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Reproductive Biology and Endocrinology

Issue 1/2024

Content (159 Articles)

The impact of COVID-19 on the mental and sexual health of patients with infertility: a prospective before-and-after study

Jing Qi, Meng Sun, Xingchen Yue, Xintong Hong, Meng Dong, Jichun Tan

Elevated first-trimester neutrophil elastase and proteinase 3 increase the risk of gestational diabetes mellitus and adverse fetal outcomes

Lihong Wang, Zhoujunhao Zhou, Xinming Xu, Yue Li, Rui Zhang, Zhiyan Yu, Xinmei Huang, Shufei Zang, Tiange Sun

Expression of NELL2/NICOL-ROS1 lumicrine signaling-related molecules in the human male reproductive tract

  • Open Access
  • Research

Daiji Kiyozumi

The association between serum testosterone level and congestive heart failure in US male adults: data from National Health and Nutrition Examination Survey (NHANES) 2011–2016

Xiangpeng Zhan, Yang Liu, Tao Chen, Hao Wan, Situ Xiong, Sheng Li, Xinxi Deng, Luyao Chen, Bin Fu

NET1 is a critical regulator of spindle assembly and actin dynamics in mouse oocytes

  • Open Access
  • Research

Shiwei Wang, Xuan Wu, Mengmeng Zhang, Siyu Chang, Yajun Guo, Shuang Song, Shizhen Dai, Keliang Wu, Shenming Zeng

Long pentraxin 3 and vitamin D receptor mRNA expression pattern of cumulus granulosa cells isolated from PCOS oocytes at different stages of nuclear maturation

Aynur Ersahin, Onder Celik, Nur D. Gungor, Nilufer Celik, Sureyya Melil, Meltem Yardim, Semih Dalkilic, Cenk Ersahin, Ece Dogukargin, Sudenaz Celik, Ramazan F. Akkoc

Follitropin delta combined with menotropin in patients at risk for poor ovarian response during in vitro fertilization cycles: a prospective controlled clinical study

Oscar Barbosa Duarte-Filho, Eduardo Hideki Miyadahira, Larissa Matsumoto, Lucas Yugo Shiguehara Yamakami, Renato Bussadori Tomioka, Sergio Podgaec

Outcomes of BRCA pre-implantation genetic testing according to the parental mutation origin: a cohort study

Ilana Weizel, Tal Shavit, Yulia Shuli, Chana Adler Lazarovich, Rivka Halevi, Tal Ben Ari, Shira Yaacobi-Artzi, Yaakov Bentov, Baruch Feldman, Anat Hershko Klement

Diagnosis and management of infertility: NICE-adapted guidelines from the Italian Society of Human Reproduction

Stefano Palomba, Paola Viganò, Sandrine Chamayou, Zaira Donarelli, Maria Paola Costantini, Roberto Marci, Paola Piomboni, Egidio Fino, Luigi Montano, Antonino Guglielmino, Edgardo Somigliana, Nicola Arrighi, Anna Biallo, Luca Boeri, Antonella Cinotti, Elisabetta Coccia, Giacomo D’Amico, Cinzia Di Matteo, Vincenzo Favilla, Guglielmino Antonino, Maria Giulia Minasi, Veronica Ricciuto, Marco Sbracia, Francesca Spinella, Maria Vitale, Giulia Eleonora Carmela Zinno

Transcriptome analysis of adenomyosis eutopic endometrium reveals molecular mechanisms involved in adenomyosis-related implantation failure and pregnancy disorders

Elena Juárez-Barber, Ana Corachán, María Cristina Carbajo-García, Amparo Faus, Carmen Vidal, Juan Giles, Antonio Pellicer, Irene Cervelló, Hortensia Ferrero

Intra-ovarian inflammatory states and their associations with embryo quality in normal-BMI PCOS patients undergoing IVF treatment

Jie Shang, Siyu Wang, Aiyuan Wang, Fang Li, Jing Zhang, Jin Wang, Rui Lv, Haixia Chen, Xiaohuan Mu, Kai Zhang, Xiaohong Bai, Ye Tian

Associations between the artificial intelligence scoring system and live birth outcomes in preimplantation genetic testing for aneuploidy cycles

Chun-I Lee, Chun-Chia Huang, Tsung-Hsien Lee, Hsiu-Hui Chen, En-Hui Cheng, Pin-Yao Lin, Tzu-Ning Yu, Chung-I Chen, Chien-Hong Chen, Maw-Sheng Lee

Alterations in gut and genital microbiota associated with gynecological diseases: a systematic review and meta-analysis

Ziwei Zhou, Yifei Feng, Lishan Xie, Song Ma, Zhaoxia Cai, Ying Ma

Serum erythropoietin level is increased during stimulation for IVF but not in OHSS

Merituuli Rekola, Kati Korhonen, Leila Unkila-Kallio, Henrik Alfthan, Vedran Stefanovic, Aila Tiitinen, Tomi S. Mikkola, Hanna Savolainen-Peltonen

Inhibition of mitochondrial cyclophilin D, a downstream target of glycogen synthase kinase 3α, improves sperm motility

  • Open Access
  • Research

Seung Hyun Park, Myung Chan Gye

MiR-124-3p negatively impacts embryo implantation via suppressing uterine receptivity formation and embryo development

  • Open Access
  • Research

Kezhen Yao, Quanmin Kang, Kai Chen, Biwei Shi, Xiaofen Jin

miR-6881-3p contributes to diminished ovarian reserve by regulating granulosa cell apoptosis by targeting SMAD4

  • Open Access
  • Research

Wenhan Ju, Shuai Zhao, Haicui Wu, Yi Yu, Yuan Li, Danqi Liu, Fang Lian, Shan Xiang

Outpatient hysteroscopy impact on subsequent assisted reproductive technology: a systematic review and meta-analysis in patients with normal transvaginal sonography or hysterosalpingography images

Jung-Hsiu Hou, Buo-Jia Lu, Ya-Li Huang, Chih-Heng Chen, Chi-Huang Chen

Impact of oil-based contrast agents in hysterosalpingography on fertility outcomes in endometriosis: a retrospective cohort study

