Pain symptoms from PDN can disrupt sleep, and disordered sleep can exacerbate pain. Learn about promising treatments for disordered sleep in people with PDN and the efficacy of treatments in improving pain and/or sleep quality.
Raised YKL-40 levels are associated with an increased risk for obesity-related and gastrointestinal cancers, particularly liver cancer, in people with type 2 diabetes.
Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.
Childhood obesity is a growing global health concern, but how should obesity be defined and measured in children, and how does it impact health in the short and long term?
Explore the clinical potential of type 2 diabetes-related PGSs for risk prediction and screening of type 2 diabetes and its comorbidities and risk stratification, with attention to their global applicability.
Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.
With the growing importance of primary care in diabetes, this podcast discusses the evidence on continuous glucose monitoring (CGM) use, the role of primary healthcare, and practical tips for interpreting the ambulatory glucose profile (AGP) report.
Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.
Complete heterozygous deletion of HNF1B was incidentally discovered in a woman who was enrolled in a clinical trial for type 1 diabetes and received immunosuppressive treatment for 4 years when she was a child.
Adding empagliflozin to sulfonylurea improved glycemic control in a woman with maturity-onset diabetes of the young. No adverse effects were noted, including no increase in ketonemia or ketonuria.
C-reactive protein (CRP) has been shown to be one of the top biomarkers for predicting future primary and secondary cardiovascular events and is one of the most studied biomarkers (Arroyo-Espliguero et al. 2021 ; van Holten et al. 2013 ). The …
Type 1 diabetes (T1D) remains one of the most prevalent chronic illnesses diagnosed in childhood, and is an immune-mediated disease directed against pancreatic β-cells, resulting in severe endogenous insulin deficiency and subsequent hyperglycemia …
Fecal microbiota transplantation (FMT) has emerged as a potential therapeutic strategy for modulating gut dysbiosis in diabetes mellitus. This review critically evaluates preclinical and clinical evidence on FMT in type 1 (T1D) and type 2 diabetes …
Diabetes mellitus is a metabolic disorder, characterized by elevated blood sugar levels (hyperglycemia) and insulin dysregulation. This disease is associated with morbidity and mortality, including significant potential vascular complications.
Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.
Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.
Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills.
Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.
This program is not available to users in the UK and US.
Treating children with hormone disorders is complex and requires tailored management. To help you provide the most effective care, we deliver resources covering adrenal, thyroid, pituitary, growth, and puberty disorders, obesity, and diabetes.
Acute leukemia is the most common malignancy in children, yet its etiology remains largely unknown. Several somatic changes are required for the development of leukemia, and according to a prevailing hypothesis, the first often occurs during fetal …
Despite advances in glycaemic management, people with type 1 diabetes remain at higher risk of CVD and CVD-related mortality than people without diabetes [ 1 ]. Data from the Swedish National Diabetes Register (NDR) reveal that people with type 1 …
Gestational diabetes mellitus (GDM) represents a significant health challenge, with prevalence rates ranging from 3 to 25%, depending on ethnic composition, diagnostic criteria employed, and underlying population characteristics [ 1 , 2 ]. This …
Estimates of the GFR (eGFR) are similar regardless of whether they are generated from creatinine-based (eGFR creat ) or cystatin C-based (eGFR cyst ) equations in most individuals. However, substantially discordant eGFR creat and eGFR cyst results …
Shorter sleep duration and both regular and occasional snoring are linked to an increased risk for type 2 diabetes in women with a history of gestational diabetes.
A thorough overview of the safety and efficacy of once-weekly basal insulin icodec in type 1 and 2 diabetes, covering pharmacology, pharmacokinetics, adverse effects, drug interactions, and dose recommendations.
Pain symptoms from PDN can disrupt sleep, and disordered sleep can exacerbate pain. Learn about promising treatments for disordered sleep in people with PDN and the efficacy of treatments in improving pain and/or sleep quality.
