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Hepatology International

Issue 5/2022

Content (29 Articles)

Open Access Filgrastim Editorial

G-CSF treatment in decompensated liver disease: a double-edged sword?

Cornelius Engelmann, Thomas Berg

Management of spontaneous portosystemic shunts at the time of liver transplantation: treatment or observation? Results of a systematic review

Caterina Cusumano, Stefano Gussago, Martina Guerra, Chloe Paul, François Faitot, Philippe Bachellier, Pietro Addeo

Liver transplantation in patients with acute-on-chronic liver failure

Gandhi Lanke, Joseph J. Alukal, Paul J. Thuluvath

Care Point-of-View

MAFLD, patient-centred care, and APASL

Shiv K. Sarin, Mohammed Eslam, Jian-Gao Fan, Han-Chieh Lin, Jacob George, Masao Omata

Fatty Liver Original Article

Non-invasive evaluation of NAFLD and the contribution of genes: an MRI-PDFF-based cross-sectional study

Aruhan Yang, Xiaoxue Zhu, Lei Zhang, Yingwen Zhang, Dezhi Zhang, Meishan Jin, Junqi Niu, Huimao Zhang, Yanhua Ding, Guoyue Lv

Liver Transplantation Original Article

Systematic review and meta-analysis: impact of anti-viral therapy on portal hypertensive complications in HBV patients with advanced chronic liver disease

Yuanyuan Kong, Tingting Lv, Min Li, Lianghui Zhao, Tongtong Meng, Shanshan Wu, Wei Wei, Qian Zhang, Sha Chen, Hong You, Sabela Lens, Hitoshi Yoshiji, Sven Francque, Emmanouil Tsochatzis, Shiv K. Sarin, Mattias Mandorfer, Jidong Jia

Fatty Liver Original Article

The regulation effect of GLUT9/SLC2A9 on intrahepatic uric acid level and metabolic associated fatty liver disease

Hang Zeng, Chenxi Tang, Bingru Lin, Mengli Yu, Xinyu Wang, Jinghua Wang, Shenghui Chen, Chaohui Yu

Computed Tomography Original Article

CT-based visual grading system for assessment of hepatic steatosis: diagnostic performance and interobserver agreement

Hyo Jung Park, Kyoung Won Kim, Heon-Ju Kwon, Sunyoung Lee, Dong Wook Kim, Hye Hyeon Moon, Gi-Won Song, Sung-Gyu Lee

Sarcopenia Original Article

Low skeletal muscle mass is associated with more severe histological features of non-alcoholic fatty liver disease in male

Xiao-Yan Pan, Wen-Yue Liu, Pei-Wu Zhu, Gang Li, Liang-Jie Tang, Feng Gao, Ou-Yang Huang, Hai-Yang Yuan, Giovanni Targher, Christopher D. Byrne, Xiao-Dong Wang, Ming-Hua Zheng

Open Access Liver Transplantation Original Article

Epidemiology and outcomes of primary sclerosing cholangitis: an Australian multicentre retrospective cohort study

Natassia Tan, N. Ngu, T. Worland, T. Lee, T. Abrahams, K. Pandya, E. Freeman, N. Hannah, K. Gazelakis, R. G. Madden, K. D. Lynch, Z. Valaydon, S. Sood, A. Dev, S. Bell, A. Thompson, J. Ding, A. J. Nicoll, K. Liu, P. Gow, J. Lubel, W. Kemp, S. K. Roberts, A. Majeed

Hypertension Original Article

ABC: a novel algorithm to stratify decompensation risk in patients with compensated advanced chronic liver disease (CHESS2108): an international, multicenter cohort study

Chuan Liu, Jia Li, Yu Jun Wong, Qing Xie, Masashi Hirooka, Hirayuki Enomoto, Tae Hyung Kim, Amr Shaaban Hanafy, Ruiling He, Yohei Koizumi, Yoichi Hiasa, Takashi Nishimura, Hiroko Iijima, Young Kul Jung, Hyung Joon Yim, Jianzhong Ma, Qing-Lei Zeng, Shiv Kumar Sarin, Xiaolong Qi

Acute Liver Failure Original Article

Low platelets: a new and simple prognostic marker for patients with hepatitis E virus-related acute liver failure

Xiuying Mu, Jun Zou, Jing Chen, Jingjing Tong, Lian Ma, Peng Ning, Huajie Li, Zhiqian Feng, Tao Yang, Kai Liu, Wen-Jing Cao, Ming-Ju Zhou, Chao Zhang, Ji-Yuan Zhang, Yan-Mei Jiao, Jin-Wen Song, Xing Fan, Ming Shi, Jinhua Hu, Ruonan Xu, Fu-Sheng Wang

Hepatic Encephalopathy Original Article

Multiple cycles of granulocyte colony-stimulating factor in decompensated cirrhosis: a double-blind RCT

Aswath Venkitaraman, Arka De, Nipun Verma, Sunita Kumari, Bidyalaxmi Leishangthem, Ratti Ram Sharma, Naveen Kalra, Sandeep Grover, Virendra Singh

