Glioblastoma remains resistant to most conventional treatments. Emerging therapies aim to overcome the challenges posed by the blood–brain barrier and tumor microenvironment.
Poor dental health can lead to life-threatening CNS infections, even in a healthy individual. This is the first case of ventriculitis caused by an oral pathogen.
Recent clinical trials in glioblastoma have investigated a wide variety of therapeutic options, such as targeted agents, immunotherapies, and vaccine-based therapies. Find out more in this review.
Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
Poor dental health can lead to life-threatening CNS infections, even in a healthy individual. This is the first case of ventriculitis caused by an oral pathogen.
How should you react to an acute MI immediately after a craniotomy for tumor resection? Management of such patients requires carefully balancing the competing risks of myocardial ischemia and postoperative bleeding.
Pediatric optic pathway/hypothalamic gliomas (OPHG) pose challenges in treatment due to their location and proximity to vital structures. Surgical resection plays a key role in the management of OPHG especially when the tumor exhibits mass effect …
Immunotherapy for glioblastoma (GBM) remains an intensive area of investigation. Given the seismic impact of cancer immunotherapy across a range of malignancies, there is optimism that harnessing the power of immunity will influence GBM as well.
Central nervous system (CNS) tumors are the most frequent solid tumors in children, making CNS tumors the leading cause of cancer-related death in children. Beyond CNS tumors, pediatric-type low-grade gliomas (pLGG) are the most frequent childhood …
External hydrocephalus is an infant condition that has been defined with many synonyms (external hydrocephalus [ 1 – 5 ], benign external hydrocephalus [ 6 , 7 ], benign pericerebral collection, pericerebral hygromas [ 8 ], benign enlargement of …
Neuroimaging plays an increasingly critical role in clinical practice. PET Pearls is an interactive activity designed to improve your confidence and accuracy when interpreting imaging for early signs of cognitive impairment.
STEM-PD, the first in-human safety trial of stem cell therapy for Parkinson’s disease, began this year and marks a huge step forward for this type of treatment.
We talk to Prof. Malin Parmar about why stem cell therapy is such a good option for patients with Parkinson’s disease and get an update on the current status of the trial.
Intracranial meningiomas often recur even after gross total resection with and without adjuvant radiation treatment, with a rate ranging from 10 to 32% at 10 years [ 1 , 2 ]. The main risk factors include the WHO grade [ 3 – 5 ], the proliferation …
Medulloblastoma (MB) is the most common brain malignancy in pediatric patients, which accounts for 20–25% of pediatric central nervous system neoplasms [ 1 , 2 ]. Despite the increase in survival rates in recent years, prognosis of MB patients …
Endoscopic third ventriculostomy (ETV) is a well-established surgical technique for treating hydrocephalus. Many providers have transitioned to utilizing the specialized Neuroballoon for the stoma dilation in ETV; however, these devices are …
Glioblastoma (GBM) is the most aggressive glioma recurring on a regular basis despite extensive tumor treatment and usually resulting into a limited overall survival (OS) [ 1 ]. Although GBM is a clearly defined entity on a histological and …
Glioblastoma remains resistant to most conventional treatments. Emerging therapies aim to overcome the challenges posed by the blood–brain barrier and tumor microenvironment.
Poor dental health can lead to life-threatening CNS infections, even in a healthy individual. This is the first case of ventriculitis caused by an oral pathogen.