Baoli Xie, Yingqin Huang, Fu Hang, Jiaxin Yu, Qianwen Hu, Jiaxu Li, Aiping Qin

Progesterone-induced progesterone receptor membrane component 1 rise-to-decline changes are essential for decidualization

Hailun Liu, André Franken, Alexandra P. Bielfeld, Tanja Fehm, Dieter Niederacher, Zhongping Cheng, Hans Neubauer, Nadia Stamm

An integrated multi-tissue approach for endometriosis candidate biomarkers: a systematic review

Axelle Brulport, Mathilde Bourdon, Daniel Vaiman, Christian Drouet, Khaled Pocate-Cheriet, Kheira Bouzid, Louis Marcellin, Pietro Santulli, Carole Abo, Maxime Jeljeli, Sandrine Chouzenoux, Charles Chapron, Frédéric Batteux, Camille Berthelot, Ludivine Doridot

‘Intracytoplasmic sperm injection (ICSI) paradox’ and ‘andrological ignorance’: AI in the era of fourth industrial revolution to navigate the blind spots

  • Open Access
  • ICSI
  • Correspondence

Pallav Sengupta, Sulagna Dutta, Ravindran Jegasothy, Petr Slama, Chak-Lam Cho, Shubhadeep Roychoudhury

The reproductive potential of vitrified-warmed euploid embryos declines following repeated uterine transfers

A. Almohammadi, F. Choucair, L. El Taha, H. Burjaq, M. Albader, A. B. Cavanillas, Johnny T. Awwad

Deconvolution at the single-cell level reveals ovarian cell-type-specific transcriptomic changes in PCOS

Shumin Li, Yimeng Li, Yu Sun, Gengchen Feng, Ziyi Yang, Xueqi Yan, Xueying Gao, Yonghui Jiang, Yanzhi Du, Shigang Zhao, Han Zhao, Zi-Jiang Chen

Evaluation of serum adiponectin as a marker of insulin resistance in women with polycystic ovarian syndrome: a comparative cross-sectional study

Olugbenga Ojatokunbo Runsewe, Abiodun Adeniyi Adewunmi, Gbenga Olorunfemi, Abimbola Tawaqualit Ottun, Ayokunle Moses Olumodeji, Babalola Ogungbemile, Tamramat Iyabo Runsewe-Abiodun

Effect of frozen-thawed embryo transfer with a poor-quality embryo and a good-quality embryo on pregnancy and neonatal outcomes

  • Open Access
  • Research

Cheng Zeng, Rui-Hui Lu, Xin Li, Sheng Wang, Yan-Rong Kuai, Qing Xue

Assessment of artificial intelligence model and manual morphokinetic annotation system as embryo grading methods for successful live birth prediction: a retrospective monocentric study

Myrto-Sotiria Papamentzelopoulou, Ilectra-Niki Prifti, Despoina Mavrogianni, Thomais Tseva, Ntilay Soyhan, Aikaterini Athanasiou, Antonia Athanasiou, Adamantios Athanasiou, Paraskevi Vogiatzi, George Konomos, Dimitrios Loutradis, Maria Sakellariou

Flagellar beating forces of human spermatozoa with different motility behaviors

  • Open Access
  • Research

Cristina Tufoni, Alice Battistella, Stefania Luppi, Rita Boscolo, Giuseppe Ricci, Marco Lazzarino, Laura Andolfi

Active plasma renin concentration throughout healthy and complicated pregnancy: a systematic review and meta-analysis

Wisal El Fathi, Maaike van Ochten, Munieb Rehman, Sander M. J. van Kuijk, Joanna IntHout, Chahinda Ghossein-Doha, Sander de Haas, Marc E. A. Spaanderman, Joris van Drongelen

Pregnancy and obstetric outcomes of dichorionic triamniotic triplet pregnancies with selective foetal reduction after assisted reproductive technology

Shuhua Liu, Qianhua Xu, Dehong Liu, Qiuru Li, Jingyu Qian, Bin Zhang, Xianxia Chen

Liraglutide improved the reproductive function of obese mice by upregulating the testicular AC3/cAMP/PKA pathway

Ruibing Qi, Yuzhen Liang, Jinming Yu, Bing Chen, Jiaqin Jiang, Xingye Wu, Wensheng Lu, Zhengming Li

Predictive models of recurrent implantation failure in patients receiving ART treatment based on clinical features and routine laboratory data

Qunying Fang, Zonghui Qiao, Lei Luo, Shun Bai, Min Chen, Xiangjun Zhang, Lu Zong, Xian-hong Tong, Li-min Wu

A modern-day litmus test for the sustainability of daily IVF practice - Alabama supreme court ruling overreaches in asserting that frozen embryos are legally children

  • Open Access
  • Editorial

David B. Seifer

Survival in pregnancy-associated breast cancer patients compared to non-pregnant controls

María Martín Cameán, Ibon Jaunarena, Jose Ignacio Sánchez-Méndez, Covadonga Martín, Félix Boria, Elena Martín, Emanuela Spagnolo, Ignacio Zapardiel, Alicia Hernández Gutiérrez

Reproductive outcomes of dual trigger therapy with GnRH agonist and hCG versus hCG trigger in women with diminished ovarian reserve: a retrospective study

Kai Chen, Chunmei Zhang, Lixue Chen, Yue Zhao, Hongzhen Li

Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin

  • Open Access
  • Research

Lingling Wang, Ming Yan, Tiao Bu, Xiaolong Wu, Linxi Li, Bruno Silvestrini, Fei Sun, C. Yan Cheng, Hao Chen

Enhancing endometrial receptivity: the roles of human chorionic gonadotropin in autophagy and apoptosis regulation in endometrial stromal cells

  • Open Access
  • Research

Bin Wang, Mingxia Gao, Ying Yao, Haofei Shen, Hongwei Li, Jingjing Sun, Liyan Wang, Xuehong Zhang

