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Knee Osteoarthritis 

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  1. Open Access 01-12-2024 | Knee Osteoarthritis | OriginalPaper

    Efficacy of Mulligan joint mobilizations and trunk stabilization exercises versus isometric knee strengthening in the management of knee osteoarthritis: a randomized controlled trial

    Knee osteoarthritis (KOA) is a progressive degenerative joint disease characterized by symptoms such as knee stiffness, swelling, and loss of function. The symptoms tend to worsen over time, resulting in decreased walking speed and difficulties in …

  2. Open Access 26-04-2024 | Knee Osteoarthritis | Online First

    Does pain intensity after total knee arthroplasty depend on somatosensory functioning in knee osteoarthritis patients? A prospective cohort study

    The objective of this study is to determine whether the change in pain intensity over time differs between somatosensory functioning evolution profiles in knee osteoarthritis (KOA) patients undergoing total knee arthroplasty (TKA). This …

  3. Open Access 01-12-2024 | Knee Osteoarthritis | OriginalPaper

    Contralateral knee osteoarthritis is a risk factor for ipsilateral knee osteoarthritis progressing: a case control study

    Knee osteoarthritis is a common type of arthritis characterized by cartilage loss, joint space narrowing, osteophyte formation, synovitis, and subchondral osteosclerosis, and it can cause knee joint stiffness, pain, and limited mobility. As KOA is …

  4. Open Access 17-04-2024 | Gene Therapy in Oncology | Online First

    Orthobiologics in knee osteoarthritis, dream or reality?

    Cartilage restoration or repair, also known as orthobiologic therapy, is indicated after the failure of conservative or supportive treatment. However, there is paucity in evidence supporting the efficacy of orthobiologic therapy. The blood-derived …

  5. 26-04-2024 | Knee Osteoarthritis | Online First

    Adjunct treatment with ozone to enhance therapy of knee osteoarthritis: preliminary results

    Knee osteoarthritis (knee OA), commonly known as gonarthrosis, is a chronic pathology involving knee at the joint level causing progressive pain, stiffness and difficulty in ambulation and leg movements. So far in situ infiltration therapies such …

  6. 10-05-2024 | Online First

    The impact of sericin on inflammation, oxidative stress, and lipid metabolism in female rats with experimental knee osteoarthritis

    Osteoarthritis (OA) is a chronic degenerative joint disease characterized by joint cartilage erosion, joint margin bone hypertrophy, subchondral sclerosis, varying degrees of inflammation, and biochemical and morphological changes in the synovial …

  7. Open Access 01-12-2024 | Knee Osteoarthritis | OriginalPaper

    The varying clinical effectiveness of single, three and five intraarticular injections of platelet-rich plasma in knee osteoarthritis

    Knee osteoarthritis (KOA) is a degenerative pathology distinguished primarily by knee pain and functional impairment, arising from progressive deterioration of the articular cartilage due to multiple influence of metabolic, biomechanical, and …

  8. Open Access 01-12-2024 | Osteoarthrosis | OriginalPaper

    Causal analysis of body composition measurements in osteoarthritis knee: a two-sample mendelian randomization study

    Osteoarthritis knee (KOA) is a chronic arthritic disease characterized by degenerative lesions and osteophytes in the knee cartilage [ 1 , 2 ]. Clinical manifestations include pain, restricted motion, joint deformity, and bone friction sounds [ 3 …4

  9. Open Access 01-12-2024 | Osteoarthrosis | OriginalPaper

    Effect of weight loss on knee joint synovitis over 48 months and mediation by subcutaneous fat around the knee: data from the Osteoarthritis Initiative

    Symptomatic knee osteoarthritis (OA) occurs in an estimated 14 million people in the US [ 1 ] and prevalence substantially increased over the last 20 years of the twentieth century, most likely independent of demographic changes in age and BMI [ 2 …

  10. Open Access 01-12-2024 | Knee Osteoarthritis | OriginalPaper

    Clinical phenotypes of comorbidities in end-stage knee osteoarthritis: a cluster analysis

    Knee osteoarthritis (KOA) is a chronic inflammatory and degenerative musculoskeletal disease whose incidence, prevalence, and years lived with disability are increasing every year, causing significant personal, economic, and social costs [ 1 , 2 ].

