Issue 1/2022
Content (147 Articles)
Qingwei San treats oral ulcer subjected to stomach heat syndrome in db/db mice by targeting TLR4/MyD88/NF-κB pathway
Lu Shi, Yongcheng An, Long Cheng, Yiyang Li, Huimin Li, Chen Wang, Yinglan Lv, Yuhui Duan, Hongyu Dai, Changhao He, Huilin Zhang, Yan Huang, Wanxin Fu, ShengPeng Wang, Baosheng Zhao, Yitao Wang, Yonghua Zhao
Repurposing a clinically approved prescription Colquhounia root tablet to treat diabetic kidney disease via suppressing PI3K/AKT/NF-kB activation
Zhaochen Ma, Yudong Liu, Congchong Li, Yanqiong Zhang, Na Lin
Compound traditional Chinese medicine dermatitis ointment ameliorates inflammatory responses and dysregulation of itch-related molecules in atopic dermatitis
Rongrong Zhang, Hongyin Zhang, Shuai Shao, Yingxin Shen, Fengqin Xiao, Jiaming Sun, Songlan Piao, Daqing Zhao, Guangzhe Li, Mingming Yan
Differential action of pro-angiogenic and anti-angiogenic components of Danhong injection in ischemic vascular disease or tumor models
Shuang He, Rongrong Chen, Li Peng, Zhenzuo Jiang, Haixin Liu, Zihao Chen, Tiechan Zhao, John Owoicho Orgah, Jie Ren, Peng Zhang, Yuefei Wang, Xiumei Gao, Yan Zhu
Market access of Chinese patent medicine products to healthcare security system in China: implications for international integration of traditional medicine into health systems
Chenglai Xia, Dongning Yao, Yunfeng Lai, Yan Xue, Hao Hu
Clinical and economic analysis of Gastrodin injection for dizziness or vertigo: a retrospective cohort study based on electronic health records in China
Yunfeng Lai, Ruoning Wang, Wei Li, He Zhu, Shuyang Fei, Honghao Shi, Nan Lu, Carolina Oi Lam Ung, Hao Hu, Sheng Han
Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages
Lin Cao, Erjin Xu, Rendong Zheng, Zhili Zhangchen, Rongling Zhong, Fei Huang, Juan Ye, Hongping Sun, Yaofu Fan, Shaofeng Xie, Yu Chen, Yijiao Xu, Jing Cao, Wen Cao, Chao Liu
Acupuncture for cancer pain: an evidence-based clinical practice guideline
Long Ge, Qi Wang, Yihan He, Darong Wu, Qi Zhou, Nenggui Xu, Kehu Yang, Yaolong Chen, Anthony Lin Zhang, Haiqing Hua, Jinchang Huang, Ka-Kit Hui, Fanrong Liang, Linpeng Wang, Bin Xu, Yufei Yang, Weimin Zhang, Baixiao Zhao, Bing Zhu, Xinfeng Guo, Charlie Changli Xue, Haibo Zhang, Charlie Changli Xue, Haibo Zhang, Xinfeng Guo, Darong Wu, Kehu Yang, Yaolong Chen, Long Ge, Runsen He, Haiqing Hua, Jinchang Huang, Ka-Kit Hui, Fanrong Liang, Zuodi Pan, Linpeng Wang, Bin Xu, Nenggui Xu, Yufei Yang, Anthony Lin Zhang, Weimin Zhang, Baixiao Zhao, Bing Zhu, Qi Wang, Yihan He, Qi Zhou, Lihong Yang, Shaonan Liu, Jieyun Li, Liangying Hou, Qian Zhang, Honghao Lai, Xueling Chen, Xueyi Deng, Fuqin Kang
Echinacoside exhibits antidepressant-like effects through AMPAR–Akt/ERK–mTOR pathway stimulation and BDNF expression in mice
Han-Wen Chuang, Tse-Yen Wang, Chih-Chia Huang, I-Hua Wei
Correction to: Effect of mineral excipients on processing traditional Chinese medicines: an insight into the components, pharmacodynamics and mechanism
Yan Liu, Xiaojie Li, Cai Chen, Aijing Leng, Jialin Qu
Astragalus membranaceus (Huangqi) and Rhizoma curcumae (Ezhu) decoction suppresses colorectal cancer via downregulation of Wnt5/β-Catenin signal
Yong Bian, Gang Wang, Jing Zhou, Gang Yin, Tiantian Liu, Li Liang, Xinyue Yang, Wen Zhang, Kexin Ni, Decai Tang, Yun Yu
A review on the applications of Traditional Chinese medicine polysaccharides in drug delivery systems
Bei Wang, Xianfeng Wang, Zhiwei Xiong, Guanzheng Lu, Weikun Ma, Qinglin Lv, Long Wang, Xiaobin Jia, Liang Feng
Bioactivities and mechanisms of natural medicines in the management of pulmonary arterial hypertension
Zhijie Yu, Jun Xiao, Xiao Chen, Yi Ruan, Yang Chen, Xiaoyuan Zheng, Qiang Wang
Comparison of blood tonic efficacy and chemical constituents of Kadsura interior A.C. Smith and its closely related species
Jing Xu, Jiushi Liu, Bin Li, Xueping Wei, Yaodong Qi, Bengang Zhang, Haitao Liu, Peigen Xiao
Dianthi herba: a comprehensive review of its botany, traditional use, phytochemistry, and pharmacology
Qian Liu, Er-Huan Zang, Cong-Cong Wang, Yu-Chao Liu, Hui Niu, Yuan Gao, Min-Hui Li
Chinese herbal medicine treatment based on subgroup differentiation as adjunct therapy for Parkinson’s disease: study protocol of a pilot add-on, randomised, controlled, pragmatic clinical trial
Sam Chun Sum Yuen, Ka Kit Chua, Linda L. D. Zhong, Kam Wa Chan, Conrad Kwan Ho Chan, Kam Leung Chan, Zhixiu Lin, Vincent Mok, Alexander Y. Lau, Min Li
Red yeast rice ameliorates non-alcoholic fatty liver disease through inhibiting lipid synthesis and NF-κB/NLRP3 inflammasome-mediated hepatic inflammation in mice