The adipokines progranulin and omentin – novel regulators of basic ovarian cell functions

Alexander V Sirotkin, Zuzana Fabová, Barbora Loncová, Maria Bauerová, Abdel Halim Harrath

Effect of melatonin on developmental competence, mitochondrial distribution, and intensity of fresh and vitrified/thawed in vitro matured buffalo oocytes

  • Open Access
  • Research

Omaima Mohamed Kandil, Samar Mahfouz Abd El Rahman, Rania S. Ali, Esraa Aly Ismail, Nehad M. Ibrahim

Distinct actions of testicular endocrine and lumicrine signaling on the proximal epididymal transcriptome

  • Open Access
  • Research

Daiji Kiyozumi

Endometrial stem cells alleviate cisplatin-induced ferroptosis of granulosa cells by regulating Nrf2 expression

  • Open Access
  • Research

Rumeng Pan, Rongli Wang, Feiyan Cheng, Lihui Wang, Zhiwei Cui, Jing She, Xinyuan Yang

Age-related increase in live-birth rates of first frozen thaw embryo versus first fresh transfer in initial assisted reproductive technology cycles without PGT

Sarah F Wang, David B Seifer

Impact of dehydroepiandrosterone sulfate and free androgen index on pregnancy and neonatal outcomes in PCOS patients

Wen Zhao, Zeting Li, Bing Cai, Canquan Zhou, Qingyun Mai

Uterine infusion strategies for infertile patients with recurrent implantation failure: a systematic review and network meta-analysis

Qin Xie, Xiaozhen Quan, Yanli Lan, Xuezhou Yang

Correction: Predictive models of recurrent implantation failure in patients receiving ART treatment based on clinical features and routine laboratory data

Qunying Fang, Zonghui Qiao, Lei Luo, Shun Bai, Min Chen, Xiangjun Zhang, Lu Zong, Xian-hong Tong, Li-min Wu

Effects of quercetin on polycystic ovary syndrome in animal models: a systematic review and meta-analysis

Pingping Su, Chao Chen, Liang Pang, Kai Wu, Yun Sun

Advancements in fertility preservation strategies for pediatric male cancer patients: a review of cryopreservation and transplantation of immature testicular tissue

Zih-Yi Sung, Yong-Qi Liao, Jung-Hsiu Hou, Hong-Hsien Lai, Sung-Ming Weng, Hai-Wei Jao, Buo-Jia Lu, Chi-Huang Chen

Pregnancy and acromegaly: clinical outcomes of retrospectively analysed data from the German acromegaly registry

Anke Tönjes, Marleen Würfel, Marcus Quinkler, Ulrich J. Knappe, Jürgen Honegger, Nina Krause-Joppig, Konrad Bacher, Timo Deutschbein, Sylvère Störmann, Jochen Schopohl, Sebastian M. Meyhöfer, Almuth Meyer, Matthias Gruber, Stefanie Wortmann, Christine Klasen, Wolfram Karges, Frank Demtröder, Hanna Frenzke, Katharina Laubner, Reinhard Finke

Comparing the efficacy and pregnancy outcome of intrauterine balloon and intrauterine contraceptive device in the prevention of adhesion reformation after hysteroscopic adhesiolysis in infertile women: a prospective, randomized, controlled trial study

HaiXia Ding, Honghong Zhang, Rui Qiao, Ningxia Sun, Yixuan Ji, Wenjuan Pang, Wen Li, Qing Zhang

Fresh or frozen day 6 blastocyst transfer: is there still a question?

Lucile Ferreux, Mathilde Bourdon, Ahmed Chargui, Julie Firmin, Chloé Maignien, Pietro Santulli, Catherine Patrat, Khaled Pocate-Cheriet

The value of low-intensity pulsed ultrasound in reducing ovarian injury caused by chemotherapy in mice

Yi Zhou, Fengyu Zhu, Yuanyuan Zhou, Xuqing Li, Shuhan Zhao, Yiqing Zhang, Ying Zhu, Hongyan Li, Yunxia Cao, Chaoxue Zhang

Gonadotropin elevation is ootoxic to ovulatory oocytes and inhibits oocyte maturation, and activin decoy receptor ActRIIB:Fc therapeutically restores maturation

Lori R. Bernstein, Amelia C. L. Mackenzie, Charles L. Chaffin, Se-Jin Lee, Duane C. Kraemer, Istvan Merchenthaler

Does growth hormone supplementation of in vitro fertilization/intracytoplasmic sperm injection improve cumulative live birth rates in women with poor embryonic development in the previous cycle?

  • Open Access
  • ICSI
  • Research

Xitong Liu, Na Li, Dongyang Wang, Wen Wen, Li Tian, Hanying Zhou, Ben W. Mol, Juanzi Shi, Tao Wang

Surgical treatment and reproductive outcomes in caesarean scar pregnancy at a single center

Yan Lei, Xin Du, Yu Liu, Fangshu Le, Jianshan Zhou

Effect of cytoplasmic fragmentation on embryo development, quality, and pregnancy outcome: a systematic review of the literature

  • Open Access
  • ICSI
  • Review

Ariella Yazdani, Iman Halvaei, Catherine Boniface, Navid Esfandiari

In vitro fertilization outcome based on the detailed early luteal phase trajectory of hormones: a prospective cohort study

Lan N Vuong, Toan D Pham, Vu N A Ho, Anh T L Vu, Tuong M Ho, Claus Yding Andersen

A new insight on evaluation of the fertility and pregnancy outcome in patients with primary Sjögren syndrome: a propensity score matched study in multi-IVF centers

Ruolin Mao, Lixia Zhu, Rui Long, Juepu Zhou, Xiangfei Wang, Meng Wang, Tiantian Wang, Youzhu Li, Hui Long, Lei Jin

Enhancing clinical utility: deep learning-based embryo scoring model for non-invasive aneuploidy prediction

Bing-Xin Ma, Guang-Nian Zhao, Zhi-Fei Yi, Yong-Le Yang, Lei Jin, Bo Huang

Testing the generalizability and effectiveness of deep learning models among clinics: sperm detection as a pilot study

