Issue 5/2024
Content (37 Articles)
Design and evaluation of a multiepitope vaccine for pancreatic cancer using immune-dominant epitopes derived from the signature proteome in expression datasets
Sooram Banesh, Nupoor Patil, Vihadhar Reddy Chethireddy, Arnav Bhukmaria, Prakash Saudagar
The efficacy and safety of PD-1 inhibitor combined with TACE in the first-line treatment of unresectable hepatocellular carcinoma
Qing-Qing Liu, Xiang-Xu Wang, Hongchen Ji, Qiong-Yi Dou, Hong-Mei Zhang
Estrogen-receptor status determines differential regulation of α1- and α2-adrenoceptor-mediated cell survival, angiogenesis, and intracellular signaling responses in breast cancer cell lines
Hannah P. Priyanka, Uday P. Pratap, Rahul S. Nair, Ramasamy Vasantharekha, Srinivasan ThyagaRajan
Investigation of cellular communication and signaling pathways in tumor microenvironment for high TP53-expressing osteosarcoma cells through single-cell RNA sequencing
Kai Xiong, Yuqi Fang, Boyuan Qiu, Chaotao Chen, Nanchang Huang, Feiyuan Liang, Chuangming Huang, Tiantian Lu, Li Zheng, Jinmin Zhao, Bo Zhu
Regulation of cancer progression by CK2: an emerging therapeutic target
Shakeel Hussain, Yilei Guo, Yu Huo, Juanjuan Shi, Yongzhong Hou
Physical characterization and bioavailability assessment of 5-fluorouracil-based nanostructured lipid carrier (NLC): In vitro drug release, Hemolysis, and permeability modulation
Mainuddin, Anoop Kumar, Ratneshwar Kumar Ratnesh, Jay Singh, Shweta Dumoga, Nitin Sharma, Amulya Jindal
Bioinformatics-based screening and analysis of the key genes involved in the influence of antiangiogenesis on myeloid-derived suppressor cells and their effects on the immune microenvironment
XiangFei Zhao, RuGang Zhao, JuYi Wen, Xia Zhang, ShanShan Wu, Juan Fang, JunPeng Ma, LiPin Gao, Yi Hu
Exploring the combined anti-cancer effects of sodium butyrate and celastrol in glioblastoma cell lines: a novel therapeutic approach
Bahar Kartal, Farika Nur Denizler-Ebiri, Mustafa Güven, Filiz Taşpınar, Hande Canpınar, Sedat Çetin, Tuğçe Karaduman, Serkan Küççüktürk, Javier Castresana, Mehmet Taşpınar
Potential role of immune cell therapy in gynecological cancer and future promises: a comprehensive review
Sandipan Dasgupta, Sakuntala Gayen, Tania Chakraborty, Naureen Afrose, Ranita Pal, Sutapa Mahata, Vilas Nasare, Souvik Roy
Effect of capecitabine as monotherapy for HER2 normal metastatic breast cancer
Anne-Dorthe Mosgaard Knudsen, Mikala Wej Modvig, Marianne Vogsen, Annette Raskov Kodahl
YWHAG promotes colorectal cancer progression by regulating the CTTN-Wnt/β-catenin signaling axis
Yuanben Wang, Yulin Cao, Ying Chen, Han Cheng, Zhiang Liu, Mengna Wang, Yuyang Feng, Bojian Fei, Kaisa Cui, Zhaohui Huang
Structure-based multitargeted docking screening, pharmacokinetics, DFT, and dynamics simulation studies reveal mitoglitazone as a potent inhibitor of cellular survival and stress response proteins of lung cancer
Abdulkarim S. Binshaya, Omar Saad Alkahtani, Fahad M. Aldakheel, Ahmed Hjazi, Hassan H. Almasoudi
Investigating the correlation between prominent viruses and hematological malignancies: a literature review
Arian Haghtalab, Milad Hejazi, Naeem Goharnia, Ali Yekanlou, Kousha Hazhir, Asma Barghi, Zahra Bazzaz, Iman Allahverdizadeh, Ataollah GhalibafSabbaghi
Regulation of hippo signaling mediated apoptosis by Rauvolfia tetraphylla in triple-negative breast cancer
B. Balavaishnavi, M. Kamaraj, T. G. Nithya, P. Santhosh, S. GokilaLakshmi, Mohammed Rafi Shaik
Unlocking the potential: phenylboronic acid as a nuclear-targeting boron agent for neutron capture therapy
Jiejian Chen, Yonghao Li, Xiaoning Gan, Chengyin Weng, Xisheng Fang, Guolong Liu
Citalopram, an antipsychotic agent, induces G1/G0 phase cell cycle arrest and promotes apoptosis in human laryngeal carcinoma HEP-2 cells
Mohammed Salama, Abeer Ali, Fawziya A. R. Ibrahim, Seham Elabd
Probiotic-derived silver nanoparticles target mTOR/MMP-9/BCL-2/dependent AMPK activation for hepatic cancer treatment
Alaa Elmetwalli, Mohamed O. Abdel-Monem, Ali H. El-Far, Gehad S. Ghaith, Noaf Abdullah N. Albalawi, Jihan Hassan, Nadia F. Ismail, Tarek El-Sewedy, Mashael Mashal Alnamshan, Nouf K. ALaqeel, Ibtesam S. Al-Dhuayan, Mervat G. Hassan
