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Oncology Hematologic Cancer

Hematologic Cancer

Open Access Hodgkin Lymphoma Case Study

Hodgkin’s lymphoma masquerading as ocular inflammation

A 17-year-old presented with non-necrotizing scleritis, anterior uveitis, vitritis, yellowish chorioretinal lesions, papillitis, and vasculitis. Would you consider Hodgkin’s lymphoma in the differential diagnosis?

Editor's Choice

Managing kidney injury caused by multiple myeloma

Free for a limited time Multiple Myeloma Review

Up to half of patients with multiple myeloma can have renal injury at initial diagnosis. What are the underlying mechanisms, diagnostic approaches, and treatment strategies?

Glucocorticoid therapy in ALL

Glucocorticoids are a mainstay in the treatment of acute lymphoblastic leukemia. Understanding how to navigate short- and long-term effects and optimize regimens is crucial for continued treatment success.

APOLLO supports ATRA–ATO for high-risk APL

First-line treatment of high-risk acute promyelocytic leukemia with ATRA–ATO significantly improves event-free survival relative to standard treatment.

DREAMM-8 supports use of novel ADC in multiple myeloma

12-06-2024 Multiple Myeloma News

A combination incorporating the antibody–drug conjugate belantamab mafodotin significantly improves the outcomes of people with relapsed or refractory multiple myeloma.

Our tailored content service will keep you up to date…

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Episode 9: The gut microbiome and CAR T-cell therapy

How do nutrition, supplements and antibiotics impact patient outcomes?

Recent research suggests that the gut microbiome could be an important modulator of response to CAR T-cell therapy in patients with hematologic cancers.

Prof. Marion Subklewe takes us through the latest evidence, highlighting the impact of antibiotics, nutrition, and dietary supplements, and discusses how to devise interventions to improve patient outcomes.

Prof. Marion Subklewe
Live Webinar | 01-10-2024 | 12:30 (CEST)

Recent advances in the use of CAR T-cell therapies in relapsed/refractory diffuse large B-cell lymphoma and follicular lymphoma

Live: Tuesday 1st October 2024, 12:30-14:00 (CEST)

In this live webinar, Professor Martin Dreyling and an esteemed, international panel of CAR-T experts will discuss the very latest data on the safety, efficacy and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL, as presented at ASH 2023, EU CAR-T 2024, and EHA 2024. 

Please note, this webinar is not intended for healthcare professionals based in the US and UK.

Sponsored by: Novartis Pharma AG

Chaired by: Prof. Martin Dreyling
Developed by: Springer Healthcare

Case Studies

Hodgkin’s lymphoma masquerading as ocular inflammation

Open Access Hodgkin Lymphoma Case Study

A 17-year-old presented with non-necrotizing scleritis, anterior uveitis, vitritis, yellowish chorioretinal lesions, papillitis, and vasculitis. Would you consider Hodgkin’s lymphoma in the differential diagnosis?

Neurological complications of CAR T-cell therapy

A 38-year-old with B-cell acute lymphocytic leukemia developed a brain abnormality, detected by CT scan on day 16 following CAR T-cell infusion. How would you assess and treat her?

Primary thyroid lymphoma: a case series

Open Access Thyroid Cancer Case Study

Although rare, primary thyroid lymphoma should be considered in cases of rapidly growing goiters. Timely needle biopsy can avoid unnecessary surgery.

