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Published in: Cardiology and Therapy 2/2024

Open Access 25-04-2024 | Heart Transplantation | Original Research

Derivation of Stroke Volume from Pulmonary Artery Pressures

Authors: Ivan H. W. Yim, Nigel E. Drury, Hoong Sern Lim

Published in: Cardiology and Therapy | Issue 2/2024

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Intermittent cardiac output (CO) studies using thermodilution are considered the gold standard. We have developed a stroke volume (SV) calculator from pulmonary pulse pressure (PP) to allow continuous monitoring of SV and CO from PP.


Hemodynamic data on 169 patients following orthotopic heart transplantation were used to compare our calculator-derived SV (and SV index, or SVi) against thermodilution-derived SV on admission into intensive care unit immediately following heart transplantation (T0) and 6 h after admission (T6).


The calculated SV correlated with thermodilution-derived SV T0 (r = 0.920, p < 0.001, coefficient of 0.539 and the constant of 2.06). The median calculator SV, adjusted for coefficient and constant, was 48.4 ml (37.7, 60.7), comparable to the median thermodilution-derived SV 47.9 ml (37.5, 61.0), p = 0.737 with acceptable agreement on Bland–Altman plots. The thermodilution-derived SVi was 28.1 ml (19.7, 38.7) and adjusted calculator-derived SVi 28.9 ml (19.7, 39.9), p = 0.781. At T6, median thermodilution-derived SVi was 27.7 ml (19.5, 35.9) compared to the calculator-derived SVi median of 26.1 ml (17.7, 37.7), p = 0.203.


Changes in PP can be used to track changes in SV using this calculator. Changes in PP may be used to assess response to treatment in the early post-operative period.
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Derivation of Stroke Volume from Pulmonary Artery Pressures
Ivan H. W. Yim
Nigel E. Drury
Hoong Sern Lim
Publication date
Springer Healthcare
Published in
Cardiology and Therapy / Issue 2/2024
Print ISSN: 2193-8261
Electronic ISSN: 2193-6544

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