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BMC Immunology

Issue 1/2019

Content (49 Articles)

Open Access Kaposi's Sarcoma-Associated Herpesvirus Research article

Mannose-binding lectin concentrations in people living with HIV/AIDS infected by HHV-8

Viviane Martha Santos de Morais, Juliana Prado Gonçales, Georgea Gertrudes de Oliveira Mendes Cahú, Tania Regina Tozetto-Mendoza, Maria Rosângela Cunha Duarte Coêlho

Open Access Human Immunodeficiency Virus Research article

Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection

Raghubendra Singh Dagur, Amanda Branch-Woods, Saumi Mathews, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Yan Cheng, Shana M. Miles, Samuel J. Pirruccello, Channabasavaiah B. Gurumurthy, Santhi Gorantla, Larisa Y. Poluektova

Open Access Bronchial Asthma Research article

Treatment of established TH2 cells with 4μ8c, an inhibitor of IRE1α, blocks IL-5 but not IL-4 secretion

Cody Poe, Cheyanne Youngblood, Karissa Hodge, Kyeorda Kemp

Open Access Thymoma Research article

Correlate tumor mutation burden with immune signatures in human cancers

Xiaosheng Wang, Mengyuan Li

Open Access Research article

Phenotypic and functional stability of leukocytes from human peripheral blood samples: considerations for the design of immunological studies

Adriana Navas, Lina Giraldo-Parra, Miguel Darío Prieto, Juliana Cabrera, María Adelaida Gómez

Open Access Research article

Monoclonal antibody against EV71 3Dpol inhibits the polymerase activity of RdRp and virus replication

Yaoming Li, Jie Yu, Xiuwen Qi, Huimin Yan

Open Access Research article

CEACAM1 regulates the IL-6 mediated fever response to LPS through the RP105 receptor in murine monocytes

Zhifang Zhang, Deirdre La Placa, Tung Nguyen, Maciej Kujawski, Keith Le, Lin Li, John E. Shively

Open Access Research article

Expression of ligands for activating natural killer cell receptors on cell lines commonly used to assess natural killer cell function

Alexandra Tremblay-McLean, Sita Coenraads, Zahra Kiani, Franck P. Dupuy, Nicole F. Bernard

Open Access Alzheimer's Disease Research article

Active immunization with norovirus P particle-based amyloid-β chimeric protein vaccine induces high titers of anti-Aβ antibodies in mice

Ping Yang, Yongqing Guo, Yao Sun, Bin Yu, Haihong Zhang, Jiaxin Wu, Xianghui Yu, Hui Wu, Wei Kong

Open Access Miscarriage Research article

Patients with idiopathic recurrent miscarriage have abnormally high TGFß+ blood NK, NKT and T cells in the presence of abnormally low TGFß plasma levels

Li Zhu, Mostafa Aly, Ruben Jeremias Kuon, Bettina Toth, Haihao Wang, Hristos Karakizlis, Rolf Weimer, Christian Morath, Eman Ibrahim, Naruemol Ekpoom, Gerhard Opelz, Volker Daniel

Open Access Research article

A novel approach reveals that HLA class 1 single antigen bead-signatures provide a means of high-accuracy pre-transplant risk assessment of acute cellular rejection in renal transplantation

Nicole Wittenbrink, Sabrina Herrmann, Arturo Blazquez-Navarro, Chris Bauer, Eric Lindberg, Kerstin Wolk, Robert Sabat, Petra Reinke, Birgit Sawitzki, Oliver Thomusch, Christian Hugo, Nina Babel, Harald Seitz, Michal Or-Guil

Open Access Plasmodium Falciparum Research article

Immunoglobulin G responses against falciparum malaria specific antigens are higher in children with homozygous sickle cell trait than those with normal hemoglobin

George Msema Bwire, Mtebe Majigo, Robert Makalla, Lillian Nkinda, Akili Mawazo, Mucho Mizinduko, Julie Makani

Open Access Research article

Tristetraprolin specifically regulates the expression and alternative splicing of immune response genes in HeLa cells

Yafang Tu, Xiongfei Wu, Fengyun Yu, Jianzhong Dang, Juan Wang, Yaxun Wei, Zhitao Cai, Zhipeng Zhou, Wenliang Liao, Lian Li, Yi Zhang

Open Access Pneumonia Research article

Clinical and laboratory associations of mannose-binding lectin in 219 adults with IgG subclass deficiency

