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Traumatic Brain Injuries 

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  1. Open Access 01-12-2024 | Central Nervous System Trauma | OriginalPaper

    Efficacy of a virtual reality-based cognitive interactive training program for children with traumatic brain injuries: study protocol for a parallel-group randomized controlled trial

    Note: the numbers in curly brackets in this protocol refer to the SPIRIT checklist item numbers. The order of the items has been modified to group similar items (see …

  2. 16-02-2023 | Central Nervous System Trauma | OriginalPaper

    Utility of intracranial pressure monitoring in patients with traumatic brain injuries: a propensity score matching analysis of TQIP data

    The primary insult in traumatic brain injury (TBI) is often irreversible. Therefore, TBI management is targeted towards the prevention and mitigation of secondary insult due to intracranial hypertension which is associated with an increased …

  3. 20-09-2023 | Central Nervous System Trauma | OriginalPaper

    A multicenter observational study on outcomes of moderate and severe pediatric traumatic brain injuries—time to reappraise thresholds for treatment

    Traumatic brain injury (TBI) is a leading cause of death and disability in children. In the USA, more than 640,000 children are admitted to the emergency room each year with TBI [ 28 ]. Outcomes vary depending on the severity of TBI. Those with …

  4. Open Access 01-12-2022 | Central Nervous System Trauma | OriginalPaper

    A predictive model for postoperative progressive haemorrhagic injury in traumatic brain injuries

    Nearly 50 million people worldwide suffer from traumatic brain injury (TBI) each year [ 1 ]. According to a study by the Global Burden of Disease, the prevalence of TBI increased by 8.4% between 1990 and 2016 [ 2 ].C,oagulopathy is a common …

  5. 01-04-2023 | Central Nervous System Trauma | OriginalPaper

    Acute Treatment with the M-Channel (Kv7, KCNQ) Opener Retigabine Reduces the Long-Term Effects of Repetitive Blast Traumatic Brain Injuries

    We investigated whether pharmacological increase of “M-type” (KCNQ, Kv7) K + channel currents by the M-channel opener, retigabine (RTG), acutely after repetitive traumatic brain injuries (rTBIs), prevents or reduces their long-term detrimental …

  6. 16-09-2023 | Central Nervous System Trauma | Online First

    Intimate Partner Violence Reporting and Assessment of Traumatic Brain Injuries and Strangulation by a New Zealand Hospital Health Service

    Intimate Partner Violence (IPV), also called spousal abuse, is any physical or sexual violence, psychological/emotional abuse, or threat of physical or sexual violence that occurs between people in an intimate relationship of any sex (Baxter & …

  7. 24-05-2022 | Central Nervous System Trauma | ReviewPaper

    Traumatic brain injuries and maxillofacial fractures: a systematic review and meta-analysis

    Traumatic brain injuries (TBIs) associated with maxillofacial fractures (MFFs) are a public health concern worldwide, especially among adult-aged males. There is an urgent need for early detection of associated TBIs in patients with MFFs during …

  8. Open Access 01-12-2023 | Central Nervous System Trauma | OriginalPaper

    Prediction performance of the machine learning model in predicting mortality risk in patients with traumatic brain injuries: a systematic review and meta-analysis

    Traumatic brain injury (TBI) is a major global health problem, with 950,000 TBI cases per year [ 1 ], which is mainly triggered by falls and road injuries. With an increasing population density, the aging of the population, and the use of motor …

  9. Open Access 01-12-2023 | Headache | OriginalPaper

    Repeat mild traumatic brain injuries (RmTBI) modify nociception and disrupt orexinergic connectivity within the descending pain pathway

    Repeat mild traumatic brain injuries (RmTBI) result in substantial burden to the public health system given their association with chronic post-injury pathologies, such as chronic pain and post-traumatic headache. Although this may relate to …

  10. Open Access 03-12-2021 | Central Nervous System Trauma | OriginalPaper

    Comparison of the predictive value of two international guidelines for safe discharge of patients with mild traumatic brain injuries and associated intracranial pathology

