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Reproductive Biology and Endocrinology

Issue 1/2021

Content (189 Articles)

Open Access Insulins Review

Caloric restriction in female reproduction: is it beneficial or detrimental?

Jiayi Sun, Xin Shen, Hui Liu, Siying Lu, Jing Peng, Haibin Kuang

Open Access Research

Regulation of ARHGAP19 in the endometrial epithelium: a possible role in the establishment of uterine receptivity

Jingjie Liang, Kui Li, Kaiyu Chen, Junyong Liang, Ti Qin, Jiayi He, Shuang Shi, Qiang Tan, Zhengguang Wang

Open Access Review

FSH regulates RA signaling to commit spermatogonia into differentiation pathway and meiosis

Maryam Khanehzad, Roya Abbaszadeh, Marzieh Holakuyee, Mohammad Hossein Modarressi, Seyed Mehdi Nourashrafeddin

Open Access Folic Acid Research

Association of three missense mutations in the homocysteine-related MTHFR and MTRR gene with risk of polycystic ovary syndrome in Southern Chinese women

Wanqin Feng, Yan Zhang, Yuan Pan, Yi Zhang, Minjuan Liu, Yuxin Huang, Yuanling Xiao, Wenyu Mo, Junjie Jiao, Xiaoyang Wang, Dan Tian, Lixia Yang, Ying Ma

Open Access Infertility Research

Hypoxia and its possible relationship with endometrial receptivity in adenomyosis: a preliminary study

Song Guo, Di Zhang, Xiaowei Lu, Qian Zhang, Ruihuan Gu, Binghui Sun, Yijuan Sun

Obesity Research

Leptin and inflammatory factors play a synergistic role in the regulation of reproduction in male mice through hypothalamic kisspeptin-mediated energy balance

Bo Chang, Chenglin Song, Haining Gao, Tie Ma, Tao Li, Qianhe Ma, Tingting Yao, Meng Wang, Jing Li, Xuejie Yi, Donghui Tang, Shicheng Cao

Open Access Infertility Research

Predictive value of live birth rate based on different intrauterine adhesion evaluation systems following TCRA

Mingzhu Cao, Yingying Pan, Qingyan Zhang, Danming You, Shuying Feng, Zhi Liu

Open Access Fertility Research

Pretreatment with melatonin improves ovarian tissue cryopreservation for transplantation

Marcos Eiji Shiroma, Luciana Lamarão Damous, Fernanda Pereira Cotrim, Cristiane Lima Roa, José Cipolla-Neto, Russel Joseph Reiter, Edmund Chada Baracat, José Maria Soares Jr

Open Access Mifepristone Research

Effect of Irisin on LIF and integrin αvβ3 in rats of implantation failure

Li Zhou, Chenggang Li, Xiangshu Liu, Tao Zhang

Open Access Miscarriage Research

Down‐regulation of the Sp1 transcription factor by an increase of microRNA-4497 in human placenta is associated with early recurrent miscarriage

Huaiyun Tang, Linqing Pan, Yun Xiong, Leilei Wang, Yugui Cui, Jiayin Liu, Lisha Tang

Open Access Fertility Research

Irisin deletion induces a decrease in growth and fertility in mice

Yunyao Luo, Xiaoyong Qiao, Yaxian Ma, Hongxia Deng, Charles C. Xu, Liangzhi Xu

Commentary on two recently published formal guidelines on management of “mosaic” embryos after preimplantation genetic testing for aneuploidy (PGT-A)

Norbert Gleicher, David H. Barad, Zion Ben-Rafael, Demian Glujovsky, Lyka Mochizuki, Deepak Modi, Maximillian Murtinger, Pasquale Patrizio, Raoul Orvieto, Shizuko Takahashi, Andrea Weghofer, Søren Ziebe

Open Access Endometriosis Research

Possible involvement of neuropeptide and neurotransmitter receptors in Adenomyosis

Xiaofang Xu, Xianjun Cai, Xishi Liu, Sun-Wei Guo

Open Access ICSI Research

Improved clinical outcomes after non-invasive oocyte selection and Day 3 eSET in ICSI patients

Inge Van Vaerenbergh, Tom Adriaenssens, Wim Coucke, Lisbet Van Landuyt, Greta Verheyen, Michaël De Brucker, Michel Camus, Peter Platteau, Michel De Vos, Elien Van Hecke, André Rosenthal, Johan Smitz

Open Access ICSI Research

Novel variants in DNAH9 lead to nonsyndromic severe asthenozoospermia

Dongdong Tang, Yanwei Sha, Yang Gao, Jingjing Zhang, Huiru Cheng, Junqiang Zhang, Xiaoqing Ni, Chao Wang, Chuan Xu, Hao Geng, Xiaojin He, Yunxia Cao

Open Access Fertility Research

Psychological experience and coping strategies of patients in the Northeast US delaying care for infertility during the COVID-19 pandemic

David B. Seifer, William D. Petok, Alisha Agrawal, Tanya L. Glenn, Arielle H. Bayer, Barry R. Witt, Blair D. Burgin, Harry J. Lieman