Jiaqi Wang, Yufei Jin, Aojun Jiang, Wenyuan Chen, Guanqiao Shan, Yifan Gu, Yue Ming, Jichang Li, Chunfeng Yue, Zongjie Huang, Clifford Librach, Ge Lin, Xibu Wang, Huan Zhao, Yu Sun, Zhuoran Zhang

The profile of steroid hormones in human fetal and adult ovaries

Paraskevi Vazakidou, Sara Evangelista, Tianyi Li, Laetitia L. Lecante, Kristine Rosenberg, Jacco Koekkoek, Andres Salumets, Agne Velthut-Meikas, Pauliina Damdimopoulou, Séverine Mazaud-Guittot, Paul A. Fowler, Pim E.G. Leonards, Majorie B.M. van Duursen

Clinical outcomes of single blastocyst transfer with machine learning guided noninvasive chromosome screening grading system in infertile patients

Xiaoxi Li, Yaxin Yao, Dunmei Zhao, Xiufeng Chang, Yi Li, Huilan Lin, Huijuan Wei, Haiye Wang, Ying Mi, Lei Huang, Sijia Lu, Weimin Yang, Liyi Cai

Effects of physical activity on infertility in reproductive females

Hanzhi Zhang, Lan Hua, Dan Liu, Xin Su, Jianlin Chen, Jingfei Chen

Dietary acid load and risk of diminished ovarian reserve: a case-control study

  • Open Access
  • Research

Rahele Ziaei, Abed Ghavami, Hatav Ghasemi-Tehrani, Minoo Movahedi, Maryam Hashemi, Maryam Hajhashemi, Mahshid Elyasi, Mahdi Vajdi, Maryam Kalatehjari

Determining the optimal daily gonadotropin dose to maximize the oocyte yield in elective egg freezing cycles

  • Open Access
  • Research

Raoul Orvieto, Anouk Savir Kadmon, Nira Morag, Aliza Segev-Zahav, Ravit Nahum

Predicting personalized cumulative live birth rate after a complete in vitro fertilization cycle: an analysis of 32,306 treatment cycles in China

Leizhen Xia, Shiyun Han, Jialv Huang, Yan Zhao, Lifeng Tian, Shanshan Zhang, Li Cai, Leixiang Xia, Hongbo Liu, Qiongfang Wu

Connecting the dots: the role of fatigue in female infertility

Wenzhu Li, Xiaoyan Huang, Yiqiu Wei, Tailang Yin, Lianghui Diao

Emerging trends in sperm selection: enhancing success rates in assisted reproduction

Xiang Zhang, Shuen Chao, Ningxin Ye, Dongfang Ouyang

Correction: Survival in pregnancy-associated breast cancer patients compared to non-pregnant controls

  • Open Access
  • Correction

María Martín Cameán, Ibon Jaunarena, Jose Ignacio Sánchez-Méndez, Covadonga Martí, Félix Boria, Elena Martín, Emanuela Spagnolo, Ignacio Zapardiel, Alicia Hernández Gutiérrez

The role of age and AMH on cumulative live birth rates over multiple frozen-thawed embryo transfer cycles: a study based on low prognosis patients of POSEIDON 3 and 4 groups

  • Open Access
  • Research

Lan Xia, Xiaowei Zhou, Xiaoling Wang, Shen Zhao, Xian Wu, Huihui Xu, Aijun Zhang, Zhihong Niu

The relationship between thyroid autoantibodies and X chromosome monosomy in the chorionic tissue of patients with missed miscarriage

Lu Zhao, Li Liu, Hua Yang

FMR1 allelic complexity in premutation carriers provides no evidence for a correlation with age at amenorrhea

Bárbara Rodrigues, Vanessa Sousa, Carolyn M. Yrigollen, Flora Tassone, Olatz Villate, Emily G. Allen, Anne Glicksman, Nicole Tortora, Sarah L. Nolin, António J. A. Nogueira, Paula Jorge

Associations between a normal-range free thyroxine concentration and ovarian reserve in infertile women undergoing treatment via assisted reproductive technology

  • Open Access
  • Research

Qiaoling Zhang, Dandan Zhang, Haoyuan Liu, Jinyun Fu, Li Tang, Meng Rao

Potential molecular mechanisms and clinical implications of piRNAs in preeclampsia: a review

Yuanxuan Ma, Bo Hou, Jinbao Zong, Shiguo Liu

LncRNA MALAT1 facilitates BM-MSCs differentiation into endothelial cells and ameliorates erectile dysfunction via the miR-206/CDC42/PAK1/paxillin signalling axis

Longhua Luo, Zixin Wang, Xuxian Tong, Tenxian Xiong, Minggen Chen, Xiang Liu, Cong Peng, Xiang Sun

9-cis-retinoic acid signaling in Sertoli cells regulates their immunomodulatory function to control lymphocyte physiology and Treg differentiation

  • Open Access
  • Research

Alicja Kamińska, Laura Pardyak, Sylwia Lustofin, Karolina Gielata, Zbigniew Arent, Agnieszka Pietsch-Fulbiszewska, Anna Hejmej

Clinical data-based modeling of IVF live birth outcome and its application

Liu Liu, Hua Liang, Jing Yang, Fujin Shen, Jiao Chen, Liangfei Ao

DNA methylation landscape in pregnancy-induced hypertension: progress and challenges

Fengying Deng, Jiahui Lei, Junlan Qiu, Chenxuan Zhao, Xietong Wang, Min Li, Miao Sun, Meihua Zhang, Qinqin Gao

The construction of machine learning-based predictive models for high-quality embryo formation in poor ovarian response patients with progestin-primed ovarian stimulation

Yu-Heng Xiao, Yu-Lin Hu, Xing-Yu Lv, Li-Juan Huang, Li-Hong Geng, Pu Liao, Yu-Bin Ding, Chang-Chun Niu

Improvement of early miscarriage rates in women with adenomyosis via oxytocin receptor antagonist during frozen embryo transfer-a propensity score-matched study

