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Digestive Diseases and Sciences

Issue 4/2023

Content (65 Articles)

Endoscopy Image of the Month

Speckled Pigment of Upper GI Tract Mucosa on Endoscopy: A Case of Pseudomelanosis of the Stomach and Proximal Small Bowel

Kian Abdul-Baki, Obada Hisham Saeed Tayyem, Paul Young, Suimin Qiu, Jose Aguirre

Venous Thrombosis Image of the Month

Ischemic Jejunal Stricture Secondary to Polycythemia Vera

Ashley McFarquhar, Firas Bahdi, Ya Xu, Lee B. Lu

Irritable Bowel Syndrome Invited Commentary

Non-celiac Gluten Intolerance: A Call to Clarify

Jacqueline Jossen, Benjamin Lebwohl

Fellows and Young GIs Section

Transplant Hepatology Fellowship Websites: The Good, the Bad, and the Unhelpful

Faraz I. Jafri, Alexis de Montfort Shepherd, Pralahad Raman, Thomas C. Varkey, Charles Hyman, Deepak Agrawal

Relationship Between Esophageal Disease and Pulmonary Fibrosis

Joyce C. Zhou, Sravanya Gavini, Walter W. Chan, Wai-Kit Lo

Tuberculosis DDS–SIRC COOPERATIVE CONFERENCES

Une Liaison Dangereuse: Spontaneous Pyeloduodenal Fistula

Patrizia Alba Gentile, Loredana Gualtieri, Silvia Izzo, Klaudia Luka, Augusto Lauro, Bruno Salvati

Basic Surgery DDS-SIRC Author Profile

Author Spotlight: Patrizia Alba Gentile

Patrizia Alba Gentile

Infliximab Multicenter Seminars: IBD (MUSE: IBD)

On a Knife’s Edge: Management of Vulvar Cutaneous Crohn’s Disease

Nicole S. Evans, Fernando S. Velayos

Laryngoscopy Original Article

Best Practices in Treatment of Laryngopharyngeal Reflux Disease: A Multidisciplinary Modified Delphi Study

Afrin N. Kamal, Shumon I. Dhar, Jonathan M. Bock, John O. Clarke, Jerome R. Lechien, Jacqueline Allen, Peter C. Belafsky, Joel H. Blumin, Walter W. Chan, Ronnie Fass, P. Marco Fisichella, Michael Marohn, Ashli K. O’Rourke, Gregory Postma, Edoardo V. Savarino, Michael F. Vaezi, Thomas L. Carroll, Lee M. Akst

Cholangiocarcinoma Original Article

Clinical Outcomes of Inside Stents and Conventional Plastic Stents as Bridge-to-Surgery Options for Malignant Hilar Biliary Obstruction

Hirotoshi Ishiwatari, Takanori Kawabata, Hiroki Kawashima, Yousuke Nakai, Shin Miura, Hironari Kato, Hideyuki Shiomi, Nao Fujimori, Takeshi Ogura, Osamu Inatomi, Kensuke Kubota, Toshio Fujisawa, Mamoru Takenaka, Hiroshi Mori, Kensaku Noguchi, Yuki Fujii, Teiichi Sugiura, Noboru Ideno, Tomoki Nakafusa, Atsushi Masamune, Hiroyuki Isayama, Naoki Sasahira

Endoscopy Original Article

A National Survey of the Infrastructure and Scope of Practice for Gastroenterology Hospitalists

David W. Wan, Melissa Latorre, Edward Sun, Michelle L. Hughes, Adam Buckholz, Darrick K. Li

Ulcerative Colitis Original Article

Impact of Disease Activity and Inflammatory Bowel Disease Subtype on Quality of Life in Preconception and Pregnant Patients

Grace Wang, Parul Tandon, Nicole Rodriguez, Lindsy Ambrosio, Reed T. Sutton, Levinus A. Dieleman, Karen I. Kroeker, Vivian Huang

Endoscopy Original Article

Endoscopic Ultrasound-Directed Transgastric ERCP (EDGE) Utilization of Trends Among Interventional Endoscopists

Sardar M. Shah-Khan, Eric Zhao, Amy Tyberg, Sardar Sarkar, Haroon M. Shahid, Rodrigo Duarte-Chavez, Monica Gaidhane, Michel Kahaleh

