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Journal of Cancer Research and Clinical Oncology

Issue 3/2024

Content (62 Articles)

Open Access Sarcoma Review

Primary pulmonary myxoid sarcoma with EWSR1::CREB1 fusion: a literature review

Xinyu Miao, Jing Chen, Lan Yang, Hongyang Lu

Open Access Neuroblastoma Research

Integrated machine learning-driven disulfidptosis profiling: CYFIP1 and EMILIN1 as therapeutic nodes in neuroblastoma

Zhang Mengzhen, Hou Xinwei, Tan Zeheng, Li Nan, Yang Yang, Yang Huirong, Fan Kaisi, Ding Xiaoting, Yang Liucheng, Wu Kai

Open Access Ewing's sarcoma Review

A rare Ewing-like small round cell tumor in prostate: a case report and literature review

Zhen Wang, Jian Ye, Junjie Hu, Nan Zhang, Yichu Yuan

Open Access Sarcoma Research

Clinical outcomes of patients with CIC-rearranged sarcoma: a single institution retrospective analysis

Jacob Murphy, Erin E. Resch, Christopher Leland, Christian F. Meyer, Nicolas J. Llosa, John M. Gross, Christine A. Pratilas

Open Access Research

Evaluation of changes in the clinical benefits of oncology drugs over time following reimbursement using the ASCO-VF and the ESMO-MCBS

Na Ri Yoon, Young Jin Na, Jong Hwan Lee, Inmyung Song, Eui-Kyung Lee, Mi-Hai Park

Open Access Radiotherapy Research

Treatment of poorly differentiated neuroendocrine carcinomas of rectum and anus with chemoradiotherapy: a single-centre evaluation

Louise Elkjær Fløe, Ninna Aggerholm-Pedersen, Elizaveta Mitkina Tabaksblat

Open Access Melanoma Research

Digital decision support for structural improvement of melanoma tumor boards: using standard cases to optimize workflow

David Hoier, Carolin Groß-Ophoff-Müller, Cindy Franklin, Michael Hallek, Esther von Stebut, Thomas Elter, Cornelia Mauch, Nicole Kreuzberg, Philipp Koll

Open Access Research

Transcriptome analysis reveals the clinical significance of CXCL13 in Pan-Gyn tumors

Yue Ding, Quan Zhou, Bo Ding, Yang Zhang, Yang Shen

Open Access Research

Flavokawain C inhibits proliferation and migration of liver cancer cells through FAK/PI3K/AKT signaling pathway

Rong Wang, Rizhao Li, Huibing Yang, Xuejiao Chen, Liangliang Wu, Xiaohui Zheng, Yuepeng Jin

Open Access Trastuzumab Review

Molecular probes targeting HER2 PET/CT and their application in advanced breast cancer

Fang Gao, Fengxu Liu, Jun Wang, Junfang Bi, Luoping Zhai, Dong Li

Open Access Breast Cancer Research

PIK3CA mutation-driven immune signature as a prognostic marker for evaluating the tumor immune microenvironment and therapeutic response in breast cancer

Xueting Ren, Hanxiao Cui, Luyao Dai, Lidan Chang, Dandan Liu, Wenyu Yan, Xuyan Zhao, Huafeng Kang, Xiaobin Ma

Open Access Mantle Cell Lymphoma Research

The influence of marital status at diagnosis on survival of adult patients with mantle cell lymphoma

Ting Zhang, Zhao-tong Wang, Zhuo Li, Shuo-xin Yin, Xun Wang, Hai-zhu Chen

Open Access Adrenocortical Carcinoma Research

A pan-cancer analysis of the oncogenic and immunological roles of transglutaminase 1 (TGM1) in human cancer

Ruicheng Wu, Dengxiong Li, Shuxia Zhang, Jie Wang, Kai Chen, Zhouting Tuo, Akira Miyamoto, Koo Han Yoo, Wuran Wei, Chi Zhang, Dechao Feng, Ping Han

Open Access SCLC Research

Prognostic significance of immunohistochemical classification utilizing biopsy specimens in patients with extensive-disease small-cell lung cancer treated with first-line chemotherapy and immune checkpoint inhibitors

Naoki Shijubou, Toshiyuki Sumi, Terufumi Kubo, Kenta Sasaki, Tomohide Tsukahara, Takayuki Kanaseki, Kenji Murata, Yoshiko Keira, Kotomi Terai, Tatsuru Ikeda, Yuichi Yamada, Hirofumi Chiba, Yoshihiko Hirohashi, Toshihiko Torigoe

Open Access Lung Cancer Research

GATA6 inhibits the biological function of non-small cell lung cancer by modulating glucose metabolism