Po-Wen Lin, Chyi-Uei Chern, Chia-Jung Li, Pei-Hsuan Lin, Kuan-Hao Tsui, Li-Te Lin

Safety of embryo cryopreservation: insights from mid-term placental transcriptional changes

  • Open Access
  • Research

Qin-Yu Luo, Si-Wei Zhang, Hai-Yan Wu, Jia-Ying Mo, Jia-En Yu, Ren-Ke He, Zhao-Ying Jiang, Ke-Jing Zhu, Xue-Ying Liu, Zhong-Liang Lin, Jian-Zhong Sheng, Yu Zhang, Yan-Ting Wu, He-Feng Huang

Multiple collapses of blastocysts after full blastocyst formation is an independent risk factor for aneuploidy — a study based on AI and manual validation

Lei Jin, Keyi Si, Zhou Li, Hui He, Li Wu, Bingxin Ma, Xinling Ren, Bo Huang

Diaph1 knockout inhibits mouse primordial germ cell proliferation and affects gonadal development

Xin Zhao, Chunbiao Fan, Tongtong Qie, Xinrui Fu, Xiaoshuang Chen, Yujia Wang, Yuan Wu, Xinyao Fu, Kesong Shi, Wenlong Yan, Haiquan Yu

The impact of mitochondrial impairments on sperm function and male fertility: a systematic review

Minoo Vahedi Raad, Amir Masoud Firouzabadi, Maryam Tofighi Niaki, Ralf Henkel, Farzaneh Fesahat

Systematic evaluation of the efficacy of treatments for cesarean scar pregnancy

Haiying Sun, Juan Wang, Peiying Fu, Ting Zhou, Ronghua Liu

Effect of aromatase inhibitors for preventing ovarian hyperstimulation syndrome in infertile patients undergoing in vitro fertilization: a systematic review and meta-analysis

Linying Jiang, Yuhan Qiu, Lijuan Xu, Ruiqi Chang, Fan He

Nur77 improves ovarian function in reproductive aging mice by activating mitophagy and inhibiting apoptosis

  • Open Access
  • Research

Ying Yao, Bin Wang, Kaihua Yu, Ji Song, Liyan Wang, Xuehong Zhang, Yulan Li

Heat stress induced piRNA alterations in pachytene spermatocytes and round spermatids

  • Open Access
  • Research

Poonam Mehta, Shruti Sethi, Santosh Kumar Yadav, Gopal Gupta, Rajender Singh

Impact of elevated serum estradiol levels before progesterone administration on pregnancy outcomes in frozen-thawed embryo transfer for hormone replacement therapy

Jun Shuai, Qiaoli Chen, Siyan Wan, Xingyu Chen, Weiwei Liu, Hong Ye, Guoning Huang

Investigating developmental characteristics of biopsied blastocysts stratified by mitochondrial copy numbers using time-lapse monitoring

Chun-I Lee, Ching-Ya Su, Hsiu-Hui Chen, Chun-Chia Huang, En-Hui Cheng, Tsung-Hsien Lee, Pin-Yao Lin, Tzu-Ning Yu, Chung-I Chen, Ming-Jer Chen, Maw-Sheng Lee, Chien-Hong Chen

Varied cellular abnormalities in thin vs. normal endometrium in recurrent implantation failure by single-cell transcriptomics

  • Open Access
  • Research

Xiaoying Fu, Xiaoyan Guo, Han Xu, Yini Li, Bihui Jin, Xirong Zhang, Chongyi Shu, Yuhang Fan, Yiqi Yu, Yuqing Tian, Jiao Tian, Jing Shu

Association between tea, coffee and caffeine consumption and risk of female infertility: a cross-sectional study

Hanzhi Zhang, Sixu Qian, Jianlin Chen, Jingfei Chen

PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis

Beatrice Belmonte, Giovanni Di Lorenzo, Alessandro Mangogna, Barbara Bortot, Giorgio Bertolazzi, Selene Sammataro, Simona Merighi, Anna Martorana, Gabriella Zito, Federico Romano, Anna Giorgiutti, Cristina Bottin, Fabrizio Zanconati, Andrea Romano, Giuseppe Ricci, Stefania Biffi

Oxidative stress biomarkers in pregnancy: a systematic review

Abubakar Ibrahim, Martina Irwan Khoo, Engku Husna Engku Ismail, Nik Hazlina Nik Hussain, Anani Aila Mat Zin, Liza Noordin, Sarimah Abdullah, Zaleha Abdullah Mahdy, Nik Ahmad Zuky Nik Lah

Genetic insights into the complexity of premature ovarian insufficiency

  • Open Access
  • Review

Linhang Nie, Xiaojie Wang, Songyuan Wang, Zhidan Hong, Mei Wang

Bioengineered 3D ovarian model for long-term multiple development of preantral follicle: bridging the gap for poly(ε-caprolactone) (PCL)-based scaffold reproductive applications

  • Open Access
  • Research

Chiara Di Berardino, Alessia Peserico, Chiara Camerano Spelta Rapini, Liliana Liverani, Giulia Capacchietti, Valentina Russo, Paolo Berardinelli, Irem Unalan, Andrada-Ioana Damian-Buda, Aldo R. Boccaccini, Barbara Barboni

IVF laboratory management through workflow-based RFID tag witnessing and real-time information entry

  • Open Access
  • Methodology

Man-Xi Jiang, Lei Guo, Sen Li, Xiao-Feng Xiao, Wei Chen, Shao-Qing Chen, Nan-Qiao Chen, Yuan-Yuan Sun, Guang-Li Zhang, Xiao-Hai Zeng, Yan-Mei Xiao, Li-Hua Fan

Analysis of assisted reproductive outcomes for gynecologic cancer survivors: a retrospective study

Jing Lin, Tianying Yang, Lu Li, Xiaoxi Sun, He Li

Liraglutide improves follicle development in polycystic ovary syndrome by inhibiting CXCL10 secretion