Identification of key pathways and genes in polycystic ovary syndrome via integrated bioinformatics analysis and prediction of small therapeutic molecules

Praveenkumar Devarbhavi, Lata Telang, Basavaraj Vastrad, Anandkumar Tengli, Chanabasayya Vastrad, Iranna Kotturshetti

Open Access Premature Birth Research

Whole blood RNA sequencing reveals a differential transcriptomic profile associated with cervical insufficiency: a pilot study

Ga-Hyun Son, So Yeon Choi, Yeon-Ji Ju, Keun-Young Lee, Jae Jun Lee, Ji-Eun Song, Youngmi Kim, Sung Taek Park

Open Access Orchitis Research

Silencing of MEG3 attenuated the role of lipopolysaccharides by modulating the miR-93-5p/PTEN pathway in Leydig cells

Xu Zhou, Jingliang He, Jinbo Chen, Yu Cui, Zhenyu Ou, Xiongbing Zu, Nenghui Liu

Open Access Research

Label-free proteomics uncovers SMC1A expression is Down-regulated in AUB-E

Yingxian Jia, Jie Luo, Yibing Lan, Chunming Li, Linjuan Ma, Xiaoming Zhu, Fei Ruan, Jianhong Zhou

Open Access Hirsutism Research

Characterization of polycystic ovary syndrome among Flo app users around the world

Tarun Jain, Olivia Negris, Dannielle Brown, Isabel Galic, Rodion Salimgaraev, Liudmila Zhaunova

Open Access Research

Effect of macrophages in semen on sperm quality

Gangxin Chen, Beihong Zheng

Open Access Research

Hsp90 modulates human sperm capacitation via the Erk1/2 and p38 MAPK signaling pathways

Peibei Sun, Yayan Wang, Tian Gao, Kun Li, Dongwang Zheng, Ajuan Liu, Ya Ni

Open Access Hysterectomy Research

The effect prophylactic internal iliac artery balloon occlusion in patients with placenta previa or placental accreta spectrum: a systematic review and meta‐analysis

Anisodowleh Nankali, Nader Salari, Mohsen Kazeminia, Masoud Mohammadi, Samira Rasoulinya, Melika Hosseinian-Far

Open Access Endometriosis Research

Expression of Talin-1 in endometriosis and its possible role in pathogenesis

Xian Tang, Qing Li, Lijie Li, Jianfa Jiang

Open Access Infertility Research

Controlled ovarian stimulation should not be preferred for male infertility treated with intrauterine insemination: a retrospective study

Yan Tang, Qian-Dong He, Ting-Ting Zhang, Jing-Jing Wang, Si-Chong Huang, Yun Ye

Open Access Ectopic Pregnancy Research

No significant long-term complications from inadvertent exposure to gonadotropin-releasing hormone agonist during early pregnancy in mothers and offspring: a retrospective analysis

Huan Wu, Xiaoyan Xu, Cong Ma, Yiran Zhou, Shanai Pei, Hao Geng, Ye He, Qianhua Xu, Yuping Xu, Xiaojin He, Ping Zhou, Zhaolian Wei, Xiaofeng Xu, Yunxia Cao

Open Access Contraception Research

A rodent model of human dose-equivalent progestin-only implantable contraception

Heather C. M. Allaway, Roger A. Pierson, Jesse Invik, Susan A. Bloomfield

Open Access Research

Aquaporin 3 promotes human extravillous trophoblast migration and invasion

Yingqi Nong, Shifen Li, Wenjuan Liu, Xiqian Zhang, Lin Fan, Ye Chen, Qianwen Huang, Qianyu Zhang, Fenghua Liu

Open Access In Vitro Fertilisation Review

Biosimilar recombinant follitropin alfa preparations versus the reference product (Gonal-F®) in couples undergoing assisted reproductive technology treatment: a systematic review and meta-analysis

Su Jen Chua, Ben W. Mol, Salvatore Longobardi, Raoul Orvieto, Christos A. Venetis, Monica Lispi, Ashleigh Storr, Thomas D’Hooghe

Open Access Infertility Research

Expression of tissue factor and tissue factor pathway inhibitors during ovulation in rats: a relevance to the ovarian hyperstimulation syndrome

You Jee Jang, Hee Kyung Kim, Bum Chae Choi, Sang Jin Song, Jae Il Park, Sang Young Chun, Moon Kyoung Cho

Open Access Artificial Intelligence Research

Individualized embryo selection strategy developed by stacking machine learning model for better in vitro fertilization outcomes: an application study

Qingsong Xi, Qiyu Yang, Meng Wang, Bo Huang, Bo Zhang, Zhou Li, Shuai Liu, Liu Yang, Lixia Zhu, Lei Jin

Open Access Research

Effect of resveratrol on mouse ovarian vitrification and transplantation

Dalin Wang, Menghui Geng, Dongying Gan, Gege Han, Gao Gao, Aying Xing, Yugui Cui, Yanqiu Hu