Jian Zou, Chunyan Yan, Jian-Bo Wan
Toddalolactone protects against osteoarthritis by ameliorating chondrocyte inflammation and suppressing osteoclastogenesis
Yiming Xu, Song Xue, Tian Zhang, Xinmeng Jin, Cong Wang, Haiming Lu, Yiming Zhong, Hongjie Chen, Libo Zhu, Jinzhong Ma, Weilin Sang
Combination of pseudoephedrine and emodin ameliorates LPS-induced acute lung injury by regulating macrophage M1/M2 polarization through the VIP/cAMP/PKA pathway
Wen-Ba Wang, Jing-Tao Li, Yi Hui, Jie Shi, Xu-Yan Wang, Shu-Guang Yan
Effect of traditional chinese medicine (TCM) and its fermentation using Lactobacillus plantarum on ceftriaxone sodium-induced dysbacteriotic diarrhea in mice
Xin Guo, Zipeng Yan, Jixiang Wang, Xinfeng Fan, Jie Kang, Ruiyan Niu, Zilong Sun
Mineral medicine: from traditional drugs to multifunctional delivery systems
Xiaoqing Zhong, Zhenning Di, Yuanxin Xu, Qifan Liang, Kuanhan Feng, Yuting Zhang, Liuqing Di, Ruoning Wang
Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis
Xuling Li, Tingting Zhao, Junling Gu, Zhe Wang, Jing Lin, Rushang Wang, Tingting Duan, Zhenghai Li, Ruixue Dong, Weiming Wang, Kin-Fong Hong, Zhilong Liu, Wenbo Huang, Dingkun Gui, Hua Zhou, Youhua Xu
Revealing potential anti-fibrotic mechanism of Ganxianfang formula based on RNA sequence
Zongyi Liu, Huanyu Xiang, Dejuan Xiang, Shuang Xiao, Hongyan Xiang, Jing Xiao, Hong Ren, Peng Hu, Huabao Liu, Mingli Peng
Cucurbitacin B inhibits TGF-β1-induced epithelial–mesenchymal transition (EMT) in NSCLC through regulating ROS and PI3K/Akt/mTOR pathways
Renyikun Yuan, Qiumei Fan, Xiaowei Liang, Shan Han, Jia He, Qin-Qin Wang, Hongwei Gao, Yulin Feng, Shilin Yang
Ginkgo biloba leaf extract mitigates cisplatin-induced chronic renal interstitial fibrosis by inhibiting the epithelial-mesenchymal transition of renal tubular epithelial cells mediated by the Smad3/TGF-β1 and Smad3/p38 MAPK pathways
Congying Wei, Yansong Zhang, Xiaobin Zhong, Sisi Lu, Xiaoqin Zou, Yufang Yang, Songqing Huang, Zhenguang Huang
Improvement of polydopamine-loaded salidroside on osseointegration of titanium implants
Qingqing Yi, Pengchen Liang, Dongyu Liang, Liou Cao, Shuang Sha, Xinquan Jiang, Qing Chang
Tea and tea drinking: China’s outstanding contributions to the mankind
Si-Yuan Pan, Qu Nie, Hai-Chuan Tai, Xue-Lan Song, Yu-Fan Tong, Long-Jian-Feng Zhang, Xue-Wei Wu, Zhao-Heng Lin, Yong-Yu Zhang, Du-Yun Ye, Yi Zhang, Xiao-Yan Wang, Pei-Li Zhu, Zhu-Sheng Chu, Zhi-Ling Yu, Chun Liang
Cucurbitacin E inhibits cellular proliferation and induces apoptosis in melanoma by suppressing HSDL2 expression
Wen-Bei Liu, He-Li Wang, Lei Chen, Biao Tang, Guolin Ke, Shuai Wang, Yin-Qiao Sun, Junting Ma, Da-Lun Lyu
Key quality factors for Chinese herbal medicines entering the EU market
Mei Wang, Pei-Fen Yao, Peng-Yue Sun, Wen Liang, Xiao-Jia Chen
Efficacy and mechanisms of traditional Chinese medicine for COVID-19: a systematic review
Xiaomin Kang, De Jin, Linlin Jiang, Yuqing Zhang, Yuehong Zhang, Xuedong An, Liyun Duan, Cunqing Yang, Rongrong Zhou, Yingying Duan, Yuting Sun, Fengmei Lian
A pilot randomized placebo-controlled study on modified MaZiRenWan: a formulated Chinese medicine to relieve constipation for palliative cancer patients
Chung-wah Cheng, Hoi-fung Mok, Cora W. S. Yau, Jasmine T. M. Chan, Yu-chen Kang, Pui-yan Lam, Linda L. D. Zhong, Chen Zhao, Bacon F. L. Ng, Annie O. L. Kwok, Doris M. W. Tse, Zhao-xiang Bian
An integrated study of Violae Herba (Viola philippica) and five adulterants by morphology, chemical compositions and chloroplast genomes: insights into its certified plant origin
Gengyu Lu, Juanjuan Qiao, Long Wang, Hui Liu, Gang Wu, Yan Zhu, Yucheng Zhao, Guoyong Xie, Minjian Qin
CRISPR-Cas gene editing technology and its application prospect in medicinal plants
Miaoxian Guo, Hongyu Chen, Shuting Dong, Zheng Zhang, Hongmei Luo
α-Mangostin inhibits LPS-induced bone resorption by restricting osteoclastogenesis via NF-κB and MAPK signaling
Wenkan Zhang, Guangyao Jiang, Xiaozhong Zhou, Leyi Huang, Jiahong Meng, Bin He, Yiying Qi
The application of mass spectrometry imaging in traditional Chinese medicine: a review
Lieyan Huang, Lixing Nie, Zhong Dai, Jing Dong, Xiaofei Jia, Xuexin Yang, Lingwen Yao, Shuang-cheng Ma
Cinnamomi Ramulus inhibits the growth of colon cancer cells via Akt/ERK signaling pathways
Boyu Pan, Yafei Xia, Zilu Gao, Gang Zhao, Liangjiao Wang, Senbiao Fang, Liren Liu, Shu Yan
NMR-based metabonomics reveals the dynamic effect of electro-acupuncture on central nervous system in gastric mucosal lesions (GML) rats
Miaosen Huang, Yiwei Peng, Qida He, Linyu Lian, Yichen Wang, Longbin Zhang, Yuan Zhang, Jiacheng Shen, Zongbao Yang
