatment of MPN in real life: exploratory and retrospective chart review including 960 MPN patients diagnosed with ET or MF in Germany

Andreas Schmidt, Christiane Bernhardt, Dieter Bürkle, Stefan Fries, Carla V. Hannig, Kathleen Jentsch-Ullrich, Andreas Josting, Stephan Kreher, Marcel Reiser, Hans Tilman Steinmetz, Hans Tesch, Stephanie Terner, Alexander Schulte, Carl C. Crodel, Francesca Palandri, Florian H. Heidel

Research

Virtual screening reveals aprepitant to be a potent inhibitor of neutral sphingomyelinase 2: implications in blockade of exosome release in cancer therapy

Milad Moloudizargari, Shirin Hekmatirad, Sajjad Gharaghani, Ali Akbar Moghadamnia, Hossein Najafzadehvarzi, Mohammad Hossein Asghari

TIMP-2 as a predictive biomarker in 5-Fu-resistant colorectal cancer

Yaoqing Li, Chuchu Xu, Renjun Zhu, Liyijing Shen, Gengyuan Hu, Kelong Tao, Feng Tao, Zengxin Lu, Guolin Zhang

Neuroendocrine differentiation predicts the therapeutic efficacy of abiraterone and docetaxel as first-line therapy in metastatic castration-resistant prostate cancer

Nanwei Xu, Jinge Zhao, Fengnian Zhao, Haoyang Liu, Wenlian Yin, Sha Zhu, Ling Nie, Guangxi Sun, Linmao Zheng, Zhenhua Liu, Diming Cai, Junru Chen, Jindong Dai, Yuchao Ni, Zhipeng Wang, Xingming Zhang, Jiayu Liang, Yuntian Chen, Xu Hu, Xiuyi Pan, Xiaoxue Yin, Xudong Zhu, Yaowen Zhang, Zilin Wang, Yuhao Zeng, Minghao Wang, Pengfei Shen, Ni Chen, Hao Zeng

Open Access Lung Cancer Research

Low diffusion capacity predicts poor prognosis in extensive stage small cell lung cancer: a single-center analysis of 10 years

Jee Seon Kim, Eun Ji Kim, Jong Geol Jang, Kyung Soo Hong, June Hong Ahn

Metastasis Research

New insights into breast microcalcification for poor prognosis: NACT cohort and bone metastasis evaluation cohort

Yangling Hu, Lijuan Mao, Mengyi Wang, Zhenqiu Li, Meizhi Li, Chaoyang Wang, Lin Ji, Hui Zeng, Xiaoling Zhang

Open Access Breast Cancer Research

Female breast cancer subtypes in the Romagna Unit of the Emilia-Romagna cancer registry, and estimated incident cases by subtypes and age in Italy in 2020

Emanuele Crocetti, Alessandra Ravaioli, Orietta Giuliani, Lauro Bucchi, Rosa Vattiato, Silvia Mancini, Federica Zamagni, Benedetta Vitali, Chiara Balducci, Flavia Baldacchini, Fabio Falcini

Long non-coding RNA ENST00000503625 is a potential prognostic biomarker and metastasis suppressor gene in prostate cancer

Yaoming Li, Ziyu Fang, Silun Ge, Jingyi Li, Le Qu, Xiaolei Shi, Wei Zhang, Yinghao Sun, Shancheng Ren, Luofu Wang

Pretherapy investigations using highly robust visualized biomarkers from CT imaging by multiple machine-learning techniques toward its prognosis prediction for ALK-inhibitor therapy in NSCLC: a feasibility study

Jingjing Sun, Feng Li, Jiantao Yang, Chen Lin, Xianglan Zhou, Na Liu, Bingqian Zhang, Ge Song, Wenxian Wang, Chencui Huang, Zhengbo Song, Lei Shi

Lung Cancer Research

Antitumor effect of neoantigen-reactive T cells combined with PD1 inhibitor therapy in mouse lung cancer

Huan Qin, Haiyan Hu, Ximing Liao, Pei Zhao, Wenjuan He, Xiaoping Su, Jiaxing Sun, Qiang Li

Research

Machine learning-based immune prognostic model and ceRNA network construction for lung adenocarcinoma

Xiaoqian He, Ying Su, Pei Liu, Cheng Chen, Chen Chen, Haoqin Guan, Xiaoyi Lv, Wenjia Guo

Open Access NSCLC Research

 Concurrent/sequential versus sequential immune checkpoint inhibition in inoperable large stage III non-small cell lung cancer patients treated with chemoradiotherapy: a prospective observational study