Open Access Hypertension Research

Serum complement proteomics reveal biomarkers for hypertension disorder of pregnancy and the potential role of Clusterin

Shanshui Zeng, Mengru Han, Min Jiang, Fei Liu, Yanwei Hu, Yan Long, Chunyan Zhu, Fangling Zeng, Qiangsheng Gan, Weitao Ye, Wenjin Fu, Hongling Yang

Open Access Research

WAPL orchestrates porcine oocyte meiotic progression via control of spindle assembly checkpoint activity

Changyin Zhou, Yilong Miao, Xue Zhang, Bo Xiong

Successful birth after preimplantation genetic testing for a couple with two different reciprocal translocations and review of the literature

Dun Liu, Chuangqi Chen, Xiqian Zhang, Mei Dong, Tianwen He, Yunqiao Dong, Jian Lu, Lihua Yu, Chuanchun Yang, Fenghua Liu

Open Access Fertility Research

The effect of Myo-inositol on fertility rates in poor ovarian responder in women undergoing assisted reproductive technique: a randomized clinical trial

Sahar Mohammadi, Fatemeh Eini, Fatemeh Bazarganipour, Seyed Abdolvahab Taghavi, Maryam Azizi Kutenaee

Open Access Correction

Correction to: Subcellular localization of L-selectin ligand in the endometrium implies a novel function for pinopodes in endometrial receptivity

Reza Nejatbakhsh, Maryam Kabir-Salmani, Evdokia Dimitriadis, Ahmad Hosseini, Robabeh Taheripanah, Yousef Sadeghi, Yoshihiro Akimoto, Mitsutoshi Iwashita

Open Access Cytostatic Therapy Research

Quercetin prevents primordial follicle loss via suppression of PI3K/Akt/Foxo3a pathway activation in cyclophosphamide-treated mice

Jianghui Li, Hui Long, Yanyan Cong, Hongyuan Gao, Qifeng Lyu, Sha Yu, Yanping Kuang

Open Access Research

Fluorochloridone induces autophagy in TM4 Sertoli cells: involvement of ROS-mediated AKT-mTOR signaling pathway

Zhijing Ni, Weiqi Sun, Rui Li, Mingjun Yang, Fen Zhang, Xiuli Chang, Weihua Li, Zhijun Zhou

Open Access Polycystic Ovary Syndrome Review

Uric acid participating in female reproductive disorders: a review

Junhao Hu, Wenyi Xu, Haiyan Yang, Liangshan Mu

Open Access Infertility Correction

Correction to: Psychological experience and coping strategies of patients in the Northeast US delaying care for infertility during the COVID-19 pandemic

David B. Seifer, William D. Petok, Alisha Agrawal, Tanya L. Glenn, Arielle H. Bayer, Barry R. Witt, Blair D. Burgin, Harry J. Lieman

Open Access Uterine Myoma Research

Evaluation of vitamin D receptor expression in uterine leiomyoma and nonneoplastic myometrial tissue: a cross‐sectional controlled study

Maria Simone Oliveira Lima, Benedito Borges da Silva, Menandro Lima de Medeiros, Alesse Ribeiro dos Santos, Emerson Davi do Nascimento Brazil, Walberto Monteiro Neiva Eulálio Filho, Jerusia Oliveira Ibiapina, Antônio Gilberto Albuquerque Brito, Pedro Vitor Lopes Costa

Dose adjustment of follicle-stimulating hormone (FSH) during ovarian stimulation as part of medically-assisted reproduction in clinical studies: a systematic review covering 10 years (2007–2017)

Human Fatemi, Wilma Bilger, Deborah Denis, Georg Griesinger, Antonio La Marca, Salvatore Longobardi, Mary Mahony, Xiaoyan Yin, Thomas D’Hooghe

Open Access Infertility Research

Does mRNA SARS-CoV-2 vaccine influence patients' performance during IVF-ET cycle?

Raoul Orvieto, Meirav Noach-Hirsh, Aliza Segev-Zahav, Jigal Haas, Ravit Nahum, Adva Aizer

Open Access Hypertension Research

Proteinuria may be an indicator of adverse pregnancy outcomes in patients with preeclampsia: a retrospective study

Tingting Lei, Ting Qiu, Wanyu Liao, Kangjie Li, Xinyue Lai, Hongbo Huang, Rui Yuan, Ling Chen

Open Access Polycystic Ovary Syndrome Research

Extracellular microRNAs: key players to explore the outcomes of in vitro fertilization

Haroon Latif Khan, Shahzad Bhatti, Sana Abbas, Celal Kaloglu, Ahmed M. Isa, Hooria Younas, Rachel Ziders, Yousaf Latif Khan, Zahira Hassan, Bilgün Oztürk Turhan, Aysegul Yildiz, Hikmet Hakan Aydin, Ender Yalcinkaya Kalyan

Open Access Infertility Research

Epithelial apical glycosylation changes associated with thin endometrium in women with infertility - a pilot observational study