Strategies for molecular authentication of herbal products: from experimental design to data analysis
Hoi-Yan Wu, Pang-Chui Shaw
Anti-inflammatory effects of anemonin on acute ulcerative colitis via targeted regulation of protein kinase C-θ
Lu Jiang, Chunhua Chi, Fang Yuan, Meiqi Lu, Dongqing Hu, Lin Wang, Xiaoming Liu
Liushen Capsules, a promising clinical candidate for COVID-19, alleviates SARS-CoV-2-induced pulmonary in vivo and inhibits the proliferation of the variant virus strains in vitro
Qinhai Ma, Biao Lei, Ruihan Chen, Bin Liu, Wencong Lu, Haiming Jiang, Zexing Chen, Xiaowen Guo, Yutao Wang, Lu Zhang, Qiaoyan Chen, Xiaobo Li, Zifeng Yang
From non-targeted to targeted GC–MS metabolomics strategy for identification of TCM preparations containing natural and artificial musk
Meng Ding, Jun-Li Fan, Dong-Fang Huang, Yue Jiang, Meng-Ning Li, Yu-Qing Zheng, Xiao-Ping Yang, Ping Li, Hua Yang
Ludangshen oral liquid for treatment of convalescent COVID-19 patients: a randomized, double-blind, placebo-controlled multicenter trial
Xuedong An, Bo Peng, Xiaodong Huang, Hongmei Jiang, Zhang’e Xiong, Hong Zhang, Fengmei Lian, Yuanming Ba, Xiaolin Tong
Chinese herbal medicines in the treatment of ulcerative colitis: a review
Xuan Zhang, Lin Zhang, Jacky C. P. Chan, Xihong Wang, Chenchen Zhao, Ying Xu, Weifeng Xiong, Wai Chak Chung, Feng Liang, Xu Wang, Jiangxia Miao, Zhaoxiang Bian
Investigating the mechanism of Xian-ling-lian-xia-fang for inhibiting vasculogenic mimicry in triple negative breast cancer via blocking VEGF/MMPs pathway
Feifei Li, Youyang Shi, Yang Zhang, Xiaojuan Yang, Yi Wang, Kexin Jiang, Ciyi Hua, Chunyu Wu, Chenping Sun, Yuenong Qin, Sheng Liu
Plant metabolomics: a new strategy and tool for quality evaluation of Chinese medicinal materials
Qi Xiao, Xinlu Mu, Jiushi Liu, Bin Li, Haitao Liu, Bengang Zhang, Peigen Xiao
Correlation between quality and geographical origins of Leonuri Herba revealed by the qualitative fingerprint profiling and quantitative determination of chemical components
Kelly Yinching Lam, Yinghao Wang, Tszking Lam, Chuenfai Ku, Wingping Yeung, Zhongzhen Zhao
Development of software enabling Chinese medicine-based precision treatment for osteoporosis at the gene and pathway levels
Jinyu Li, Guiyu Feng, Haoyang He, Haolin Wang, Jia Tang, Aiqing Han, Xiaohong Mu, Weifeng Zhu
Three-dimensional visualization of electroacupuncture-induced activation of brown adipose tissue via sympathetic innervation in PCOS rats
Hongru Gao, Xiaoyu Tong, Wei Hu, Yicong Wang, Kuinyu Lee, Xiaoqing Xu, Jiemei Shi, Zhenle Pei, Wenhan Lu, Yuning Chen, Ruonan Zhang, Zheyi Wang, Ziyu Wang, Chengzhi Han, Yu Wang, Yi Feng
A clinical randomized controlled trial: moxibustion at Laogong interval with Panax notoginseng promoted the maturation of arteriovenous fistulae
Yurou Chen, Lin Xu, Di Huang, Dongping Chen, Feng Wu, Luobing Wang, Jie Zhou, Tianying Lan, Xuehua Qin, Chaoyang Ye
Fuzzy identification of bioactive components for different efficacies of rhubarb by the back propagation neural network association analysis of UPLC-Q-TOF/MSE and integrated effects
Jia-Qian Chen, Yan-Yan Chen, Xia Du, Hui-Juan Tao, Zong-Jin Pu, Xu-Qin Shi, Shi-Jun Yue, Gui-Sheng Zhou, Er-Xin Shang, Yu-Ping Tang, Jin-Ao Duan
Angong Niuhuang Wan reduces hemorrhagic transformation and mortality in ischemic stroke rats with delayed thrombolysis: involvement of peroxynitrite-mediated MMP-9 activation
Hansen Chen, Yunxia Luo, Bun Tsoi, Bing Gu, Suhua Qi, Jiangang Shen
Acupuncture at Neiguan suppresses PVCs occurring post-myocardial infarction by alleviating inflammation and fibrosis
Hao Hong, Xin Cao, Tian Deng, Xiang-Min Meng, Yu-Meng Li, Li-Juan Zhu, Jing Lv, Xuan Li, Shu-Guang Yu, Bing-Mei Zhu
Phytochemicals targeting Toll-like receptors 4 (TLR4) in inflammatory bowel disease
Wenbin Dai, Longhai Long, Xiaoqiang Wang, Sen Li, Houping Xu
Influence of different pretreatments and drying methods on the chemical compositions and bioactivities of Smilacis Glabrae Rhizoma
Juanjuan Qiao, Gengyu Lu, Gang Wu, Hui Liu, Wanli Wang, Tianmao Zhang, Guoyong Xie, Minjian Qin
Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy
Shuang Zhang, Yu Dong, Xiuping Chen, Chris Soon Heng TAN, Min Li, Kai Miao, Jia-Hong Lu
Rubus chingii Hu. unripe fruits extract ameliorates carbon tetrachloride-induced liver fibrosis and improves the associated gut microbiota imbalance
Jianjun Wu, Dingqi Zhang, Bo Zhu, Siqi Wang, Yongbin Xu, Congcong Zhang, Hailing Yang, Shunchun Wang, Ping Liu, Luping Qin, Wei Liu
Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis