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine

Current Reviews

Advances in biology, diagnosis and treatment of DLBCL

Open Access Diffuse Large B-Cell Lymphoma Review Article

Diffuse large B-cell lymphoma (DLBCL), with approximately 150,000 new cases worldwide each year, represent nearly 30% of all cases of non-Hodgkin lymphoma (NHL) and are phenotypically and genetically heterogeneous. A gene-expression profile (GEP) …

Present and future of whole-body MRI in metastatic disease and myeloma: how and why you will do it

Open Access Magnetic Resonance Imaging Review Article

Metastatic disease and myeloma present unique diagnostic challenges due to their multifocal nature. Accurate detection and staging are critical for determining appropriate treatment. Bone scintigraphy, skeletal radiographs and CT have long been …

Vaccine challenges in CLL: a comprehensive exploration of efficacy of SARS-CoV-2 immunization for patients with chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is characterized by disease- and treatment-related immunosuppression. Patients with CLL comprise a vulnerable population to coronavirus disease 2019 (COVID-19), while the protective effect of COVID-19 vaccination …

Systematic review: genetic polymorphisms in the pharmacokinetics of high-dose methotrexate in pediatric acute lymphoblastic leukemia patients

Methotrexate Review Article

Variations in pharmacokinetic responses to high-dose methotrexate are essential for the prognosis and management of toxicity in the treatment of pediatric acute lymphoblastic leukemia (ALL) patients. This systematic review aimed to identify and …

Case-Based Insights: Oncology and Hematology (Link opens in a new window)


Refresh your knowledge in Oncology and Hematology: 

  • 45 clinical cases across different topics with relevant clinical images
  • Written by renowned experts 
  • Knowledge-check questions with answers
Try the first set of cases now

CME & eLearning

SPONSORED

Webinar

In this live webinar, Professor Martin Dreyling and an esteemed, international panel of CAR-T experts will discuss the very latest data on the safety, efficacy and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL, as presented at ASH 2023, EU CAR-T 2024, and EHA 2024. 

Please note, this webinar is not intended for healthcare professionals based in the US and UK. 

Sponsored by:
  • Novartis Pharma AG
Developed by: Springer Healthcare
SPONSORED

Webinar

A series of patient cases underpin this interactive webinar that aims to provide practical guidance on a multidisciplinary approach to managing patients with cutaneous T-cell lymphoma.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare
SPONSORED

Webinar

1.0 European CME credits (ECMEC®s).

Watch part 1 of the Expert Hour webinar series on CTCL where Prof. Dr. Maarten Vermeer and Prof. Dr. Rudolf Stadler focus on the challenges of early-stage cutaneous T-cell lymphoma. The experts cover: Basics of CTCL, diagnosis, management, and monitoring of mycosis fungoides at an early stage.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare

Further Reading

Advances in biology, diagnosis and treatment of DLBCL

Open Access Diffuse Large B-Cell Lymphoma Review Article

Diffuse large B-cell lymphoma (DLBCL), with approximately 150,000 new cases worldwide each year, represent nearly 30% of all cases of non-Hodgkin lymphoma (NHL) and are phenotypically and genetically heterogeneous. A gene-expression profile (GEP) …

Fully automated segmentation and volumetric measurement of ocular adnexal lymphoma by deep learning-based self-configuring nnU-net on multi-sequence MRI: a multi-center study

Open Access Magnetic Resonance Imaging Head-Neck-ENT Radiology

Ocular adnexal lymphoma (OAL) is a common orbital malignant tumor in adults and accounts for 11–55% of orbital malignancies [ 1 – 3 ]. Over the past few decades, there has been a marked rise in the incidence of OAL, adversely affecting the quality …

Routine Histopathology of Tonsillectomy Specimens, Is It Necessary? A Prospective Observational Study

Open Access Tonsillectomy Original Article

Routine histopathology of tonsillectomy specimens is not standard practice due to cost and resource constraints. This study aimed to evaluate the prevalence of abnormal histopathologies in tonsillectomy specimens to determine the necessity of …

Incidence of Malignancies and the Association with Biological Disease-Modifying Antirheumatic Drugs in Japanese Patients with Rheumatoid Arthritis: A Time-Dependent Analysis from the IORRA Patient Registry

Open Access Rheumatoid Arthritis Original Research

Patients with rheumatoid arthritis (RA) may be at an increased risk of malignancies compared with the general population [ 1 ]. This risk varies by malignancy type, as well as by race and geographic region [ 1 – 4 ].

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