  11. 01-04-2024 | Osteoarthrosis | OriginalPaper

    Gardening/yardwork in people with knee osteoarthritis is not associated with symptom or structural progression over 48 months: data from the Osteoarthritis Initiative

    Osteoarthritis (OA) can lead to significant pain and loss of function. Approximately 80% of the US population over 65 years has radiographic evidence of OA, and 60% of this subset has symptoms [ 1 ].

  12. Open Access 01-12-2024 | Knee Osteoarthritis | OriginalPaper

    Demonstrating the effectiveness of intra-articular prolotherapy combined with peri-articular perineural injection in knee osteoarthritis: a randomized controlled trial

    Knee osteoarthritis (KOA) is one of the common degenerative disease in middle aged and elderly people, the incidence of KOA increased significantly with age [ 1 ]. KOA not only affects the life quality of patients, but also improves major economic …

  13. Open Access 18-04-2024 | Acupuncture | Online First

    Durable Effects of Acupuncture for Knee Osteoarthritis: A Systematic Review and Meta-analysis

    Knee osteoarthritis (KOA) is a degenerative joint disease that results from wear and tear and progressive loss of articular cartilage [ 1 ]. This condition causes chronic pain and locomotor disability, leading to significant impact on mobility …

  14. 24-01-2024 | Knee Osteoarthritis | ReviewPaper

    Clinical prediction models for knee pain in patients with knee osteoarthritis: a systematic review

    Knee osteoarthritis (OA) stands out as one of the most prevalent and debilitating chronic degenerative joint diseases [ 1 ]. Pain serves as the hallmark symptom of knee osteoarthritis [ 2 ] impacting 25–30% of individuals aged over 50, with a …

  15. 07-05-2024 | Respiratory Microbiota | Online First

    Effect of prebiotic fiber on physical function and gut microbiota in adults, mostly women, with knee osteoarthritis and obesity: a randomized controlled trial

    Knee osteoarthritis (OA) is a chronic debilitating joint condition where articular cartilage degenerates over time, resulting in joint swelling, pain, loss of function, and reduced independence [ 1 ]. Knee OA can lead to progressive disability …

  16. Open Access 01-12-2024 | Osteoarthrosis | OriginalPaper

    Effectiveness and safety of polyacrylamide hydrogel injection for knee osteoarthritis: results from a 12-month follow up of an open-label study

    Osteoarthritis (OA) is the most common form of arthritis, affecting 3.3–3.6% of the population globally [ 1 ]. OA is characterized by pathology involving the entire joint, including cartilage degradation, bone remodelling, osteophyte formation, and …

  17. Open Access 01-12-2024 | Knee Osteoarthritis | OriginalPaper

    Automatic measurement of lower limb alignment in portable devices based on deep learning for knee osteoarthritis

    Knee osteoarthritis (knee OA), can cause significant joint pain, decreased mobility, and even disability [ 1 ]. For patients in the end stage of the condition, Total Knee Arthroplasty (TKA) is a commonly used and highly effective therapy [ 2 ]. It …

  18. Open Access 01-12-2024 | Osteoarthrosis | OriginalPaper

    Phenotypes of osteoarthritis-related knee pain and their transition over time: data from the osteoarthritis initiative

    Knee osteoarthritis (OA) is a common joint disorder accompanied by chronic pain. Numerous studies have reported that knee OA accounts for lower extremity disability more than any other disease and causes a formidable societal burden [ 1 – 3 ].

  19. Open Access 01-12-2024 | Knee Osteoarthritis | OriginalPaper

    Factors associated with physical activity following total knee arthroplasty for knee osteoarthritis: a longitudinal study

    Osteoarthritis (OA) of the knee, the most commonly affected joint worldwide, is a leading cause of pain, disability, and socioeconomic loss [ 1 , 2 ]. Knee OA patients often limit their daily physical activity (PA) due to severe pain [ 3 ]. Total …

  20. Open Access 01-12-2024 | Knee Osteoarthritis | OriginalPaper

    Biomechanics of the lower limb in patients with mild knee osteoarthritis during the sit-to-stand task

    Knee osteoarthritis (KOA) is a prevalent and debilitating condition characterized by pain, stiffness, weakened quadriceps, instability, and impaired functionality [ 1 , 2 ]. It seriously affects patients’ quality of life, with approximately 650 …

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