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Hepatology International

Issue 4/2023

Content (22 Articles)

Fatty Liver Consensus

An international multidisciplinary consensus statement on MAFLD and the risk of CVD

Xiao-Dong Zhou, Giovanni Targher, Christopher D. Byrne, Virend Somers, Seung Up Kim, C. Anwar A. Chahal, Vincent Wai-Sun Wong, Jingjing Cai, Michael D. Shapiro, Mohammed Eslam, Philippe Gabriel Steg, Ki-Chul Sung, Anoop Misra, Jian-Jun Li, Carlos Brotons, Yuli Huang, George V. Papatheodoridis, Aijun Sun, Yusuf Yilmaz, Wah Kheong Chan, Hui Huang, Nahum Méndez-Sánchez, Saleh A. Alqahtani, Helena Cortez-Pinto, Gregory Y. H. Lip, Robert J. de Knegt, Ponsiano Ocama, Manuel Romero-Gomez, Marat Fudim, Giada Sebastiani, Jang Won Son, John D. Ryan, Ignatios Ikonomidis, Sombat Treeprasertsuk, Daniele Pastori, Monica Lupsor-Platon, Herbert Tilg, Hasmik Ghazinyan, Jerome Boursier, Masahide Hamaguchi, Mindie H. Nguyen, Jian-Gao Fan, George Boon-Bee Goh, Mamun Al Mahtab, Saeed Hamid, Nilanka Perera, Jacob George, Ming-Hua Zheng

Ascites Guidelines

Asia–Pacific association for study of liver guidelines on management of ascites in liver disease

Virendra Singh, Arka De, Rohit Mehtani, Paolo Angeli, Rakhi Maiwall, Sanjaya Satapathy, Ashwini K. Singal, Anoop Saraya, B. C. Sharma, C. E. Eapen, P. N. Rao, Akash Shukla, Shalimar, Narendra S. Choudhary, Diana Alcantara-Payawal, Vinod Arora, Guru Aithal, Anand Kulkarni, Akash Roy, Ananta Shrestha, Mamun al Mahtab, Madunil A. Niriella, Tan Soek Siam, Chun-Qing Zhang, Lee Guan Huei, Ming-Lung Yu, Stuart K. Roberts, Cheng-Yuan Peng, Tao Chen, Jacob George, Vincent Wong, Yusuf Yilmaz, Sombat Treeprasertsuk, Juferdy Kurniawan, Seung Up Kim, Zobair M. Younossi, Shiv Kumar Sarin

Open Access Obesity Editorial

Obesity and non-alcoholic steatohepatitis in immunotherapy for hepatocellular carcinoma

Shuichiro Shiina, Hitoshi Maruyama, Maki Tobari, Tatsuya Yamashita

Hepatitis B Original Article

Liver-derived extracellular vesicles from patients with hepatitis B virus-related acute-on-chronic liver failure impair hepatic regeneration by inhibiting on FGFR2 signaling via miR-218-5p

Senquan Zhang, Jie Yu, Keqiang Rao, Jie Cao, Lijie Ma, Yeping Yu, Zhe Li, Zhaokai Zeng, Yongbing Qian, Mo Chen, Hualian Hang

Liver Transplantation Original Article

Messenger RNA electroporated hepatitis B virus (HBV) antigen-specific T cell receptor (TCR) redirected T cell therapy is well-tolerated in patients with recurrent HBV-related hepatocellular carcinoma post-liver transplantation: results from a phase I trial

Fan Yang, Xiaofang Zheng, Sarene Koh, Jianxi Lu, Jintao Cheng, Panlong Li, Cong Du, Yunhao Chen, Xiaoyan Chen, Li Yang, Wanxin Chen, Regina Wanju Wong, Lu‑En Wai, Tingting Wang, Qi Zhang, Wenjie Chen

Hepatitis B Original Article

Risk of dyslipidemia in chronic hepatitis B patients taking tenofovir alafenamide: a systematic review and meta-analysis

