Issue 10/2023
Content (29 Articles)
Metformin as a promising target for DPP4 expression: computational modeling and experimental validation
Amr Ahmed El-Arabey, Haiyan Zhang, Mohnad Abdalla, Samia T. Al-Shouli, Samia S. Alkhalil, Yi Liu
Chrysin and chrysin-loaded nanocarriers induced immunogenic cell death on B16 melanoma cells
Yasaman Oliyapour, Sheida Dabiri, Ommoleila Molavi, Mohammad Saeid Hejazi, Soodabeh Davaran, Sevda Jafari, Soheila Montazersaheb
In vitro siRNA-mediated GPX4 and AKT1 silencing in oxaliplatin resistance cancer cells induces ferroptosis and apoptosis
Morteza Golbashirzadeh, Hamid Reza Heidari, Ali Asghar Aghamolayi, Yasin Fattahi, Mehdi Talebi, Ahmad Yari Khosroushahi
EZH2 inhibitor Tazemetostat synergizes with JQ-1 in esophageal cancer by inhibiting c-Myc signaling pathway
Nan Ding, Abin You, Senxia Zhao, Hu Yang, Chunping Lai, Feng Ye
Reverse vaccinology and immunoinformatics approaches to design multi-epitope based vaccine against oncogenic KRAS
Prasanna Srinivasan Ramalingam, Sivakumar Arumugam
Targeting MerTK decreases efferocytosis and increases anti-tumor immune infiltrate in prostate cancer
Kayla V. Myers Chen, Amber E. de Groot, Sabrina A. Mendez, Mikaela M. Mallin, Sarah R. Amend, Kenneth J. Pienta
Single-cell RNA sequencing reveals the effects of anti-PD-L1 therapy on 3LL lung cancer model and its tumor microenvironment
Hongyu Zhang, Hao Huang, Shaoxian Wu, Xian He, Junjun Chen, Xiao Zheng, Lujun Chen, Zhigang Wang
The NEDD8-activating enzyme E1 UBA3 orchestrates the immunosuppressive microenvironment in lung adenocarcinoma via the NF-кB pathway
Xiongzhi Lin, Shuhan Yang, Caichuan Zhou, Chengcheng Ao, Dongsheng Sun
Knockdown of SIX4 inhibits pancreatic cancer cells via apoptosis induction
Mohammad Heiat, Ehsan Rezaei, Javad Gharechahi, Masoumeh Abbasi, Javad Behroozi, Mohammad Ali Abyazi, Behzad Baradaran
RIG-I promotes cell proliferation in esophageal squamous cell carcinoma by facilitating p21 degradation
Meng Wang, Yangyang Zhang, Liping Gao, Hailin Zhang, Zhenwei Yang, Jialong Liu, Wenqing Shan, Lingxiu Zeng, Ranran Zhang, Yong Li, Jing Liu
The apoptotic effect of the Lycopodium clavatum extracts on MCF-7 human breast cancer cells
Yusuf Kucukbagriacik, Mohammadreza Dastouri, Humeyra Yilmaz, Evrim Gunes Altuntas
RNF149 confers cisplatin resistance in esophageal squamous cell carcinoma via destabilization of PHLPP2 and activating PI3K/AKT signalling
Jinrong Zhu, Jiuren Tang, Yongqi Wu, Xiangyu Qiu, Xin Jin, Rongxin Zhang
GLDC promotes colorectal cancer metastasis through epithelial–mesenchymal transition mediated by Hippo signaling pathway
Hao Yu, Xueqing Hu, Yingru Zhang, Jiajia Wang, Zhongya Ni, Yan Wang, Huirong Zhu
Chitosan oligosaccharide suppresses osteosarcoma malignancy by inhibiting CEMIP via the PI3K/AKT/mTOR pathway
IlJin Sim, WonGyom Choe, JinJu Ri, Hang Su, Safwat Adel Abdo Moqbel, WeiQi Yan
Identification of the therapeutic mechanism of the saffron crocus on glioma through network pharmacology and bioinformatics analysis
Xiaobing Yang, Dulegeqi Man, Peng Zhao, Xingang Li
Vitamin C inhibits the growth of colorectal cancer cell HCT116 and reverses the glucose-induced oncogenic effect by downregulating the Warburg effect
Chang Yu, Su Min, Feng Lv, Li Ren, You Yang, Lihao Chen
Label-free nLC-MS/MS proteomic analysis reveals significant differences in the proteome between colorectal cancer tissues and normal colon mucosa
Sezgin Zeren, Semih Seker, Gizem Akkaş Akgün, Emrah Okur, Azmi Yerlikaya
AKT-independent signaling in PIK3CA-mutant thyroid cancer mediates resistance to dual SRC and MEK1/2 inhibition
Madison M. Rose, Kelsey W. Nassar, Vibha Sharma, Rebecca E. Schweppe
Effect of insulin on IR and GLP1-R expressions in HT22 cells
Melek Tunc-Ata, Zeynep Mine Altunay, Aysel Alphan, Vural Kucukatay
Expanding CYLD protein in NF-κβ/TNF-α signaling pathway in response to Lactobacillus acidophilus in non-metastatic rectal cancer patients
Farhad Zamani, Solmaz Khalighfard, Mohammad Reza Kalhori, Amirhoushang Poorkhani, Taghi Amiriani, Payam Hosseinzadeh, Ebrahim Esmati, Mahdi Alemrajabi, Alireza Nikoofar, Fahimeh Safarnezhad Tameshkel, Ali Mohammad Alizadeh
RETRACTED ARTICLE: Silencing POLE2 promotes apoptosis and inhibits proliferation of oral squamous cell carcinomas by inhibiting PI3K/AKT signaling pathway
Shengyou Ge, Kexin Wang, Yuxiang Meng, Zongxuan He, Xiaochen Yang, Wei Shang, Lin Wang
Single-cell transcriptomic analysis reveals crucial oncogenic signatures and its associative cell types involved in gastric cancer
Karthik Sekaran, Rinku Polachirakkal Varghese, Hatem Zayed, Achraf El Allali, C. George Priya Doss
Role of plectin and its interacting molecules in cancer
Keyu Gao, Zhimin Gao, Mingyi Xia, Hailong Li, Jiehui Di
Novel insights on perils and promises of miRNA in understanding colon cancer metastasis and progression
Lubna Tariq, Azher Arafah, Nouroz Sehar, Aarif Ali, Andleeb Khan, Iyman Rasool, Shahzada Mudasir Rashid, Sheikh Bilal Ahmad, Saba Beigh, Tanveer Ul Hassan Dar, Muneeb U. Rehman
Therapeutic approaches for HTLV-1-associated adult T-cell leukemia/lymphoma: a comprehensive review
Arash Letafati, Roben Soheili, Mehdi Norouzi, Parastoo Soleimani, Sayed-Hamidreza Mozhgani
Role of tissue markers associated with tumor microenvironment in the progression and immune suppression of oral squamous cell carcinoma
Suganya Ramalingam, Sivaramakrishnan Shantha, Susruthan Muralitharan, Uma Sudhakar, Harikrishnan Thamizhchelvan, Venkatachalam Deepa Parvathi
The role of polyploidy in tumorigenesis: confusion versus reality
Jinsong Liu