Marina M. Ziganshina, Nataliya V. Dolgushina, Galina V. Kulikova, Nafisa M. Fayzullina, Ekaterina L. Yarotskaya, Nailia R. Khasbiullina, Nigora F. Abdurakhmanova, Aleksandra V. Asaturova, Alexander I. Shchegolev, Alina A. Dovgan, Gennady T. Sukhikh

Age-specific cut-off levels of anti-Müllerian hormone can be used as diagnostic markers for polycystic ovary syndrome

Fahimeh Ramezani Tehrani, Maryam Rahmati, Fatemeh Mahboobifard, Faezeh Firouzi, Nazanin Hashemi, Fereidoun Azizi

Open Access Polycystic Ovary Syndrome Research

Metformin reduces androgen receptor and upregulates homeobox A10 expression in uterine endometrium in women with polycystic ovary syndrome

Miki Ohara, Hiromi Yoshida-Komiya, Miho Ono-Okutsu, Akiko Yamaguchi-Ito, Toshifumi Takahashi, Keiya Fujimori

Open Access Ectopic Pregnancy Research

Ectopic pregnancy: a single-center experience over ten years

Ammar Al Naimi, Pablo Moore, Dörthe Brüggmann, Lisa Krysa, Frank Louwen, Franz Bahlmann

Open Access Fertility Research

The effect of lysophosphatidic acid-supplemented culture medium on human immature oocytes matured in vitro

Qigui Xie, Yaxin Xing, Jianhong Zhou, Ling Wang, Jie Wu, Ri-Cheng Chian

Open Access Infertility Research

Effects of localisation of uterine adenomyosis on outcome of in vitro fertilisation/intracytoplasmic sperm injection fresh and frozen-thawed embryo transfer cycles: a multicentre retrospective cohort study

Takuya Iwasawa, Toshifumi Takahashi, Eri Maeda, Koichi Ishiyama, Satoshi Takahashi, Ryota Suganuma, Koki Matsuo, Masahito Tachibana, Rie Fukuhara, Hiromitsu Shirasawa, Wataru Sato, Yukiyo Kumazawa, Yukihiro Terada

Open Access Research

MicroRNA-30a-5p promotes differentiation in neonatal mouse spermatogonial stem cells (SSCs)

Maryam Khanehzad, Seyed Mehdi Nourashrafeddin, Farid Abolhassani, Shokoofeh Kazemzadeh, Soheila Madadi, Elham Shiri, Parastoo Khanlari, Zahra Khosravizadeh, Azim Hedayatpour

Open Access Shock Research

HSF1 promotes endometriosis development and glycolysis by up-regulating PFKFB3 expression

Yixin Wang, Jing Xiu, Tingting Yang, Chune Ren, Zhenhai Yu

Open Access Bleaching Short communication

H3.3 kinetics predicts chromatin compaction status of parental genomes in early embryos

Shi-meng Guo, Xing-ping Liu, Li-quan Zhou

Open Access Miscarriage Research

Downregulation of decidual SKP2 is associated with human recurrent miscarriage

Shijian Lv, Mei Liu, Lizhen Xu, Cong Zhang

Open Access Androgens Review

Recombinant human luteinizing hormone co-treatment in ovarian stimulation for assisted reproductive technology in women of advanced reproductive age: a systematic review and meta-analysis of randomized controlled trials

Alessandro Conforti, Sandro C. Esteves, Peter Humaidan, Salvatore Longobardi, Thomas D’Hooghe, Raoul Orvieto, Alberto Vaiarelli, Danilo Cimadomo, Laura Rienzi, Filippo Maria Ubaldi, Fulvio Zullo, Carlo Alviggi

Open Access Chlamydia Trachomatis Research

Sexually transmitted infections and semen quality from subfertile men with and without leukocytospermia

Shun Bai, Yuan Li, Yangyang Wan, Tonghang Guo, Qi Jin, Ran Liu, Wenjuan Tang, Meiying Sang, Yuanyuan Tao, Baoguo Xie, Yun Zhao, Wei Li, Xiangdong Xu, Qiuling Yue, Xuechun Hu, Bo Xu

Open Access Miscarriage Research

Endometrial thickness following early miscarriage in IVF patients – is there a preferred management approach?

Gilad Karavani, Heli Alexandroni, Daniel Sheinin, Uri P. Dior, Alex Simon, Assaf Ben-Meir, Benjamin Reubinoff

Open Access Androgens Research

Prolactin promotes a partial recovery from the atrophy of both male and female gerbil prostates caused by castration

Marianna Zanatelli, Simone Jacovaci Colleta, Luiz Henrique Alves Guerra, Fernanda Cristina Alcântara Santos, Rejane Maira Góes, Patricia Simone Leite Vilamaior, Sebastião Roberto Taboga

Open Access Fertility Research

OTOGL, a gelforming mucin protein, is nonessential for male germ cell development and spermatogenesis in mice

Zhiming Li, Yan Zhang, Xinzong Zhang, Congcong Cao, Xiaomin Luo, Yaoting Gui, Yunge Tang, Shuiqiao Yuan