Epstein-Barr Virus Original Article

The immune microenvironment features and response to immunotherapy in EBV-associated lymphoepithelioma-like cholangiocarcinoma

Nai-Jung Chiang, Ya-Chin Hou, Kien Thiam Tan, Hung-Wen Tsai, Yih-Jyh Lin, Yi-Chen Yeh, Li-Tzong Chen, Ya-Fu Hou, Ming-Huang Chen, Yan-Shen Shan

Prognostic impact of C-reactive protein and alpha-fetoprotein in immunotherapy score in hepatocellular carcinoma patients treated with atezolizumab plus bevacizumab: a multicenter retrospective study

Takeshi Hatanaka, Satoru Kakizaki, Atsushi Hiraoka, Toshifumi Tada, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi, Shinya Fukunishi, Kunihiko Tsuji, Toru Ishikawa, Kazuto Tajiri, Hironori Ochi, Satoshi Yasuda, Hidenori Toyoda, Chikara Ogawa, Takashi Nishimura, Noritomo Shimada, Kazuhito Kawata, Hisashi Kosaka, Takaaki Tanaka, Hideko Ohama, Kazuhiro Nouso, Asahiro Morishita, Akemi Tsutsui, Takuya Nagano, Norio Itokawa, Tomomi Okubo, Taeang Arai, Michitaka Imai, Atsushi Naganuma, Yohei Koizumi, Shinichiro Nakamura, Kouji Joko, Masaki Kaibori, Hiroko Iijima, Yoichi Hiasa, Takashi Kumada

Hepatitis B Original Article

Liver cancer and hepatic decompensation events in patients hospitalized with viral hepatitis in Spain

José-Manuel Ramos-Rincon, Héctor Pinargote-Celorio, Carmen de Mendoza, Clara Ramos-Belinchón, Pablo Barreiro, Ana Treviño, Octavio Corral, Vicente Soriano

Open Access Systemic Therapy Original Article

Lenvatinib for the treatment of hepatocellular carcinoma—a real-world multicenter Australian cohort study

Kurvi Patwala, David Stephen Prince, Yael Celermajer, Waafiqa Alam, Eldho Paul, Simone Irene Strasser, Geoffrey William McCaughan, Paul Gow, Siddharth Sood, Elise Murphy, Stuart Roberts, Elliot Freeman, Elizabeth Stratton, Scott Anthony Davison, Miriam Tania Levy, McCawley Clark-Dickson, Vi Nguyen, Sally Bell, Amanda Nicoll, Ashley Bloom, Alice Unah Lee, Marno Ryan, Jessica Howell, Zina Valaydon, Alexandra Mack, Ken Liu, Anouk Dev

Open Access Hepatocellular Carcinoma Original Article

Combining stereotactic body radiotherapy with camrelizumab for unresectable hepatocellular carcinoma: a single-arm trial

Jian-Xu Li, Ting-Shi Su, Wen-Feng Gong, Jian-Hong Zhong, Liu-Ying Yan, Jie Zhang, Li-Qing Li, Mei-Ling He, Rui-Jun Zhang, You-Qin Du, Xiao-Ting Wang, Shi-Xiong Liang, Bang-De Xiang

Liver Resection Original Article

A deep learning model with incorporation of microvascular invasion area as a factor in predicting prognosis of hepatocellular carcinoma after R0 hepatectomy

Kang Wang, Yanjun Xiang, Jiangpeng Yan, Yuyao Zhu, Hanbo Chen, Hongming Yu, Yuqiang Cheng, Xiu Li, Wei Dong, Yan Ji, Jingjing Li, Dong Xie, Wan Yee Lau, Jianhua Yao, Shuqun Cheng

Systemic Therapy Original Article

Prognosis and treatment pattern of advanced hepatocellular carcinoma after failure of first-line atezolizumab and bevacizumab treatment

Ching-Tso Chen, Yin-Hsun Feng, Chia-Jui Yen, San-Chi Chen, Yun-Tzu Lin, Li-Chun Lu, Chih-Hung Hsu, Ann-Lii Cheng, Yu-Yun Shao

Open Access Hepatitis B Original Article

Heat-shock protein 90α is a potential prognostic and predictive biomarker in hepatocellular carcinoma: a large-scale and multicenter study

Ke Su, Yanlin Liu, Pan Wang, Kun He, Fei Wang, Hao Chi, Mingyue Rao, Xueting Li, Lianbin Wen, Yanqiong Song, Jianwen Zhang, Tao Gu, Ke Xu, Qi Li, Jiali Chen, Zhenying Wu, Han Li, Weihong Huang, Lan Chen, Jian Tong, Hongyan Li, Xunjie Feng, Siyu Chen, Binbin Yang, Hongping Jin, Yue Yang, Hanlin Liu, Chao Yang, Ming Wu, Fangyu Xiong, Keyi Peng, Lechuan Zhu, Yaoyang Xu, Xue Tang, Zunyuan Tan, Xiaotong Luo, Hanyue Zheng, Yuxin Zhang, Lu Guo, Yunwei Han