Lukas Käsmann, Chukwuka Eze, Julian Taugner, Alexander Nieto, Kerstin Hofstetter, Sophie Kröninger, Julian Guggenberger, Saskia Kenndoff, Benedikt Flörsch, Amanda Tufman, Niels Reinmuth, Thomas Duell, Claus Belka, Farkhad Manapov

Open Access Cytostatic Therapy Research

GSTM1 and GSTT1 polymorphisms associated with pain in a chemotherapy-induced peripheral neuropathy cohort

Paul J. Dunn, Lyn R. Griffiths, Patsy Yates, Larisa M. Haupt, Kim E. Alexander

NSCLC Research

Targeted molecular profiling of solid tumours-Indian tertiary cancer centre experience

Mamta Gurav, Sridhar Epari, Prachi Gogte, Trupti Pai, Gauri Deshpande, Nupur Karnik, Omshree Shetty, Sangeeta Desai

Sumac-rose water mouthwash versus benzydamine to prevent radiation-induced oral mucositis in head and neck cancers: a phase II randomized trial

Ahmad Ameri, Ghazaleh Heydarirad, Rasoul Choopani, Sanaz Poshtmahi, Pooya Ameri, Fereshteh Talebi, Anahid Bagheri Pour, Farzad Taghizadeh-Hesary

Research

Adjuvant intravesical treatment in patients with intermediate and high-risk non-muscle-invasive bladder cancer with BCG versus MMC applied with COMBAT or EMDA. Results of a prospective study

Miguel Ángel Arrabal Polo, María Teresa Melgarejo Segura, Yaiza Yáñez Castillo, Ana Morales Martínez, Manuel Pareja Vílchez, Miguel Arrabal Martín

Open Access Metastasis Research

Gastrointestinal stromal tumors of the upper GI tract: population-based analysis of epidemiology, treatment and outcome based on data from the German Clinical Cancer Registry Group

Thaer S. A. Abdalla, Lina Pieper, Markus Kist, Michael Thomaschewski, Monika Klinkhammer-Schalke, Sylke Ruth Zeissig, Kees Kleihues-van Tol, Ulrich Friedrich Wellner, Tobias Keck, Richard Hummel

Open Access Melanoma Research

Impact of the COVID-19 pandemic on reported cancer diagnoses in Bavaria, Germany

Sven Voigtländer, Amir Hakimhashemi, Nina Grundmann, Martin Radespiel-Tröger, Elisabeth C. Inwald, Olaf Ortmann, Michael Gerken, Stefanie J. Klug, Monika Klinkhammer-Schalke, Martin Meyer, Jacqueline Müller-Nordhorn

Open Access Mastectomy Research

Differences among a Portuguese cohort of BRCA pathogenic/likely pathogenic variants carriers choosing risk-reducing mastectomy or intensive breast surveillance

Sandra Torres, Bárbara Peleteiro, André Magalhães, Luzia Garrido, Susy Costa, José Luís Fougo

Open Access Research

Cytokeratin 6 identifies basal-like subtypes of pancreatic ductal adenocarcinoma with decreased survival

Su Ir Lyu, Thaddaeus Krey, Alexander I. Damanakis, Yue Zhao, Christiane J. Bruns, Thomas Schmidt, Felix C. Popp, Alexander Quaas, Karl Knipper, Michael Heise, Frank Marusch, Marco Siech, Tawfik Mosa, Bodo Schniewind, Jürgen Tepel, Werner Hartwig, Christoph Prinz, Bettina M. Rau, Marco Niedergethmann, Rainer Kube, George Saada, Wolfgang Hiller, Utz Settmacher

Clinical outcomes of immune checkpoint inhibitors in unresectable or metastatic combined hepatocellular–cholangiocarcinoma

Yoon Jung Jang, Eo Jin Kim, Hyung-Don Kim, Kyu-Pyo Kim, Min-Hee Ryu, Sook Ryun Park, Won-Mook Choi, Danbi Lee, Jonggi Choi, Ju Hyun Shim, Kang Mo Kim, Young-Suk Lim, Han Chu Lee, Baek-Yeol Ryoo, Changhoon Yoo

Open Access Neuroendocrine Tumor Research

Analyses of sex-based clinicopathological differences among patients with gastrointestinal neuroendocrine neoplasms in Europe

Henning Jann, Sarah Krieg, Andreas Krieg, Johannes Eschrich, Tom Luedde, Karel Kostev, Sven Loosen, Christoph Roderburg

Survival outcomes from atezolizumab plus bevacizumab versus Lenvatinib in Child Pugh B unresectable hepatocellular carcinoma patients