James C. Barton, Jackson C. Barton, Luigi F. Bertoli

Open Access Kawasaki Disease Research article

Distinct variations of antibody secreting cells and memory B cells during the course of Kawasaki disease

Meng Xu, Yanfang Jiang, Jinghua Wang, Jinxiang Liu, Congcong Liu, Deying Liu, Sirui Yang

Open Access Eosinophilia Research article

Similar immune mechanisms control experimental airway eosinophilia elicited by different allergens and treatment protocols

Evelyn J. Hyde, Kirsty A. Wakelin, Naomi J. Daniels, Sayani Ghosh, Franca Ronchese

Open Access Research article

Longitudinal immunosequencing in healthy people reveals persistent T cell receptors rich in highly public receptors

Nathaniel D. Chu, Haixin Sarah Bi, Ryan O. Emerson, Anna M. Sherwood, Michael E. Birnbaum, Harlan S. Robins, Eric J. Alm

Open Access Obesity Research article

Association of proinflammatory genes expression with serum interleukin 1β and free fatty acids in metabolically healthy and unhealthy abdominally obese individuals: a case-control study

Parichehr Amiri, Behzad Baradaran, Maryam Saghafi-Asl, Mahsa Naghizadeh, Dariush Shanehbandi, Nahid Karamzad, Sepideh Zununi Vahed

Open Access Multiple Sclerosis Research article

Changes of B cell subsets in central pathological process of autoimmune encephalomyelitis in mice

Yingqiong Xiong, Shaomin Cheng, Xiaomu Wu, Yue Ren, Xufang Xie

Open Access Plasmodium Falciparum Research article

Identification of adjuvants for clinical trials performed with Plasmodium falciparum AMA1 in rabbits

Sumera Younis, Bart W. Faber, Clemens H.M. Kocken, Edmond J. Remarque

Open Access Research article

Increased circulating Tfh to Tfr ratio in chronic renal allograft dysfunction: a pilot study

Lin Yan, Yamei Li, Yi Li, Xiaojuan Wu, Xianding Wang, Lanlan Wang, Yunying Shi, Jiangtao Tang

Open Access Hepatitis B Research article

CD4+ T cell exhaustion revealed by high PD-1 and LAG-3 expression and the loss of helper T cell function in chronic hepatitis B

Yuejiao Dong, Xuefen Li, Lu Zhang, Qiaoyun Zhu, Chunlei Chen, Jiaqi Bao, Yu Chen

Open Access Systemic Lupus Erythematosus Research article

Comprehensive analyses of long non-coding RNA expression profiles by RNA sequencing and exploration of their potency as biomarkers in psoriatic arthritis patients

Tao Yue, Mei Ji, Huanru Qu, Mengru Guo, Fengmin Bai, Zhanming Zhang, Weifeng Wang, Xuming Gong, Zhenghua Zhang

Open Access Primary Immunodeficiency Research article

Pneumococcal vaccination responses in adults with subnormal IgG subclass concentrations

Antony R. Parker, Markus Skold, Stephen Harding, J. Clayborn Barton, Luigi F. Bertoli, James C. Barton

Open Access Multiple Sclerosis Research article

Genetic polymorphisms and epigenetic regulation of survivin encoding gene, BIRC5, in multiple sclerosis patients

Dariush Rahban, Forogh Mohammadi, Mehdi Alidadi, Taha Ghantabpour, Pedram Abbasi Ghasem Kheyli, Majid Ahmadi

Open Access Human Immunodeficiency Virus Research article

The predictive role of CD4+ cell count and CD4/CD8 ratio in immune reconstitution outcome among HIV/AIDS patients receiving antiretroviral therapy: an eight-year observation in China

Chong-Xi Li, Yu-Ye Li, Li-Ping He, Jing Kou, Jin-Song Bai, Jun Liu, Bo Tian, Li-Juan Cao, Kun-Hua Wang, Yi-Qun Kuang

Open Access Systemic Lupus Erythematosus Research article

Low dose of IL-2 combined with rapamycin restores and maintains the long-term balance of Th17/Treg cells in refractory SLE patients

Chunmiao Zhao, Yanfang Chu, Zhaoyun Liang, Bingying Zhang, Xuxia Wang, Xiaona Jing, Meihua Hao, Yiqi Wang, Jia An, Xingzhe Zhang, Liguang Sun, Junwei Chen