Eui Gwon Hwang, Eun-Ae Jung, Jeong-Ju Yoo, Sang Gyune Kim, Young Seok Kim

Fatty Liver Original Article

Long-term clinical outcomes of adults with metabolic dysfunction-associated fatty liver disease: a single-centre prospective cohort study with baseline liver biopsy

Wah-Loong Chan, Shi-En Chong, Felicia Chang, Lee-Lee Lai, Kee-Huat Chuah, Nik Raihan Nik Mustapha, Sanjiv Mahadeva, Wah-Kheong Chan

Fatty Liver Original Article

Polypill protects MAFLD patients from cardiovascular events and mortality: a prospective trial

Alireza Ramandi, Jacob George, Shahin Merat, Elham Jafari, Maryam Sharafkhah, Amir Reza Radmard, Alireza Nateghi Baygi, Alireza Delavari, Zahra Mohammadi, Hossein Poustchi, Reza Malekzadeh

Metastasis Original Article

Exosomal miR-200b-3p induce macrophage polarization by regulating transcriptional repressor ZEB1 in hepatocellular carcinoma

Ying Xu, Guangchao Luan, Feng Liu, Yuhua Zhang, Zhongchao Li, Ziming Liu, Tao Yang

Open Access Fatty Liver Original Article

Impact of body mass index in patients receiving atezolizumab plus bevacizumab for hepatocellular carcinoma

Mathew Vithayathil, Antonio D’Alessio, Claudia Angela Maria Fulgenzi, Naoshi Nishida, Martin Schönlein, Johann von Felden, Kornelius Schulze, Henning Wege, Anwaar Saeed, Brooke Wietharn, Hannah Hildebrand, Linda Wu, Celina Ang, Thomas U. Marron, Arndt Weinmann, Peter R. Galle, Dominik Bettinger, Bertram Bengsch, Arndt Vogel, Lorenz Balcar, Bernhard Scheiner, Pei-Chang Lee, Yi-Hsiang Huang, Suneetha Amara, Mahvish Muzaffar, Abdul Rafeh Naqash, Antonella Cammarota, Valentina Zanuso, Tiziana Pressiani, Matthias Pinter, Alessio Cortellini, Masatoshi Kudo, Lorenza Rimassa, David J. Pinato, Rohini Sharma

Open Access Hepatocellular Carcinoma Original Article

Transcatheter arterial chemoembolization plus apatinib with or without camrelizumab for unresectable hepatocellular carcinoma: a multicenter retrospective cohort study

Xuhua Duan, Hao Li, Donglin Kuang, Pengfei Chen, Kai Zhang, Yanliang Li, Xiang He, Cheng Xing, Haibo Wang, Yaoxian Liu, Limin Xie, Shixi Zhang, Qiang Zhang, Peixin Zhu, Honglin Dong, Jichen Xie, Hui Li, Yong Wang, Ming Shi, Guangbin Jiang, Yandong Xu, Shiqi Zhou, Chunyu Shang, Jianzhuang Ren, Xinwei Han

Open Access Liver Transplantation Original Article

Development of a deep pathomics score for predicting hepatocellular carcinoma recurrence after liver transplantation

Wei-Feng Qu, Meng-Xin Tian, Hong-Wei Lu, Yu-Fu Zhou, Wei-Ren Liu, Zheng Tang, Zhao Yao, Run Huang, Gui-Qi Zhu, Xi-Fei Jiang, Chen-Yang Tao, Yuan Fang, Jun Gao, Xiao-Ling Wu, Jia-Feng Chen, Qian-Fu Zhao, Rui Yang, Tian-Hao Chu, Jian Zhou, Jia Fan, Jin-Hua Yu, Ying-Hong Shi

A preoperative scoring system to predict lymph node metastasis in intrahepatic cholangiocarcinoma