Margherita Rimini, Mara Persano, Toshifumi Tada, Goki Suda, Shigeo Shimose, Masatoshi Kudo, Jaekyung Cheon, Fabian Finkelmeier, Ho Yeong Lim, José Presa, Francesca Salani, Sara Lonardi, Fabio Piscaglia, Takashi Kumada, Naoya Sakamoto, Hideki Iwamoto, Tomoko Aoki, Hong Jae Chon, Vera Himmelsbach, Marta Schirripa, Margarida Montes, Caterina Vivaldi, Caterina Soldà, Atsushi Hiraoka, Takuya Sho, Takashi Niizeki, Naoshi Nishida, Christoph Steup, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi, Shinya Fukunishi, Kunihiko Tsuji, Toru Ishikawa, Kazuto Tajiri, Hironori Ochi, Satoshi Yasuda, Hidenori Toyoda, Chikara Ogawa, Takashi Nishimura, Takeshi Hatanaka, Satoru Kakizaki, Noritomo Shimada, Kazuhito Kawata, Fujimasa Tada, Hideko Ohama, Kazuhiro Nouso, Asahiro Morishita, Akemi Tsutsui, Takuya Nagano, Norio Itokawa, Tomomi Okubo, Taeang Arai, Michitaka Imai, Hisashi Kosaka, Atsushi Naganuma, Yohei Koizumi, Shinichiro Nakamura, Masaki Kaibori, Hiroko Iijima, Yoichi Hiasa, Valentina Burgio, Mario Scartozzi, Stefano Cascinu, Andrea Casadei-Gardini

Open Access Colorectal Cancer Research

Decreased expression of prolyl hydroxylase 1 is associated with poor prognosis in colorectal cancers

Nathaniel Melling, Julia Grass, Matthias Reeh, Michael Tachezy, Marco Blessmann, Jakob R. Izbicki, Katharina Grupp

Open Access Nephrectomy Research

Long non-coding RNAs enable precise diagnosis and prediction of early relapse after nephrectomy in patients with renal cell carcinoma

Julia Bohosova, Katerina Kozelkova, Dagmar Al Tukmachi, Karolina Trachtova, Ondrej Naar, Michaela Ruckova, Eva Kolarikova, Michal Stanik, Alexandr Poprach, Ondrej Slaby

Open Access Cancer Therapy Research

Relevance of tumor boards for the inclusion of patients in oncological clinical trials

Hendrik Dapper, Maurice Dantes, Peter Herschbach, Hana Algül, Volker Heinemann

Open Access Ovarian Cancer Research

Pazopanib with Topotecan weekly for patients with platinum-resistant or intermediate-sensitive recurrent ovarian cancer: results of a multicentre, open label phase I/II study (TOPAZ)

Radoslav Chekerov, Tjadina Arndt, Klaus Pietzner, Ulrich Canzler, Pauline Wimberger, Hans-Georg Strauß, Sven Mahner, Linn Woelber, Nikolaus de Gregorio, Gertraud Stocker, Ekkehard von Abel, Tanja Neunhoeffer, Antje Kristina Belau, Alexander Mustea, Isil Yalinkaya, Elena Ioana Braicu, Rolf Richter, Jalid Sehouli

Open Access Cytostatic Therapy Research

Microsatellite instability and sex-specific differences of survival in gastric cancer after neoadjuvant chemotherapy without and with taxane: An observational study in real world patients

Theresa Hiltner, Meike Kohlruss, Anna-Lina Herz, Sylvie Lorenzen, Alexander Novotny, Alexander Hapfelmeier, Moritz Jesinghaus, Julia Slotta-Huspenina, Leila Sisic, Matthias M. Gaida, Wilko Weichert, Katja Ott, Gisela Keller

Open Access Gastrectomy Research

Two decades of gastric and gastroesophageal junction cancer surgery

Patrick S. Plum, Aylin Pamuk, Atakan G. Barutcu, Christoph Mallmann, Emanuel Niesen, Felix Berlth, Thomas Zander, Seung-Hun Chon, Stefan P. Moenig, Alexander Quaas, Christiane J. Bruns, Arnulf H. Hoelscher, Hakan Alakus

Open Access Prostate Cancer Research

Mitotic phosphorylation of Tau/MAPT modulates cell cycle progression in prostate cancer cells

Letizia Clementi, Samantha Sabetta, Veronica Zelli, Chiara Compagnoni, Alessandra Tessitore, Vincenzo Mattei, Adriano Angelucci

