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Advances in Therapy

Issue 9/2022

Content (35 Articles)

The Antifibrotic Effects of Inhaled Treprostinil: An Emerging Option for ILD

Martin Kolb, Stylianos E. Orfanos, Chris Lambers, Kevin Flaherty, Alison Masters, Lisa Lancaster, Adam Silverstein, Steven D. Nathan

Open Access Graft-Versus-Host Disease Review

The Role of Complement in HSCT-TMA: Basic Science to Clinical Practice

Seppo Meri, Donald Bunjes, Roxanne Cofiell, Sonata Jodele

Open Access Glaucoma Review

Evaluation of a Novel Αb Εxterno MicroShunt for the Treatment of Glaucoma

Barbara Burgos-Blasco, Julián García-Feijóo, Lucia Perucho-Gonzalez, Noemi Güemes-Villahoz, Laura Morales-Fernandez, Carmen D. Mendez-Hernández, Jose M. Martinez de la Casa, Anastasios G. Konstas

Open Access Schizophrenia Review

Systematic Review of Real-World Treatment Patterns of Oral Antipsychotics and Associated Economic Burden in Patients with Schizophrenia in the United States

Amber Martin, Leona Bessonova, Rachel Hughes, Michael J. Doane, Amy K. O’Sullivan, Kassandra Snook, Allie Cichewicz, Peter J. Weiden, Philip D. Harvey

Open Access Umeclidinium Review

Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Triple Therapy Compared with Other Therapies for the Treatment of COPD: A Network Meta-Analysis

Afisi S. Ismaila, Katrin Haeussler, Alexandrosz Czira, Ji-Hee Youn, Mia Malmenäs, Nancy A. Risebrough, Jatin Agarwal, Maria Nassim, Raj Sharma, Chris Compton, Claus F. Vogelmeier, MeiLan K. Han, David M. G. Halpin

Ribavirin for Treatment of Subjects with Respiratory Syncytial Virus-Related Infection: A Systematic Review and Meta-Analysis

Sofia Tejada, Raquel Martinez-Reviejo, Hanife N. Karakoc, Yolanda Peña-López, Oriol Manuel, Jordi Rello

Open Access Artificial Intelligence Review

Application of Medical Knowledge Graphs in Cardiology and Cardiovascular Medicine: A Brief Literature Review

Hong Wang, Quannan Zu, Ming Lu, Rongfa Chen, Zhiren Yang, Yongqiang Gao, Jiawang Ding

Open Access Melanoma Original Research

Adherence to Adjuvant Therapy in Patients with Resected Melanoma: An Application of the Theory of Planned Behavior

Cassie Beisel, Tayla Poretta, Vanessa B. Sheppard, Alejandra Hurtado-de Mendoza, Heather Sipsma, Eleanore Fuqua, Brian Stwalley, Anthony Salvatore, Min Yang

Obesity Original Research

Prevalence and Determinants of Sarcopenic Obesity in Older Adults: Secondary Data Analysis of the Longitudinal Ageing Study in India (LASI) Wave 1 Survey (2017–18)

Madhur Verma, Nitin Kapoor, Aditi Chaudhary, Priyanka Sharma, Nilanjana Ghosh, Shivani Sidana, Rakesh Kakkar, Sanjay Kalra

Open Access Empagliflozin Original Research

Preference for Type 2 Diabetes Therapies in the United States: A Discrete Choice Experiment

Jay H. Shubrook, Michael Radin, Sarah N. Ali, Barrie Chubb, Kristina DiPietrantonio, Hannah Collings, Robin Wyn, Martina Smith

Open Access Buprenorphine Original Research

Reduced Healthcare Resource Utilization in Patients with Opioid Use Disorder in the 12 Months After Initiation of a Prescription Digital Therapeutic

Fulton F. Velez, Kathryn P. Anastassopoulos, Samuel Colman, Neel Shah, Laura Kauffman, Sean M. Murphy, Charles Ruetsch, Yuri A. Maricich

Open Access Original Research

Real-World Reductions in Healthcare Resource Utilization over 6 Months in Patients with Substance Use Disorders Treated with a Prescription Digital Therapeutic

Neel Shah, Fulton F. Velez, Samuel Colman, Laura Kauffman, Charles Ruetsch, Kathryn Anastassopoulos, Yuri Maricich

Open Access Systemic Therapy Original Research

Real-World Effectiveness of Newly Initiated Systemic Therapy for Atopic Dermatitis in the United States: A Claims Database Analysis

Jashin J. Wu, Marie-Hélène Lafeuille, Bruno Emond, Iman Fakih, Mei Sheng Duh, Joseph C. Cappelleri, Natalie Yin, Claire Feeney, Daniela E. Myers, Marco DiBonaventura

Open Access Thrombocytopenia Original Research

Systematic Review with Meta-Analysis: Efficacy and Safety of Lusutrombopag for Severe Thrombocytopenia in Patients with Chronic Liver Disease Undergoing Invasive Procedures