Min Zhao, Baoying Liao, Chuyu Yun, Xinyu Qi, Yanli Pang

Correction: DNA methylation landscape in pregnancyinduced hypertension: progress and challenges

  • Open Access
  • Correction

Fengying Deng, Jiahui Lei, Junlan Qiu, Chenxuan Zhao, Xietong Wang, Min Li, Miao Sun, Meihua Zhang, Qinqin Gao

Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis

Julia Delenko, Xiangying Xue, Prodyot K Chatterjee, Nathaniel Hyman, Andrew J Shih, Robert P Adelson, Polona Safaric Tepes, Peter K Gregersen, Christine N Metz

Factors affecting biochemical pregnancy loss (BPL) in preimplantation genetic testing for aneuploidy (PGT-A) cycles: machine learning-assisted identification

José A. Ortiz, B. Lledó, R. Morales, A. Máñez-Grau, A. Cascales, A. Rodríguez-Arnedo, Juan C. Castillo, A. Bernabeu, R. Bernabeu

Predictive value of Vitamin D levels in pregnant women on gestational length and neonatal weight in China: a population-based retrospective study

Qi Chen, Yuqing Chu, Ruixue Liu, Yang Lin

Molecular regulation of DNA damage and repair in female infertility: a systematic review

Xiuhua Xu, Ziwei Wang, Luyi Lv, Ci Liu, Lili Wang, Ya-nan Sun, Zhiming Zhao, Baojun Shi, Qian Li, Gui-min Hao

Identification of energy metabolism anomalies and serum biomarkers in the progression of premature ovarian failure via extracellular vesicles’ proteomic and metabolomic profiles

Zhen Liu, Qilin Zhou, Liangge He, Zhengdong Liao, Yajing Cha, Hongyu Zhao, Wenchao Zheng, Desheng Lu, Sheng Yang

Single-cell RNA sequencing reveals the effects of high-fat diet on oocyte and early embryo development in female mice

Qi Zhu, Feng Li, Hao Wang, Xia Wang, Yu Xiang, Huimin Ding, Honghui Wu, Cen Xu, Linglin Weng, Jieyu Cai, Tianyue Xu, Na Liang, Xiaoqi Hong, Mingrui Xue, Hongshan Ge

Consideration of hormonal changes for orthodontic treatment during pregnancy and lactation - a review

Yujie Zhao, Shengqi Qian, Zhijun Zheng, Juxiang Peng, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao

Effect of LH level on HCG trigger day on clinical outcomes in patients with diminished ovarian reserve undergoing GnRH-antagonist protocol

Qianjie Zhang, Kexin Zhang, Yu Gao, Shaojing He, Yicen Meng, Lei Ming, Tailang Yin, Jing Yang, Shuang Wu, Zhongming Zhou, Wei Li, Saijiao Li

Uric acid and risk of gestational diabetes mellitus: an observational study and mendelian randomization analysis

Nuerbiya Xilifu, Rui Zhang, Yongling Dai, Miyeshaer Maimaiti, Zhangyan Li, Ju Yang, Shufei Zang, Jun Liu

Correction: Varied cellular abnormalities in thin vs. normal endometrium in recurrent implantation failure by single-cell transcriptomics

  • Open Access
  • Correction

Xiaoying Fu, Xiaoyan Guo, Han Xu, Yini Li, Bihui Jin, Xirong Zhang, Chongyi Shu, Yuhang Fan, Yiqi Yu, Yuqing Tian, Jiao Tian, Jing Shu

The role of ubiquitin-conjugating enzyme in the process of spermatogenesis

Peng Lv, Jihong Liu, Xiaming Liu

Vaginal and endometrial microbiome dysbiosis associated with adverse embryo transfer outcomes

Weijue Su, Chaochao Gong, Haoyue Zhong, Huaqing Yang, Yuyan Chen, Xiaoyuan Wu, Jing Jin, Haitao Xi, Junzhao Zhao

The prediction of semen quality based on lifestyle behaviours by the machine learning based models

  • Open Access
  • Research

Aykut Aykaç, Coşkun Kaya, Özer Çelik, Mehmet Erhan Aydın, Mustafa Sungur

Fance deficiency impaired DNA damage repair of prospermatogonia and altered the repair dynamics of spermatocytes

Huan Yin, Zhixian Zhou, Chun Fu

Correction: The thrombospondin-1 receptor CD36 is an important mediator of ovarian angiogenesis and folliculogenesis

  • Open Access
  • Correction

Kata Osz, Michelle Ross, Jim Petrik

Correction: IVF laboratory management through workflow-based RFID tag witnessing and real-time information entry

  • Open Access
  • Correction

Man-Xi Jiang, Lei Guo, Sen Li, Xiao-Feng Xiao, Wei Chen, Shao-Qing Chen, Nan-Qiao Chen, Yuan-Yuan Sun, Guang-Li Zhang, Xiao-Hai Zeng, Yan-Mei Xiao, Li-Hua Fan

Enhancing predictive models for egg donation: time to blastocyst hatching and machine learning insights

Jorge Ten, Leyre Herrero, Ángel Linares, Elisa Álvarez, José Antonio Ortiz, Andrea Bernabeu, Rafael Bernabéu

Effect of estradiol supplementation on luteal support following a significant reduction in serum estradiol levels after hCG triggering: a prospective randomized controlled trial

Na Li, Yu Huang, LiJuan Fan, Zan Shi, He Cai, JuanZi Shi, Hui Wang

Asiaticoside ameliorates uterine injury induced by zearalenone in mice by reversing endometrial barrier disruption, oxidative stress and apoptosis

  • Open Access
  • Research

Ge Gao, Hongyang Jiang, Hai Lin, Hongfeng Yang, Ke Wang

Discussion on the evaluation of the therapeutic efficacy of uterine artery blood flow parameters and serum PLGF and sFlt-1 in patients with recurrent spontaneous abortion

Xiaolu Lian, Yanyu Zhong, Ying Zhou, Fei Xia, Ru Sun

Identifying key predictive features for live birth rate in advanced maternal age patients undergoing single vitrified-warmed blastocyst transfer