Research

YAP inhibitor verteporfin suppresses tumor angiogenesis and overcomes chemoresistance in esophageal squamous cell carcinoma

Xue-Wei Wang, Rong Zhao, Zi-Yi Yang, Ting Li, Jia-Cheng Yang, Xiu-Li Wang, Xin-Ting Li, Xin-Ran Zhao, Xiao-Zhong Li, Xiao-Xia Wang

Open Access Positron Emission Tomography Research

Single-centre experience with peptide receptor radionuclide therapy for neuroendocrine tumours (NETs): results using a theranostic molecular imaging-guided approach

S. Gordon, D. L. H. Chan, E. J. Bernard, M. E. Eslick, K. P. Willowson, P. J. Roach, A. F. Engel, R. Maher, S. J. Clarke, V. Agarwal, L. Yasmin, M. De Silva, S. Mascall, A. Conner, D. Nevell, N. Pavlakis, D. L. Bailey

Open Access Human Papillomavirus Research

β-CATENIN is a positive prognostic marker for HPV-positive head and neck squamous cell carcinoma

Stefan Stoiber, Faris F. Brkic, Tobias Maier, Julia Schnoell, Elisabeth Gurnhofer, Gregor Heiduschka, Lorenz Kadletz-Wanke, Lukas Kenner

Invasiveness assessment by artificial intelligence against intraoperative frozen section for pulmonary nodules ≤ 3 cm

Ze-Rui Zhao, Ying-Hong Yu, Zhi-Chao Lin, De-Hua Ma, Yao-Bin Lin, Jian Hu, Qing-Quan Luo, Gao-Feng Li, Chun Chen, Yu-Lun Yang, Jian-Cheng Yang, Yong-Bin Lin, Hao Long

Cetuximab Research

Development of 177Lu-Cetuximab-PAMAM dendrimeric nanosystem: a novel theranostic radioimmunoconjugate

Seyed Mohammad Hosseini, Javad Mohammadnejad, Hassan Yousefnia, Behrouz Alirezapour, Ali Hossein Rezayan

Effects of immunosuppressive treatment on patient outcomes after immune checkpoint inhibitor-related gastrointestinal toxicity

Malek Shatila, Weijie Ma, Yantong Cui, Sidra Naz, Anusha S. Thomas, Enrico N. De Toni, Helga-Paula Török, Najib Ben Khaled, Mehmet Altan, Bryan Schneider, Yinghong Wang

Metastasis Research

Prognostic effect of CD73 in pancreatic ductal adenocarcinoma for disease-free survival after radical surgery

Dailei Qin, Ran Wei, Kewei Huang, Ruiqi Wang, Honglu Ding, Zehui Yao, Pu Xi, Shengping Li

Maintenance therapy with Fluoropyrimidine and cetuximab or bevacizumab after first line FOLFOX-chemotherapy in metastatic colorectal cancer according to RAS or BRAFV600E mutation status

Sora Kang, Myung-Won Lee, Ik-Chan Song, Hyo-Jin Lee, Hwan-Jung Yun, Deog-Yeon Jo, Jung Sun Kim, Jung Hye Kwon, Ji-Yeon Kim, Kyung-Ha Lee, Hyewon Ryu

Lung Cancer Research

Day surgery unit robotics thoracic surgery: feasibility and management

Xin Li, Yuanqi Liu, Yanwu Zhou, Yang Gao, Chaojun Duan, Chunfang Zhang

Open Access Cholangiocarcinoma Research

Optical coherence tomography combined with convolutional neural networks can differentiate between intrahepatic cholangiocarcinoma and liver parenchyma ex vivo

Laura I. Wolff, Enno Hachgenei, Paul Goßmann, Mariia Druzenko, Maik Frye, Niels König, Robert H. Schmitt, Alexandros Chrysos, Katharina Jöchle, Daniel Truhn, Jakob Nikolas Kather, Andreas Lambertz, Nadine T. Gaisa, Danny Jonigk, Tom F. Ulmer, Ulf P. Neumann, Sven A. Lang, Iakovos Amygdalos

The colon inflammatory index score can predict the survival outcome after resection of colorectal cancer: a retrospective multicentre study

Takahiko Akiyama, Yuji Miyamoto, Akihisa Matsuda, Ryuma Tokunaga, Katsuhiro Ogawa, Masaaki Iwatsuki, Shiro Iwagami, Yoshifumi Baba, Naoya Yoshida, Hiromichi Sonoda, Takeshi Yamada, Hiroshi Yoshida, Hideo Baba

Review

Clinical and economic impact of clinical oncology pharmacy in cancer patients receiving injectable anticancer treatments: a systematic review