Esophageal Cancer Original Article

Impact of Medicaid Expansion on Incidence and Mortality from Gastric and Esophageal Cancer

Elaheh Niroomand, Smriti Rajita Kumar, David Goldberg, Shria Kumar

Original Article

Gastroesophageal Balloon Tamponade Simulation Training with 3D Printed Model Improves Knowledge, Skill, and Confidence

Christopher Mowry, Ruhail Kohli, Courtney Bhat, Aimee Truesdale, Paul Menard-Katcher, Andrew Scallon, Michael Kriss

Original Article

Existing Bowel Preparation Quality Scales Are Reliable in the Setting of Centralized Endoscopy Reading

Jurij Hanzel, Michael Sey, Christopher Ma, Guangyong Zou, James E. East, Corey A. Siegel, Mahmoud Mosli, Walter Reinisch, John W. D. McDonald, Mark S. Silverberg, Tanja Van Viegen, Lisa M. Shackelton, Lucy B. Clayton, Robert Enns, Ian Epstein, Robert J. Hilsden, Lawrence Hookey, Dana C. Moffatt, Richard Ng Kwet Shing, Jennifer J. Telford, Daniel von Renteln, Brian G. Feagan, Alan Barkun, Vipul Jairath

Open Access COVID-19 Original Article

COVID-19 Pandemic Had Minimal Impact on Colonoscopy Completion After Colorectal Cancer Red Flag Sign or Symptoms in US Veterans

Joshua Demb, Lin Liu, Ranier Bustamante, Jason A. Dominitz, Ashley Earles, Shailja C. Shah, Andrew J. Gawron, Maria Elena Martinez, Samir Gupta

Open Access Crohn's Disease Original Article

Crohn’s Disease Among the Poorest Billion: Burden of Crohn’s Disease in Low- and Lower-Middle-Income Countries

Ruma Rajbhandari, Samantha Blakemore, Neil Gupta, Sara Mannan, Klejda Nikolli, Alison Yih, Laura Drown, Gene Bukhman

Original Article

Hydrogen Availability Is Dependent on the Actions of Both Hydrogen-Producing and Hydrogen-Consuming Microbes

Aleksandr Birg, Nathaniel Ritz, Larry L. Barton, Henry C. Lin

Open Access Motility Disorder Original Article

“M1/M2” Muscularis Macrophages Are Associated with Reduction of Interstitial Cells of Cajal and Glial Cells in Achalasia

Haisheng Qian, Yanjuan Wang, Xiaosu Chen, Lin Lin, Weifeng Zhang, Yun Wang, Nana Tang, Xinmin Si, Chunhua Jiao, Guoxin Zhang, Bixing Ye

Depression Exacerbates Dextran Sulfate Sodium-Induced Colitis via IRF5-Mediated Macrophage Polarization

Chang Liang, Yu Tang, Xin Gao, Na Lei, Ying Luo, Pingrun Chen, Shihao Duan, Yubin Cao, Yi Yang, Yan Zhang

Portal Vein Thrombosis Original Article

Liver Cirrhosis Patients Homozygous for MTHFR C677T Develop Portal Vein Thrombosis 8 Years Earlier Than Wild Type

Paul R. J. Ames, Giovanna D’Andrea, Alessia Arcaro, Vincenzo Marottoli, Luigi Iannaccone, Maurizio Maraglione, Fabrizio Gentile

Pancreatic Cancer Original Article

NEDD8-Activating Enzyme Inhibitor MLN4924 Inhibits Both the Tumor Stroma and Angiogenesis in Pancreatic Cancer via Gli1 and REDD1

Weilin Mao, Lei Zhang, Yefei Rong, Tiantao Kuang, Dansong Wang, Xuefeng Xu, Wenhui Lou, Jianang Li

Self-Reported Gluten Intolerance Is Prevalent, but Not All Gluten-Containing Foods Are Equal

Claire L. Jansson-Knodell, Mattie White, Carolyn Lockett, Huiping Xu, Alberto Rubio-Tapia, Andrea Shin

Celiac Disease Original Article

Bi-directional Relationship Between Celiac Disease and Liver Chemistries: A Systematic Review and Meta-Analysis