A somatic mutation-derived LncRNA signatures of genomic instability predicts the prognosis and tumor microenvironment immune characters in hepatocellular carcinoma

Chuan Jin, Jian-Sen Zhao, Xu-Qi Huang, Xian-Zi Yang, Fei-Yu Niu, Jin-Rong Lin, Lei Ma, Yan-Xia Shi, Xiao-Shan Li, Peng Jiang, Sha Gao, Feng Li, Ye Song

Hepatitis Original Article

Acute variceal bleeding portends poor outcomes in patients with acute-on-chronic liver failure: a propensity score matched study from the APASL ACLF Research Consortium (AARC)

Sanchit Sharma, Samagra Agarwal, Anoop Saraya, Ashok Choudhury, Mamun Al Mahtab, Mohd. Shahinul Alam, Sanjiv Saigal, Dong Joon Kim, C. E. Eapen, Ashish Goel, Qin Ning, Harshad Devarbhavi, Virendra Singh, Akash Shukla, Saeed Hamid, Jinhua Hu, Soek-Siam Tan, Anil Arora, Manoj Kumar Sahu, Mohd. Rela, Dinesh Jothimani, P. N. Rao, Anand Kulkarni, Hashmik Ghaznian, Guan Huei Lee, Duan Zhongping, Ajit Sood, Omesh Goyal, Laurentius A. Lesmana, Rinaldi C. Lesmana, Sombat Treeprasertsuk, Nan Yuemin, Samir Shah, Han Tao, V. M. Dayal, Xin Shaojie, Fazal Karim, Zaigham Abbas, Jose D. Sollano, Kemal Fariz Kalista, Ananta Shreshtha, Diana Payawal, Masao Omata, Shiv Kumar Sarin, Shiv Kumar Sarin, Ashok Choudhury, Manoj K. Sharma, Rakhi Maiwall, Mamun Al Mahtab, Salimur Rahman, Sanjiv Saigal, Neeraj Saraf, A. S. Soin, Harshad Devarbhavi, Dong Joon Kim, R. K. Dhiman, Ajay Duseja, Sunil Taneja, C. E. Eapen, Ashish Goel, Q. Ning, Tao Chen, Ke Ma, Z. Duan, Chen Yu, Sombat Treeprasertsuk, S. S. Hamid, Amna S. Butt, Wasim Jafri, Akash Shukla, Vivek Saraswat, Soek Siam Tan, Ajit Sood, Vandana Midha, Omesh Goyal, Hasmik Ghazinyan, Anil Arora, Jinhua Hu, Manoj Sahu, P. N. Rao, Guan H. Lee, Seng G. Lim, Laurentius A. Lesmana, Cosmas Rinaldi Lesmana, Samir Shah, V. G. Mohan Prasad, Diana A. Payawal, Zaigham Abbas, A. Kadir Dokmeci, Jose D. Sollano, Gian Carpio, Ananta Shresta, G. K. Lau, Md.Fazal Karim, Gamal Shiha, Rino Gani, Kemal Fariz Fariz Kalista, Man-Fung Yuen, Seema Alam, Rajeev Khanna, Vikrant Sood, Bikrant Bihari Lal, Viniyendra Pamecha, Ankur Jindal, V. Rajan, Vinod Arora, Osamu Yokosuka, Madunil A. Niriella, Hai Li, Xiaolong Qi, Atsushi Tanaka, Satoshi Mochida, Dominic Ray Chaudhuri, Ed Gane, Khin Maung Win, Wei Ting Chen, Mohd Rela, Dharmesh Kapoor, Amit Rastogi, Pratibha Kale, Archana Rastogi, Chhagan Bihari Sharma, Meenu Bajpai, Virender Singh, Madhumita Premkumar, Sudhir Sudhir, A. Olithselvan, Cyriac Abby Philips, Anshu Srivastava, Surender K. Yachha, Zeeshan Ahmad Wani, B. R. Thapa, Anoop Saraya, Shalimar, Ashish Kumar, Manav Wadhawan, Subash Gupta, Kaushal Madan, Puja Sakhuja, Vivek Vij, Barjesh C. Sharma, Hitendra Garg, Vishal Garg, Chetan Kalal, Lovkesh Anand, Tanmay Vyas, Rajan P. Mathur, Guresh Kumar, Priyanka Jain, Samba Siva Rao Pasupuleti, Yogesh K. Chawla, Abhijit Chowdhury, Shahinul Alam, Do Seon Song, Jin Mo Yang

Statins Letter to the Editor

Aspirin for patients after TIPS: an old dog with new tricks?

Jitao Wang, Dengxiang Liu, Shubo Chen, Xiaolong Qi

Open Access Letter to the Editor

Response to: Aspirin for patients after TIPS. An old dog with new tricks?

Leon Louis Seifert, Philipp Schindler, Dominik Bettinger, Jonel Trebicka, Moritz Wildgruber, Hauke Heinzow

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.