    Traumatic brain injuries are common in all parts of the world [ 1 ]. Incidences in Europe vary between 47.3 and 849 per 100,000 of the population, according to a systematic review by Brazinova et al. [ 2 ]. These rates are similar and relatively …

  11. Open Access 01-12-2023 | Central Nervous System Trauma | OriginalPaper

    War-related traumatic brain injuries during the Syrian armed conflict in Damascus 2014–2017: a cohort study and a literature review

    The decade-long Syrian armed conflict (SAC) has become the most devastating humanitarian crisis of our time, affecting the lives of millions, and keeping Syria the most dangerous country worldwide for five years [ 1 , 2 ]. Various lethal weapons …

  12. 01-06-2021 | Central Nervous System Trauma | OriginalPaper

    The influence of the COVID-19 pandemic on traumatic brain injuries in Tyrol: experiences from a state under lockdown

    Traumatic brain injury (TBI) remains the largest contributor to trauma-related mortality worldwide with considerable economic and social impact, particularly, for affected individuals, their families and socioeconomic systems [ 1 ]. Despite …

  13. 01-12-2020 | Central Nervous System Trauma | Original Research

    Methylphenidate improves executive functions in patients with traumatic brain injuries: a feasibility trial via the idiographic approach

    At least 1 million people from all across the world sustain traumatic brain injury (TBI) each year [ 1 ]. Accompanying this statistic is an increasing recognition that TBI is a leading cause of death and disability [ 2 – 4 ] as well. Importantly …

  14. 27-05-2022 | Central Nervous System Trauma | OriginalPaper

    Impact of Factor Xa Inhibitor Reversal with Prothrombin Complex Concentrate in Patients with Traumatic Brain Injuries

    Unintentional falls, particularly in the elderly, are a leading cause of traumatic brain injury (TBI)-related hospitalizations and mortality in the United States [ 1 ]. Anticoagulant use prior to injury has been associated with an increased …

  15. Open Access 01-11-2021 | Central Nervous System Trauma | OriginalPaper

    GFAP positivity in neurons following traumatic brain injuries

    Glial fibrillary acidic protein (GFAP) is a well-established astrocytic biomarker for the diagnosis, monitoring and outcome prediction of traumatic brain injury (TBI). Few studies stated an accumulation of neuronal GFAP that was observed in …

  16. 26-11-2022 | Central Nervous System Trauma | OriginalPaper

    Traumatic brain injuries are ignored or discriminated in prospective clinical trials on shoulder fractures: a systematic review

    Recent literature has revealed a significant epidemiological association between shoulder fractures and traumatic brain injuries (TBI), which can probably be explained by their shared injury mechanisms [ 1 , 2 ]. Different studies have shown that …

  17. Open Access 01-12-2021 | Central Nervous System Trauma | OriginalPaper

    Characteristics and outcome of severe traumatic brain injuries based on occupational status

    Traumatic brain injuries (TBI) have been identified as a major public health problem [ 1 , 2 ]. They are among the most important causes of morbidity and mortality among all age groups globally, they pose substantial burden on victims, their …

  18. 01-03-2022 | Central Nervous System Trauma | ReviewPaper

    Apathy and Depression as Predictors of Activities of Daily Living Following Stroke and Traumatic Brain Injuries in Adults: A Meta-Analysis

    Apathy and depression are common sequelae of acquired brain injury (ABI). Apathy is a syndrome characterized by diminished motivation and purposeful behaviours. Depression is a mood disorder featuring sadness, worthlessness, anhedonia and suicidal …

  19. Correction to: Apathy and Depression as Predictors of Activities of Daily Living Following Stroke and Traumatic Brain Injuries in Adults: a Meta‑Analysis

    A correction to this paper has been published: https://doi.org/10.1007/s11065-021-09509-0 …

  20. Open Access 01-03-2022 | Traumatic Brain Injuries | OriginalPaper

    Alcohol intoxication and lack of helmet use are common in electric scooter-related traumatic brain injuries: a consecutive patient series from a tertiary university hospital

    At the end of 2017, rental electric scooters (ESs) were first introduced into the USA as a new, nationwide means of transport. Recently, they have become a significant means of transportation for urban residents and have assumed a substantial …

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