Open Access Research

Preimplantation factor modulates trophoblastic invasion throughout the decidualization of human endometrial stromal cells

Esther Dos Santos, Hadia Moindjie, Valérie Sérazin, Lucie Arnould, Yoann Rodriguez, Khadija Fathallah, Eytan R. Barnea, François Vialard, Marie-Noëlle Dieudonné

Open Access GnRH Agonists Research

Down-regulation of S100P induces apoptosis in endometrial epithelial cell during GnRH antagonist protocol

Dan Zhang, Mi Han, Mingjuan Zhou, Mengyu Liu, Yan Li, Bufang Xu, Aijun Zhang

Open Access Pre-Eclampsia Review

Roles of noncoding RNAs in preeclampsia

Ningxia Sun, Shiting Qin, Lu Zhang, Shiguo Liu

Open Access Ectopic Pregnancy Research

Abnormally increased DNA methylation in chorionic tissue might play an important role in development of ectopic pregnancy

Wen Cai, Liu Yang, Ruiqing Zhang, Yixia Yang, Shuangdi Li, Jiarong Zhang

Fertility Research

Evaluation of testicular glycogen storage, FGF21 and LDH expression and physiological parameters of sperm in hyperglycemic rats treated with hydroalcoholic extract of Securigera Securidaca seeds, and Glibenclamide

Mohammad Babaei, Shahin Alizadeh-Fanalou, Alireza Nourian, Sahar Yarahmadi, Navid Farahmandian, Mohsen Nabi-Afjadi, Iraj Alipourfard, Elham Bahreini

Open Access Research

High-coverage targeted lipidomics revealed dramatic lipid compositional changes in asthenozoospermic spermatozoa and inverse correlation of ganglioside GM3 with sperm motility

Shuqiang Chen, Ming Wang, Li Li, Jun Wang, Xuhui Ma, Hengde Zhang, Yang Cai, Bin Kang, Jianlei Huang, Bo Li

Open Access Epigenetics Research

5-aza-2′-deoxycitidine inhibits cell proliferation, extracellular matrix formation and Wnt/β-catenin pathway in human uterine leiomyomas

María Cristina Carbajo-García, Ana Corachán, Marina Segura-Benitez, Javier Monleón, Julia Escrig, Amparo Faus, Antonio Pellicer, Irene Cervelló, Hortensia Ferrero

Open Access Research

Characterization of the effects of heat stress on autophagy induction in the pig oocyte

Benjamin J. Hale, Yunsheng Li, Malavika K. Adur, Aileen F. Keating, Lance H. Baumgard, Jason W. Ross

Open Access Research

Construction of lncRNA-related competing endogenous RNA network and identification of hub genes in recurrent implantation failure

Jialyu Huang, Ning Song, Leizhen Xia, Lifeng Tian, Jun Tan, Qianqian Chen, Jing Zhu, Qiongfang Wu

Open Access Research

MiR-191-5p is upregulated in culture media of implanted human embryo on day fifth of development

Ricardo Josué Acuña-González, Mercedes Olvera-Valencia, Jorge Skiold López-Canales, Jair Lozano-Cuenca, Mauricio Osorio-Caballero, Héctor Flores-Herrera

Open Access Research

Time associations between U.S. birth rates and add-Ons to IVF practice between 2005–2016

Norbert Gleicher, Lyka Mochizuki, David H. Barad

Open Access Endometriosis Research

Overexpressed MPS-1 contributes to endometrioma development through the NF-κB signaling pathway

Yang Liu, Junyan Ma, Liqi Zhang, Jun Lin, Xiaohua Liu

Open Access Research

Tumor susceptibility gene 101 is required for the maintenance of uterine epithelial cells during embryo implantation

Hyunji Byun, Sojung Kwon, Kay-Uwe Wagner, Hyejin Shin, Hyunjung Jade Lim

Open Access Mifepristone Research

Mifepristone inhibited the expression of B7-H2, B7-H3, B7-H4 and PD-L2 in adenomyosis

Xiaoyan Qin, Wenjing Sun, Chong Wang, Mingjiang Li, Xingbo Zhao, Changzhong Li, Hui Zhang

Open Access Research

Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication

Kasun Godakumara, James Ord, Freddy Lättekivi, Keerthie Dissanayake, Janeli Viil, Nageswara Rao Boggavarapu, Omid R Faridani, Kersti Jääger, Agne Velthut-Meikas, Ülle Jaakma, Andres Salumets, Alireza Fazeli

Open Access Infertility Research

More blastocysts are produced from fewer oocytes in ICSI  compared to IVF – results from a sibling oocytes study and definition of a new key performance indicator

Sandrine Chamayou, Carmen Ragolia, Carmelita Alecci, Giorgia Storaci, Simona Romano, Roberta Sapienza, Elena Maglia, Annalisa Liprino, Clementina Cardea, Michele Fichera, Antonino Guglielmino

Open Access Publisher Correction

Correction to: Status of racial disparities between black and white women undergoing assisted reproductive technology in the US

