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Clinical Collections
Women’s Health Knowledge Hub Advances in Alzheimer’s

Navigating neuroimaging in Alzheimer disease care

PET imaging is playing an increasingly critical role in managing AD, but how can you effectively integrate it into clinical practice? Our expert-led program will empower you with practical strategies and real-world case studies.

This content is intended for healthcare professionals outside of the UK.
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Diabetes Type 2 Diabetes

Type 2 Diabetes

Disordered sleep and painful diabetic neuropathy

Pain symptoms from PDN can disrupt sleep, and disordered sleep can exacerbate pain. Learn about promising treatments for disordered sleep in people with PDN and the efficacy of treatments in improving pain and/or sleep quality.

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Editor's Choice

YKL-40 linked to GI cancer risk in type 2 diabetes

Raised YKL-40 levels are associated with an increased risk for obesity-related and gastrointestinal cancers, particularly liver cancer, in people with type 2 diabetes.

Skin infection or lymphoma in a woman with type 2 diabetes?

Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.

The threat of childhood obesity

Childhood obesity is a growing global health concern, but how should obesity be defined and measured in children, and how does it impact health in the short and long term?

Clinical use of polygenic scores in type 2 diabetes

Explore the clinical potential of type 2 diabetes-related PGSs for risk prediction and screening of type 2 diabetes and its comorbidities and risk stratification, with attention to their global applicability.

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Keynote series | Spotlight on managing health in obesity

Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.

Prof. Eva L. Feldman
Prof. Jonette Keri
Developed by: Springer Medicine
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Video

Latest News

YKL-40 linked to GI cancer risk in type 2 diabetes

GLP-1 RAs may reduce dementia risk

GLP-1 RA plus thiazolidinedione has CV benefits in type 2 diabetes

Dulaglutide to tirzepatide switch outperforms dulaglutide escalation for type 2 diabetes control

STRIDEs made for type 2 diabetes plus peripheral artery disease

CV efficacy of oral semaglutide confirmed for high-risk type 2 diabetes

Using CGM to optimize type 2 diabetes management with non-intensive insulin treatment in primary care

With the growing importance of primary care in diabetes, this podcast discusses the evidence on continuous glucose monitoring (CGM) use, the role of primary healthcare, and practical tips for interpreting the ambulatory glucose profile (AGP) report. 

Supported by:
  • Abbott Diabetes Care
Prof. Samuel Seidu
Developed by: Adis
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Podcast

Case Studies

Skin infection or lymphoma in a woman with type 2 diabetes?

Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.

SGLT2 inhibitor triggers metabolic encephalopathy

Testing ketone levels and a brain MRI are essential for unconscious patients on SGLT2 inhibitors. Patients on these drugs are at increased risk of euglycemic diabetic ketoacidosis, which may cause metabolic encephalopathy.

Accidental use of dulaglutide into the third trimester

The GLP-1 receptor agonist dulaglutide was unintentionally used by a woman with type 2 diabetes until the third trimester of an unplanned and unrecognized pregnancy, but what was the outcome?

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
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Current Reviews

Dose-dependent effects of omega-3 polyunsaturated fatty acids on C-reactive protein concentrations in cardiometabolic disorders: a dose–response meta-analysis of randomized clinical trials

C-reactive protein (CRP) has been shown to be one of the top biomarkers for predicting future primary and secondary cardiovascular events and is one of the most studied biomarkers (Arroyo-Espliguero et al. 2021 ; van Holten et al. 2013 ). The …

The role of fecal microbiota transplantation in diabetes

Fecal microbiota transplantation (FMT) has emerged as a potential therapeutic strategy for modulating gut dysbiosis in diabetes mellitus. This review critically evaluates preclinical and clinical evidence on FMT in type 1 (T1D) and type 2 diabetes …

Treat metabolic diseases with effective and approved therapies while new treatments are under investigation

Management of metabolic diseases, such as obesity and type 2 diabetes, typically requires pharmacotherapeutics in addition to lifestyle changes. Several glucagon-like peptide-1 receptor (GLP-1R) agonists have acquired US FDA approval for treatment …

Burden of diabetes mellitus on health and economy of the Arab world: current situation and perspectives

Diabetes mellitus, once regarded as a minor global health concern, is now recognized as a major threat to human well-being in this century. The rising epidemic of type 2 diabetes mellitus (T2DM) is primarily driven by factors such as population …

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.

Developed by: Springer Medicine
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CME & eLearning

Videos | Case Scenarios | Infographics (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)™

Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Vodcasts | Case Scenarios (Link opens in a new window)

Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

News | Expert Reviews | Cases (Link opens in a new window)

Treating children with hormone disorders is complex and requires tailored management. To help you provide the most effective care, we deliver resources covering adrenal, thyroid, pituitary, growth, and puberty disorders, obesity, and diabetes.

Supported by:
  • Merck Healthcare KGaA, Darmstadt, Germany
Developed by: Springer Healthcare IME

Further Reading

Testosterone Therapy in Older Men: Present and Future Considerations

Testosterone is the classical male anabolic hormone, involved in sexual development, virilisation and regulation of body composition in adult men. Organic disease involving the hypothalamus, pituitary or testes may interfere with endogenous …

One-Year Outcomes of SADI-S in Chinese Patients with Type 2 Diabetes and BMI < 35 kg/m2: A Single-Center Retrospective Study

The incidence of diabetes is increasing annually alongside the rapid development of the social economy. As a chronic disease that significantly impacts human health, diabetes and its complications not only reduce the quality of life and require …

The relationship between shrunken pore syndrome and all-cause mortality in people with type 2 diabetes and normal renal function: the Fremantle Diabetes Study Phase II

Estimates of the GFR (eGFR) are similar regardless of whether they are generated from creatinine-based (eGFR creat ) or cystatin C-based (eGFR cyst ) equations in most individuals. However, substantially discordant eGFR creat and eGFR cyst results …

Pharmacokinetics and Pharmacodynamics of Prusogliptin (DBPR108), a Once-Daily Dipeptidyl Peptidase-4 Inhibitor, in Patients with Type 2 Diabetes

Dipeptidyl peptidase‐4 (DPP-4) inhibitors are a class of oral antidiabetic agents that inhibit the degradation of the incretins, mainly glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) [ 1 ]. GLP-1 stimulates …

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