Open Access Cytokines Research article

Biological variation of immunological blood biomarkers in healthy individuals and quality goals for biomarker tests

Najib Aziz, Roger Detels, Joshua J. Quint, David Gjertson, Timothy Ryner, Anthony W. Butch

Open Access Methodology article

Simple propagation method for resident macrophages by co-culture and subculture, and their isolation from various organs

Kazushige Ogawa, Mayu Tsurutani, Aya Hashimoto, Miharu Soeda

Open Access Tuberculosis Research article

Enhanced IFN-γ, but not IL-2, response to Mycobacterium tuberculosis antigens in HIV/latent TB co-infected patients on long-term HAART

Girmay Desalegn, Aster Tsegaye, Dawit Gebreegziabiher, Abraham Aseffa, Rawleigh Howe

Open Access Tuberculosis Research article

IgA and IgG antibody detection of mycobacterial antigens in pleural fluid and serum from pleural tuberculous patients

Renan Jeremias da Silva, Raquel da Silva Corrêa, Isabela Gama Sardella, Ana Carla de Paulo Mulinari, Thiago Thomaz Mafort, Ana Paula Santos, Rogério Rufino, Luciana Silva Rodrigues, Maria Helena Féres Saad

Open Access Human Immunodeficiency Virus Research article

Foxp3+Helios+ regulatory T cells are associated with monocyte subsets and their PD-1 expression during acute HIV-1 infection

Lifeng Liu, Qiuyue Zhang, Peng Chen, Na Guo, Aixin Song, Xiaojie Huang, Wei Xia, Li Li, Christiane Moog, Hao Wu, Bin Su, Tong Zhang

Open Access Stem Cell Transplantation Research article

Low pre-transplant levels of mannose-binding lectin are associated with viral infections and mortality after haematopoietic allogeneic stem cell transplantation

M. Puente, C. Fariñas-Alvarez, A. Moreto, P. Sánchez-Velasco, J. G. Ocejo-Vinyals, M. C. Fariñas

Open Access Infliximab Research article

Subsets of mononuclear phagocytes are enriched in the inflamed colons of patients with IBD

Hong Liu, Suryasarathi Dasgupta, Yu Fu, Brandi Bailey, Christian Roy, Eric Lightcap, Benjamin Faustin

Open Access NSCLC Research article

Immunogenicity of Del19 EGFR mutations in Chinese patients affected by lung adenocarcinoma

Deng Pan, Dapeng Zhou, Weijing Cai, Weibo Wu, Wen Ling Tan, Caicun Zhou, Yanyan Lou

Open Access Arthritis Research article

Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-μTP-L309C, a recombinant IgG1 Fc hexamer

Bonnie J. B. Lewis, Jade Ville, Megan Blacquiere, Selena Cen, Rolf Spirig, Adrian W. Zuercher, Fabian Käsermann, Donald R. Branch

Open Access Tuberculosis Research article

The effect of tuberculosis on immune reconstitution among HIV patients on highly active antiretroviral therapy in Adigrat general hospital, eastern Tigrai, Ethiopia; 2019: a retrospective follow up study

Hadush Negash, Haftom Legese, Mebrahtu Tefera, Fitsum Mardu, Kebede Tesfay, Senait Gebresilasie, Berhane Fseha, Tsega Kahsay, Aderajew Gebrewahd, Brhane Berhe

Open Access Aplastic Anemia Research article

NK cell predicts the severity of acute graft-versus-host disease in patients after allogeneic stem cell transplantation using antithymocyte globulin (ATG) in pretreatment scheme

Ping Zhang, Shujun Yang, Yujing Zou, Xiao Yan, Hao Wu, Miao Zhou, Yong Cheng Sun, Yi Zhang, Huiling Zhu, Kaihong Xu, Yi Wang, Li Xia Sheng, Qitian Mu, Liguang Sun, Guifang Ouyang

Open Access Arterial Occlusive Disease Research article

ILC2 transfers to apolipoprotein E deficient mice reduce the lipid content of atherosclerotic lesions

Polyxeni T. Mantani, Pontus Dunér, Irena Ljungcrantz, Jan Nilsson, Harry Björkbacka, Gunilla Nordin Fredrikson

Open Access Research article

Amentoflavone ameliorates cold stress-induced inflammation in lung by suppression of C3/BCR/NF-κB pathways

Jiayi Cai, Chunyang Zhao, Yajie Du, Yuan Huang, Qingchun Zhao

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.