Weiwei Ju, Lijuan Lin, Qifang Zhang, Xiumei Lv, Shaohui Teng, Yu Hong, Zhixiang Shao, Hanyun Na, Shengjin Yu

Open Access Pancreatic Cancer Research

Unveiling the role of PYGB in pancreatic cancer: a novel diagnostic biomarker and gene therapy target

Li-kun Ren, Ri-shang Lu, Xiao-bin Fei, Shao-jie Chen, Peng Liu, Chang-hao Zhu, Xing Wang, Yao-zhen Pan

Open Access Research

Global analysis of T-cell groups reveals immunological features and common antigen targets of digestive tract tumors

Xiaoxue Li, Yuchao Zhang, Shiwei Guo, Zhenchuan Wu, Hailong Wang, Yi Huang, Yue Wang, Mengni Qiu, Jingyu Lang, Yichuan Xiao, Yufei Zhu, Gang Jin, Landian Hu, Xiangyin Kong

Open Access Review

Psoralen: a narrative review of current and future therapeutic uses

Panagis Galiatsatos, Daniella D. Maydan, Elle Macalpine, Beatrice Schleupner, Alexandra Hunter Aitchison, Andrew D. Lerner, Benjamin Levy, Aditya Halthore, William Eward

Open Access Esophageal Cancer Research

The antagonistic effect of FTO on METTL14 promotes AKT3 m6A demethylation and the progression of esophageal cancer

Ran Wei, Fangfang Zhao, Lingsuo Kong, Youguang Pu, Yuanhai Li, Chunbao Zang

Improved survival over time with immunotherapy in locally advanced and metastatic cutaneous squamous cell carcinomas

Sophie Schneider, Thomas Ferte, Océane Ducharme, Léa Dousset, Sorilla Prey, Caroline Dutriaux, Emilie Gerard, Marie Beylot-Barry, Anne Pham-Ledard

Open Access Soft Tissue Sarcoma Research

A comprehensive analysis of CD47 expression in various histological subtypes of soft tissue sarcoma: exploring novel opportunities for macrophage-directed treatments

Iva Benesova, Linda Capkova, Andrej Ozaniak, Pavel Pacas, Katerina Kopeckova, Dominika Galova, Robert Lischke, Tomas Buchler, Zuzana Ozaniak Strizova

Open Access Bevacizumab Research

PD-(L)1 inhibitors plus bevacizumab and chemotherapy as first-line therapy in PD-L1-negative metastatic lung adenocarcinoma: a real-world data

Yihui Ge, Yujing Zhan, Jie He, Juan Li, Jian Wang, Xiaojuan Wei, Chunni Wang, Aiqin Gao, Yuping Sun

Open Access Spinal Metastasis Research

Synchronous versus metachronous spinal metastasis: a comparative study of survival outcomes following neurosurgical treatment

Mohammed Banat, Anna-Laura Potthoff, Motaz Hamed, Valeri Borger, Jasmin E. Scorzin, Tim Lampmann, Harun Asoglu, Logman Khalafov, Frederic C. Schmeel, Daniel Paech, Alexander Radbruch, Louisa Nitsch, Johannes Weller, Ulrich Herrlinger, Marieta Toma, Gerrit H. Gielen, Hartmut Vatter, Matthias Schneider

Open Access Biomarkers Research

Upregulation of the histone γ-H2AX correlates with worse patient survival and basal-like subtype in pancreatic ductal adenocarcinoma

Karl Knipper, Yussra Hussein, Adrian Georg Simon, Caroline Fretter, Alexander I. Damanakis, Yue Zhao, Christiane J. Bruns, Thomas Schmidt, Felix C. Popp, Alexander Quaas, Su Ir Lyu, Michael Heise, Frank Marusch, Marco Siech, Tawfik Mosa, Bodo Schniewind, Jürgen Tepel, Werner Hartwig, Christoph Prinz, Bettina M. Rau, Marco Niedergethmann, Rainer Kube, George Saada, Wolfgang Hiller, Utz Settmacher

Open Access Artificial Intelligence Review

Large language models as decision aids in neuro-oncology: a review of shared decision-making applications

Aaron Lawson McLean, Yonghui Wu, Anna C. Lawson McLean, Vagelis Hristidis

Open Access Breast Cancer Review

Utilizing large language models in breast cancer management: systematic review

Vera Sorin, Benjamin S. Glicksberg, Yaara Artsi, Yiftach Barash, Eli Konen, Girish N. Nadkarni, Eyal Klang

Open Access Thyroid Cancer Research

Distinguishing benign and malignant thyroid nodules using plasma trimethylamine N-oxide, carnitine, choline and betaine

Liang Shi, Muhong Guo, Cuixiao Shi, Gu Gao, Xianghong Xu, Chuan Zhang, Jingjing Fu, Yudan Ni, Feng Wang, Xue Xue, Fei Yu