Claire Lattard, Amandine Baudouin, Virginie Larbre, Chloé Herledan, Ariane Cerutti, Marie-Anne Cerfon, Reine Kimbidima, Anne-Gaelle Caffin, Nicolas Vantard, Vérane Schwiertz, Florence Ranchon, Catherine Rioufol

Review

BIN1 in cancer: biomarker and therapeutic target

Si-yu Chen, Jin-long Cao, Kun-peng Li, Shun Wan, Li Yang

CXC chemokine receptor 4 (CXCR4) blockade in cancer treatment

Shunshun Bao, Mohammad Darvishi, Ali H Amin, Maysoon T. Al-Haideri, Indrajit Patra, Khadisha Kashikova, Irfan Ahmad, Fahad Alsaikhan, Zahraa Haleem Al-qaim, Moaed E. Al-Gazally, Bahman Abedi Kiasari, Bahareh Tavakoli-Far, Akmal A. Sidikov, Yasser Fakri Mustafa, Reza Akhavan-Sigari

Targeting adipocyte–immune cell crosstalk to control breast cancer progression

Weihua Wang, Hongdan Chen, Supeng Yin, Zeyu Yang, Fan Zhang

Open Access Artificial Intelligence Review

An overview and a roadmap for artificial intelligence in hematology and oncology

Wiebke Rösler, Michael Altenbuchinger, Bettina Baeßler, Tim Beissbarth, Gernot Beutel, Robert Bock, Nikolas von Bubnoff, Jan-Niklas Eckardt, Sebastian Foersch, Chiara M. L. Loeffler, Jan Moritz Middeke, Martha-Lena Mueller, Thomas Oellerich, Benjamin Risse, André Scherag, Christoph Schliemann, Markus Scholz, Rainer Spang, Christian Thielscher, Ioannis Tsoukakis, Jakob Nikolas Kather

Open Access Cytokines Review

Characterization of immunomodulatory factors and cells in bronchoalveolar lavage fluid for immune checkpoint inhibitor-related pneumonitis

Peng-Mei Wang, Zhong-Wei Zhang, Shan Zhang, Qian Xing, Zhi-Yong Zhao, Qiong-Hua Lin, Li-Hua Shen, Zhi-Li Xia, Fang-Fang Li, Biao Zhu

Parasites as potential targets for cancer immunotherapy

Morteza Yousefi, Mohammadesmail Akbari, Mahboubeh hadipour, Azar Balouti Dehkordi, Zohreh Farahbakhsh, Hossein Yousofi Darani

Open Access Shock Review

Heat shock protein 90 (HSP90) inhibitors in gastrointestinal cancer: where do we currently stand?—A systematic review

Christian Tibor Josef Magyar, Yogesh K. Vashist, Deborah Stroka, Corina Kim-Fuchs, Martin D. Berger, Vanessa M. Banz

Small molecule inhibitors for cancer metabolism: promising prospects to be explored

Dan Liu, HongPing Wang, XingXing Li, JiFang Liu, YanLing Zhang, Jing Hu

Review

An update in the applications of exosomes in cancer theranostics: from research to clinical trials

Kourosh Shahraki, Paria Ghasemi Boroumand, Hajie Lotfi, Fatemeh Radnia, Hossein Shahriari, Saman Sargazi, Sedigheh Sadat Mortazavi, Milad Shirvaliloo, Sakine Shirvalilou, Roghayeh Sheervalilou

Open Access Epigenetics Review

Cancer immune escape: the role of antigen presentation machinery

Anoop Kallingal, Mateusz Olszewski, Natalia Maciejewska, Wioletta Brankiewicz, Maciej Baginski

Shedding light on macrophage immunotherapy in lung cancer

Huiyun Ma, Zhouwei Zhang, Qin Hu, Hongyu Chen, Gujie Wu, Youlang Zhou, Qun Xue

Open Access Gastric Cancer Review

The role of Pcdh10 in neurological disease and cancer

Yilan Zhen, Macarena Pavez, Xinying Li

Open Access Ultrasound Correction

Correction to: Nanotechnology-augmented sonodynamic therapy and associated immune-mediated effects for the treatment of pancreatic ductal adenocarcinoma

Marym Mohammad Hadi, Sian Farrell, Heather Nesbitt, Keith Thomas, Ilona Kubajewska, Alex Ng, Hamzah Masood, Shiv Patel, Fabiola Sciscione, Brian Davidson, John F. Callan, Alexander J. MacRobert, Anthony P. McHale, Nikolitsa Nomikou

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.