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Diabetology Diabetes Therapy

Diabetes Therapy

Open Access Type 2 Diabetes Review

Preventing and treating stroke in type 2 diabetes

The risks of ischemic and hemorrhagic stroke and poor neurological outcomes after stroke are increased in people with type 2 diabetes. Explore how to manage the hyperacute stroke stage and CV disease prevention.

Editor's Choice

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

STEP-HFpEF trial findings indicate that weekly semaglutide improves heart failure symptoms, physical limitations, and body weight in people with obesity-related heart failure and type 2 diabetes.

SGLT2 inhibitors: providing CV, renal, and metabolic protection in type 2 diabetes

Open Access Diabetes Therapy Review

The Improving Diabetes Steering Committee outlines the place, value, and advantages of SGLT2 inhibitors in the treatment of type 2 diabetes. With user-friendly tools to support their use.

Managing type 2 diabetes in children and young people

Open Access Type 2 Diabetes in Children Guideline

This UK consensus guideline provides a practical approach to the assessment and management of type 2 diabetes and associated complications in children and young people.

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Episode 10: Disease-modifying therapy for type 1 diabetes

Reducing the burden of type 1 diabetes

Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.

Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.

Prof. Chantal Mathieu

Case Studies

ICI-induced insulin-dependent diabetes without islet autoantibodies

Diabetes Case Study

Rapidly progressive insulin-dependent diabetes in the absence of islet autoantibodies developed 2 years after starting treatment with the immune checkpoint inhibitor nivolumab.

Nonketotic hyperglycemia hemichorea-hemiballismus

Open Access Type 2 Diabetes Case Study

HC-HB is a rare movement disorder that can occur in patients with poorly controlled diabetes and hyperglycemia without ketoacidosis. The mainstay of treatment is prompt correction of hyperglycemia.

Late onset of immune checkpoint inhibitor-induced type 1 diabetes

Open Access Type 1 Diabetes Case Study

A patient with small-cell lung cancer developed type 1 diabetes many weeks after receiving serplulimab, highlighting the need for continued monitoring of blood glucose levels and early signs and symptoms of diabetes.

Using CGM to optimize type 2 diabetes management with non-intensive insulin treatment in primary care

With the growing importance of primary care in diabetes, this podcast discusses the evidence on continuous glucose monitoring (CGM) use, the role of primary healthcare, and practical tips for interpreting the ambulatory glucose profile (AGP) report. 

Supported by: Abbott Diabetes Care

Prof. Samuel Seidu
Developed by: Adis

Current Reviews

Unexplained Residual Risk In Type 2 Diabetes: How Big Is The Problem?

Type 2 Diabetes Diabetes and Cardiovascular Disease (D Bruemmer, Section Editor)

Type 2 diabetes (T2D) is a major health care problem in the US, affecting approximately 37 million Americans or ~ 10% of the adult population, and for every person with T2D, there ~ 2 individuals with prediabetes [ 1 ]. Cardiovascular disease (CVD) …

Leptin and ghrelin dynamics: unraveling their influence on food intake, energy balance, and the pathophysiology of type 2 diabetes mellitus

Insulins Review article

Type 2 diabetes mellitus (T2DM) is a global health concern, and its prevalence has been steadily increasing over the years [ 1 ]. The International Diabetes Federation (IDF) estimated that approximately 537 million adults (ages 20–79) were living …

AMPK pathway: an emerging target to control diabetes mellitus and its related complications

Diabetes Review article

One of the most common diseases in the modern era, diabetes mellitus (DM), is caused by a variety of factors, including inherited traits and environmental changes [ 1 ]. The prevalence of this chronic metabolic illness is rising as a result of the …

It’s About Timing: Contrasting the Metabolic Effects of Early vs. Late Time-Restricted Eating in Humans

Obesity REVIEW

The high worldwide prevalence of non-communicable metabolic diseases, such as type 2 diabetes (T2D), obesity, hypertension, and dyslipidaemias, persists as a current challenge for public health [ 1 , 2 ]. These diseases remain one of the leading …

Insulins Clinical Trial Summary

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.

Developed by: Springer Medicine

Tweetorials | Vodcasts | Infographics (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)

Stay up to date with the rapidly changing CGM landscape. Learn how to implement and integrate CGM into diabetes management to improve patient care and outcomes.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Vodcasts | Case Scenarios (Link opens in a new window)

Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Webcast | Videos (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)

Discussion-based webcast addressing the causes of clinical inertia in type 2 diabetes.

Supported by:
  • Lilly
Developed by: Springer Healthcare IME
Webinar | 08-11-2023 | 18:00 (CET)

Keynote webinar | Spotlight on diet and diabetes

An expert-led symposium exploring the prevention and management of type 2 diabetes through dietary interventions. Highlights include discussion of the recent EASD guidelines, therapeutic diets, food types and processing, plus psychological factors that influence patient success, and the drivers of healthy eating and diabetes control.

Prof. Mike Lean
Prof. Falko Sniehotta
Developed by: Springer Medicine

Further Reading

Short-term effects of obesity surgery versus low-energy diet on body composition and tissue-specific glucose uptake: a randomised clinical study using whole-body integrated 18F-FDG-PET/MRI

Open Access Insulins Original Research

Over recent decades, the prevalence of obesity has increased dramatically, reaching pandemic levels worldwide, there being over 1.9 billion adults with overweight or obesity in 2016 [ 1 ]. Overweight and obesity are characterised by an excessive …

The IDEAL (Insulin therapy DE-intensificAtion with iglarLixi) Randomised Controlled Trial—Study Design and Protocol

Open Access Insulins Study Protocol

Multiple daily injection insulin regimen (MDI), also referred to as intensive insulin therapy (IIT), represents the most complex type of insulin regimen used in the management of people with type 2 diabetes (PwT2D). Correspondingly, MDI regimen …

Basal Insulinotherapy in Patients Living with Diabetes in France: The EF-BI Study

Open Access Insulins Original Research

Insulin therapy is a necessary step in achieving optimal glycemic targets in type 1 diabetes (T1DM), but also in most advanced patients with type 2 diabetes (T2DM) when oral antidiabetic agents and non-insulin injectable treatments have failed to …

Real-World Effectiveness of the Gla-300 + Cap + App Program in Adult Users Living with Type 2 Diabetes in Taiwan

Open Access Type 2 Diabetes Original Research

The International Diabetes Federation (IDF) Atlas reported that in 2021, 537 million people had diabetes globally; of these, type 2 diabetes is estimated to account for over 90% of cases [ 1 , 2 ]. This number is predicted to increase by 46% to 783 …