David B. Seifer, Burcin Simsek, Ethan Wantman, Alexander M. Kotlyar

Open Access Research

BPA and BPS affect the expression of anti-Mullerian hormone (AMH) and its receptor during bovine oocyte maturation and early embryo development

Angela Christina Saleh, Reem Sabry, Gabriela Fabiana Mastromonaco, Laura Alessandra Favetta

Open Access Infertility Research

Decreased angiotensin receptor 1 expression in ± AT1 Knockout mice testis results in male infertility and GnRH reduction

Fangfang Zhao, Yun Zou, Hui Li, Yaheng Zhang, Xuele Liu, Xuehao Zhao, Xinyi Wu, Wenyi Fei, Ziling Xu, Xuejun Yang

Open Access ICSI Review

Should rescue ICSI be re-evaluated considering the deferred transfer of cryopreserved embryos in in-vitro fertilization cycles? A systematic review and meta-analysis

Alessio Paffoni, Marco Reschini, Valerio Pisaturo, Cristina Guarneri, Simone Palini, Paola Viganò

Open Access Research

Circular RNA hsa_circ_0081343 promotes trophoblast cell migration and invasion and inhibits trophoblast apoptosis by regulating miR-210-5p/DLX3 axis

Hui Wang, Caiqun Luo, Xiaoxia Wu, Jianming Zhang, Zhiyong Xu, Yang Liu, Bohong Li, Jing Li, Jiansheng Xie

Open Access COVID-19 Research

Maternal and infant outcomes during the COVID-19 pandemic: a retrospective study in Guangzhou, China

Jingyun Wang, Yun Wang, Mei-yao He, Yi-xiao Li, Xin Cheng, Xuesong Yang, Rui-man Li, Guang Wang

Open Access Infertility Research

Novel variants in helicase for meiosis 1 lead to male infertility due to non-obstructive azoospermia

Dongdong Tang, Mingrong Lv, Yang Gao, Huiru Cheng, Kuokuo Li, Chuan Xu, Hao Geng, Guanjian Li, Qunshan Shen, Chao Wang, Xiaojin He, Yunxia Cao

Investigation of optimal gestational weight gain based on the occurrence of adverse pregnancy outcomes for Chinese women: a prospective cohort study

Yin Sun, Zhongzhou Shen, Yongle Zhan, Yawen Wang, Shuai Ma, Suhan Zhang, Juntao Liu, Sansan Wu, Yahui Feng, Yunli Chen, Shuya Cai, Yingjie Shi, Liangkun Ma, Yu Jiang

Infertility Research

Immediate versus delayed frozen embryo transfer in women following a failed IVF-ET attempt: a multicenter randomized controlled trial

Jing-Yan Song, Feng-Yi Dong, Li Li, Xing-Xing Zhang, Ai-Juan Wang, Yi Zhang, Dan-Dan Gao, Ji-Mei Xiao, Zhen-Gao Sun

Open Access Endometriosis Research

HOX cluster and their cofactors showed an altered expression pattern in eutopic and ectopic endometriosis tissues

Fereshteh Esfandiari, Fereshteh Chitsazian, Masoumeh Golestan Jahromi, Raha Favaedi, Masood Bazrgar, Reza Aflatoonian, Parvaneh Afsharian, Abbas Aflatoonian, Maryam Shahhoseini

Fertility Research

Single-cell transcriptome and cell-specific network analysis reveal the reparative effect of neurotrophin-4 in preantral follicles grown in vitro

Yingchun Guo, Peigen Chen, Tingting Li, Lei Jia, Yi Zhou, Jiana Huang, Xiaoyan Liang, Chuanchuan Zhou, Cong Fang

Open Access Correction

Correction to: OTOGL, a gelforming mucin protein, is nonessential for male germ cell development and spermatogenesis in mice

Zhiming Li, Yan Zhang, Xinzong Zhang, Congcong Cao, Xiaomin Luo, Yaoting Gui, Yunge Tang, Shuiqiao Yuan

Open Access Infertility Research

Expression and significance of miR-30d-5p and SOCS1 in patients with recurrent implantation failure during implantation window

Yuhao Zhao, Dongmei He, Hong Zeng, Jiefeng Luo, Shuang Yang, Jingjing Chen, Raed K. Abdullah, Nenghui Liu

Open Access Estradiol Research

TRIB3 regulates FSHR expression in human granulosa cells under high levels of free fatty acids

Nan Wang, Chenchen Si, Lan Xia, Xian Wu, Sheng Zhao, Huihui Xu, Zhide Ding, Zhihong Niu

Open Access Short communication

Follistatin supplementation induces changes in CDX2 CpG methylation and improves in vitro development of bovine SCNT preimplantation embryos

Mohamed Ashry, Chunyan Yang, Sandeep K. Rajput, Joseph K. Folger, Jason G. Knott, George W. Smith

Open Access Multiple Pregnancy Research

Sequential cleavage and blastocyst embryo transfer and IVF outcomes: a systematic review