Immunomodulatory effects of Diospyros peregrina fruit preparation (DFP) in non-small cell lung cancer (NSCLC) by utilizing dendritic cell-mediated antigen presentation and T helper (TH) cell differentiation
Nawaneetan Sriraman, Ankita Sarkar, Sohom Naskar, Nitika Mahajan, Oishi Mukherjee, R. Pradeep, Melvin George, Koustav Sarkar
Increased V-ATPase activity can lead to chemo-resistance in oral squamous cell carcinoma via autophagy induction: new insights
Ahmadreza Lagzian, Marziye Askari, Melika Sadat Haeri, Nastaran Sheikhi, Sara Banihashemi, Mohsen Nabi-Afjadi, Yalda Malekzadegan
Study of the effect of sFRP1 protein on molecules involved in the regulation of DNA methylation in CML cell line
Nazli Demirkiran, Bengusu Aydin, Melek Pehlivan, Zeynep Yuce, H. Ogun Sercan
Combination of IFN-gamma with STING agonist and PD-1 immune checkpoint blockade: a potential immunotherapy for gastric cancer
Shahnaz Hosseinzadeh, Mahsa Imani, Farhad Pourfarzi, Narjes Jafari, Saeid AbedianKenari, Elham Safarzadeh
Coadministration of doxorubicin with vitamin D3, Lactobacillus acidophilus, and Lactobacillus casei in the 4T1 mouse model of breast cancer: anticancer and enteroprotective effects
Mohammad Ali Mirzadeh, Majid Eslami, Ali Ghanbari, Sam Zarbakhsh, Sedighe Yosefi, Abbas Pakdel
Recent developments in targeting breast cancer stem cells (BCSCs): a descriptive review of therapeutic strategies and emerging therapies
Khubaib Ali, Muhammad Nabeel, Fatima Mohsin, Mehwish Iqtedar, Muhammad Islam, Muhammad Fawad Rasool, Furqan K. Hashmi, Syed Ahmed Hussain, Hamid Saeed
A novel α,β-unsaturated ketone inhibits leukemia cell growth as PARP1 inhibitor
Weijia Zhao, Min Mo, Jia Yu, Sha Cheng, Guiping Long, Zhiqiong Luo, Wei Liang, Chen Yan, Heng Luo, Baofei Sun
Dual function of activated PPARγ by ligands on tumor growth and immunotherapy
Mingjun Chen, Huijie Wang, Qian Cui, Juanjuan Shi, Yongzhong Hou
Exploring the immunomodulatory potential of Brahmi (Bacopa monnieri) in the treatment of invasive ductal carcinoma
Sohini Roy, Geetha Shanmugam, Sudeshna Rakshit, R. Pradeep, Melvin George, Koustav Sarkar
Liver cancer wars: plant-derived polyphenols strike back
Chengu Niu, Jing Zhang, Patrick I. Okolo 3rd
Chlordiazepoxide against signalling, receptor and regulatory proteins of breast cancer: a structure-based in-silico approach
Ahad Amer Alsaiari, Amal F. Gharib, Maha Mahfouz Bakhuraysah, Amani A. Alrehaili, Shatha M. Algethami, Hayfa Ali Alsaif, Norah Al Harthi, Mohammed Ageeli Hakami
Identification of small molecule inhibitors against Lin28/let-7 to suppress tumor progression and its alleviation role in LIN28-dependent glucose metabolism
Rachanaa Raja, Rajamanikandan Sundararaj, Ruckmani Kandasamy
The role of SWI/SNF complexes in digestive system neoplasms
Hanyun Liang, Xin Zheng, Xiao Zhang, Yan Zhang, Jie Zheng
FTO promotes gastric cancer progression by modulating MAP4K4 expression via demethylation in an m6A-dependent manner
Zhe Yin, Xiong Guo, Xiaolong Liang, Ziwei Wang
Correction to: Gingerol and/or sorafenib attenuates the DAB-induced HCC and hepatic portal vein dilatation via ATG4/CASP3 and COIIV/COX-2/NF-κB expression
Afrah Fatthi Salama, Ali H. El-Far, Esraa Ali Anbar, Sabry Ali El-Naggar, Rami M. Elshazli, Alaa Elmetwalli
Comprehensive review of the repositioning of non-oncologic drugs for cancer immunotherapy
Abdur Rauf, Payal B. Joshi, Ahmed Olatunde, Nabia Hafeez, Zubair Ahmad, Hassan A. Hemeg, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Muthu Thiruvengadam, Dhivya Viswanathan, Govindasamy Rajakumar, Rekha Thiruvengadam
N-methyl-D-aspartate receptors and thymoquinone induce apoptosis and alteration in mitochondria in colorectal cancer cells
Ferhat Sirinyildiz, Simge Unay
Ferroptosis is an effective strategy for cancer therapy
Afrasyab Khan, Yu Huo, Yilei Guo, Juanjuan Shi, Yongzhong Hou
Anti-cancer potential of zerumbone in cancer and glioma: current trends and future perspectives
Alborz Soroush, Siavash Pourhossein, Dorrin Hosseingholizadeh, Ahmed Hjazi, Reza Shahhosseini, Haniyeh Kavoosi, Nazgol Kermanshahi, Parisa Behnamrad, Nima Ghavamikia, Mehdi Dadashpour, Sepideh Karkon Shayan
Challenges and strategies in relation to effective CAR-T cell immunotherapy for solid tumors
Guangxun Yuan, Mengke Ye, Yixi Zhang, Xun Zeng