Wenchuan Qi, Xiang Li, Yanrong Ren, Xueying Liu, Hongjuan Fu, Xiao Wang, Xiao Li, Jian Xiong, Qianhua Zheng, Dingjun Cai, Fanrong Liang
Developing an artificial intelligence method for screening hepatotoxic compounds in traditional Chinese medicine and Western medicine combination
Zhao Chen, Mengzhu Zhao, Liangzhen You, Rui Zheng, Yin Jiang, Xiaoyu Zhang, Ruijin Qiu, Yang Sun, Haie Pan, Tianmai He, Xuxu Wei, Zhineng Chen, Chen Zhao, Hongcai Shang
Pharmacological activities and molecular mechanisms of Pulsatilla saponins
Jinmiao Zhong, Lihua Tan, Meiwan Chen, Chengwei He
Saikosaponin D exerts antidepressant effect by regulating Homer1-mGluR5 and mTOR signaling in a rat model of chronic unpredictable mild stress
Chen-Yue Liu, Jian-Bei Chen, Yue-Yun Liu, Xue-Ming Zhou, Man Zhang, You-Ming Jiang, Qing-Yu Ma, Zhe Xue, Zong-Yao Zhao, Xiao-Juan Li, Jia-Xu Chen
Microbial spore genetic marker technology, a potential technology for traditional Chinese medicine traceability system
Dazhong Zhao, Zunzhe Tian, Jing Cai, Juan He
Metabolomics analyses of traditional Chinese medicine formula Shuang Huang Lian by UHPLC-QTOF-MS/MS
Gang Xu, Yachun Shu, Yan Xu
Alpinetin promotes hair regeneration via activating hair follicle stem cells
Xiaojiao Fan, Jing Chen, Yajun Zhang, Siyi Wang, Wenqian Zhong, Huipu Yuan, Xia Wu, Chaochen Wang, Yixin Zheng, Yuan Wei, Ying Xiao
Reporting quality of sham needles used as controls in acupuncture trials: a methodological evaluation
Ye-Seul Lee, Song-Yi Kim, Mariah Kim, Minseo Kim, Jiyoon Won, Hyangsook Lee, Myeong Soo Lee, Younbyoung Chae
Persimmon leaf extract alleviates chronic social defeat stress-induced depressive-like behaviors by preventing dendritic spine loss via inhibition of serotonin reuptake in mice
Hui Yu, Shumin Shao, Junnan Xu, Haibiao Guo, Zhangfeng Zhong, Jiangping Xu
Inhibitory effect of Isatis tinctoria L. water extract on DNCB-induced atopic dermatitis in BALB/c mice and HaCaT cells
Ga-Yul Min, Tae In Kim, Ji-Hye Kim, Won-Kyung Cho, Ju-Hye Yang, Jin-Yeul Ma
Effects of acupuncture at acupoints with lower versus higher pain threshold for knee osteoarthritis: a multicenter randomized controlled trial
Jiali Liu, Ying Li, Ling Li, Xiaochao Luo, Ning Li, Xuguang Yang, Hongxing Zhang, Zhibin Liu, Deying Kang, Yanan Luo, Yanmei Liu, Yulong Jia, Yan Ren, Minghong Yao, Yuning Wang, Jin Chen, Mewujia Maiji, Kang Zou, Ling Zhao, Fanrong Liang, Xin Sun
Traditional Chinese medicine syndrome differentiation and treatment by stages of Parkinson’s disease: study protocol for a multicentre, randomized, double-blind, placebo-controlled clinical trial
Yuqing Hu, Sichun Gu, Xiaolei Yuan, Hui Li, Canxing Yuan, Qing Ye
Crowberry inhibits cell proliferation and migration through a molecular mechanism that includes inhibition of DEK and Akt signaling in cholangiocarcinoma
Xue Wang, Xuebing Zhou, Ludan Zhang, Xin Zhang, Chunyu Yang, Yingshi Piao, Jinhua Zhao, Lili Jin, Guihua Jin, Renbo An, Xiangshan Ren
Serum biomarker-based osteoporosis risk prediction and the systemic effects of Trifolium pratense ethanolic extract in a postmenopausal model
Yixian Quah, Jireh Chan Yi-Le, Na-Hye Park, Yuan Yee Lee, Eon-Bee Lee, Seung-Hee Jang, Min-Jeong Kim, Man Hee Rhee, Seung-Jin Lee, Seung-Chun Park
Serum metabolomics analysis of deficiency pattern and excess pattern in patients with rheumatoid arthritis
Bin Liu, Hongtao Guo, Li Li, Qi Geng, Ning Zhao, Yong Tan, Zhixing Nie, Guilin Ouyang, Aiping Lu, Cheng Lu
A strategy for quality control of ginkgo biloba preparations based on UPLC fingerprint analysis and multi-component separation combined with quantitative analysis
Li-na Liu, Hong-yu Jin, Zan Ke, Wei-yi Xu, Lei Sun, Shuang-cheng Ma
Geniposide suppresses NLRP3 inflammasome-mediated pyroptosis via the AMPK signaling pathway to mitigate myocardial ischemia/reperfusion injury
Haiyan Li, Dong-Hua Yang, Yanmei Zhang, Fuchun Zheng, Fenfei Gao, Jiajia Sun, Ganggang Shi
Inflammatory bowel disease: an overview of Chinese herbal medicine formula-based treatment
Shuo Yuan, Qi Wang, Jiao Li, Jia-Chen Xue, You Li, Huan Meng, Xiao-Ting Hou, Ji-Xing Nan, Qing-Gao Zhang
Panax notoginseng extract and total saponin suppress diet-induced obesity and endoplasmic reticulum stress in epididymal white adipose tissue in mice
Yi Tan, Xutao Zhang, Yan Zhou, Lingchao Miao, Baojun Xu, Haroon Khan, Yitao Wang, Hua Yu, Wai San Cheang
Metabolomics and integrated network pharmacology analysis reveal SNKAF decoction suppresses cell proliferation and induced cell apoptisis in hepatocellular carcinoma via PI3K/Akt/P53/FoxO signaling axis