  • Open Access
  • Research

Lidan Liu, Bo Liu, Ming Liao, Qiuying Gan, Qianyi Huang, Yihua Yang

GnRH agonist pretreatment for frozen embryo transfer among women with polycystic ovary syndrome: a narrow systematic review and meta-analysis of randomized controlled trials

Yiqing Wu, Mixue Tu, Yifeng Liu, Dan Zhang

Patients with low prognosis in ART: a Delphi consensus to identify potential clinical implications and measure the impact of POSEIDON criteria

  • Open Access
  • Research

Carlo Alviggi, Peter Humaidan, Robert Fischer, Alessandro Conforti, Michael H. Dahan, Antonio La Marca, Raoul Orvieto, Nikolaos P. Polyzos, Matheus Roque, Sesh K. Sunkara, Filippo Maria Ubaldi, Lan Vuong, Hakan Yarali, Thomas D’Hooghe, Salvatore Longobardi, Sandro C. Esteves

Beyond Earth’s bounds: navigating the frontiers of Assisted Reproductive Technologies (ART) in space

  • Open Access
  • ICSI
  • Review

Olga Chaplia, Begum Aydogan Mathyk, Stephanie Nichols-Burns, Murat Basar, Cihan Halicigil

The PPOS protocol mitigates the detrimental effects of high BMI on embryo and clinical pregnancy outcomes

Xi Shen, Menghui Li, Yunhan Nie, Jiqiang Si, Yali Liu, Tiantian Wang, Hongyuan Gao, Kaibo Lin, Li Wang

Intraovarian injection of 3D-MSC-EVs-ECM gel significantly improved rat ovarian function after chemotherapy

Yaping Zhang, Dong Li, Yi Han, Min Wu, Shule Zhang, Huixian Ma, Linghong Liu, Xiuli Ju

Impact of letrozole co-treatment in an antagonist protocol for IVF/ICSI: a retrospective study

Jing Lin, Fenglu Wu, Bian Wang, Qianqian Zhu, Jiaying Lin

RETRACTED ARTICLE: Melatonin levels and embryo quality in IVF patients with diminished ovarian reserve: a comparative study

Yingying Wang, Shangjie Liu, Feifei Gan, Dan Xiong, Xiuming Zhang, Zhou Zheng

Does hCG-trigger in the mild stimulation protocol for endometrial preparation have any effect on pregnancy outcome in frozen-thawed embryo transfer?

Samaneh Kashi, Arezoo Arabipoor, Zahra Zolfaghari, Bahar Movaghar, Hanieh Rostami, Maryam Hafezi

A method for determining potential parental contamination: linkage disequilibrium-based log-likelihood ratio analysis for IVF-PGT

Le Bo, Fangfang Dong, Zhinan Wu, Anwen Zhou, Yulan Zhang, Lingyin Kong, Lei Zhan, Naru Lu, Lina Qi, Tingting Sun, Bo Liang, Caiping Mao

Identify high-risk DOR women ≤ 35 years old following assisted reproduction technology through cutoffs of anti-mullerian hormone and antral follicle counts

Yili Teng, Peipei Pan, Chang Liu, Yue Lin, Xiaozhu Zhu, Suichun Wu, Haiyan Yang, Xuefeng Huang, Fang Lian

Awareness and acceptability of assisted reproductive technology among non-medical tertiary students in a low-resource setting

Abigail Charity Johnson-Ekeleba, Promise Emmanuel Sefogah, Alim Swarray-Deen, Kareem Mumuni

Non-invasively predicting euploidy in human blastocysts via quantitative 3D morphology measurement: a retrospective cohort study

  • Open Access
  • Research

Guanqiao Shan, Khaled Abdalla, Hang Liu, Changsheng Dai, Justin Tan, Junhui Law, Carolyn Steinberg, Ang Li, Iryna Kuznyetsova, Zhuoran Zhang, Clifford Librach, Yu Sun

MTHFR C677T、MTHFR A1298C、MTRR A66G and MTR A2756G polymorphisms and male infertility risk: a systematic review and meta-analysis

Feng Li, Ju-ju Qi, Li-xin Li, Teng-fei Yan

Retraction Note: The proto-oncogene c-src is involved in primordial follicle activation through the PI3K, PKC and MAPK signaling pathways

  • Open Access
  • Retraction Note

Xiao-Yu Du, Jian Huang, Liang-Quan Xu, Dan-Feng Tang, Lei Wu, Li-Xia Zhang, Xiao-Ling Pan, Wei-Yun Chen, Li-Ping Zheng, Yue-Hui Zheng

17α-Ethynylestradiol alters testicular epigenetic profiles and histone-to-protamine exchange in mice

L. Ded, E. Zatecka-Lanska, E. Vaculikova, M. Frolikova, O. Sanovec, V. Palenikova, O. Simonik, A. Dorosh, H. Margaryan, F. Elzeinova, A. Kubatova, J. Peknicova, A. Paradowska-Dogan, K. Steger, K. Komrskova

Correction: Predictive models of recurrent implantation failure in patients receiving ART treatment based on clinical features and routine laboratory data

  • Open Access
  • Correction

Qunying Fang, Zonghui Qiao, Lei Luo, Shun Bai, Min Chen, Xiangjun Zhang, Lu Zong, Xian-hong Tong, Li-min Wu

Human umbilical cord mesenchymal stem cells restore chemotherapy-induced premature ovarian failure by inhibiting ferroptosis in vitro ovarian culture system

Jiaqi Chen, Zhuoying He, Wenjuan Xu, Yumiao Kang, Fengyu Zhu, Heng Tang, Jianye Wang, Fei Zhong

Melatonin supplementation attenuates cuproptosis and ferroptosis in aging cumulus and granulosa cells: potential for improving IVF outcomes in advanced maternal age

Kuan-Hao Tsui, Chia-Jung Li, Li-Te Lin

MicroRNAs, endometrial receptivity and molecular pathways

  • Open Access
  • Review

Soheila Salmasi, Mohammad Saeed Heidar, Mahmood Khaksary Mahabady, Bahman Rashidi, Hamed Mirzaei