Jianeng Zhang, Chong Wang, Huanhuan Zhang, Yan Zhou

Open Access Progesterone Research

UHPLC-MS-MS analysis of oxylipins metabolomics components of follicular fluid in infertile individuals with diminished ovarian reserve

Chengcheng Liang, Xiaole Zhang, Cong Qi, Hui Hu, Qinhua Zhang, Xiuxian Zhu, Yonglun Fu

Open Access Short communication

The Spin1 interactor, Spindoc, is dispensable for meiotic division, but essential for haploid spermatid development in mice

Xue Jiang, Xiaoli Zhu, Yu Cheng, Muhammad Azhar, Xuemei Xing, Wenqing Li, Yuzhu Cao, Qinghua Shi, Jianqiang Bao

ICSI Research

Higher preconceptional maternal body mass index is associated with faster early preimplantation embryonic development: the Rotterdam periconception cohort

Linette van Duijn, Melek Rousian, Jeffrey Hoek, Sten P. Willemsen, Eva S. van Marion, Joop S. E. Laven, Esther B. Baart, Régine P. M. Steegers-Theunissen

Open Access Insulins Review

A comprehensive insight into effects of green tea extract in polycystic ovary syndrome: a systematic review

Vahid Maleki, Ehsaneh Taheri, Parisa Varshosaz, Fatemeh Pourteymour Fard Tabrizi, Jalal Moludi, Hamed Jafari-Vayghan, Mahdi Shadnoush, Seyed Hossein Yahyazadeh Jabbari, Mehri Seifoleslami, Mohammad Alizadeh

Open Access Fertility Research

Obesity induces morphological and functional changes in female reproductive system through increases in NF-κB and MAPK signaling in mice

Xiuxiu Gao, Yangyang Li, Zhuoyao Ma, Jia Jing, Zhengqing Zhang, Yue Liu, Zhide Ding

Open Access Infertility Research

Trapa bispinosa Roxb. extract lowers advanced glycation end-products and increases live births in older patients with assisted reproductive technology: a randomized controlled trial

Masao Jinno, Ryoji Nagai, Masayoshi Takeuchi, Aiko Watanabe, Koji Teruya, Hikari Sugawa, Naohisa Hatakeyama, Yuichi Jinno

Open Access Review

miRNAs in decidual NK cells: regulators worthy of attention during pregnancy

Liman Li, Ting Feng, Weijie Zhou, Yuan Liu, Hong Li

Open Access Fertility Research

The effect of short term exposure to outdoor air pollution on fertility

Mireia González-Comadran, Bénédicte Jacquemin, Marta Cirach, Rafael Lafuente, Thomas Cole-Hunter, Mark Nieuwenhuijsen, Mario Brassesco, Buenaventura Coroleu, Miguel Angel Checa

Open Access Breast Cancer Research

Preimplantation genetic testing for BRCA gene mutation carriers: a cost effectiveness analysis

Nadav Michaan, Moshe Leshno, Yoni Cohen, Tamar Safra, Shira Peleg-Hasson, Ido Laskov, Dan Grisaru

Open Access Research

Alterations of miR-16, miR-let-7a and their target genes expression in human blastocysts following vitrification and re-vitrification

Maryam Daneshvar, Mansoureh Movahedin, Mohammad Salehi, Mehrdad Noruzinia

Open Access Fertility Research

Impact of human papillomavirus infection on semen parameters and reproductive outcomes

Hana Jaworek, Vladimira Koudelakova, Ivana Oborna, Blazena Zborilova, Jana Brezinova, Dagmar Ruzickova, Jana Vrbkova, Pavla Kourilova, Marian Hajduch

Infertility Research

Impact of infertility duration on female sexual health

Meng Dong, Xiaoyan Xu, Yining Li, Yixian Wang, Zhuo Jin, Jichun Tan

Open Access ICSI Research

Laser-assisted selection of immotile spermatozoa has no effect on obstetric and neonatal outcomes of TESA-ICSI pregnancies

Huanhua Chen, Caizhu Wang, Hong Zhou, Jinhui Shu, Xianyou Gan, Kongrong Xu, Zhulian Wu, Xihe Deng, Guiting Huang, Ruoyun Lin

Open Access ICSI Research

Impact of endometriosis on oocyte morphology in IVF-ICSI: retrospective study of a cohort of more than 6000 mature oocytes

Camille Robin, Audrey Uk, Christine Decanter, Hélène Behal, Pierre Collinet, Chrystèle Rubod, Anne-Laure Barbotin, Geoffroy Robin

Open Access Endometriosis Research

WEE1 promotes endometriosis via the Wnt/β-catenin signaling pathway

Liya Shi, Xue Xue, Hui Tian, Hongjuan Ye, Hui Wang, Rongxiang Wang, Yu Liu, Caixia Zhang, Qiuju Chen, Lihua Sun

Research

Effects of Aurora kinase A on mouse decidualization via Stat3-plk1-cdk1 pathway

Peng-Chao Wang, Si-Ting Chen, Zeng-Ming Yang

Open Access Ultrasound Research

Corpus luteum number and the maternal renin-angiotensin-aldosterone system as determinants of utero-placental (vascular) development: the Rotterdam Periconceptional Cohort

