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33424 search results for:

Lung Transplantation 

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  1. Open Access 01-12-2024 | Pneumothorax | OriginalPaper

    Native-lung complications following single-lung transplantation for interstitial lung disease: an in-depth analysis

    In performing lung transplantation (LTx) in regions with severe donor shortages, such as Japan, single-lung transplantation (SLTx) is often preferred over bilateral lung transplantation (BLTx) because of the critical need for available organs [ 1 – …3

  2. 25-04-2024 | Pneumonectomy | Online First

    Native lung surgery after single lung transplantation: clinical characteristics and outcomes

    Lung transplantation is a viable option for patients with end-stage pulmonary parenchymal and vascular diseases for which all medical therapies have failed. In Japan, 108 lung transplants were performed in 2022, of which 48 were single lung

  3. Open Access 01-12-2024 | Chronic Obstructive Lung Disease | OriginalPaper

    Double lung transplantation is better than single lung transplantation for end-stage chronic obstructive pulmonary disease: a meta-analysis

    Chronic obstructive pulmonary disease (COPD) is the most common indication for lung transplantation worldwide 1 . Currently, lung transplantation is the final treatment strategy for patients with end-stage COPD. The points in favor of single lung

  4. 22-03-2024 | Lung Transplantation | Online First

    Surveillance Biopsy After Lung Transplantation — Is It Necessary?

    In people undergoing lung transplantation, graft function can be monitored via routinely scheduled surveillance biopsies or via noninvasive assessments. But which approach is best?

  5. Open Access 01-12-2024 | ECMO | OriginalPaper

    Two single lung transplantations from one donor: lung twinning in the LAS era

    Since the Lung Allocation Score (LAS) was introduced in Germany in 2011 a decreased number of deaths among patients on the waiting list could be documented [ 1 ]. Nevertheless death on the waiting list remains a clinical challenge due to severe …

  6. Open Access 01-12-2024 | ECMO | OriginalPaper

    Heparin-free veno-arterial extracorporeal membrane oxygenation in lung transplantation: a retrospective cohort study

    Lung transplantation (LTx) is considered a last resort for patients with severe lung disease, and anesthesia during the procedure poses significant challenges. Extracorporeal life support is frequently employed in lung transplantation (LTx). In …

  7. 15-04-2024 | Pulmonary Hypertension | Online First

    Effect of revised organ transplant law in Japan on lung transplantation

    Since the first successful lung transplantation, in Toronto in 1983, approximately 4,000 lung transplant procedures have been performed annually world-wide, according to the international thoracic organ transplant registry collected by the …

  8. Open Access 08-04-2024 | Arterial Diseases | Online First

    The role of coronary artery disease in lung transplantation: a propensity-matched analysis

    Advanced lung disease is associated with severely impaired quality of life and dramatically reduced life expectancy [ 1 – 3 ]. Though well established, lung transplantation as the ultimate therapeutic option is highly limited by the scarcity of …

  9. Open Access 01-12-2024 | ECMO | OriginalPaper

    Impact of recipient and donor pretransplantation body mass index on early postosperative complications after lung transplantation

    Body mass index (BMI) is the reference tool that defines underweight, normal weight, overweight and obese individuals according to the World Health Organization [ 1 ]. In lung transplantation (LT), the 2021 report of the International Society for …

  10. Open Access 01-06-2024 | ECMO | OriginalPaper

    Anesthesia for lung transplantation in children under 12 years of age: a single center experience of China

    In terms of irreversible, progressive lung parenchymal or vascular disease, pediatric lung transplantation has emerged as a life-saving option. However, advances in this field remains limited due to the difficulty in finding matching donors …

  11. Open Access 06-04-2024 | Tacrolimus | Online First

    Tacrolimus Variability and Clinical Outcomes in the Early Post-lung Transplantation Period: Oral Versus Continuous Intravenous Administration

    Tacrolimus-based immunosuppressive regimes are considered standard of care after lung transplantation (LuTx) [ 1 ]. Nonetheless, tacrolimus is known to have a narrow therapeutic range and high interindividual pharmacokinetic (PK) variability …

  12. Open Access 28-03-2024 | Kidney Transplantation | Online First

    Lung cancer after kidney transplantation: a 50-year experience at a single institution

    Kidney transplantation for end-stage kidney disease is superior to dialysis in terms of quality and quantity of life and cost. Immunosuppressive agents are used to prevent graft failure after kidney transplantation; however, immunosuppression is …

  13. Open Access 28-03-2024 | Online First

    Long-term survival and clinical outcomes of delayed chest closure following lung transplantation

    With recent advances in operative techniques and significant improvement of post-transplant management, lung transplantation (LTx) has become a promising treatment for various pulmonary diseases at their end stage. In low-volume transplant centers …

  14. 25-03-2024 | Myelodysplastic Syndrome | Online First

    Sustained remission after cord blood transplantation for breast cancer with lung metastases and myelodysplastic syndrome

    Allogenic hematopoietic stem cell transplantation (allo-HSCT) is not a standard therapy for solid cancer because of its high toxicity and insufficient evidence levels. However, the potential graft-versus-solid-tumor (GVT) effect of this therapy …

  15. Open Access 08-02-2024 | Bronchoscopy | ReviewPaper

    Airway Complications Related to Lung Transplantation

    According to the United Network for Organ Sharing (UNOS), a record number of lung transplants were performed in the USA in 2022 totaling 2692 [ 1 ]. As the number of lung transplants increases there is a need to enhance the management of …

  16. Open Access 01-12-2024 | OriginalPaper

    Blood MMP-9 measured at 2 years after lung transplantation as a prognostic biomarker of chronic lung allograft dysfunction

    Lung transplantation (LTx) has the potential to bring survival benefits and improve quality of life in selected candidates [ 1 , 2 ]. However, long-term outcomes remain low, with an overall survival of 63% at 5 years post-transplantation [ 3 ]. The …

  17. 05-01-2024 | Online First

    Single lung transplantation using a lung graft from a donor whose contralateral lung is not suitable for lung transplantation

    Single lung transplantation (SLT) is an established treatment for patients with end-stage respiratory failure unless the patients have contraindications for the procedure: infectious lung diseases, significant chylous sputum in …

  18. Open Access 01-12-2024 | OriginalPaper

    Perceptions of barriers to and facilitators of exercise rehabilitation in adults with lung transplantation: a qualitative study in China

    Lung transplantation (LTx) is the sole treatment option for end-stage lung diseases [ 1 , 2 ], and the number of patients on LTx worldwide is steadily increasing [ 3 ]. In China, a total of 1053 LTx cases were recorded in the Lung Transplantation

  19. 01-02-2024 | Septicemia | Online First

    α7nAChR Activation Combined with Endothelial Progenitor Cell Transplantation Attenuates Lung Injury in Diabetic Rats with Sepsis through the NF-κB Pathway

    Chronic diabetes mellitus compromises the vascular system, which causes organ injury, including in the lung. Due to the strong compensatory ability of the lung, patients always exhibit subclinical symptoms. Once sepsis occurs, the degree of lung

  20. 26-12-2023 | OriginalPaper

    Lung Transplantation for Pulmonary Vascular Disease in Children: A United Network for Organ Sharing Analysis

    Pulmonary vascular disease (PVD) represents an important clinical indication for lung transplant (LTx) in infants, children, and adolescents. There is limited information on LTx outcomes in these patients. We explored LTx volumes and post-LTx …

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