Manik Aggarwal, Rajat Garg, Prabhat Kumar, Christina C. Lindenmeyer, Jamile Wakim-Fleming, Claire Jansson-Knodell, Alberto Rubio-Tapia

Esophageal Varices Original Article

Band Ligation Can Be Used to Treat Barrett’s Esophagus and Concurrent Esophageal Varices: A Case Series

Colin Hartgerink, Faisal M. Nimri, Tobias Zuchelli, Syed-Mohammed Jafri, Cyrus Piraka

Esophagitis Original Article

Mid-Term and Long-Term Outcomes of Peroral Endoscopic Myotomy for the Treatment of Achalasia: A Systematic Review and Meta-Analysis

Han Zhang, Xinyi Zeng, Shu Huang, Lei Shi, Huifang Xia, Jiao Jiang, Wensen Ren, Yan Peng, Muhan Lü, Xiaowei Tang

Alopecia Original Article

Hair Loss in Patients with Gastroparesis: A Sign of Nutritional Deficiency in Gastroparesis?

Paul J. Silver, Michael J. Coles, Candrice R. Heath, Henry P. Parkman

Age- and Gender-Based Differences in Anorectal Function, Gastrointestinal Symptoms, and Constipation-Specific Quality of Life in Patients with Chronic Constipation

Borko Nojkov, Jason R. Baker, William D. Chey, Richard Saad, Lydia Watts, Moira Armstrong, Kristen Collins, Gabrielle Ezell, Cari Phillips, Stacy Menees

Original Article

Cap-Assisted Endoscopic Esophageal Foreign Body Removal Is Safe and Efficacious Compared to Conventional Methods

Zohaib Ahmed, Syeda Faiza Arif, Stephanie Lin Ong, Joyce Badal, Wade Lee-Smith, Anas Renno, Yaseen Alastal, Ali Nawras, Muhammad Aziz

Open Access Endoscopy Original Article

Safety and Efficacy of Sedation During Emergency Endoscopy for Upper Gastrointestinal Bleeding: A Propensity Score Matching Analysis

Daisuke Yamaguchi, Goshi Nagatsuma, Yasuhisa Sakata, Yumi Mizuta, Tadahiro Nomura, Azuki Jinnouchi, Kasumi Gondo, Ryosuke Asahi, Satoshi Ishida, Shunichiro Kimura, Shun Fujimoto, Akane Shimakura, Amane Jubashi, Yuki Takeuchi, Kei Ikeda, Yuichiro Tanaka, Wataru Yoshioka, Naoyuki Hino, Tomohito Morisaki, Keisuke Ario, Seiji Tsunada, Motohiro Esaki

Endoscopy Original Article

Erythromycin Improves the Quality of Esophagogastroduodenoscopy in Upper Gastrointestinal Bleeding: A Network Meta-Analysis

Muhammad Aziz, Hossein Haghbin, Manesh Kumar Gangwani, Simcha Weissman, Arti R. Patel, Manraj K. Randhawa, Luke B. Samikanu, Zakaria Abdullah Alyousif, Wade Lee-Smith, Faisal Kamal, Ali Nawras, Colin W. Howden

Open Access Other Abdominal Surgery Original Article

Motorized Spiral Enteroscopy Is Effective in Patients with Prior Abdominal Surgery

Antonio Giordano, Gherzon Casanova, Miriam Escapa, Gloria Fernández-Esparrach, Àngels Ginès, Oriol Sendino, Isis K. Araujo, Andrés Cárdenas, Henry Córdova, Julia Martínez-Ocon, Graciela Martínez-Palli, Francesc Balaguer, Josep Llach, Elena Ricart, Begoña González-Suárez

Ulcerative Colitis Original Article

Endo-histologic Normalization Is Achievable with Tofacitinib and Is Associated with Improved Clinical Outcomes

Nathaniel A. Cohen, Joshua M. Steinberg, Alexa Silfen, Cindy Traboulsi, Tina G. Rodriguez, Jorie M. Singer, Shivani Patel, Russell D. Cohen, Sushila R. Dalal, Atsushi Sakuraba, Joel Pekow, Dejan Micic, David T. Rubin