Wei Guo, Xiaohui Yao, Siyuan Lan, Chi Zhang, Hanhan Li, Zhuangzhong Chen, Ling Yu, Guanxian Liu, Yuan Lin, Shan Liu, Hanrui Chen
The efficacy and safety of combined chinese herbal medicine and western medicine therapy for COVID-19: a systematic review and meta-analysis
Lu Li, Hongliang Xie, Ling Wang, Aolin Zhang, Xuan Mou, Yifan Lin, Hongli Ma, Yu Wang, Jian Li, Jingshu Gao, Chi Chiu Wang, Ping Chung Leung, Xiaohui Fan, Xiaoke Wu
Jin-Tian-Ge ameliorates ovariectomy-induced bone loss in rats and modulates osteoblastogenesis and osteoclastogenesis in vitro
Yi Shen, Na Wang, Qi Zhang, Yuling Liu, Qudi Wu, Yuqiong He, Yang Wang, Xiaoyan Wang, Qiming Zhao, Quanlong Zhang, Luping Qin, Qiaoyan Zhang
Fecal fermentation characteristics of Rheum tanguticum polysaccharide and its effect on the modulation of gut microbial composition
Ding-Tao Wu, Qin Yuan, Kang-Lin Feng, Jinming Zhang, Ren-You Gan, Liang Zou, Shengpeng Wang
Artificial intelligence-directed acupuncture: a review
Yulin Wang, Xiuming Shi, Thomas Efferth, Dong Shang
3,3′-Diindolylmethane improves antitumor immune responses of PD-1 blockade via inhibiting myeloid-derived suppressor cells
Qi Sun, Lin Xiao, Zhiying Cui, Yaping Yang, Junting Ma, Zhen Huang, Junfeng Zhang, Jiangning Chen
Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ1-42-induced Alzheimer’s disease mice and glutamate-injured HT22 cells
Sixia Yang, Zeping xie, Tingting Pei, Yi zeng, Qiaowu Xiong, Hui Wei, Yong Wang, Weidong Cheng
Asafoetida exerts neuroprotective effect on oxidative stress induced apoptosis through PI3K/Akt/GSK3β/Nrf2/HO-1 pathway
Qianqian Huang, Chen Zhang, Shi Dong, Junwen Han, Sihao Qu, Tianshu Xie, Haibin Zhao, Yuanyuan Shi
Predicting for anti-(mutant) SARS-CoV-2 and anti-inflammation compounds of Lianhua Qingwen Capsules in treating COVID-19
Liang Hong, Min He, Shaoping Li, Jing Zhao
Bu Shen Huo Xue decoction promotes functional recovery in spinal cord injury mice by improving the microenvironment to promote axonal regeneration
Yonghui Hou, Dan Luo, Yu Hou, Jiyao Luan, Jiheng Zhan, Zepeng Chen, Shunmei E, Liangliang Xu, Dingkun Lin
Traditional Chinese medicine promotes bone regeneration in bone tissue engineering
Zheng-Rong Gao, Yun-Zhi Feng, Ya-Qiong Zhao, Jie Zhao, Ying-Hui Zhou, Qin Ye, Yun Chen, Li Tan, Shao-Hui Zhang, Yao Feng, Jing Hu, Ze-Yue Ou-Yang, Marie Aimee Dusenge, Yue Guo
Efficacy and safety of modified Xiao-Feng Powder in the treatment of chronic urticaria: protocol of a randomized double-blind placebo-controlled study
Hing Yu Hung, Tianhe Song, Steven King Fan Loo, Kam Leung Chan, Jessica Yuet Ling Ching, Chi Him Sum, Louis Cho Wing Lo, Sarah Chon Pin Chia, Ray Tin Muk Ho, Pui Kuan Cheong, Tony Hon Chung Siu, Ka Chun Leung, Zhi-Xiu Lin
An anti-inflammatory and anti-fibrotic proprietary Chinese medicine nasal spray designated as Allergic Rhinitis Nose Drops (ARND) with potential to prevent SARS-CoV-2 coronavirus infection by targeting RBD (Delta)- angiotensin converting enzyme 2 (ACE2) binding
Ka Man Yip, Kwan Ming Lee, Tzi Bun Ng, Shujun Xu, Ken Kin Lam Yung, Shaogang Qu, Allen Ka Loon Cheung, Stephen Cho Wing Sze
Integrated strategy of network analysis prediction and experimental validation to elucidate the possible mechanism of compound Turkish gall ointment in treating eczema
Xuan Ma, Meng Hao, Ming Hui Zhang, Ya Zeng, Qing Qing Yang, Lu Zhao, Chen Yang Fan, Zhi Hong Ji, Ke Ao Li, Zhi Jian Li, Mirzat Maimaiti, Ji Hong Nie
Frontier progress of the combination of modern medicine and traditional Chinese medicine in the treatment of hepatocellular carcinoma
Lai Wei, Zeyu Wang, Niancai Jing, Yi Lu, Jili Yang, Hongyu Xiao, Huanyu Guo, Shoukun Sun, Mingjing Li, Daqing Zhao, Xiangyan Li, Wenxiu Qi, Yue Zhang
Astragalus mongholicus Bunge and Curcuma aromatica Salisb. inhibits liver metastasis of colon cancer by regulating EMT via the CXCL8/CXCR2 axis and PI3K/AKT/mTOR signaling pathway
Fuyan Liu, Yan Liang, Ruolan Sun, Weicheng Yang, Zhongqing Liang, Junfei Gu, Fan Zhao, Decai Tang
Acupuncture combined with auricular acupressure for smoking cessation and its effects on tobacco dependence and smoking behavior among Hong Kong smokers: a multicenter pilot clinical study
Lai Fun Ho, Wai Kwan Ho, Ling Ling Wong, Sze Wan Chiu, Shuk Yu Tang, Chun Ming Wong, Kin San Chan, Chi Lan Lam, Min Chen, Kam Leung Chan, Guohua Lin, Bacon Fung-Leung Ng, Zhi Xiu Lin
The inhibitory effect and mechanism of Yi-qi-hua-yu-jie-du decoction on the drug resistance of gastric cancer stem cells based on ABC transporters
Wenjie Huang, Fang Wen, Peixing Gu, Jiatong Liu, Yun Xia, Ye Li, Jiayu Zhou, Siyuan Song, Shuai Ruan, Suping Gu, Xiaoxue Chen, Peng Shu