Open Access Appendicitis Research

A CT-based radiomics nomogram involving the cystic fluid area for differentiating appendiceal mucinous neoplasms from appendicitis with intraluminal fluid

Xinbin Wang, Na Feng, Yonggang Qiu, Hao Dong, Cuncheng Lou, Junjie Yang, Jieni Yu, Chunyan Jiang, Jianxia Xu, Risheng Yu

Open Access Breast Cancer Research

Predicting pathological complete response to neoadjuvant chemotherapy in breast cancer patients: use of MRI radiomics data from three regions with multiple machine learning algorithms

Guangying Zheng, Jiaxuan Peng, Zhenyu Shu, Hui Jin, Lu Han, Zhongyu Yuan, Xue Qin, Jie Hou, Xiaodong He, Xiangyang Gong

Open Access Neuroblastoma Research

Integrative analysis with machine learning identifies diagnostic and prognostic signatures in neuroblastoma based on differentially DNA methylated enhancers between INSS stage 4 and 4S neuroblastoma

Shan Li, Tao Mi, Liming Jin, Yimeng Liu, Zhaoxia Zhang, Jinkui Wang, Xin Wu, Chunnian Ren, Zhaoying Wang, Xiangpan Kong, Jiayan Liu, Junyi Luo, Dawei He

Open Access Breast Cancer Research

Identification and validation of neutrophils-related subtypes and prognosis model in triple negative breast cancer

Shanqi Li, Yuzhou Qian, Wanchen Xie, Xinyu Li, Jiaying Wei, Long Wang, Guosheng Ren, Xuedong Yin

Open Access Colorectal Cancer Research

The cross talk of ubiquitination and chemotherapy tolerance in colorectal cancer

Ze Rong, Kaifeng Zheng, Jun Chen, Xiaofeng Jin

Open Access Hepatocellular Carcinoma Research

Alteration of serum bile acid profiles of HBV-related hepatocellular carcinoma identified by LC–MS/MS

Sijia Dai, Jingfei Zhu, Xuqiong Chen, Liming Zheng, Xiaoping Li, Longgen Liu

Open Access Hepatitis B Research

Risk of HBV reactivation in HCC patients undergoing combination therapy of PD-1 inhibitors and angiogenesis inhibitors in the antiviral era

Rui Wang, Guili Tan, Dingjia Lei, Yadi Li, JiaoJiao Gong, Yao Tang, Hao Pang, Huating Luo, Bo Qin

Open Access Acute Lymphoblastic Leukemia Research

Chemotherapy-initiated cysteine-rich protein 61 decreases acute B-lymphoblastic leukemia chemosensitivity

Pengchong Shi, Zhen Lin, Yanfang Song, Zhaozhong Li, Menglu Zeng, Li Luo, Yingping Cao, Xianjin Zhu

Open Access Palliative Care Unit Research

Symptom burden and relief in palliative care units of German Comprehensive Cancer Center and other hospitals

Julia Berendt, Sarah Brunner, Maria Heckel, Mitra Tewes, Christoph Ostgathe, Susanne Gahr

Open Access Esophagus Resection Research

Does the time interval from neoadjuvant camrelizumab combined with chemotherapy to surgery affect outcomes for locally advanced esophageal squamous cell carcinoma?

Jiacong Liu, Linhai Zhu, Xuhua Huang, Zhongjie Lu, Yanye Wang, Yuhong Yang, Jiayue Ye, Chen Gu, Wang Lv, Chong Zhang, Jian Hu

Open Access NSCLC Review

BRAF/MEK-targeted therapy in BRAF ex15 p.T599dup mutation-driven NSCLC: a case report

Lan Jiang, Pirong Yang, Yufeng Liu, Juan Li

Open Access Radiotherapy Research

Decision regret of cancer patients after radiotherapy: results from a cross-sectional observational study at a large tertiary cancer center in Germany

Alexander Rühle, Leonie Wieland, Andreas Hinz, Anja Mehnert-Theuerkauf, Nils H. Nicolay, Clemens Seidel

Open Access Glioblastoma Research

Resveratrol ameliorates glioblastoma inflammatory response by reducing NLRP3 inflammasome activation through inhibition of the JAK2/STAT3 pathway

Chao Zhang, Qian Peng, Yuhang Tang, Chengcheng Wang, Shuai Wang, Dong Yu, Shiqiang Hou, Yu Wang, Lanlan Zhang, Ning Lin

Open Access Hematuria Research

Enzyme-labeled liquid-based cytology (ELLBC): a new noninvasive diagnostic method for bladder cancers

Chao Jiang, Xiang Li, Ruilong Chen, Yongliu Yang, Yi Wang

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.