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Cancer and Metastasis Reviews

1997 - 2023
Volumes
88
Issues
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Issue 2/2023
Histones and Histone Modifiers in Tumor Progression and Metastasis
Latest issue

About this journal

The transformation of biology from a descriptive, phenomenological discipline to one in which the regulatory principles are understood and predictably manipulated brings new opportunities to the study of cancer and the search for effective therapeutic modalities. Cancer and Metastasis Reviews offers a forum for critical review and discussion of these challenges.


Each issue presents five to seven different contributions on a single theme or topic, with an introductory essay from a distinguished individual in the field. Special emphasis is placed on subjects of relevance to the molecular and cellular biology of cancer metastasis and tumor progression, as well as to the treatment of metastatic disease. Occasional issues will be devoted to an in-depth clinical and biological analysis of a particular type of cancer.


The journal also reviews important recent developments in the biology and treatment of malignant disease, and highlights promising new directions.

Metadata
Title
Cancer and Metastasis Reviews
Coverage
Volume 16/1997 - Volume 42/2023
Publisher
Springer US
Electronic ISSN
1573-7233
Print ISSN
0167-7659
Journal ID
10555
DOI
https://doi.org/10.1007/10555.1573-7233

Navigating the Treatment of Renal Cell Carcinoma

Insights on the Current Treatment Landscape and Managing Patient Health

In recent years, tremendous efforts have been made in the medical treatment of metastatic renal cell carcinoma (mRCC), with Immune-Oncological combinations standing as the current standard of care in the first-line setting of mRCC. 

In these podcasts, expert authors discuss the current treatment landscape for these new therapies and discuss what should be taken into account when choosing the most appropriate treatment for their patients so as to balance oncological outcomes, adverse events and quality of life.

Supported by an unrestricted educational grant from Eisai Europe Limited.

Listen now

Test your knowledge with Case-Based Clinical Insights

Oncology and Hematology Cases

A 28-year-old male patient (188 cm, 72 kg) presents to the central emergency department with dorsal pain after returning from a trip to East Asia. He reports feeling a bit tired and listless without classic signs of infection. In the clinical examination, apart from an approximately fist-sized, deeply situated, sturdy and non-displaceable bulging of the abdominal wall sinistrally paraumbilically, a slight enlargement of the left testis with pain upon palpation is noticeable. What is your first suspicion, and what are your first diagnostic steps?

The 46-year-old male patient has been showing various signs of inflammation for 6–8 weeks: Sore throat, canker sores, joint pain and febrile rhinitis. There is an unintended weight loss of 2–3 kg. Physical examination reveals findings that are inconspicuous for the patient’s age. How do you proceed now?

A 76-year-old, overweight female patient with anaemia and type II diabetes noted by her family doctor presents with fatigue, forgetfulness and yellowish pallor in a neglected state. Moreover, she shows an increasingly unsteady gait. How do you proceed?

A 56-year-old man presents with concentration problems, dorsal pain, fatigue and a marked increase in urination. His family history is positive for bronchial carcinoma. Physical examination reveals tenderness upon percussion in the lumbar spine. How do you proceed?