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Current Nutrition Reports

It’s About Timing: Contrasting the Metabolic Effects of Early vs. Late Time-Restricted Eating in Humans

Published in:
Authors
Bernardita Sepúlveda
Andrea Marín
Raquel Burrows
Alejandro Sepúlveda
Rodrigo Chamorro
Published in
Current Nutrition Reports | Issue 2/2024

Abstract

Purpose of Review

Time-restricted eating (TRE), a form of intermittent fasting, restricts feeding time across the day, imposing a daily ‘eating window’. The time of day when the eating window occurs could result in differential metabolic effects. Here, we describe recent intervention studies in humans assessing the metabolic consequences of an early- (i.e., eating window starting in the early morning) vs. late (i.e., eating window starting after midday)-TRE protocol.

Recent Findings

Well-controlled studies indicate that both TRE protocols effectively reduce body weight and improve altered glucose metabolism, lipid profile, inflammation, or blood pressure levels. An early-TRE (e-TRE) might have a further positive impact on improving blood glucose, insulin levels, and insulin resistance. However, the studies directly assessing the metabolic consequences of an early- vs. late-TRE have shown dissimilar findings, and more well-controlled clinical trials are needed on the metabolic benefits of these two types of TRE.

Summary

Evidence suggests that an e-TRE might have enhanced metabolic results, particularly regarding glucose homeostasis. More long-term studies, including larger sample sizes, are needed to assess the metabolic, circadian, and adherence benefits, together with socio-cultural acceptance of both TRE approaches.
Title
It’s About Timing: Contrasting the Metabolic Effects of Early vs. Late Time-Restricted Eating in Humans
Authors
Bernardita Sepúlveda
Andrea Marín
Raquel Burrows
Alejandro Sepúlveda
Rodrigo Chamorro
Publication date
16-04-2024
Publisher
Springer US
Published in
Current Nutrition Reports / Issue 2/2024
Electronic ISSN: 2161-3311
DOI
https://doi.org/10.1007/s13668-024-00532-0
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