Rosalieke E. Wiegel, Maud J. H. Karsten, Igna F. Reijnders, Lenie van Rossem, Sten P. Willemsen, Annemarie G. M. G. J. Mulders, Anton H. J. Koning, Eric A. P. Steegers, A. H. Jan Danser, Régine P. M. Steegers-Theunissen

Open Access Polycystic Ovary Syndrome Research

Circ_0043532 regulates miR-182/SGK3 axis to promote granulosa cell progression in polycystic ovary syndrome

Lishuang Xu, Fang Xiong, Yinyang Bai, Juxia Xiao, Yun Zhang, Jie Chen, Qiuping Li

Open Access Metformin Research

Icariin improves testicular dysfunction via enhancing proliferation and inhibiting mitochondria-dependent apoptosis pathway in high-fat diet and streptozotocin-induced diabetic rats

Weiguo He, Huiqing Liu, Linlin Hu, Yaohui Wang, Lane Huang, Aihong Liang, Xuan Wang, Qing Zhang, Yi Chen, Yi Cao, Suyun Li, Junli Wang, Xiaocan Lei

Open Access ICSI Research

The altered immunological status of children conceived by assisted reproductive technology

Xin Xu, Han Wu, Yuehong Bian, Linlin Cui, Yuanyuan Man, Zhao Wang, Xin Zhang, Changming Zhang, Ling Geng

Open Access Infertility Research

Differences in ICSI utilization rates among states with insurance mandates for ART coverage

Pavel Zagadailov, Kyung S. Cho, David B. Seifer

Open Access Polycystic Ovary Syndrome Research

Involvement of impaired CD8+ mucosal-associated invariant T cells and myeloid-derived suppressor cells in polycystic ovary syndrome

Mengting Zhu, Yuping Xu, Caihua Li, Zhimin Lu, Kaihuan Bi, Kangxia Wang, Peipei Guo, Huanhuan Jiang, Yunxia Cao

Open Access Ovarian Cancer Research

CircCRIM1 promotes ovarian cancer progression by working as ceRNAs of CRIM1 and targeting miR-383-5p/ZEB2 axis

Yuping Du, Xin Liu, Song Zhang, Shuo Chen, Xue Guan, Qianhui Li, Xi Chen, Yang Zhao

Open Access Ovarian Cancer Review

Circulating tumor DNA: a noninvasive biomarker for tracking ovarian cancer

Fang Yang, Jun Tang, Zihao Zhao, Chunling Zhao, Yuancai Xiang

Open Access Cystectomy Research

Impact of perioperative use of GnRH agonist or dienogest on ovarian reserve after cystectomy for endometriomas: a randomized controlled trial

Ayako Muraoka, Satoko Osuka, Atsushi Yabuki, Bayasula, Masato Yoshihara, Hideaki Tanaka, Reina Sonehara, Natsuki Miyake, Mayuko Murakami, Sayako Yoshita, Natsuki Nakanishi, Tomoko Nakamura, Maki Goto, Akira Iwase, Hiroaki Kajiyama

Open Access Research

Pak2 reduction induces a failure of early embryonic development in mice

Juan Zeng, Nengqing Liu, Yinghong Yang, Yi Cheng, Yuanshuai Li, Xiaoxia Guo, Qian Luo, Lifen Zhu, Hongmei Guan, Bing Song, Xiaofang Sun

Open Access ICSI Research

Analysis of maturation dynamics and developmental competence of in vitro matured oocytes under time-lapse monitoring

Qiyu Yang, Lixia Zhu, Meng Wang, Bo Huang, Zhou Li, Juan Hu, Qingsong Xi, Jing Liu, Lei Jin

Open Access Miscarriage Research

Association between clinical and IVF laboratory parameters and miscarriage after single euploid embryo transfers

María del Carmen Nogales, María Cruz, Silvia de Frutos, Eva María Martínez, María Gaytán, Marta Ariza, Fernando Bronet, Juan A. Garcia-Velasco

Open Access Research

Increased METTL3-mediated m6A methylation inhibits embryo implantation by repressing HOXA10 expression in recurrent implantation failure

Pingping Xue, Wenbo Zhou, Wenqiang Fan, Jianya Jiang, Chengcai Kong, Wei Zhou, Jianmei Zhou, Xiaoyang Huang, Haiyan Yang, Qian Han, Bin Zhang, Lingyun Xu, Bin Yu, Li Chen

Open Access Research

The inhibitory effect of AMP-activated protein kinase (AMPK) on chemokine and prostaglandin production in human endometrial stromal cells

Yasushi Kawano, Hatsumi Sato, Kaori Goto, Masakazu Nishida, Kaei Nasu

Open Access Atorvastatin Research

The effects of statins on hyperandrogenism in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials

Jianguo Chen, Chaoran Huang, Tongtong Zhang, Wuqing Gong, Xiaofeng Deng, Hua Liu, Jinbo Liu, Yuanbiao Guo