Hyungjin Rhee, Hyun-Ji Lim, Kyunghwa Han, Suk-Keu Yeom, Sang Hyun Choi, Ji Hoon Park, Eun-Suk Cho, Sumi Park, Mi-Jung Lee, Gi Hong Choi, Dai Hoon Han, Seung Soo Lee, Mi-Suk Park

Open Access Hepatic Encephalopathy Original Article

Individualized portal pressure gradient threshold based on liver function categories in preventing rebleeding after TIPS

Yifu Xia, Jun Tie, Guangchuan Wang, Yuzheng Zhuge, Hao Wu, Hui Xue, Jiao Xu, Feng Zhang, Lianhui Zhao, Guangjun Huang, Mingyan Zhang, Bo Wei, Peijie Li, Wei Wu, Chao Chen, Chengwei Tang, Chunqing Zhang

Open Access Hepatic Encephalopathy Original Article

Transjugular intrahepatic collateral-systemic shunt is effective for cavernous transformation of the portal vein with variceal bleeding

Jun Tie, Xiaoyuan Gou, Chuangye He, Kai Li, Xulong Yuan, Wenyuan Jia, Jing Niu, Na Han, Jiao Xu, Ying Zhu, Wenlan Wang

Autoimmune Hepatitis Original Article

Identifying the early predictors of non-response to steroids in patients with flare of autoimmune hepatitis causing acute-on-chronic liver failure

Sanchit Sharma, Samagra Agarwal, Anoop Saraya, Ashok Kumar Choudhury, Sanjiv Saigal, A. S. Soin, Akash Shukla, Manoj K. Sahu, Laurentius A. Lesmana, Renaldi C. Lesmana, Samir N. Shah, Jinhua Hu, Soek Siam Tan, Dinesh Jothimani, Mohammed Rela, Hasmik L. Ghazinyan, D. N. Amrapurkar, C. E. Eapen, Ashish Goel, Diana Alcantra Payawal, Saeed Hamid, Amna S. Butt, Duan Zhongping, Virender Singh, Ajay Duseja, Ajit Sood, Vandana Midha, Mamun Al Mahtab, Dong Joon Kim, Qin Ning, Anand V. Kulkarni, P. N. Rao, Guan Huei Lee, Sombat Treeprasertsuk, Xin Shaojie, Md. Fazal Karim, Jose D. Sollano, Kemal Fariz Kalista, Rino Alvani Gani, V. G. Mohan Prasad, Shiv Kumar Sarin

Original Article

Downregulated VISTA enhances Th17 differentiation and aggravates inflammation in patients with acute-on-chronic liver failure

Yao Zhang, Xueyun Zhang, Jiajia Han, Yifei Guo, Feifei Yang, Fahong Li, Haoxiang Zhu, Zhongliang Shen, Yuxian Huang, Richeng Mao, Jiming Zhang

Artificial Intelligence Original Article

Artificial intelligence CT radiomics to predict early recurrence of intrahepatic cholangiocarcinoma: a multicenter study

Yangda Song, Guangyao Zhou, Yucheng Zhou, Yikai Xu, Jing Zhang, Ketao Zhang, Pengyuan He, Maowei Chen, Yanping Liu, Jiarun Sun, Chengguang Hu, Meng Li, Minjun Liao, Yongyuan Zhang, Weijia Liao, Yuanping Zhou

Open Access Original Article

Contribution of alcohol use to the global burden of cirrhosis and liver cancer from 1990 to 2019 and projections to 2044

Yang Liu, Zhouyi Sun, Qianwen Wang, Kangze Wu, Zhe Tang, Bo Zhang

Open Access Ascites Original Article

Bacterial translocation occurs early in cirrhosis and triggers a selective inflammatory response

Benedikt Simbrunner, Esther Caparrós, Teresa Neuwirth, Philipp Schwabl, Philipp Königshofer, David Bauer, Rodrig Marculescu, Michael Trauner, Bernhard Scheiner, Georg Stary, Mattias Mandorfer, Thomas Reiberger, Rubén Francés

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.