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Multiple Pregnancy 

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  1. Open Access 01-12-2024 | Folic Acid | OriginalPaper

    Adherence and acceptability of multiple micronutrient supplementation during pregnancy: Study protocol for a cluster-randomized non-inferiority trial in Cambodia

    Title {1} Adherence and acceptability of multiple micronutrient supplementation among pregnant women in Cambodia: A cluster-randomized non-inferiority trial Trial registration {2a and 2b} NCT05867836 Protocol version {3} Version 4_May 22, 2023 …

  2. Open Access 03-04-2024 | Cladribine | Online First

    Pregnancy effect on disease activity in women with multiple sclerosis treated with cladribine

    Multiple sclerosis (MS) is an autoimmune and neurodegenerative disorder of the central nervous system (CNS) characterized by a young age at onset and a female sex predominance [ 1 ]. Hormonal and immune changes occurring during pregnancy may …

  3. 30-03-2024 | Methotrexate | Online First

    Effect of Single and Multiple Methotrexate Doses Treatment on Ovarian Reserve in Ectopic Pregnancy Women: A Prospective Cohort Study

    One of the main concerns for women diagnosed with ectopic pregnancy (EP) is the potential adverse effect of the treatment techniques on ovarian reserve and fertility preservation [ 1 ]. EP complicates about 1–2% of all pregnancies, which could lead …

  4. Open Access 01-12-2024 | Pre-Eclampsia | OriginalPaper

    Integrating multiple lines of evidence to assess the effects of maternal BMI on pregnancy and perinatal outcomes

    Obesity is a leading preventable cause of ill health, mortality, and morbidity across the world and affects 10% and 25% of adult women in low- and high-income countries, respectively [ 1 ]. Higher maternal pre-pregnancy body mass index (BMI) is …

  5. Open Access 01-12-2023 | Premature Birth | OriginalPaper

    Epidemiology and factors associated with preterm births in multiple pregnancy: a retrospective cohort study

    Since 1980, there has been a 76% increase in multiple pregnancy (defined as a pregnancy with two or more fetuses such as triplets or quadruplets) – a trend that continues to this day [ 1 ]. These pregnancies are deemed high-risk, often leading to …

  6. Open Access 01-12-2023 | Multiple Sclerosis | OriginalPaper

    Prominent epigenetic and transcriptomic changes in CD4+ and CD8+ T cells during and after pregnancy in women with multiple sclerosis and controls

    Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS), to a large degree driven by T cell-mediated inflammation [ 1 ]. Despite recent advances in immunomodulatory treatments, many people with MS continue to …

  7. Open Access 01-12-2023 | Hyperglycemia | OriginalPaper

    Impact of experiencing multiple vulnerabilities on fetal growth and complications in women with hyperglycemia in pregnancy

    The pooled global standardized prevalence of gestational diabetes mellitus (GDM) was estimated at 14.0% by Wang et al. using data from studies conducted between 1990–2020 [ 1 ]. In terms of regional values, standardized prevalence in Europe was …

  8. 28-01-2023 | Ectopic Pregnancy | OriginalPaper

    Validation of a multiple marker test for early pregnancy outcome prediction

    In a field of consistently improving techniques and technologies, the distinction between a normal versus abnormal early pregnancy remains a vexing clinical challenge for health care providers and their female patients. The importance of being …

  9. 07-06-2023 | Multiple Pregnancy | OriginalPaper

    Elective Single Cleavage-Stage Embryo Transfer in IVF Patients with Suboptimal Ovarian Response is Not Detrimental to Cumulative Pregnancy and Reduces Multiple Pregnancy Rates.

    In recent years, multiple higher-order pregnancies in in vitro fertilization (IVF) programs have dropped significantly due to the evolution of embryo culture and selection techniques as well as specific legal constraints in some countries trending …

  10. 26-06-2023 | Magnetic Resonance Imaging | OriginalPaper

    Brain MRI activity during the year before pregnancy can predict long-term clinical worsening in patients with Multiple Sclerosis

    Multiple sclerosis (MS) is the most common disabling neurological disease affecting young adults aged 20–45 years [ 1 ]. In adults, a pronounced sex disparity is evident in MS cases, with females being affected more often than males at …

