Identifying the cause of non-celiac enteropathy can be difficult, with common etiologies including immunodeficiency, infection, medication, and malignancy. Early nutrition support may minimize morbidity.
Ablative radiation therapy can be an alternative option to surgery for the treatment of localized, resectable pancreatic ductal adenocarcinoma, particularly in cases of high surgical risk.
Raised YKL-40 levels are associated with an increased risk for obesity-related and gastrointestinal cancers, particularly liver cancer, in people with type 2 diabetes.
Frontline use of biologic versus conventional synthetic DMARDs for adult-onset Still disease is associated with higher rates of sustained event-free remission.
What can we learn from the similarities and differences between gastric cancer guidelines of different countries, and how might this understanding be used to improve patient care?
Cavernous sinus hemangiomas are rare vascular tumors characterized by significant intraoperative bleeding which makes management extremely difficult. This case reports the 15 year follow up, without neurological compromise, after successful ligation of the left internal carotid artery during resection.
These six cases demonstrate a variety of causes for SAH in the basal cisterns, highlighting the contrasting clinical and imaging features, how to investigate when they are suspected, and significant differences in management.
Geographic atrophy and choroidal or macular neovascularization have previously been seen as separate entities, but the latest evidence supports a high probability of their coexistence.
This case highlights the challenges associated with managing an aggressive macroprolactinoma that's resistant to conventional treatments and explores the use of immunotherapy.
Learn about the rationale for using PARP inhibitors in the neoadjuvant treatment of various cancers with homologous recombination repair deficiency, as well as the ongoing clinical trials and future directions.
Artificial intelligence technologies show substantial potential in predicting treatment responses in rheumatoid arthritis and spondyloarthritis. However, challenges such as methodological variability, data integration, and external validation remain.
Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.
Of the current treatments for lupus nephritis, how many can be classed as disease modifying according to recently proposed criteria? And what are the challenges and considerations for future studies?
Delve into the evolving role of biologics and biosimilars for the treatment of IBD, including adverse effects and the potential of drug delivery systems to address their limitations.
Bone metastases occur in 1–23% of gynecologic cancer patients. What are the available pharmacologic, surgical, and radiation treatments for palliation and the prevention of skeletal-related events in this population?
Childhood obesity is a growing global health concern, but how should obesity be defined and measured in children, and how does it impact health in the short and long term?
Although gastrointestinal adverse events were not uncommon in trials of the novel agent zolbetuximab, they tended to be transient. This is the first report of delayed-onset and persistent gastritis linked to its use.
Blunt thoracic aortic injury in an older person is a critical clinical emergency. Optimal timing and sequence of interventions is crucial in cases co-presenting with pelvic vascular injuries and hemodynamic instability, What is the most appropriate approach?
Upadacitinib once daily, combined with glucocorticoid taper, may be more effective than placebo for inducing sustained remission in patients with giant cell arteritis.
Explore the clinical potential of type 2 diabetes-related PGSs for risk prediction and screening of type 2 diabetes and its comorbidities and risk stratification, with attention to their global applicability.