Colonoscopy Original Article

Fecal Microbiome Associated with Both Colon Adenomas and Lifetime Colorectal Cancer Risk

Sarah Alharfi, Nancy Furey, Hilmi Al-Shakhshir, Mahmoud Ghannoum, Gregory S. Cooper

Chronic Pancreatitis Original Article

Efficacy and Predictors of Pain Response to Combined Antioxidants in Children with Chronic Pancreatitis

Amrit Gopan, Anshu Srivastava, Amrita Mathias, Surender Kumar Yachha, Sunil Kumar Jain, Prabhakar Mishra, Moinak Sen Sarma, Ujjal Poddar

Pancreatic Cyst Original Article

Stratification Based on Risk Factors at Diagnosis Could Predict Progression in Patients with Pancreatic Cysts

Ryo Sugio, Tsutomu Nishida, Kengo Matsumoto, Kosuke Kawamura, Miyoung Park, Tomoya Hamabe, Kana Hosokawa, Shinji Kuriki, Li-sa Chang, Yoshifumi Fujii, Naoto Osugi, Aya Sugimoto, Kaori Mukai, Dai Nakamatsu, Shiro Hayashi, Masashi Yamamoto, Sachiko Nakajima, Koji Fukui, Masami Inada

Pancreatic Surgery Original Article

Pre-existing, Concurrent/Early-Onset, and Late-Onset Diabetes in Chronic Pancreatitis: Do Outcomes Differ?

Shaharyar A. Zuberi, Ishani Shah, Rachel L. Bocchino, Awais Ahmed, Steven D. Freedman, Darshan J. Kothari, Sunil G. Sheth

Pancreatic Cancer Original Article

The Frequency of Germline BRCA and Non-BRCA HR-Gene-Variants in a Cohort of Pancreatic Cancer Patients

M. Baz, V. Gondran-Teiller, B. Bressac, O. Cabaret, A. Fievet, M. Dimaria, V. Goldbarg, C. Colas, M. N. Bonnet-Dupeyron, J. Tinat, M. Lebrun, V. Mari, J. M. Limacher, C. Corsini, E. Ginglinger, J. C. Saurin, A. Brahimi, C. Rouzier, S. Giraud, H. Schuster, A. Hollebecque, V. Boige, E. Cauchin, D. Malka, O. Caron, E. Rouleau

Cholecystitis Original Article

Long-Term Impact of Endoscopic Gallbladder Stenting for Calculous Cholecystitis in Poor Surgical Candidates: A Multi-center Comparative Study

Tadahisa Inoue, Yuta Suzuki, Michihiro Yoshida, Itaru Naitoh, Fumihiro Okumura, Rena Kitano, Kenichi Haneda, Kazuki Hayashi, Masashi Yoneda

Endoscopy Original Article

Clinical Outcomes of Patients with Benign Peptic Ulcer Bleeding After an Emergency Endoscopy Based on Patient Location

Boram Cha, Jin Hee Noh, Ji Yong Ahn, Jun Su Lee, Ga Hee Kim, Hee Kyong Na, Kee Wook Jung, Jeong Hoon Lee, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung

Ultrasound Original Article

Endoscopic Ultrasound-Guided Antegrade Stent Placement in Patients with Failed ERCP as a Modality of Preoperative and Palliative Biliary Drainage

Sridhar Sundaram, Kiran Mane, Prachi Patil, Raosaheb Rathod, Aadish Kumar Jain, Unique Tyagi, Shaesta Mehta

Hepatitis B Original Article

Concomitant Diseases and Co-contribution on Progression of Liver Stiffness in Patients with Hepatitis B Virus Infection

Chang-Hai Liu, Wei Jiang, Dong-Bo Wu, Qing-Min Zeng, You-Juan Wang, Hong Tang

Sarcopenia Original Article

Sarcopenia Defined by Psoas Muscle Thickness Predicts Mortality After Transjugular Intrahepatic Portosystemic Shunt

Tongqiang Li, Jiacheng Liu, Jianbo Zhao, Yaowei Bai, Songjiang Huang, Chongtu Yang, Yingliang Wang, Chen Zhou, Chaoyang Wang, Shuguang Ju, Yang Chen, Wei Yao, Bin Xiong

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.