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Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on adolescent vaping

LIVE: Wednesday 29th January, 18:00-19:30 CET

Growing numbers of young people are using e-cigarettes, despite warnings of respiratory effects and addiction. How can doctors tackle the epidemic, and what health effects should you prepare to manage in your clinics?
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Hematologic Cancer Lymphoma

Lymphoma

Primary vitreoretinal lymphoma mimics fungal endophthalmitis

PVRL is a life-threatening neoplasm. It can be mistaken for non-infectious uveitis, as it often presents with vitritis that responds to corticosteroids, but this case shows that it can also mimic infectious uveitis.

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Editor's Choice

Evolving strategies for addressing CAR T-cell toxicities

An overview of the most common toxicities associated with CAR T-cell therapy, highlighting risk factors, implications for critical care, and ongoing work to optimize patient experience and mitigate toxicities.

Transplantation can be omitted for certain MCL patients

Use of autologous transplantation does not improve the survival of people with mantle cell lymphoma and undetectable minimal residual disease after induction therapy.

Featuring the official presentation video

inMIND supports tafasitamab addition in follicular lymphoma

Combining tafasitamab with lenalidomide and rituximab significantly improves progression-free survival for patients with relapsed or refractory follicular lymphoma.

Featuring the official presentation video

Advances in primary CNS lymphoma

Diagnosis of PCNSL can be challenging, but genomic cfDNA testing on CSF has emerged as a new tool. The disease is now often curable in patients younger than 65 years, with several promising clinical trials ongoing for older patients.

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ASH 2024 Annual Meeting Coverage

inMIND supports tafasitamab addition in follicular lymphoma

Combining tafasitamab with lenalidomide and rituximab significantly improves progression-free survival for patients with relapsed or refractory follicular lymphoma.

Featuring the official presentation video

Read more

Transplantation can be omitted for certain MCL patients

Add-on blinatumomab improves DFS in children with ALL

Promising response to loncastuximab tesirine in lymphoma

» View more highlights on the ASH 2024 hub page

Latest News

Promising response to loncastuximab tesirine in lymphoma

Transplantation can be omitted for certain MCL patients

inMIND supports tafasitamab addition in follicular lymphoma

Benefit of pirtobrutinib in pretreated patients with CLL/SLL

Cell-free DNA predicts DLBCL treatment outcomes

Nivolumab outplays brentuximab vedotin in Hodgkin’s lymphoma

SPONSORED

Recent advances in the use of CAR T-cell therapies in relapsed/refractory diffuse large B-cell lymphoma and follicular lymphoma

In this webinar, Professor Martin Dreyling and an esteemed international panel of CAR T-cell therapy experts discuss the latest data on the safety, efficacy, and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL.

Please note, this webinar is not intended for healthcare professionals based in the US and UK.

Sponsored by:
  • Novartis Pharma AG
Chaired by: Prof. Martin Dreyling
Developed by: Springer Healthcare
Watch now

Case Studies

Primary vitreoretinal lymphoma mimics fungal endophthalmitis

PVRL is a life-threatening neoplasm. It can be mistaken for non-infectious uveitis, as it often presents with vitritis that responds to corticosteroids, but this case shows that it can also mimic infectious uveitis.

A rare case of splenic marginal zone lymphoma transformation

Splenic marginal zone lymphoma is an indolent tumor, which in this case transformed into a highly aggressive DLBCL. The authors speculate that an MYD88 mutation may have played a role in the histologic transformation.

Uncommon presentation of DLBCL

Diagnosis of diffuse large B-cell lymphoma remains a challenge due to the variety of clinical presentations. In this case, the presenting features were lesions in the upper jaw as well as chronic cough and dyspnea.

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

  • Webinar | 19-02-2024 | 17:30 (CET)

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine
Watch now

Current Reviews

ESR Essentials: imaging of lymphoma—practice recommendations by the European Society of Oncologic Imaging

Hodgkin lymphoma, all aggressive and many indolent Non-Hodgkin lymphomas (NHL) should undergo [ 18 F]FDG-PET/CT for staging and response assessment; in small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) and non-FDG-avid indolent NHL …

Safety and efficacy of CAR-T cell therapy in patients with autoimmune diseases: a systematic review

Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment of various hematological malignancies. Recently, CAR-T has been used in refractory auto-immune diseases with initial encouraging results. In this systematic review …

Comparative safety of different first-line treatments for chronic lymphocytic leukemia/small lymphocytic lymphoma: A systematic review and network meta-analysis

The first-line treatment for chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) has recently undergone major changes, and targeted therapies have ushered in a new era of CLL/SLL treatment. Scientists in different countries have …

Pediatric lymphomas: overview and diagnostic challenges

Only 10% of new lymphoma diagnoses in the USA occur in children < 15 years. Although the same diagnostic criteria apply to both adult and pediatric lymphomas, there are important differences in some lymphoma subtypes. These differences are …

Case-based insights: Oncology and hematology (Link opens in a new window)


Refresh your knowledge in oncology and hematology: 

  • 45 clinical cases across different topics with relevant clinical images
  • Written by renowned experts 
  • Knowledge-check questions with answers
Try the first set of cases now

CME & eLearning

SPONSORED

Webinar

1.5 European CME credits (ECMEC®s)

A series of patient cases underpin this interactive webinar that aims to provide practical guidance on a multidisciplinary approach to managing patients with cutaneous T-cell lymphoma.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare
SPONSORED

Webinar

In this live webinar, Professor Martin Dreyling and an esteemed international panel of CAR T-cell therapy experts discuss the latest data on the safety, efficacy, and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL.

Please note, this webinar is not intended for healthcare professionals based in the US and UK. 

Sponsored by:
  • Novartis Pharma AG
Developed by: Springer Healthcare
SPONSORED

Webinar

1.0 European CME credits (ECMEC®s).

Watch part 1 of the Expert Hour webinar series on CTCL where Prof. Dr. Maarten Vermeer and Prof. Dr. Rudolf Stadler focus on the challenges of early-stage cutaneous T-cell lymphoma. The experts cover: Basics of CTCL, diagnosis, management, and monitoring of mycosis fungoides at an early stage.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare

Further Reading

Prognosis of aggressive adult T-cell leukemia/lymphoma with central nervous system infiltration and utility of CD7 versus CADM1 flowcytometric plots of cerebrospinal fluid

The prognosis of adult T-cell leukemia/lymphoma (ATL) with primary central nervous system (CNS) involvement has been unclear since the advent of new therapies. Recently, we have shown that flow cytometric CD7/CADM1 analysis of CD4 + cells …

ESR Essentials: imaging of lymphoma—practice recommendations by the European Society of Oncologic Imaging

Hodgkin lymphoma, all aggressive and many indolent Non-Hodgkin lymphomas (NHL) should undergo [ 18 F]FDG-PET/CT for staging and response assessment; in small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) and non-FDG-avid indolent NHL …

Clinical outcomes of chimeric antigen receptor T-cell therapy following autologous hematopoietic stem cell transplantation in 38 patients with refractory/relapsed primary or secondary central nervous system lymphoma

Central nervous system lymphoma (CNSL) is typically classified into primary and secondary subtypes. Primary CNSL (PCNSL) refers to lymphoma lesions that occur in the brain tissue, meninges, eyes (vitreoretinal space), and spinal cord, generally …

Long-term Survivor of Intravascular Central Nervous System (CNS) Lymphoma: An Unusual Phenomenon

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