Michelle E. Orme, Roy Bentley, Stephen Marcella, Markus Peck-Radosavljevic, Rodolphe Perard, Heiner Wedemeyer, Hitoshi Yoshiji, Kosh Agarwal, Geoffrey Dusheiko

Open Access Constipation Original Research

Effects of Elobixibat in Patients with Diabetes and Concomitant Chronic Constipation: an 8-week, Prospective, Single-center, Single-arm Study

Yoshiaki Hishida, Yoshio Nagai, Hidekazu Tsukiyama, Yuta Nakamura, Tomoko Nakagawa, Sonoko Ishizaki, Yasushi Tanaka, Masakatsu Sone

Open Access Obesity Original Research

The Peripheral Neuropathy Prevalence and Characteristics Are Comparable in People with Obesity and Long-Duration Type 1 Diabetes

J. Z. M. Lim, J. Burgess, C. G. Ooi, G. Ponirakis, R. A. Malik, J. P. H. Wilding, Uazman Alam

Open Access Multiple Myeloma Original Research

Indirect Treatment Comparison of Daratumumab, Pomalidomide, and Dexamethasone Versus Standard of Care in Patients with Difficult-to-Treat Relapsed/Refractory Multiple Myeloma

Jianming He, Heather Berringer, Bart Heeg, Haoyao Ruan, Tobias Kampfenkel, Harikumaran R. Dwarakanathan, Stephen Johnston, João Mendes, Annette Lam, Sacheeta Bathija, Emma K. Mackay

Lymphoma Original Research

Zanubrutinib Monotherapy for Naïve and Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Pooled Analysis of Three Studies

Wei Xu, Shenmiao Yang, Constantine S. Tam, John F. Seymour, Keshu Zhou, Stephen Opat, Lugui Qiu, Mingyuan Sun, Tingyu Wang, Judith Trotman, Ling Pan, Sujun Gao, Jianfeng Zhou, Daobin Zhou, Jun Zhu, Yuqin Song, Jianda Hu, Ru Feng, Haiwen Huang, Dan Su, Miao Shi, Jianyong Li

Open Access Aortic Valve Replacement Original Research

Comparison of Right Anterior Mini-Thoracotomy Versus Partial Upper Sternotomy in Aortic Valve Replacement

Farhad Bakhtiary, Saad Salamate, Mohamed Amer, Sami Sirat, Ali Bayram, Mirko Doss, Ali El-Sayed Ahmad

Open Access Portal Vein Thrombosis Original Research

Pharmacokinetic Assessment and Treatment Effect of Lusutrombopag in Child–Pugh Class C Patients: Review of Patient Data from Two Clinical Studies and Post-Marketing Surveillance

Steven L. Flamm, Markus Peck-Radosavljevic, Takahiro Fukuhara, Roy Bentley, Takayuki Katsube, Toshimitsu Ochiai, Takeshi Kano, Eri Tsukimura, Ritsue Sasaki, Yukio Osaki

Open Access Porphyria Variegata Original Research

Patient Perspective on Acute Hepatic Porphyria with Sporadic Attacks: A Chronic Disease with Substantial Health-Related Quality of Life Impacts

Kristen Wheeden, Desiree Lyon Howe, Sue Burrell, Liz Gill, John Chamberlayne, Edrin R. Williams, Amy Simon, John J. Ko, Jordanna Mora, Ted Wells, Christopher Evans, Maggie Paulich, Stephen Meninger, Stephen Lombardelli

Open Access Sleep Apnea Original Research

Solriamfetol Titration and AdministRaTion (START) in Patients with Obstructive Sleep Apnea: A Retrospective Chart Review and Hypothetical Patient Scenario

Haramandeep Singh, Danielle Hyman, Gregory S. Parks, Abby Chen, Catherine Foley, Beth Baldys, Diane Ito, Michael J. Thorpy

Open Access Hypertension Brief Report

Long-Term Safety, Tolerability and Survival in Patients with Pulmonary Arterial Hypertension Treated with Macitentan: Results from the SERAPHIN Open-Label Extension

Rogério Souza, Marion Delcroix, Nazzareno Galié, Pavel Jansa, Sanjay Mehta, Tomás Pulido, Lewis Rubin, B. K. S. Sastry, Gérald Simonneau, Olivier Sitbon, Adam Torbicki, Neli Boyanova, Liliya Chamitava, Claudia Stein, Richard N. Channick

Open Access Atopic Dermatitis Correction

Correction to: Epidemiology and Economic Burden of Atopic Dermatitis: Real-World Retrospective Data from a Large Nationwide Israeli Healthcare Provider Database

Clara Weil, Philip B. Sugerman, Gabriel Chodick, Huifang Liang, Hongwei Wang, Brian M. Calimlim, Ana Dorfman, Varda Shalev, Dan Ben Amitai, Yael A. Leshem

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.