Identification of novel variants and candidate genes in women with 46,XX complete gonadal dysgenesis

Leilei Ding, Shan Deng, Pan Zhang, Duoduo Zhang, Qinjie Tian

Concerning influences of micro/nano plastics on female reproductive health: focusing on cellular and molecular pathways from animal models to human studies

Hasti Balali, Ali Morabbi, Mohammad Karimian

The role of viral infection in implantation failure: direct and indirect effects

Marzieh Rezaei, Mohsen Moghoofei

Cordycepin improves hyperactivation and acrosome reaction through adenosine receptors during human sperm capacitation in vitro

  • Open Access
  • Research

Lijun Shan, Linmei Gao, Yuhao Chai, Kun Li, Jianmin Yu, Fei Liang, Jiangfeng Qin, Ya Ni, Peibei Sun

Age-related testosterone decline: mechanisms and intervention strategies

Haoyang Cheng, Xiaoyan Zhang, Yongheng Li, Dezhong Cao, Chenglong Luo, Qi Zhang, Sizheng Zhang, Yongzheng Jiao

Correlation between cardiometabolic index and female infertility: a cross-sectional analysis

Yiran Zhao, Weihui Shi, Yang Liu, Ningxin Qin, Hefeng Huang

Analysis of single-cell RNA sequencing in human oocytes with diminished ovarian reserve uncovers mitochondrial dysregulation and translation deficiency

  • Open Access
  • Research

Xin Li, Xingwu Wu, Hui Zhang, Peipei Liu, Leizhen Xia, Nana Zhang, Lifeng Tian, Zengming Li, Jing Lu, Yan Zhao, Jun Tan

Levonorgestrel at emergency contraception dose has no effect on ciliary beat frequency and muscular contraction of the human fallopian tube: an in vitro experimental study

Raymond Hang Wun Li, Su-Bin Liao, William Shu Biu Yeung, Ernest Hung Yu Ng, Wai Sum O, Pak Chung Ho

Association of insulin resistance surrogate indices and erectile dysfunction: a systematic review and meta-analysis

Sayeh Jalali, Negar Zareshahi, Amir Hossein Behnoush, Alireza Azarboo, Amirhossein Shirinezhad, Seyyed Yasin Hosseini, Amin Javidan, Amirhossein Ghaseminejad-Raeini

Effect of serum uric acid level on reproductive outcome in women without polycystic ovary syndrome undergoing in vitro fertilization

Leizhen Xia, Lu Fan, Jialyu Huang, Yan Zhao, Lifeng Tian, Houyang Chen, Li Cai, Qiongfang Wu, Leixiang Xia

Dendritic cells under the control of the preimplantation embryo secretome: an in vitro study

Christiana Kyvelidou, Sofia Haselrieder, Maria von Gierke, Johanna M. Gostner, Wolfgang Biasio, Barbara Wirleitner, Christine Heufler, Bettina Toth, Susanne Hofer-Tollinger

Integrated bioinformatics analysis reveals that CCBP2 and GPR87 are new GPCR-associated biomarkers for preeclampsia

Jie Li, Meng-Meng Chen, Bingqiang Zhang, Yi Zhao

Age-related uterine changes and its association with poor reproductive outcomes: a systematic review and meta-analysis

  • Open Access
  • Review

Diana Marti-Garcia, Asunta Martinez-Martinez, Francisco Jose Sanz, Almudena Devesa-Peiro, Patricia Sebastian-Leon, Nataly del Aguila, Antonio Pellicer, Patricia Diaz-Gimeno

Whole-exome sequencing and Drosophila modelling reveal mutated genes and pathways contributing to human ovarian failure

Ismael Henarejos-Castillo, Francisco José Sanz, Cristina Solana-Manrique, Patricia Sebastian-Leon, Ignacio Medina, José Remohi, Nuria Paricio, Patricia Diaz-Gimeno

Is oral dydrogesterone equivalent to vaginal micronized progesterone for luteal phase support in women receiving oocyte donation?

Margaux Lorillon, Geoffroy Robin, Laura Keller, Emeline Cailliau, Clémence Delcourt, Virginie Simon, Christine Decanter, Sophie Catteau-Jonard

Pre-pregnancy LDL/HDL and total Cholesterol/HDL ratios are strong predictors of gestational diabetes mellitus in women undergoing assisted reproductive technologies

Yvonne Liu, Johann-Georg Hocher, Shujuan Ma, Liang Hu, Huijun Chen, Xiaoli Zhang, Fei Gong, Bernhard K. Krämer, Ge Lin, Berthold Hocher

Contrast induced nephropathy in women with infertility undergoing hysterosalpingography

Akin Usta, Ceyda Sancakli Usta, Duygu Lafci, Tuncay Kiris, Eyup Avci

Müllerian anomalies and endometriosis: associations and phenotypic variations

Surya Bhamidipaty-Pelosi, Isaac Kyei-Barffour, Marianna Volpert, Nora O’Neill, Alyssa Grimshaw, Lars Eriksson, Alla Vash-Margita, Emanuele Pelosi

Correction: Downregulated DUXAP8 lncRNA impedes trophoblast cell proliferation and migration by epigenetically upregulating TFPI2 expression

  • Open Access
  • Correction

Xiaotong Tang, Yueying Cao, Dan Wu, Lizhou Sun, Yetao Xu

Oxidative stress and energy metabolism abnormalities in polycystic ovary syndrome: from mechanisms to therapeutic strategies

Heqiu Yan, Li Wang, Guohui Zhang, Ningjing Li, Yuhong Zhao, Jun Liu, Min Jiang, Xinrong Du, Qin Zeng, Dongsheng Xiong, Libing He, Zhuoting Zhou, Mengjun Luo, Weixin Liu

Dec 23
Issue: 1/2023
May 25
Issue: Special Issue 1/2025
Luteinizing Hormone throughout the fertility journey

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