Comparison of ONT and CCS sequencing technologies on the polyploid genome of a medicinal plant showed that high error rate of ONT reads are not suitable for self-correction
Peng Zeng, Zunzhe Tian, Yuwei Han, Weixiong Zhang, Tinggan Zhou, Yingmei Peng, Hao Hu, Jing Cai
Isoflavones daidzin and daidzein inhibit lipopolysaccharide-induced inflammation in RAW264.7 macrophages
Yi Tan, Xutao Zhang, Wai San Cheang
Therapeutic material basis and underling mechanisms of Shaoyao Decoction-exerted alleviation effects of colitis based on GPX4-regulated ferroptosis in epithelial cells
Juan Li, Xiangge Tian, Jinming Liu, Yuying Mo, Xiaoyi Guo, Yang Qiu, Yuejian Liu, Xiaochi Ma, Yan Wang, Yongjian Xiong
Effects of steam on polysaccharides from Polygonatum cyrtonema based on saccharide mapping analysis and pharmacological activity assays
Zherui Chen, Baojie Zhu, Zhixin Chen, Wen Cao, Junqiao Wang, Shaoping Li, Jing Zhao
Natural products: potential drugs for the treatment of renal fibrosis
Zijun Zhou, Yanheng Qiao, Yanru Zhao, Xin Chen, Jie Li, Hanqing Zhang, Qiumei Lan, Bo Yang
Effects of Chinese medicine for COVID-19 rehabilitation: a multicenter observational study
Linda Li-Dan Zhong, Yi-Ping Wong, Chor-Yin Leung, Bo Peng, Zhi-Xiu Lin, Vivian Chi-Woon Wong Taam, Yi Luo, Hai-Yong Chen, Chao-Dong Chao, Chor-Fung Wong, Freddie Shung-Chi Tam, Kui Chan, Kwan-Yiu Lee, Lai-Fun Ho, Alan Yat-Lun Wong, Chi-Fung Choy, Bacon Fung-Leung Ng, Rowena How-Wan Wong, Yi-Bin Feng, Ching Liong, Zhao-Xiang Bian
Propolis: An update on its chemistry and pharmacological applications
Rajib Hossain, Cristina Quispe, Rasel Ahmed Khan, Abu Saim Mohammad Saikat, Pranta Ray, Damira Ongalbek, Balakyz Yeskaliyeva, Divya Jain, Antonella Smeriglio, Domenico Trombetta, Roghayeh Kiani, Farzad Kobarfard, Naheed Mojgani, Parvaneh Saffarian, Seyed Abdulmajid Ayatollahi, Chandan Sarkar, Mohammad Torequl Islam, Dılhun Keriman, Arserim Uçar, Miquel Martorell, Antoni Sureda, Gianfranco Pintus, Monica Butnariu, Javad Sharifi-Rad, William C. Cho
Quantification of prevalence, clinical characteristics, co-existence, and geographic variations of traditional Chinese medicine diagnostic patterns via latent tree analysis-based differentiation rules among functional dyspepsia patients
Leonard Ho, Yulong Xu, Nevin L. Zhang, Fai Fai Ho, Irene X. Y. Wu, Shuijiao Chen, Xiaowei Liu, Charlene H. L. Wong, Jessica Y. L. Ching, Pui Kuan Cheong, Wing Fai Yeung, Justin C. Y. Wu, Vincent C. H. Chung
Traditional Chinese Medicine Fufang-Zhenzhu-Tiaozhi capsule prevents renal injury in diabetic minipigs with coronary heart disease
Lixia Song, Ke Wang, Jianying Yin, Yiqi Yang, Bo Li, Dongxing Zhang, Hong Wang, Weixuan Wang, Wenjing Zhan, Caijuan Guo, Zhanhui Gu, Lexun Wang, Zhihuan Zeng, Weijian Bei, Xianglu Rong, Jiao Guo
Quality assessment and Q-markers discovery of Tongsaimai tablet by integrating serum pharmacochemistry and network pharmacology for anti-atherosclerosis benefit
Yanfen Cheng, Meng Xiao, Jiamei Chen, Di Wang, Yichen Hu, Chenfeng Zhang, Tuanjie Wang, Chaomei Fu, Yihan Wu, Jinming Zhang
Weipiling decoction alleviates N-methyl-N-nitro-N′-nitrosoguanidine-induced gastric precancerous lesions via NF-κB signalling pathway inhibition
Penghui Yang, Hongmei Yang, Hengli Zhou, Qiuyue Li, Sufen Wei, Qi Wang, Yan Yan, Yongqiang Liu, Huafeng Pan, Siyi Li
Comprehensive chemical profiling of volatile constituents of Angong Niuhuang Pill in vitro and in vivo based on gas chromatography coupled with mass spectrometry
Yue Jiang, Jie Li, Meng Ding, Zi-Fan Guo, Hua Yang, Hui-Jun Li, Wen Gao, Ping Li
Traditional Chinese medicine paraffin therapy: an evidence-based overview from a modern medicine perspective
Wenxi Yan, Lanping Liu, Tao Yang, Xiaochen Yang
Integrating pharmacokinetics and network analysis to investigate the mechanism of Moutan Cortex in blood-heat and blood stasis syndrome
Qiuli Ye, Ying Zhang, Donghui Yan, Yue Sun, Ming Li, Hui Cao, Shumei Wang, Jiang Meng
Potential role of tea drinking in preventing hyperuricaemia in rats: biochemical and molecular evidence
Siyao Sang, Lufei Wang, Taotao Liang, Mingjie Su, Hui Li
The “whole ingredients extract” of Astragali Radix improves the symptoms of dextran sulfate sodium-induced ulcerative colitis in mice through systemic immunomodulation
Ke-Gang Linghu, Qiushuo Ma, Shi-Hang Xiong, Mingming Zhao, Qiling Chen, Wen Xu, Meiwan Chen, Jian-Ye Zhang, Yuanjia Hu, Wei Xu, Hua Yu
An intersectional analysis of LncRNAs and mRNAs reveals the potential therapeutic targets of Bi Zhong Xiao Decoction in collagen-induced arthritis rats
Cailin He, Yang Wang, Yuqi Wen, Teng Li, En Hu, Siqing Zeng, Bo Yang, Xingui Xiong
Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia
Yuanpei Lian, Maomao Zhu, Bing Yang, Xianfeng Wang, Jingqi Zeng, Yanjun Yang, Shuchen Guo, Xiaobin Jia, Liang Feng
DNA barcoding: an efficient technology to authenticate plant species of traditional Chinese medicine and recent advances
Shuang Zhu, Qiaozhen Liu, Simin Qiu, Jiangpeng Dai, Xiaoxia Gao
Medicinal and edible plants in the treatment of dyslipidemia: advances and prospects
Ying Hu, Xingjuan Chen, Mu Hu, Dongwei Zhang, Shuo Yuan, Ping Li, Ling Feng
Eryngium caeruleum: an update on ethnobotany, phytochemistry and biomedical applications
Dmitryi Alexeevich Konovalov, Edgardo Avendaño Cáceres, Ekaterina Aleksandrovna Shcherbakova, Jesús Herrera-Bravo, Deepak Chandran, Miquel Martorell, Muzaffar Hasan, Manoj Kumar, Saad Bakrim, Abdelhakim Bouyahya, William C. Cho, Javad Sharifi-Rad, Hafiz A. R. Suleria, Daniela Calina
Nitidine chloride induces caspase 3/GSDME-dependent pyroptosis by inhibting PI3K/Akt pathway in lung cancer
Fei Yu, Weidan Tan, Zhiquan Chen, Xiaoju Shen, Xiaoxiang Mo, Xiaocheng Mo, Jingchuan He, Zhihua Deng, Jie Wang, Zhuo Luo, Jie Yang
Poria cocos polysaccharides exert prebiotic function to attenuate the adverse effects and improve the therapeutic outcome of 5-FU in ApcMin/+ mice
Lin Yin, Guoxin Huang, Imran Khan, Lu Su, Wenrui Xia, Betty Yuen Kwan Law, Vincent Kam Wai Wong, Qiang Wu, Jingyi Wang, Wai Kit Leong, W. L. Wendy Hsiao
Metabolic profiling and pharmacokinetic studies of Baihu-Guizhi decoction in rats by UFLC-Q-TOF–MS/MS and UHPLC-Q-TRAP-MS/MS
Yan He, Zhenkun Zhou, Weijie Li, Yanqiong Zhang, Ruoyao Shi, Tao Li, Linlin Jin, Hongliang Yao, Na Lin, Hao Wu
Understanding the tonifying and the detoxifying properties of Chinese medicines from their impacts on gut microbiota and host metabolism: a case study with four medicinal herbs in experimental colitis rat model
Ting Li, Xuejiao Gao, Zhixiang Yan, Tai-Seng Wai, Wei Yang, Junru Chen, Ru Yan
Combination of curcumin and piperine synergistically improves pain-like behaviors in mouse models of pain with no potential CNS side effects
Pawana Boonrueng, Peththa Wadu Dasuni Wasana, Hasriadi, Opa Vajragupta, Pornchai Rojsitthisak, Pasarapa Towiwat
Correction: Effects of Chinese medicine for COVID-19 rehabilitation: a multicenter observational study
Linda Li-Dan Zhong, Yi-Ping Wong, Chor-Yin Leung, Bo Peng, Zhi-Xiu Lin, Vivian Chi-Woon Wong Taam, Yi Luo, Hai-Yong Chen, Chao-Dong Chao, Chor-Fung Wong, Freddie Shung-Chi Tam, Kui Chan, Kwan-Yiu Lee, Lai-Fun Ho, Alan Yat-Lun Wong, Chi-Fung Choy, Bacon Fung-Leung Ng, Rowena How-Wan Wong, Yi-Bin Feng, Ching Liong, Zhao-Xiang Bian
Correction: Natural products: potential drugs for the treatment of renal fibrosis
Zijun Zhou, Yanheng Qiao, Yanru Zhao, Xin Chen, Jie Li, Hanqing Zhang, Qiumei Lan, Bo Yang
Effectiveness and safety research of Qingfei Paidu (QFPD) in treatment of COVID-19: an up-to-date systematic review and meta-analysis
Xinxin Wang, Tao Ma, Wei Zhang, Qiang Chu
Lipidomics combined with transcriptomic and mass spectrometry imaging analysis of the Asiatic toad (Bufo gargarizans) during metamorphosis and bufadienolide accumulation
Bo Sun, Shan Jiang, Mingli Li, Yan Zhang, Yanyan Zhou, Xiaolu Wei, Hongjie Wang, Nan Si, Baolin Bian, Haiyu Zhao
Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice
Shiyu Zhang, Yinxiao Mi, Tingting Ye, Xiaoyan Lu, Li Liu, Jing Qian, Xiaohui Fan
Chemometrics integrated with in silico pharmacology to reveal antioxidative and anti-inflammatory markers of dandelion for its quality control
Feng-Jie Liu, Jiao Yang, Xu-Yan Chen, Ting Yu, Hui Ni, Liang Feng, Ping Li, Hui-Jun Li
The tibetan medicine Zuozhu-Daxi can prevent Helicobacter pylori induced-gastric mucosa inflammation by inhibiting lipid metabolism
Yanyan Shi, Jing Ning, Kelsang Norbu, Xingzi Hou, Huiling Zheng, Hejun Zhang, Wei Yu, Feng Zhou, Yuan Li, Shigang Ding, Qingying Zhang
Traditional Chinese medicine injections: where we are after 80-year development
Wenwen Zheng, Yiyang Wu, Hanlu Gao, Defang Ouyang
Zishen Pill alleviates diabetes in Db/db mice via activation of PI3K/AKT pathway in the liver
You Wu, Boju Sun, Xiaoyuan Guo, Lili Wu, Yaomu Hu, Lingling Qin, Tao Yang, Mei Li, Tianyu Qin, Miao Jiang, Tonghua Liu
Integrated dose–response metabolomics with therapeutic effects and adverse reactions may demystify the dosage of traditional Chinese medicine
Yan-Yan Chen, Jia-Qian Chen, Yu-Ping Tang, Er-Xin Shang, Qi Zhao, Jun-Bo Zou, Ding-Qiao Xu, Shi-Jun Yue, Jie Yang, Rui-Jia Fu, Gui-Sheng Zhou, Jin-Ao Duan
