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Explore the interplay between diabetes and mental health conditions, the consequences and implications for clinical practice, and the role of endocrinologists in recognizing and managing psychological difficulties.
The life expectancy of people with type 1 diabetes has improved, but type 1 diabetes may accelerate aging and contribute to the development of frailty. Explore the underlying mechanisms, frailty assessment, and prevention strategies.
The novel oral GLP-1 receptor agonist orforglipron shows noninferior and potentially superior glycemic control versus oral semaglutide in type 2 diabetes, but with more gastrointestinal adverse events.
Metabolic and renal dysfunctions can influence the disease trajectory, treatment response, and prognosis of cardiomyopathies. A holistic and multidisciplinary approach is key to identifying the appropriate therapies.
SGLT2 inhibitors are linked to lower kidney, cardiovascular, and hepatic risks than DPP-4 inhibitors in patients with type 2 diabetes and liver cirrhosis.
Insulin remains key to the management of type 2 diabetes, but its role continues to evolve with the arrival of once-weekly regimens presenting new opportunities and challenges. How can once-weekly insulin therapy be implemented to optimize patient care?
Prof. Chantal Mathieu highlights how the absence of rigorous performance standards for continuous glucose monitors in Europe contributes to wide variability in device accuracy, raising important concerns about patient safety.
A unusual case of bilateral lower-leg edema that developed in an older woman with SPIDDM shortly after she started basal–bolus insulin therapy with insulin aspart and insulin degludec.
A man who achieved diabetes remission after gastric bypass presented with hypoglycemic episodes and endogenous hyperinsulinemia. Hypoglycemia resolved and fasting tests normalized when sacubitril/valsartan was discontinued due to worsening renal function.
A woman with abdominal pain was diagnosed with ureteral stones, but her pain persisted despite stent placement. A prior diagnosis of type 2 diabetes led to diabetic ketoacidosis being identified as the cause of the pain.
In 2005 the US FDA approved the first GLP-1 medicine for type 2 diabetes, marking the start of a remarkable journey that goes beyond the stimulation of insulin secretion.
Prof. Daniel Drucker gives us a fascinating insight into the early work on GLP-1 and discusses how these medicines are impacting the lives of people with diabetes and obesity. He covers what's known about how they work, treatment duration, side effects, and the role of bariatric surgery, plus what's in the pipeline in terms of drug development and the indications that GLP-1 medicines may be used to treat in the future.
Background Melatonin has demonstrated anti-inflammatory, antioxidant, and immunomodulatory properties, making it a potential adjunct in periodontal therapy. However, its systemic metabolic effects, particularly on glycemic control in patients with …
The Research Society for the Study of Diabetes in India (RSSDI) Guidelines for the Management of Diabetes in Older Adults provide evidence-based, India-specific recommendations addressing the growing challenge of type 2 diabetes mellitus (T2DM) in …
Diabetes mellitus (DM) is a multifactorial disease driven by genetic and environmental factors, with type 2 diabetes mellitus (T2DM) constituting the majority of cases. A major cause of morbidity and mortality in diabetic patients is …
Atypical diabetes subtypes and presentations are disproportionately prevalent in populations of African and Asian ancestry. This review discusses the epidemiology, clinical presentation, aetiopathogenesis and management of four atypical diabetes …
Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.
Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills with real cases, vodcasts, and interactive infographics.
Treating children with hormone disorders is complex and requires tailored management. To help you provide the most effective care, we deliver news, cases and expert reviews covering adrenal, thyroid, pituitary, growth, and puberty disorders, obesity, and diabetes.
Accurate interpretation of genetic variants in MODY genes is critical for diagnosis but remains a challenge in clinical practice. Variant classification remains challenging due to uncertainty regarding functional impact, the complexity of disease …
Autoimmune thyroid diseases (AITDs), primarily Graves’ disease (GD) and Hashimoto’s thyroiditis (HT), represent the most prevalent organ-specific autoimmune disorders (ADs) in Western countries [ 1 – 3 ]. The prevalence of HT-related hypothyroidism …
Type 2 Diabetes Mellitus (T2DM) accelerates cognitive decline rates [ 1 ], diminishes several cognitive domains [ 2 ], and increases dementia incidence [ 1 ], with declines in brain health affecting the patient's quality of life, disease …
Many people with type 2 diabetes (T2D) on insulin therapy require treatment intensification or early combination approaches, as recognised by current treatment guidelines, including the 2022 American Diabetes Association (ADA)/European Association …
This position statement of expert opinion provides detailed suggestions for the use of commercially available diabetes technology for the management of pregnancy in women with diabetes–gestational, type 1, and type 2.
Explore the interplay between diabetes and mental health conditions, the consequences and implications for clinical practice, and the role of endocrinologists in recognizing and managing psychological difficulties.
Explore the interplay between diabetes and mental health conditions, the consequences and implications for clinical practice, and the role of endocrinologists in recognizing and managing psychological difficulties.