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Medical Oncology

Issue 11/2023

Content (33 Articles)

Metastasis Original Paper

C2orf48 promotes the progression of nasopharyngeal carcinoma by regulating high mobility group AT-hook 2

Yanhui Jiang, Faya Liang, Renhui Chen, Yongsheng Huang, Zhiwen Xiao, Haicang Zeng, Ping Han, Xiaoming Huang

Glucocorticoid Original Paper

Toxicity evaluation of synthetic glucocorticoids against breast cancer cell lines MDA-MB-231, MCF-7 and human embryonic kidney HEK293

Dhouha Msalbi, Fatma Jellali, Jihene Elloumi-Mseddi, Bochra Hakim, Emna Sahli, Sami Aifa

Original Paper

Decoding dysregulated angiogenesis in HTLV-1 asymptomatic carriers compared to healthy individuals

Arash Letafati, Sayed-Hamidreza Mozhgani, Arezoo Marjani, Abdollah Amiri, Zeinab Siami, Mahdi Mohammaditabar, Ghazale Molaverdi, Mojtaba Hedayatyaghoobi

Gastric Cancer Original Paper

Diosmetin induces apoptosis and protective autophagy in human gastric cancer HGC-27 cells via the PI3K/Akt/FoxO1 and MAPK/JNK pathways

Zhaobin Pan, Zhiming Tan, Hongyan Li, Yang Wang, Haiyan Du, Jinhui Sun, Chunchao Li, Shicai Ye, Xin Li, Juanhua Quan

HDAC11 mediates the ubiquitin-dependent degradation of p53 and inhibits the anti-leukemia effect of PD0166285

Ziwei Zhou, Liang Zhong, Xuan Chu, Peng Wan, Wenran Dan, Xin Shao, Shuyu Chen, Zhonghui Zhang, Yang Lu, Beizhong Liu

Breast Cancer Original Paper

Identification of novel inhibitors from Urtica spp against TNBC targeting JAK2 receptor for breast cancer therapy

Shobha Upreti, Kartik Muduli, Jagannath Pradhan, Selvakumar Elangovan, Mukesh Samant

Open Access Melanoma Original Paper

Whole-exome sequencing reveals mutational profiles of anorectal and gynecological melanoma

Wei Sun, Kunyan Liu, Hongyu Zhou, Fang Zhao, Yan Dong, Yu Xu, Yunyi Kong, Minghe Wang, Xi Cheng, Yong Chen

Glioblastoma Original Paper

Combretastatin A-4 suppresses the invasive and metastatic behavior of glioma cells and induces apoptosis in them: in-vitro study

Mostafa Karimi Roshan, Amir R. Afshari, Farshad Mirzavi, Seyed Hadi Mousavi, Mohammad Soukhtanloo

Breast Cancer Original Paper

Tamoxifen induces eryptosis through calcium accumulation and oxidative stress

Mohammad A. Alfhili, Abdulaziz M. Alyousef, Jawaher Alsughayyir

Mitoxantrone Original Paper

Multitargeted inhibitory effect of Mitoxantrone 2HCl on cervical cancer cell cycle regulatory proteins: a multitargeted docking-based MM\GBSA and MD simulation study

Mohammed Ali Alshehri, Saeed Ahmed Asiri, Abdulrahman Alzahrani, Reem S. Alazragi, Leena S. Alqahtani, Amany I. Alqosaibi, Mashael M. Alnamshan, Qamre Alam, Misbahuddin M. Rafeeq

Review Article

How gallic acid regulates molecular signaling: role in cancer drug resistance

Samira Hassani, Fahimeh Ghanbari, Marzieh Lotfi, Waqas Alam, Michael Aschner, Jelena Popović-Djordjević, Seyed Hossein Shahcheraghi, Haroon Khan

Solanum nigrum Linn.: Advances in anti-cancer activity and mechanism in digestive system tumors

Hongyu Pei, Jing Yang, Wang Li, Xing Luo, Yi Xu, Xueying Sun, Qian Chen, Qi Zhao, Li Hou, Gang Tan, Daolin Ji

CAR T-Cell Therapy Review Article

Involving stemness factors to improve CAR T-cell-based cancer immunotherapy

Sara Abdalrazzaq M. Noraldeen, Irodakhon Rasulova, Repudi Lalitha, Farah Hussin, Hashem O. Alsaab, Ahmed Hussien Alawadi, Ali Alsaalamy, Nidhal Hassan Sayyid, Adnan Taan Alkhafaji, Yasser Fakri Mustafa, Sepideh Karkon Shayan

Lung Cancer Review Article

Himalayan flora: targeting various molecular pathways in lung cancer

Abija James, K. Akash, Avinash Sharma, Sanjib Bhattacharyya, Pornsak Sriamornsak, Rupak Nagraik, Deepak Kumar

Metastasis Review Article

Theranostic signature of tumor-derived exosomes in cancer

Samruti Kumar, Rajib Dhar, Lokesh Babu Sirkali Suresh Kumar, Gauresh Gurudas Shivji, Rama Jayaraj, Arikketh Devi

Cancer Therapy Review Article

Novel biomolecules in targeted cancer therapy: a new approach towards precision medicine

Sandra Kannampuzha, Reshma Murali, Abilash Valsala Gopalakrishnan, Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Arunraj Namachivayam, Alex George, Abhijit Dey, Balachandar Vellingiri

Open Access Hepatocellular Carcinoma Review Article

Roles of circRNAs in regulating the tumor microenvironment

Tao Liu, Kaijun Long, Zhengfeng Zhu, Yongxiang Song, Cheng Chen, Gang Xu, Xixian Ke

Targeted Therapy Review Article

Unveiling the genetic and epigenetic landscape of colorectal cancer: new insights into pathogenic pathways

Humzah Postwala, Yesha Shah, Priyajeet S. Parekh, Mehul R. Chorawala

Underweight Review Article

The roles of P-selectin in cancer cachexia

Tingting Ling, Jing Liu, Liang Dong, Ju Liu

Cytokines Short Communication

Deregulation of cytokine affecting oral neutrophil subsets in oral cancer

Sudhansubala Lenka, Sanat Kumar Bhuyan, Ruchi Bhuyan

Open Access Confusion Letter to the Editor

Letter to editor: confusions about the role of RNF149 in apoptosis and PI3K/AKT signaling

Xiaobin Guo, Qian Yang, Hongxin Yang

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.