  11. Open Access 10-02-2023 | Lactation | OriginalPaper

    Bone Microarchitecture and Strength Changes During Teriparatide and Zoledronic Acid Treatment in a Patient with Pregnancy and Lactation-Associated Osteoporosis with Multiple Vertebral Fractures

    Pregnancy- and lactation-associated osteoporosis (PLO) is a rare form of osteoporosis, of which the pathogenesis and best treatment options are unclear. In this report, we describe the case of a 34-year old woman diagnosed with severe osteoporosis …

  12. Open Access 01-12-2023 | Malaria | OriginalPaper

    Perceptions and drivers of healthcare provider and drug dispenser practices for the treatment of malaria in pregnancy in the context of multiple first-line therapies in western Kenya: a qualitative study

    About 89% of all pregnancies in the World Health Organization (WHO) Africa region (AFRO) were at risk of malaria infection, and 32% had an infection during pregnancy in 2021 [ 1 , 2 ]. Malaria in pregnancy is associated with severe maternal …

  13. Open Access 03-07-2022 | Multiple Sclerosis | OriginalPaper

    Abuse and revictimization in adulthood in multiple sclerosis: a cross-sectional study during pregnancy

    People with multiple sclerosis (MS) are more often exposed to abuse and neglect in childhood than the general population [ 1 – 4 ]. Mistreatment in childhood is a strong predictor of abuse later in life, known as revictimization [ 5 ]. It is not …

  14. Open Access 01-12-2023 | Malaria | OriginalPaper

    Healthcare provider and drug dispenser knowledge and adherence to guidelines for the case management of malaria in pregnancy in the context of multiple first-line artemisinin-based combination therapy in western Kenya

    Malaria remains a significant public health challenge and a major cause of morbidity and mortality. In 2021, 247 million cases were reported, with 89% of all pregnancies in the World Health Organization Africa region (WHO AFRO) at risk of …

  15. Open Access 01-04-2022 | Natalizumab | ReviewPaper

    Monoclonal Antibodies in the Treatment of Relapsing Multiple Sclerosis: an Overview with Emphasis on Pregnancy, Vaccination, and Risk Management

    Monoclonal antibodies have become a mainstay in the treatment of patients with relapsing multiple sclerosis (RMS) and provide some benefit to patients with primary progressive MS. They are highly precise by specifically targeting molecules …

  16. Open Access 01-03-2022 | Magnetic Resonance Imaging | OriginalPaper

    Effects of Pregnancy and Breastfeeding on Clinical Outcomes and MRI Measurements of Women with Multiple Sclerosis: An Exploratory Real-World Cohort Study

    Pregnancy represents an important event in many women’s lives. The profound hormonal changes that accompany this phase often impact the course of multiple sclerosis (MS). Many studies to date have focused on this topic. Studies agree that the …

  17. 01-08-2021 | Contraception | BriefCommunication

    Pregnancy outcomes in alemtuzumab treated women with multiple sclerosis: a case series

    Data on pregnancy outcome in alemtuzumab-treated women are scarce and derived from safety reports of clinical trials. We report on seven women with overall eight pregnancies during treatment with alemtuzumab in a real-world setting. All …

  18. Open Access 01-12-2021 | Multiple Sclerosis | OriginalPaper

    Outcomes of pregnancy in Egyptian women with multiple sclerosis in the new treatment era: a multi-center retrospective observational study

    Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system (CNS) of adults, especially women during the childbearing period [ 1 ]. Therefore, pregnancy-associated conditions like lactation are major concerns that should …

  19. 01-02-2021 | Multiple Myeloma | Report

    Pregnancy and Its Successful Outcome in a Patient with Multiple Myeloma

    Multiple myeloma is a B-cell neoplastic disorder and represents 1% of all cancers and 13% of hematological malignancies. It is predominantly a disease of elderly, and less than 3% of all cases are below the age of 40 years. We present the case of …

  20. 01-01-2021 | Hypertension | ReviewPaper

    Multiple Gestations and Hypertensive Disorders of Pregnancy: What Do We Know?

    The incidence of multifetal gestations in the USA, especially twins, has nearly doubled in the last four decades [ 1 ]. From 1980 to 2009, the rate increased from 18.9 to 33.3 per 1000 livebirths [ 2 ]. This number was stable between 2009 and 2012 …

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