A thorough understanding of the relationship between viruses and hematologic cancers can help clinicians to deliver precise therapies and monitor potential complications.
What are the challenges for a broad, international implementation of the current guidelines for severe community-acquired pneumonia, and how can they be overcome?
MIS-C is a relatively uncommon but severe pediatric complication associated with COVID-19, requiring rapid and intensive treatment. What are the most effective treatment strategies?
Cefepime–taniborbactam combination treatment might be a better option than meropenem for complicated urinary tract infections and acute pyelonephritis.
A review of recent AI and deep learning innovations in point-of-care lung ultrasound, including models to aid the diagnosis of conditions such as pneumonia, pulmonary edema, and pneumothorax.
Vaccinating pregnant women against respiratory syncytial virus may protect their infants from lower respiratory tract disease, but carries a risk of premature birth.
Persistent detection of SARS-CoV-2 remains a problem in immunosuppressed individuals, such as solid organ transplant recipients. The authors use a patient case to highlight the key challenges in this patient population.
Sciatica due to Streptococcus gallolyticus infection of the spinal epidural space led to a diagnosis of colorectal cancer in a person with none of the usual signs and symptoms.
In a patient with ventriculoperitoneal shunt dysfunction, exteriorization surgery revealed blue coloring of the catheter, indicating bacterial colonization. This phenomenon has been seen in urinary infections but not CNS pathologies.
Detecting DNA from cytomegalovirus, human adenovirus, BK polyomavirus, or human herpesvirus-6 in the blood of pediatric ICU patients with severe sepsis increases risk of death.
Helicobacter pylori infection is associated with an increased risk for colorectal cancer incidence and mortality, but treatment for the infection can mitigate the risk.
Tissue biopsy is the gold standard for diagnosis in T-cell lymphoma, but is not always feasible. Could liquid biopsy be used instead, and not just for diagnosis but also for monitoring treatment response?
The relationship between diabetes and infection is complex. Find out which infections are most common, what increases the risk and severity of infection, and the principles of treatment.
A case of Pneumocystis jirovecii pneumonia in a patient who presented with no known risk factors, which led to a delay in initiation of appropriate antibiotic therapy.
COVID-19 tends to be mild in children, but severe cases can have devastating impacts. What are the warning signs for deterioration? And what role does the immune system play?
Use of short courses of antibiotics in adults with ventilator-associated pneumonia does not increase their risk for death or recurrence versus standard prolonged treatment.
The novel Phoenix sepsis criteria, which are based on organ dysfunction measures, may improve the diagnosis of pediatric sepsis and septic shock compared with existing criteria.
Discover how neutrophils contribute to the development of sepsis, how the aging process impacts their functions, and the potential to enhance or curb neutrophil activity during the different phases of sepsis.
A single dose of the antibiotic ceftriaxone significantly reduces the risk for early-onset ventilator-associated pneumonia in individuals with brain injury.
WHO’s clinical definition for pediatric long COVID is a year old, but differential diagnosis remains challenging, and specific biomarkers and causal treatment options are not yet available. What’s the best approach for diagnosis and management?
