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12667 search results for:

Trastuzumab 

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  1. 01-04-2024 | Trastuzumab | News

    Trastuzumab-emtansine

    Various toxicities
  2. 01-04-2024 | Trastuzumab Emtansine | News

    Trastuzumab emtansine

    Pneumonitis
  3. 01-04-2024 | Trastuzumab | News

    Trastuzumab

    Viral upper respiratory infection
  4. 01-04-2024 | Trastuzumab | News

    Trastuzumab

    Left ventricular ejection fraction decline
  5. 01-04-2024 | Trastuzumab | News

    Trastuzumab

    Sarcoid granulomatous lymphadenitis: case report
  6. 01-04-2024 | Trastuzumab | News

    Trastuzumab-deruxtecan

    Various toxicities
  7. 01-04-2024 | Trastuzumab | News

    Trastuzumab-deruxtecan

    Interstitial lung disease and nausea
  8. 01-04-2024 | Trastuzumab Deruxtecan | News

    Trastuzumab-deruxtecan

    Interstitial lung disease
  9. 01-04-2024 | Trastuzumab | News

    Trastuzumab-deruxtecan

    Lack of efficacy
  10. Open Access 17-02-2024 | Trastuzumab Deruxtecan | OriginalPaper

    Comparison of trastuzumab emtansine, trastuzumab deruxtecan, and disitamab vedotin in a multiresistant HER2-positive breast cancer lung metastasis model

    Human epidermal growth factor 2 (HER2)-positive breast cancer with lung metastases resistant to targeted agents is a common therapeutic challenge. Absence of preclinical lung metastasis models that are resistant to multiple anti-HER2 targeted …

  11. Open Access 01-12-2024 | Trastuzumab | Letter

    A Fab of trastuzumab to treat HER2 overexpressing breast cancer brain metastases

    Despite major therapeutic advances for two decades, including the most recently approved anti-HER2 drugs, brain metastatic localizations remain the major cause of death for women with metastatic HER2 breast cancer. The main reason is the limited …

  12. Open Access 02-05-2024 | Trastuzumab | Online First

    Role of Early Left Atrial Functional Decline in Predicting Cardiotoxicity in HER2 Positive Breast Cancer Patients Treated With Trastuzumab

    Trastuzumab is widely used in HER2 breast cancer. However, it may cause left ventricular (LV) dysfunction. A decrease in LV global longitudinal strain (GLS) has been previously demonstrated to be a good predictor of subsequent cancer therapy …

  13. 01-03-2024 | Sarcoidosis | News

    Trastuzumab

    Sarcoidosis
  14. 01-03-2024 | Trastuzumab | News

    Trastuzumab-deruxtecan

    Neutropenia
  15. 01-03-2024 | Trastuzumab | News

    Trastuzumab/trastuzumab-deruxtecan

    Interstitial lung disease and lack of efficacy
  16. 02-04-2024 | Trastuzumab | OriginalPaper

    A Phase I Clinical Study Comparing the Pharmacokinetics, Safety, and Immunogenicity of GB221 Injection and Trastuzumab (Herceptin®) in Healthy Chinese Adults

    Breast cancer is the most commonly diagnosed cancer and the primary cause of cancer-related death among women [ 1 ]. About 20% of breast cancer patients overexpress human epidermal growth factor receptor 2 (HER2), and the over-expression of HER2 is …

  17. Open Access 01-12-2024 | Trastuzumab | OriginalPaper

    Trastuzumab in patients with breast cancer and pre-existing left ventricular systolic dysfunction

    Cancer remains a significant global health challenge and a leading cause of mortality, with GLOBOCAN 2020 reporting 19.3 million new cases and nearly 10 million deaths in 2020 alone. Among these, breast cancer emerges as the most frequently …

  18. Open Access 01-12-2024 | Neratinib | OriginalPaper

    NSABP FB-10: a phase Ib/II trial evaluating ado-trastuzumab emtansine (T-DM1) with neratinib in women with metastatic HER2-positive breast cancer

    In 2013, T-DM1 was the first HER2-targeted antibody–drug conjugate (ADC) granted FDA-approval for late-stage metastatic breast cancer after prior trastuzumab. In 2019, T-DM1 was approved as post-neoadjuvant therapy in patients with residual …

  19. Open Access 08-04-2024 | Trastuzumab | Online First

    Exploratory analysis of serum HER2 extracellular domain for HER2 positive gastric cancer treated with SOX plus trastuzumab

    Human epidermal growth factor 2 (HER2) is one of the famous oncogenes in breast and gastric cancer [ 1 ]. HER2 overexpression or its gene amplification have been reported up to 20% in gastric cancer [ 2 – 4 ], suggesting that it is a critical …

  20. 01-04-2024 | Trastuzumab | Online First

    Rechallenge of Trastuzumab-based Therapy in HER2-Positive Breast Cancer Patients who Progressed Under TDM-1

    Data on rechallenges of HER2 targetted agents in breast cancer patients is limited. The goal of the study was to evaluate the effectiveness of trastuzumab-based therapy in patients who progressed under trastuzumab emtansine (TDM-1). The study was …

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