Integrated metabolomics, network pharmacology and biological verification to reveal the mechanisms of Nauclea officinalis treatment of LPS-induced acute lung injury
Han Xu, Sicong Xu, Liyan Li, Yuhuang Wu, Shiying Mai, Yiqiang Xie, Yinfeng Tan, Ailing Li, Fengming Xue, Xiaoning He, Yonghui Li
Identification of potential immunomodulators from Pulsatilla decoction that act on therapeutic targets for ulcerative colitis based on pharmacological activity, absorbed ingredients, and in-silico molecular docking
Li-rong Deng, Qian Han, Min Zou, Fang-jun Chen, Chang-yin Huang, Yi-ming Zhong, Qian-yan Wu, Brian Tomlinson, Yan-hong Li
Exploration of the mechanisms underlying the beneficial effect of Luo Tong formula on retinal function in diabetic rats via the “gut microbiota–inflammation–retina” axis
Sha Di, Chensi Yao, Liping Qiao, Xiuyang Li, Bing Pang, Jiaran Lin, Jia Wang, Min Li, Xiaolin Tong
Xinyang Tablet attenuates chronic hypoxia-induced right ventricular remodeling via inhibiting cardiomyocytes apoptosis
An-Ran Gao, Shuo Li, Xiao-Cui Tan, Ting Huang, Hua-Jin Dong, Rui Xue, Jing-Cao Li, Yang Zhang, You-Zhi Zhang, Xiao Wang
Pharmacokinetic study of the main components of Tanreqing capsules and Tanreqing injections in beagles by liquid chromatography–tandem mass spectrometry
Lili Cui, Liang Wang, Deduo Xu, Zhipeng Wang, Yong Chen, Xinhua Song, Fengjing Xu, Shouhong Gao, Lifeng Huang, Xia Tao, Wansheng Chen
Taxillus chinensis (DC.) Danser: a comprehensive review on botany, traditional uses, phytochemistry, pharmacology, and toxicology
Mi Qin, Qianqian Huang, Xin Yang, Lu Yu, Yong Tang, Chunxiang Zhang, Dalian Qin, Wenjun Zou, Junzhu Deng, Jian Liu, Haiyang Hu, Long Wang, Anguo Wu, Jianming Wu
Semisynthetic aurones A14 protects against T-cell acute lymphoblastic leukemia via suppressing proliferation and inducing cell cycle arrest with apoptosis
Meng Wang, Lisi Li, Tengyun Fan, Lixue Cao, Jiayi Zhang, Shuang Li, Chunming Liu, Xifu Liu
Chinese integrated guideline on the management of gastric precancerous conditions and lesions
Ping Wang, Peng Li, Yingxuan Chen, Li Li, Yuanyuan Lu, Weixun Zhou, Liqun Bian, Beihua Zhang, Xiaolan Yin, Junxiang Li, Jie Chen, Shutian Zhang, Yongquan Shi, Xudong Tang
Chaihu-Guizhi-Ganjiang Decoction is more efficacious in treating irritable bowel syndrome than Dicetel according to metabolomics analysis
Mingming Li, Jiawei Zhu, Xuan Liu, Zhiying Dong, Jigui Tang, Cian Zhang, Jianpeng Jiao, Jiani Chen, Fenghao Yin, Shi Qiu, Feng Zhang, Shouhong Gao, Zhipeng Wang, Xia Tao, Xiaoqiang Yue, Lianna Sun, Wansheng Chen
Effects of Shenling Baizhu powder on pyrotinib-induced diarrhea: analysis of gut microbiota, metabonomics, and network pharmacology
Jingjiang Lai, Fengxian Jiang, Xiaoli Zhuo, Xiaoying Xu, Lei Liu, Ke Yin, Jingliang Wang, Jing Zhao, Wei Xu, Hongjing Liu, Xuan Wang, Wen Jiang, Ke Wang, Shuping Yang, Honglin Guo, Fanghua Qi, Xiaotian Yuan, Xiaoyan Lin, Guobin Fu
Nauclea officinalis: A Chinese medicinal herb with phytochemical, biological, and pharmacological effects
Bin Liu, Qi Geng, Zhiwen Cao, Li Li, Peipei Lu, Lin Lin, Lan Yan, Cheng Lu
Chinese herbal compound prescriptions combined with Chinese medicine powder based on traditional Chinese medicine syndrome differentiation for treatment of chronic atrophic gastritis with erosion: a multi-center, randomized, positive-controlled clinical trial
Tai Zhang, Beihua Zhang, Jinkang Xu, Shunping Ren, Shaogang Huang, Zhaohong Shi, Shaoju Guo, Liqun Bian, Ping Wang, Fengyun Wang, Yidong Cai, Xudong Tang
Integrating network pharmacology, UPLC-Q–TOF–MS and molecular docking to investigate the effect and mechanism of Chuanxiong Renshen decoction against Alzheimer's disease
Zhuo Jun Shen, Yun Bo Fu, Jin Ling Hou, Lu Ning Lin, Xiao Yan Wang, Chang Yu Li, Yuan Xiao Yang
Divergent impacts on the gut microbiome and host metabolism induced by traditional Chinese Medicine with Cold or Hot properties in mice
Bingbing Li, Xin Tao, Lili Sheng, Yan Li, Ningning Zheng, Houkai Li
Dicoumarol: from chemistry to antitumor benefits
Vera L. M. Silva, Rita Silva-Reis, Alexandra Moreira-Pais, Tiago Ferreira, Paula A. Oliveira, Rita Ferreira, Susana M. Cardoso, Javad Sharifi-Rad, Monica Butnariu, Maria Alina Costea, Ioana Grozea
Effect of ginsenoside compound K on alleviating colitis via modulating gut microbiota
Li Wang, Li Shao, Man-Yun Chen, Lin Wang, Wei Zhang, Feng-Bo Tan, Wei-Hua Huang
Isolation, bioassay and 3D-QSAR analysis of 8-isopentenyl flavonoids from Epimedium sagittatum maxim. as PDE5A inhibitors
Juntao Li, Yue Wu, Xinxin Yu, Xinyu Zheng, Jiechen Xian, Senjie Li, Wanyin Shi, Yun Tang, Zhe-Sheng Chen, Guixia Liu, Shen Yao, Jian Xu, Xiangwei Zheng